About 55,258 results

Atezolizumab Provides Option for Patients With NSCLC at High Risk of Recurrence

Dec 2nd, 2021 - Adjuvant atezolizumab (Tecentriq) outperformed best supportive care according to results from the phase 3 IMpower010 trial (NCT02486718), which supported FDA approval of the agent for patients with stage II to IIIA non–small cell lung cancer (NSCLC) with PD-L1 expression on at least 1% of tumor cells following resection and platinum-based chemotherapy.1 Investigator-assessed disease-free surv...

First Omicron Case Detected in the U.S.

Dec 1st, 2021 - The U.S. confirmed its first case of the Omicron variant (B.1.1.529) on Wednesday, the CDC announced. The California and San Francisco departments of public health confirmed the case in a recent traveler returning from South Africa, according to a statement. They added that the individual was fully vaccinated and had "mild symptoms that are improving." Close contacts tested negative and the ind...

Next-Gen MRD Testing Predicts Acute Leukemia Relapse After CAR-T

Dec 1st, 2021 - Next-generation sequencing-based detection of minimal residual disease (NGS-MRD) was highly predictive for the risk of relapse in children or young adults with acute lymphoblastic leukemia (ALL) after treatment with the chimeric antigen receptor (CAR) T-cell therapy tisagenlecleucel (Kymriah), according to a new study. At every timepoint from 3 to 12 months after treatment, detectable disease b...

US STOCKS-Wall St ends lower as taper acceleration worries pile onto virus angst

Nov 30th, 2021 - (For a Reuters live blog on U.S., UK and European stock markets, click LIVE/ or type LIVE/ in a news window) (Updates with close of U.S. market, adds commentary) Nov 30 (Reuters) - Wall Street’s main indexes closed lower on Tuesday after Federal Reserve Chair Jerome Powell signaled that the U.S. central bank would consider speeding up its withdrawal of bond purchases as inflation risks increase...

US STOCKS-Wall St sinks as taper acceleration worries pile onto virus angst

Nov 30th, 2021 - (For a Reuters live blog on U.S., UK and European stock markets, click LIVE/ or type LIVE/ in a news window) * Communications services, materials lead sector declines * Fed’s Powell floats dropping “transitory” label for inflation * U.S. consumer confidence ebbs in November * Indexes down: Dow 1.44%, S&P 1.34%, Nasdaq 1.25% (Updates prices, adds commentary, byline) By Devik Jain, Ambar Warrick ...

UAMS Winthrop P. Rockefeller Cancer Institute Pushes Liquid Biopsy Research Forward

Nov 30th, 2021 - The use of a routine blood test to assess and monitor patients with cancer, especially in a longitudinal manner, has long been the holy grail of cancer research. At the University of Arkansas for Medical Sciences (UAMS) Winthrop P. Rockefeller Cancer Institute, we have made big steps toward achieving that goal in the past 5 years. With the analysis of a simple blood test, also known as a liqui...

U.S. CDC urges Americans to avoid travel to Niger, Poland over COVID-19

Nov 30th, 2021 - WASHINGTON (Reuters) - The U.S. Centers for Disease Control and Prevention (CDC) on Tuesday advised Americans against travel to Niger, Papua New Guinea, Poland, and Trinidad and Tobago, citing COVID-19 concerns. On Saturday, the CDC added seven southern African countries to its “Level 4: Very High” classification after the White House announced new travel restrictions in response to the new Omi...

UPDATE 1-Telefonica offers redundancy to 3,000-plus staff, union says

Nov 30th, 2021 - (Adds detail, quote, context) MADRID, Nov 30 (Reuters) - Telefonica will offer voluntary redundancy to staff born in 1967 or earlier and with at least 15 years of employment at the company, the UGT union said on Tuesday, calculating that 3,261 employees would meet those conditions. Europe’s third-largest telecoms group and direct employer of 16,000 people in Spain would limit take-up of the off...

Role of Genomic Testing in mCRC

Nov 30th, 2021 - Tanios S. Bekaii-Saab, MD: The other thing that also has moved the needle quite a bit in our international practices is the availability of genomic testing. For those patients, especially those who present with later stages, the availability of genomic testing has facilitated decision-making in our part of the world. Almost every patient I see gets a next-generation sequencing [NGS] test either...

