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Low androgen in kidney recipients tied to diabetes
https://www.mdedge.com/endocrinology/article/247792/diabetes/low-androgen-kidney-recipients-tied-diabetes
Miriam E. Tucker

Oct 22nd, 2021 - Low androgen levels appear to be linked to the development of posttransplantation diabetes mellitus (PTDM) in male kidney transplant recipients, new research suggests. London_England/Thinkstock Among 243 men who did not have diabetes prior to undergoing kidney transplantation, levels of both dihydrotestosterone (DHT) and testosterone were inversely related to the risk for developing diabetes th.

How the pandemic prompted one clinic to embrace digital innovation
https://www.mdedge.com/dermatology/article/247790/business-medicine/how-pandemic-prompted-one-clinic-embrace-digital
Doug Brunk

Oct 22nd, 2021 - When the COVID-19 pandemic temporarily shuttered in-patient visits to a multispecialty practice in the San Francisco Bay Area in March of 2019, Olga Afanasiev, MD, PhD, and her colleagues saw an opportunity to create a new teledermatology workflow. Dr.

Keeler Family Farms Recalls Red, White, and Yellow Onions Due to Possible Health Risk
https://tools.cdc.gov/medialibrary/index.aspx#/media/id/428230

Keeler Family Farms of Deming, NM is voluntarily recalling red, yellow, and white onions shipped from July 1, 2021 through August 25, 2021 that were imported from Chihuahua, MX. The onions are recalled because they have the potential to be contaminated with Salmonella. Salmonella, is an organism t

Keeler Family Farms Recalls Red, White, and Yellow Onions Due to Possible Health Risk
https://tools.cdc.gov/medialibrary/index.aspx#/media/id/428229

Keeler Family Farms of Deming, NM is voluntarily recalling red, yellow, and white onions shipped from July 1, 2021 through August 25, 2021 that were imported from Chihuahua, MX. The onions are recalled because they have the potential to be contaminated with Salmonella. Salmonella, is an organism t

Exercise may help stall MS disability and progression
https://www.mdedge.com/neurology/article/247787/multiple-sclerosis/exercise-may-help-stall-ms-disability-and-progression
Jim Kling

Oct 22nd, 2021 - Though once regarded with suspicion, exercise as a therapy for multiple sclerosis (MS) has gained traction in recent years, and has the potential to counter the physical effects often seen among patients, as well as reduce risk of progression. Dr.

Explainer-Americans wonder: Which COVID-19 booster is best?
https://www.reuters.com/article/us-health-coronavirus-boosters-explainer/explainer-americans-wonder-which-covid-19-booster-is-best-idUSKBN2HC243

Oct 22nd, 2021 - CHICAGO (Reuters) - Americans this week were handed a big decision when it comes to getting a COVID-19 vaccine booster. The U.S. Centers for Disease Control and Prevention (CDC) on Thursday said individuals who qualify could choose a different vaccine from the one they received for their initial inoculation. For Americans asking how to choose, the following is what some experts advise: The CDC ...

TAS-102 Plus Bevacizumab Misses PFS End Point in Frontline Unresectable Metastatic CRC
https://www.onclive.com/view/tas-102-plus-bevacizumab-misses-pfs-end-point-in-frontline-unresectable-metastatic-crc

Oct 22nd, 2021 - The frontline combination of trifluridine/tipiracil (TAS-102; Lonsurf) and bevacizumab (Avastin) was not found to result in a significant improvement in progression-free survival (PFS) over capecitabine and bevacizumab in patients with unresectable metastatic colorectal cancer (mCRC) who are not eligible to receive intensive therapy, missing the primary end point of the phase 3 SOLSTICE trial (...

COVID Vaccine Recipients Also Less Likely to Die of Other Causes
https://www.medpagetoday.com/infectiousdisease/covid19vaccine/95220

Oct 22nd, 2021 - People who were vaccinated against COVID-19 were also less likely to die from non-COVID-19-related causes compared with unvaccinated people, researchers found. The adjusted relative risk of non-COVID-19 mortality ranged from 0.31 (95% CI 0.30-0.33) for those who received two doses of Moderna to 0.54 (95% CI 0.49-0.59) for Johnson & Johnson recipients, reported Stanley Xu, PhD, of Kaiser Permane...

Walmart, Walgreens U.S. stores roll out Moderna, J&J COVID-19 booster shots
https://www.reuters.com/article/health-coronavirus-boosters/update-4-walmart-walgreens-u-s-stores-roll-out-moderna-jj-covid-19-booster-shots-idUSL4N2RI3BC

Oct 22nd, 2021 - (Reuters) -Walgreens Boots Alliance Inc and Walmart Inc said on Friday their U.S. pharmacies started administering COVID-19 booster shots from Moderna Inc and Johnson & Johnson, in addition to previously authorized Pfizer-BioNTech booster. The Centers for Disease Control and Prevention (CDC) on Thursday recommended J&J and Moderna’s booster shots and said Americans can choose a different shot f...

Myeloma Drug Pulled From Market Just Months After Approval
https://www.medpagetoday.com/hematologyoncology/myeloma/95223

Oct 22nd, 2021 - Just months after FDA granted accelerated approval of its myeloma drug, Oncopeptides has pulled melphalan flufenamide (melflufen, Pepaxto) from the market. The decision followed an FDA hold on clinical trials of the drug after data from a confirmatory trial showed an increased mortality risk in patients treated with melflufen. The phase III OCEAN study compared melflufen plus dexamethasone and ...

