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About 13,408 results

SCAI Issues Guidelines for PFO Management, Makes Case for Expansion
https://www.medscape.com/viewarticle/974398

May 20th, 2022 - The first-ever guidelines for interventional cardiologists using percutaneous patent foramen ovale closure recommend expanding the use of the procedure beyond the Food and Drug Administration-approved indication following PFO-associated ischemic stroke, adding clarification about the use of PFO with anticoagulation and hedging against abuse and overuse of the procedure, said the chair of the gu...

Genomic Risk Score Predicts Intracerebral Hemorrhage Risk
https://www.medscape.com/viewarticle/974319

May 19th, 2022 - The study covered in this summary was published in medRxiv.org as a preprint and has not yet been peer reviewed. Key Takeaway When added to clinical risk factors, a validated genomic risk score can predict the lifetime risk of intracerebral hemorrhage in individuals of European ancestry. Why This Matters Prediction for intracerebral hemorrhage could be improved by adding genomic information to ...

High IL-6 Levels Linked to Carotid Plaque Severity, Progression
https://www.medscape.com/viewarticle/974221

May 18th, 2022 - Increased circulating levels of the cytokine interleukin 6 (IL-6) are associated with carotid plaque severity and progression, contributing to an increased risk of stroke, a new study suggests. The researchers also identified an IL-6 level cutoff that might help clinicians identify patients who could benefit from specific anti-IL-6 treatments. "One of the major conclusions that we could draw fr...

Updated AHA/ASA Guideline Changes Care for Spontaneous Intracerebral Hemorrhage
https://www.medscape.com/viewarticle/974141

May 17th, 2022 - Many strategies widely considered "standard care" for managing spontaneous intracerebral hemorrhage (ICH) are not as effective as previously thought and are no longer recommended in updated guidelines from the American Heart Association (AHA)/American Stroke Association (ASA). Compression stockings, antiseizure medication, and steroid treatment are among the treatments with uncertain effectiven...

Fast Five Quiz: Type 2 Diabetes and Dyslipidemia
https://www.medscape.com/viewarticle/970507

May 16th, 2022 - Type 2 diabetes is a complex metabolic disorder, leading to increased morbidity, mortality, and cost. Dyslipidemia is a common condition coexisting with type 2 diabetes and a clear risk factor for the development of atherosclerotic cardiovascular disease (ASCVD). Primary and secondary prevention of cardiovascular events is essential to the management of type 2 diabetes. Despite the progress in ...

A Surprise and a Mystery: NAFLD in Lean Patients Linked to CVD Risk
https://www.medscape.com/viewarticle/973925

May 13th, 2022 - People with nonalcoholic fatty liver disease (NAFLD) and a lean or healthy body mass index (BMI) are at increased risk for peripheral vascular disease, stroke, and cardiovascular disease, a surprise finding from a new study reveals. "Our team had expected to see that those with a normal BMI would have a lower prevalence of any metabolic or cardiovascular conditions," lead researcher Karn Wijarn...

Recurrent Stroke Risk High in AF, Even With Anticoagulants
https://www.medscape.com/viewarticle/973963

May 13th, 2022 - Patients with atrial fibrillation (AF) who suffer an ischemic stroke while taking direct oral anticoagulants (DOACs) or vitamin K antagonists (VKA) have a dangerously high risk of recurrent stroke and death, a new study shows. Researchers found a mortality rate of just over 12% within 3 months of an ischemic stroke on oral anticoagulation and close to 20% at 1 year, which they said demonstrates...

Stroke in the Young: Cancer in Disguise?
https://www.medscape.com/viewarticle/973973

May 13th, 2022 - Young stroke patients have an increased risk of being diagnosed with a new cancer in the years following their stroke, a new study shows, raising the possibility that the stroke might be the first manifestation of an underlying cancer. The data were presented by Jamie Verhoeven, MD, Radboud University Medical Centre, Netherlands, at the recent European Stroke Organisation Conference 2022. Verho...

Life Expectancy Important When Deciding on Intensive BP Lowering
https://www.medscape.com/viewarticle/973710

May 12th, 2022 - NEW YORK (Reuters Health) - Starting intensive antihypertensive therapy may be most appropriate for adults expected to live at least three more years. For those with a life expectancy of less than one year, the harms of intensive BP control may outweigh the benefits. These are the chief findings from a "time to clinical benefit" analysis of individual patient data from six randomized controlled...

Uncertain Results for Tenecteplase in 'Wake-up' Stroke
https://www.medscape.com/viewarticle/973876

May 12th, 2022 - In patients with "wake-up" stroke selected by noncontrast CT, treatment with tenecteplase did not significantly improve functional outcome at 90 days in the TWIST trial. Although tenecteplase treatment was associated with a higher proportion of patients achieving an excellent functional outcome, this was not statistically significant, and symptomatic intracranial hemorrhage was numerically high...

