May 27th, 2022 - A study by Brazilian scientists points to the probable biological mechanism that modulates the accumulation of mutant mitochondrial DNA in cells during aging, especially in the liver. The mechanism is called autophagy, a process of cellular cleansing that destroys organelles, including mitochondria, and recycles their components. The findings resolve a paradigm in the field and raise a hypothes...

May 27th, 2022 - Jairo Kenupp Bastos first heard about the insect while visiting Canavieiras on the south coast of Bahia, a state in the Northeast of Brazil. “Local beekeepers told me about a tiny beetle that made holes in a plant called Dalbergia ecastaphyllum [Coinvine], a member of the pea family, and that the holes leaked a resin used by bees to make red propolis,” said Bastos, a professor of pharmacognosy ...

May 27th, 2022 - About The Study: The findings in this study of 2.6 million Chicago residents suggest that zip codes with low vaccination rates were associated with more deaths during the Alpha and Delta waves of COVID-19 and that inequitable vaccination coverage exacerbated existing racial and ethnic disparities in COVID-19 deaths. Authors: William F. Parker, M.D., Ph.D., of the University of Chicago, is the c...

May 27th, 2022 - Smart hearing aids that adapt to the individual needs of the user: for the last four years, the researchers of the Collaborative Research Centre (CRC) Hearing Acoustics have been working towards this goal. Now the German Research Foundation (DFG) has extended the funding of the project. Led by Prof. Dr. Volker Hohmann, a hearing researcher at the University of Oldenburg, the CRC will receive up...

May 27th, 2022 - Austin, TX— What children eat affects their lifelong health. But influencing their habits can be difficult, especially for underserved families with fewer resources. However, providing caregivers easy access to produce and flexible resources can lead to improvements in kids’ diets in a short time, according to a new study from researchers at Dell Medical School at The University of Texas at Aus...

May 27th, 2022 - May 27, 2022 – Plastic surgery residents face persistent barriers accessing affordable childcare, with high costs and a major impact on surgical training – with most of the burden falling on women residents, reports a paper in the June issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). Plastic and Reconstructive Surgery...

May 27th, 2022 - LA JOLLA, CA—Chemists at Scripps Research have unveiled a method for turning cheap and widely available chemicals known as dicarboxylic acids into potentially very valuable molecules called lactones. Lactone structures are common in biologically active natural molecules; they can be found, for example, in vitamin C and in the bacterial-derived antibiotic erythromycin. Chemists have long had tec...

May 27th, 2022 - Minneapolis, Minn. - Hennepin Healthcare Research Institute is testing an innovative way to help people quit smoking – by letting them bet on themselves and win real money. It’s part of a new game called QuitBet and it’s being funded by a National Institutes of Health (NIH) research grant administered by researchers at Hennepin Healthcare. Players commit to quit smoking over four weeks and bet ...

May 27th, 2022 - Researchers who analyzed language related to depression on social media during the pandemic say the data suggest people learned to cope as the waves wore on. University of Alberta researcher Alona Fyshe and her collaborators at the University of Western Ontario hypothesized that depression-related language would spike during each wave of COVID-19. But their study shows that wasn’t the case. “Th...

May 27th, 2022 - About The Study: Researchers found in this study of 22 high-income countries that cancer care spending in 2020 was not associated with age-standardized cancer mortality rates, and that although the United States spent more on cancer care than any other country, this expenditure was not associated with substantially lower cancer mortality rates. Authors: Cary P. Gross, M.D., of the Yale School o...

May 27th, 2022 - About The Study: Changes in catastrophic health care expenditures associated with chronic diseases in U.S. households from 2008 to 2018 were evaluated in this study. Authors: Young-Rock Hong, Ph.D., M.P.H., of the University of Florida in Gainesville, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1...

May 27th, 2022 - Autistic individuals are more likely to have chronic mental and physical health conditions, suggests new research from the University of Cambridge. Autistic individuals also report lower quality healthcare than others. These findings, published in Molecular Autism, have important implications for the healthcare and support of autistic individuals. Many studies indicate that autistic people are ...

May 27th, 2022 - Using a next generation sequencing analysis to examine human endogenous retrovirus (HERV) integration sites, researchers from Kumamoto University, the National Institute of Genetics (Japan), and the University of Michigan (USA) have discovered that these ancient retroviruses can undergo retrotransposition (DNA sequence insertion with RNA mediation) into iPS cells. The team believes that their d...

May 27th, 2022 - About The Study: The results of this analysis of 1,958 acute care hospitals and 702,000 patients suggest that hospitals that provide more registered nurse hours of care could likely decrease the likelihood of mortality in Medicare patients with sepsis. Authors: Jeannie P. Cimiotti, Ph.D., of Emory University in Atlanta, is the corresponding author. To access the embargoed study: Visit our For T...

May 27th, 2022 - Researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have identified a previously unrecognized form of hormone therapy-resistant prostate cancer, as well as a set of molecules that drive its growth. This discovery opens the door to the development of therapies that treat this specific disease. In the study, published May 27 in Science, the researchers examined the mo...

May 27th, 2022 - Administering medications to children poses unique challenges, especially in resource-limited countries with high infant and child mortality rates. Many drugs are solids or tablets, which are not easily swallowed by children and difficult to dose according to a child’s weight. While liquid and semi-solid alternatives exist for some drugs, many medications lack this option, or become unstable wi...

May 27th, 2022 - A study published in The Lancet Oncology suggests that a targeted radiation therapy is equitable to the current standard of care for patients whose lung cancer has metastasized to the brain. The work, led by researchers at St. Michael’s Hospital, a site of Unity Health Toronto, suggests that implementation of this targeted approach, which is known to result in fewer negative cognitive consequen...

May 27th, 2022 - Chromosomes undergo precise structural changes at a molecular level during the different phases of cell division. These changes occur at a high level of accuracy to prevent genome instability. Genome instability resulting from broken, missing, or rearranged chromosomes has been found to be the root cause of cell death, carcinogenesis, and congenital disorders. Studying genomic instability helps...

May 27th, 2022 - Philadelphia, May 27, 2022—Researchers with the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) will present a wide range of study results at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago and online June 3-7. The data include evaluations of new approaches to cancer treatment, control, care delivery, and health equity. The National Cancer Institute, part of the Na...

May 27th, 2022 - Nowadays doctors define and diagnose most diseases on the basis of symptoms. However, that does not necessarily mean that the illnesses of patients with similar symptoms will have identical causes or demonstrate the same molecular changes. In biomedicine, one often speaks of the molecular mechanisms of a disease. This refers to changes in the regulation of genes, proteins or metabolic pathways ...