Jun 24th, 2022 - The more years a person drinks alcohol, the kind of alcohol consumed, and the amount consumed can help to predict gout tophi, researchers say in a newly published paper in Arthritis Care and Research. The study, led by Lin Han, PhD, of the gout laboratory, Shandong provincial clinical research center for immune diseases and gout, Affiliated Hospital of Qingdao (China) University, helps clarify.

Jun 24th, 2022 - Racial residential segregation was significantly associated with poor glycemic control in Black adolescents with type 1 diabetes, according to data from 144 individuals. Racial residential segregation is considered a form of systemic racism that involves limited access to resources, including health care resources, Deborah A.

Jun 24th, 2022 - Pain is common in patients with cirrhosis, and its management presents significant challenges to health care providers, such as worries about GI bleeding, renal injury, falls, and hepatic encephalopathy. To address those issues, researchers at the University of Michigan, Ann Arbor, authored a review, published in Hepatology, that describes the pain syndromes experienced by patients, as well as.

Jun 24th, 2022 - One of the most common procedures in gastroenterology – esophagogastroduodenoscopy (EGD) – needs to consistently meet quality measures, but data on interventions to improve them is lacking, according to a recent review. Researchers, led by Fateh Bazerbachi, MD, with CentraCare, Interventional Endoscopy Program, at St.

Jun 24th, 2022 - Alexa Mieses Malchuk, MD, MPH Mr L was a young man coming to see me for the first time. The reason for the visit was to establish care with a new primary care clinician, but he was also experiencing insomnia. In the past, Mr L has been afflicted with depression, usually induced by life stressors. For example, he struggled with mood symptoms after the birth of his second child a few years ago. A...

Jun 23rd, 2022 - Key clinical point: The pediatric hepatocellular carcinoma (HCC) subtypes fibrolamellar carcinoma (FLC) and conventional HCC (cHCC) can be considered nonequivalent entities because they show different anatomic patterns and outcomes together with their known molecular differences. Major finding: HCC subtypes were significantly different in presentation and behavior, with increased lymph node inv.

Jun 23rd, 2022 - Key clinical point: Nivolumab may serve as a first-line systemic treatment option in patients with hepatocellular carcinoma (HCC) and Child-Pugh B (CP-B) cirrhosis. Major finding: Patients receiving nivolumab vs.

Jun 23rd, 2022 - Key clinical point: In estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2−) breast cancer (BC) neoadjuvant chemotherapy (NAC) should be considered to enable axillary conservation in patients aged <50 years with Ki67 ≥20%. Major finding: Both Ki67 ≥20% (adjusted odds ratio [aOR] 2.

Jun 23rd, 2022 - Key clinical point: Elacestrant significantly improved progression-free survival (PFS) compared with standard-of-care (SOC) endocrine monotherapy in previously treated patients with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2−) metastatic breast cancer (BC) with a manageable safety. Major finding: Elacestrant vs.

Jun 23rd, 2022 - Key clinical point: Probiotic supplementation reduced the clinical severity of atopic dermatitis (AD) and improved the quality of life (QoL) in adults with AD compared with control intervention. Major finding: Probiotic vs.

Jun 23rd, 2022 - Key clinical point: Patients with atopic dermatitis (AD) experience a fluctuation in depression severity over time, with the likelihood of experiencing depressive symptoms being the highest in patients with severe AD. Major finding: Among patients with ≥2 follow-up visits, most (49.

Jun 23rd, 2022 - For generally healthy patients taking isotretinoin for acne and who have no underlying abnormalities or preexisting conditions that warrant further examination, it is sufficient to test ALT and triglycerides once at baseline, ideally within a month prior to the start of treatment, and a second time at peak dose. Other tests such as complete blood cell counts and basic metabolic panels as well a.

Jun 23rd, 2022 - For children and young people, skin disorders can have a devastating impact on physical and mental wellbeing, yet effective treatments are few and far between. That’s why the Medical Research Foundation is pledging £1 million of new funding to help advance scientific understanding of these conditions, which could ultimately lead to improved support and treatment for children and young people li...

Jun 23rd, 2022 - A new tool can help streamline diagnosis and treatment of migraine in the primary care setting, new research suggests. Early results from a small pilot study showed that the tool, essentially a medical record "best-practice alert," reduces specialist referrals and MRI studies. Dr Scott Friedenberg The idea behind the tool is to give primary care physicians "fingertip access" to prompts on patie...

Jun 23rd, 2022 - MADRID (Reuters) - Seville has introduced a pioneering system to name and classify frequent heatwaves that affect the city in Spain's arid south, which will tie meteorological forecasts to health impacts, Seville Mayor Antonio Munoz said. The pilot project comprises three categories and will alert the population up to five days in advance of a heat event, he said in a statement late on Tuesday....

Jun 23rd, 2022 - NEW YORK (Reuters Health) - Serious injuries may be more likely when kids use trampolines at specialized centers than when using trampolines at home, a new study suggests. A reanalysis of data from 11 previous studies that included nearly 14 million injuries revealed a more than two-fold increase in the likelihood of musculoskeletal and/orthopedic injuries at trampoline centers compared with ho...

Jun 23rd, 2022 - BRUSSELS (Reuters) - The European Commission proposed on Wednesday legally binding targets to halve the use of chemical pesticides and restore nature across the EU, in an attempt to better protect health and recover plunging wildlife populations. European Union environment policy chief Virginijus Sinkevicius told Reuters the proposal on repairing habitats would require EU countries to take step...

Jun 23rd, 2022 - LONDON (Reuters) - Leaders of the global scheme aiming to get COVID-19 vaccines to the world's poorest are pushing manufacturers including Pfizer and Moderna to cut or slow deliveries of about half a billion shots so doses are not wasted. COVAX, the World Health Organization-led scheme, wants between 400 and 600 million fewer vaccines doses than initially contracted from six pharmaceutical comp...

Jun 23rd, 2022 - VALLETTA (Reuters) - An American couple on Wednesday appealed to the Maltese authorities to let them leave Malta to have an abortion and avoid any risks to the mother after she suffered symptoms of a miscarriage. Malta is the only country in the European Union which does not allow abortion under any circumstances. Andrea Prudente and her partner Jay Weeldreyer, from Seattle, were on holiday on ...

Jun 23rd, 2022 - The study was published on researchsquare.com as a preprint and has not yet been peer reviewed. Key Takeaway Regarding consolidation therapy for younger patients with acute myeloid leukemia (AML), there was no survival benefit from taking high-dose vs intermediate-dose cytarabine. Why This Matters Numerous trials comparing high and intermediate doses for consolidation have not shown an advantag...