Second Trial Shows Thrombectomy Benefit in Basilar Artery Stroke
https://www.medscape.com/viewarticle/973765

May 11th, 2022 - A second randomized controlled trial in the space of 3 days has shown benefit of endovascular thrombectomy for the treatment of stroke caused by basilar artery occlusion. The Basilar Artery Occlusion Chinese Endovascular (BAOCHE) trial was presented at the European Stroke Organisation Conference (ESOC) 2022 on May 6. Just 2 days earlier, a similar trial (ATTENTION) was presented at the same mee...

Espresso Coffee Associated With Increased Total Cholesterol
https://www.medscape.com/viewarticle/973819

May 11th, 2022 - Espresso consumption is associated with higher total cholesterol levels, a population-based, cross-sectional study suggests. Elevations in serum total cholesterol level were significantly linked to espresso consumption, particularly in men, report Åsne Lirhus Svatun, of the the Arctic University of Norway, in Tromsø, Norway, and colleagues. Drinking boiled/plunger coffee was associated with si...

Exenatide Linked to Less Hyperglycemia After Stroke
https://www.medscape.com/viewarticle/973840

May 11th, 2022 - Treatment with the diabetes drug exenatide was associated with a significant decrease in hyperglycemia in acute stroke patients, a new study shows. The research could offer clinicians an alternative to insulin therapy to treat hyperglycemia and reduce glucose levels, which are elevated in up to 60% of stroke patients and associated with worse outcomes after stroke. "Use of these diabetes drugs ...

Taking ICH Cases Straight to Endovascular Center May Cause Harm
https://www.medscape.com/viewarticle/973834

May 11th, 2022 - Direct transport of patients with a hemorrhagic stroke to a more distant comprehensive stroke center, rather than taking them to the nearest local primary stroke center, resulted in a strong trend toward a worse outcome and higher mortality, a new analysis of the RACECAT trial shows. "There is still room for improvement in prehospital care and better triage tools for patients with intracerebral...

Medical Education Programs Tell How Climate Change Affects Health
https://www.medscape.com/viewarticle/973743

May 10th, 2022 - Madhu Manivannan, a third-year student at Emory School of Medicine, is on the vanguard of a new approach to clinical education. Manivannan, co-president of Emory Medical Students for Climate Action, was in the first class of Emory's medical students to experience the birth of a refined curriculum ― lobbied for and partially created by students themselves. The new course of study addresses the m...

Five New Neurology Studies: Possible Breakthroughs, Some Failures
https://www.medscape.com/viewarticle/972485

May 9th, 2022 - This transcript has been edited for clarity. Dear colleagues, I'm Christoph Diener from the University of Duisburg-Essen in Germany. Today, I would like to report on five exciting studies from March 2022. Cell Therapy for Duchenne Muscular Dystrophy I would like to start with what I consider a landmark paper in The Lancet about the future therapy of Duchenne muscular dystrophy. You all know thi...

Neurology, Psychiatry Studies Overlook Sex as a Variable
https://www.medscape.com/viewarticle/973633

May 9th, 2022 - A large percentage of studies in neurology and psychiatry over the past decade have failed to account for differences between the sexes, according to a team of Canadian researchers. In a survey of more than 3000 papers published in six neuroscience and psychiatry journals from 2009 to 2019, researchers found that only 5% analyzed sex as a variable. Liisa A.M. Galea, PhD "Despite the fact there ...

No Benefit to Early Tracheostomy in Severe Stroke
https://www.medscape.com/viewarticle/973654

May 9th, 2022 - Early tracheostomy offers no significant improvement in survival without severe disability than the standard approach to tracheostomy in patients on mechanical ventilation following a severe stroke, a new study shows. Researchers say that while the findings suggest both approaches are safe, there may still be advantages to delaying tracheostomy in these patients. "Our results are neutral in the...

Fast Five Quiz: Alzheimer's Disease
https://reference.medscape.com/viewarticle/972694

May 6th, 2022 - Worldwide, more than 55 million individuals are currently living with dementia, with Alzheimer's disease accounting for as much as 70% of cases. As many as 15 million US citizens were living with Alzheimer's disease in 2020, a number expected to triple by 2060. Recent research has provided new insights into possible causes and potential treatments. Given the rapidly increasing incidence of this...

Endovascular Benefit Finally Confirmed for Basilar Artery Stroke
https://www.medscape.com/viewarticle/973547

May 6th, 2022 - The benefit of endovascular therapy in the treatment of stroke caused by an occlusion of the basilar artery has finally been confirmed in the ATTENTION randomized trial. The study, conducted in China, showed that endovascular therapy for basilar artery occlusion is associated with higher rates of favorable and independent outcomes, as well as lower overall disability and lower mortality at 90 d...