NSCLC Incidence Declining, Except in Stage I Disease
https://www.medpagetoday.com/radiology/diagnosticradiology/95219

Oct 22nd, 2021 - The overall incidence of non-small cell lung cancer (NSCLC) decreased from 2010 to 2017, with the incidence of stage IV disease falling, and stage I disease rising, researchers determined. A cross-sectional epidemiological analysis showed that NSCLC incidence per 100,000 population declined from 46.4 to 40.9 during the study period. While the incidence of stage II, IIIA, and IIIB disease was st...

Pembrolizumab/Chemo Approved in Europe for Select Locally Recurrent Unresectable or Metastatic TNBC
https://www.onclive.com/view/pembrolizumab-chemo-approved-in-europe-for-select-locally-recurrent-unresectable-or-metastatic-tnbc

Oct 22nd, 2021 - The European Commission has approved pembrolizumab (Keytruda) plus chemotherapy for the frontline treatment of patients with locally recurrent unresectable or metastatic triple-negative breast cancer (TNBC) whose tumors have a PD-L1 expression combined positive score (CPS) of 10 or higher and who have not previously received chemotherapy for metastatic disease.1 The regulatory decision is ba...

Study: Chronic GI Disorders Surfaced Months After COVID
https://www.medpagetoday.com/gastroenterology/irritablebowelsyndrome/95218

Oct 22nd, 2021 - Four in 10 COVID-19 patients from disadvantaged communities developed new post-COVID gastrointestinal disorders, including functional dyspepsia (FD) and irritable bowel syndrome (IBS), researchers found in a retrospective study. In a survey of 200 individuals, 39.5% developed de novo post-COVID gastrointestinal disorders, with 58 reporting FD-like complaints, two reporting IBS-like complaints, ...

HCA Healthcare's labor pains cast shadow on upbeat quarter
https://www.reuters.com/article/hca-healthcare-results/update-4-hca-healthcares-labor-pains-cast-shadow-on-upbeat-quarter-idUSL4N2RI2TL

Oct 22nd, 2021 - (Reuters) -HCA Healthcare Inc on Friday cautioned higher labor costs that tarnished strong third quarter profits could linger for longer as the hospital operator battles a staff crunch, sending the company’s shares down. A nationwide shortage of healthcare workers amid fatigue from a prolonged COVID-19 pandemic has forced hospitals to shell out more to hire and retain nurses and other staff ami...

Burnout a Risk Factor for Suicidal Thoughts in Nurses
https://www.medpagetoday.com/nursing/nursing/95217

Oct 22nd, 2021 - Nurses experiencing burnout were twice as likely to have thoughts of suicide, and those with symptoms of depression were 11 times as likely to experience suicidal thoughts, a survey study found. Among more than 7,000 nurses surveyed from November to December 2017, a total of 5.5% experienced suicidal ideation, which is higher than rates of suicidal thoughts in the general population (4.3%), rep...

How can doctors help kids recover from COVID-19 school disruptions?
https://www.mdedge.com/pediatrics/article/247777/mental-health/how-can-doctors-help-kids-recover-covid-19-school
Jake Remaly

Oct 22nd, 2021 - Physicians may be able to help students get back on track after the pandemic derailed normal schooling, a developmental and behavioral pediatrician suggests. The disruptions especially affected vulnerable students, such as those with disabilities and those affected by poverty.

A Wealth of Therapeutic Advances in Lung Cancer Stress a Need for Early NGS Testing
https://www.onclive.com/view/a-wealth-of-therapeutic-advances-in-lung-cancer-stress-a-need-for-early-ngs-testing

Oct 22nd, 2021 - The overwhelming number of options for the treatment of patients with lung cancer underscores the importance of broad molecular testing up front to ensure patients receive optimal care, said Stephen V. Liu, MD. Our strategies [for managing lung cancer] are becoming more sophisticated and precise, but the first step of broad next-generation sequencing [NGS] is really the key. NGS is essential t...

FDA Approves Companion Diagnostic for Adjuvant Atezolizumab in Stage II to IIIA NSCLC
https://www.onclive.com/view/fda-approves-companion-diagnostic-for-adjuvant-atezolizumab-in-stage-ii-to-iiia-nsclc

Oct 22nd, 2021 - The FDA has approved the VENTANA PD-L1 (SP263) assay to assist in identifying which adult patients with stage II to IIIA non–small cell lung cancer (NSCLC) whose tumors have PD-L1 expression on 1% or more of tumor cells are eligible to receive adjuvant atezolizumab (Tecentriq) following surgery and platinum-based chemotherapy.1 Adjuvant atezolizumab was approved for use in this indication on O...

Too Many TAVR Centers Are Clustered Around Well-to-Do Communities
https://www.medpagetoday.com/cardiology/pci/95213

Oct 22nd, 2021 - The proliferation of transcatheter aortic valve replacement (TAVR) programs in the U.S. was largely limited to metropolitan areas and hospitals serving relatively affluent patients, a study found. Only 2% of the 583 hospitals with a TAVR program by the end of 2018 were not located in metropolitan areas, and there was only one rural center. Furthermore, half of new programs established in 2012 t...

Tissue Mapping Center for Cellular Senescence Launched at Yale Cancer Center to Study Human Lymphoid Organs
https://www.onclive.com/view/tissue-mapping-center-for-cellular-senescence-launched-at-yale-cancer-center-to-study-human-lymphoid-organs

Oct 22nd, 2021 - The National Institutes of Health (NIH) has awarded a grant to fund cellular senescence research in lymphoid organs at Yale Cancer Center. The five-year, $6.5 million grant will help generate multiscale molecular and cellular maps of cellular senescence in primary and secondary human lymphoid organs to improve our understanding of cellular senescence in development, aging, and disease, includin...