Jan 30th, 2023 - The FDA approved the selective estrogen receptor (ER) degrader elacestrant (Orserdu) for the treatment of postmenopausal women or adult men with ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy. The FDA also approved the Guardant360 CDx assay as a companion diagnostic test to identify patients...

Jan 30th, 2023 - Patients with systemic lupus erythematosus (SLE) showed reduced antibody responses following COVID-19 vaccination, with drugs for the condition such as belimumab (Benlysta) and mycophenolate mofetil (MMF) likely to blame, researchers said. Immunoglobulin G (IgG) titers measured 2 weeks after the second dose of mRNA COVID vaccines were lower by about 20% among 342 lupus patients compared with th...

Jan 30th, 2023 - Note that some links may require subscriptions. The medical response following the beating of Tyre Nichols by Memphis police is being questioned; now two emergency medical technicians (EMTs) have been suspended pending an investigation. (New York Times) COVID-19 is still a global health emergency, the World Health Organization said, though it may be reaching a turning point. (AP) Meanwhile, the...

Sovos Brands Intermediate, Inc. ("Sovos") is voluntarily recalling a limited number of 16-ounce jars of Rao's Made for Home Slow Simmered Soup, Chicken & Gnocchi, because the affected jars may contain undeclared egg.

Ameripack Foods LLC of Hughes Springs, TX is issuing a recall for 976lbs. of brownies for H-E-B Meal Simple Chocolate Chunk Brownie 13 Oz due to an undeclared - Soy & Egg. People who have an allergy or severe sensitivity to soy or egg run the risk of serious or life-threatening allergic reaction if

Daiso California LLC of La Mirada, CA is recalling Tohato Nagewa Snack (skus 4901940112036 & 4901940112005) because it contains an undeclared milk derivative ingredient. People who have an allergy or severe sensitivity to milk run the risk of serious or life-threatening allergic reaction if they co

Caesar's Pasta, LLC of Blackwood, NJ is recalling 5,610 lbs. of frozen manicotti, because it has the potential to be contaminated with Listeria monocytogenes, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immun

Sovos Brands Intermediate, Inc. ("Sovos") is voluntarily recalling a limited number of 16-ounce jars of Rao's Made for Home Slow Simmered Soup, Chicken & Gnocchi, because the affected jars may contain undeclared egg.

Jan 27th, 2023 - Steven R. Feldman, MD, PhD I suspect lebrikizumab is going to be another excellent atopic dermatitis (AD) treatment option.

Jan 27th, 2023 - A 4-MONTH-OLD HISPANIC INFANT was brought to her pediatrician by her parents for evaluation of a dark red lesion over her right eyelid. The mother said that the lesion appeared when the child was 4 weeks old and started as a small red dot.

Jan 27th, 2023 - AURORA, COLO. – The therapeutic action of 5-aminosalicylic acid (5-ASA), one of the most frequently prescribed drugs for inflammatory bowel disease (IBD), can be defeated by enzymes that reside in the very gut that the drug is designed to treat.

Jan 27th, 2023 - Children with peanut allergies may benefit from an unusual oral immunotherapy regimen: boiled peanuts. Use of a boiled peanut regimen led to desensitization in 80% of children with peanut allergies enrolled in an open-label, phase 2 trial, which was published in Clinical & Experimental Allergy. Few children withdrew from the trial because of adverse events. “Small and increasing doses of boiled...

Jan 27th, 2023 - As researchers continue to seek insights to improve the understanding, prevention, and treatment of Alzheimer disease and related dementias (ADRD), a growing body of research highlights significant racial and ethnic disparities in various aspects of these diseases.1 “In Blacks and Hispanics, the prevalence of ADRD is 1.5 to 2 times higher compared to non-Hispanic Whites,” said Timothy S. Chang,...

Jan 27th, 2023 - The FDA announced that the Oncologic Drugs Advisory Committee (ODAC) will meet March 9 to review the accelerated approval of polatuzumab vedotin (Polivy) plus rituximab (Rituxan) and chemotherapy for untreated diffuse large B-cell lymphoma. Janssen and Legend Biotech announced early termination of a phase III trial after an interim analysis showed that ciltacabtagene autoleucel (cilta-cel, Carv...

Jan 27th, 2023 - The FDA's vaccine advisors unanimously backed the agency's proposal to harmonize COVID-19 primary and booster vaccines to contain a single bivalent composition with components targeting BA.4/5 and the original SARS-CoV-2 strain. With a 21-0 vote on Thursday, members of the Vaccines and Related Biological Products Advisory Committee (VRBPAC) supported FDA's plan, which aims to offer better prote...

January 26, 2023, Joy Joy's Bakery Lakewood, Washington is recalling Ube Spanish Bread, Ube Ensaymada, and Ube Roll because it may contain undeclared wheat. People who have an allergy or severe sensitivity to wheat run the risk of serious or life-threatening allergic reaction if they consume this p

January 26, 2023, Joy Joy's Bakery Lakewood, Washington is recalling Ube Spanish Bread, Ube Ensaymada, and Ube Roll because it may contain undeclared wheat. People who have an allergy or severe sensitivity to wheat run the risk of serious or life-threatening allergic reaction if they consume this p

Jan 27th, 2023 - AOAC INTERNATIONAL Executive Director David B. Schmidt is pleased to announce that Dr. Katerina (Kate) Mastovska has been named Deputy Executive Director and Chief Science Officer. Two current staff members, each with almost 20 years of experience at AOAC, Dawn L. Frazier and Deborah McKenzie, have been promoted to new roles at the nonprofit organization which ensures the safety and integrity o...

Jan 27th, 2023 - A large clinical study is now beginning on an approved drug for treating psoriasis. The drug will be tested on patients who were recently diagnosed with type 1 diabetes. The theory is that the drug could preserve the patient’s remaining insulin production. A large number of hospitals throughout Sweden are participating in this large project, which is funded by the Swedish Research Council withi...

Jan 27th, 2023 - FOR IMMEDIATE RELEASE Findings from a Johns Hopkins Children’s Center study in animal models show that a U.S. Food and Drug Administration (FDA)-approved antibiotic regimen for multidrug-resistant (MDR) tuberculosis (TB) may not work for TB meningitis. Studies in a small number of people also provide evidence that a new combination of drugs is needed to develop effective treatments for TB menin...