Overview of Colorectal Cancer

Nov 30th, 2021 - Tanios S. Bekaii-Saab, MD: Hello, and welcome to this OncLive® Insights® program titled My Treatment Approach: Metastatic Colorectal Cancer. My name is Tanios Bekaii-Saab. I’m at the Mayo Clinic. I lead the GI [gastrointestinal] cancer program and practice on our campus in Phoenix, Arizona. I’m pleased to be leading today’s discussion, along with 2 of my wonderful colleagues, Dr. Chiara Cremoli...

BioNTech CEO says current vaccine likely to protect against severe COVID from Omicron

Nov 30th, 2021 - FRANKFURT, Nov 30 (Reuters) - BioNTech and Pfizer’s established COVID-19 vaccine will likely offer strong protection against any severe disease from the new Omicron virus variant, BioNTech’s Chief Executive told Reuters, even as the biotech firm protectively makes a bolt for an adapted version of the shot. Lab tests are currently underway over the next two weeks analysing the blood of people wh...

Be cautious with HBV drug withdrawal
Jim Kling

Nov 30th, 2021 - More than half of chronic hepatitis B e antigen–negative patients who withdraw from nucleoside or nucleotide analogue therapy experienced relapse within 4 years, according to a new study that looked at patients from 11 centers in Europe, North America, and Asia. Grishma Hirode “We wanted to see if the patients stabilize after that year.

Vaccine under development by Spain's Hipra could be booster against variants, minister says

Nov 30th, 2021 - MADRID, Nov 30 (Reuters) - A COVID-19 vaccine currently under development by Spanish pharmaceutical firm Hipra could be effective as a booster against new variants of the virus, Spain’s Science Minister Diana Morant said on Tuesday. Spain’s medicines regulator two weeks ago authorised Hipra to carry out Phase II trials of its vaccine, which uses a recombinant protein like that of U.S. based dru...

Telefonica makes voluntary redundancy offer affecting up to 3,261 staff, UGT union says

Nov 30th, 2021 - MADRID, Nov 30 (Reuters) - Telefonica will offer voluntary redundancy to staff born in 1967 or earlier and with at least 15 years of employment at the company, the UGT union said on Tuesday, calculating that some 3,261 employees would meet those conditions. The company would limit takeup of the offer to 60% of staff in affected departments, UGT said. (Reporting by Clara-Laeila Laudette, editing...

Facebook says it disagrees with UK ruling on Giphy deal

Nov 30th, 2021 - LONDON, Nov 30 (Reuters) - Facebook-owner Meta said on Tuesday it disagreed with the British competition regulator’s ruling that it must sell animated images platform Giphy. “We disagree with this decision,” A Meta spokesperson said. “We are reviewing the decision and considering all options, including appeal.” (Reporting by Paul Sandle; Editing by Alistair Smout)

Britain regulator directs Facebook to sell GIF maker Giphy

Nov 30th, 2021 - Nov 30 (Reuters) - Britain’s competition regulator said on Tuesday it has directed Facebook owner Meta Platforms to sell animated images platform Giphy, after finding that the deal could harm social media users and UK advertisers. (Reporting by Yadarisa Shabong and Pushkala Aripaka in Bengaluru; Editing by Shounak Dasgupta)

National Grid, Scottish Power to pay $211 mln to customers after Western Link probe

Nov 30th, 2021 - Nov 30 (Reuters) - Electricity companies National Grid Electricity Transmission and Scottish Power Transmission have agreed to pay 158 million pounds ($211.12 million) to customers and British energy regulator Ofgem for a two-year delay to Western Link project. Ofgem said the companies have acknowledge the project, an undersea electrical link in the UK, was delivered later that scheduled. The r...

Threatened by Omicron, EU states urged to test more as some lag

Nov 30th, 2021 - BRUSSELS (Reuters) - The European Union’s health commissioner has urged governments to boost efforts to detect coronavirus mutations, as some lag behind even as the new Omicron variant is detected around the bloc. The variant first found in southern Africa has now been identified in several European countries, but it is hard to track its spread as various countries do not carry out sufficient g...

FTSE 100 eyes worst month in more than a year on Omicron hit

Nov 30th, 2021 - (For a Reuters live blog on U.S., UK and European stock markets, click LIVE/ or type LIVE/ in a news window) * FTSE 100 down 0.9%, FTSE 250 off 0.7% Nov 30 (Reuters) - UK’s blue-chip index fell on Tuesday, on course for its worst month in more than a year, as a warning by Moderna’s chief executive over the new Omicron coronavirus variant hammered pandemic-exposed sectors like banks and commodit...

BRIEF-Astrazeneca Says Lynparza Granted FDA Priority Review For Olympia