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Monoclonal gammopathy of undetermined significance (MGUS) - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/mgus/symptoms-causes/syc-20352362

Jul 22nd, 2021 - Overview Monoclonal gammopathy of undetermined significance (MGUS) is a condition in which an abnormal protein — known as monoclonal protein or M protein — is in your blood. This abnormal protein is formed within your bone marrow, the soft, blood-producing tissue that fills in the center of most of your bones. The disorder occurs most commonly in older men. MGUS usually causes no problems. But ...

Monoclonal gammopathy of undetermined significance (MGUS) - Care at Mayo Clinic - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/mgus/care-at-mayo-clinic/mac-20352370

Jul 22nd, 2021 - Monoclonal gammopathy of undetermined significance (MGUS) care at Mayo Clinic Your Mayo Clinic care team Mayo Clinic's MGUS teams are led by hematologists and include other specialists as needed, such as nephrologists in cases of kidney failure and cardiology in cases of amyloid involving the heart. Having all of this specialized expertise in a single place, focused on you, means that you're no...

Multiple myeloma - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/multiple-myeloma/symptoms-causes/syc-20353378

Jun 16th, 2021 - Overview Multiple myeloma is a cancer that forms in a type of white blood cell called a plasma cell. Healthy plasma cells help you fight infections by making antibodies that recognize and attack germs. In multiple myeloma, cancerous plasma cells accumulate in the bone marrow and crowd out healthy blood cells. Rather than produce helpful antibodies, the cancer cells produce abnormal proteins tha...

Multiple myeloma - Care at Mayo Clinic - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/multiple-myeloma/care-at-mayo-clinic/mac-20353386

Jun 16th, 2021 - Multiple myeloma care at Mayo Clinic Mayo Clinic specialists offer comprehensive care for people with multiple myeloma. Your Mayo Clinic care team Understanding and treating a family of blood cancers. Click here for an infographic to learn more At Mayo Clinic, you'll receive care from a team of doctors that works together to understand your goals and meet your needs as a whole person. There are...

Multiple myeloma - Diagnosis and treatment - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/multiple-myeloma/diagnosis-treatment/drc-20353383

Jun 16th, 2021 - Diagnosis Sometimes multiple myeloma is diagnosed when your doctor detects it accidentally during a blood test for some other condition. It can also be diagnosed if your doctor suspects you could have multiple myeloma based on your signs and symptoms. Tests and procedures used to diagnose multiple myeloma include: Blood tests. Laboratory analysis of your blood may reveal the M proteins produced...

Multiple myeloma - Outcomes & ratings - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/multiple-myeloma/outcomes/gnc-20514923

Jun 16th, 2021 - chis Kourelis, M.D., Hematology: Multiple myeloma is a blood cancer. It's the second most common blood cancer, but it's still a pretty rare cancer. It's 1 to 2% of all cancers, which comes down to about 35,000 new cases per year. Wilson I. Gonsalves, M.D., Hematology: A lot of what we know about myeloma and where it originates that entire thought process was initiated out here at the Mayo Clini...

Itchy skin (pruritus) - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/itchy-skin/symptoms-causes/syc-20355006

Jan 6th, 2021 - Overview Itchy skin is an uncomfortable, irritating sensation that makes you want to scratch. Also known as pruritus (proo-RIE-tus), itchy skin is often caused by dry skin. It's common in older adults, as skin tends to become drier with age. Depending on the cause of your itchiness, your skin may appear normal, red, rough or bumpy. Repeated scratching can cause raised thick areas of skin that m...

Vertebral tumor - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/vertebral-tumor/symptoms-causes/syc-20350123

Nov 14th, 2020 - Overview Spinal tumor consultation Nervous system Open pop-up dialog box Close Nervous system Nervous system The spinal cord is housed within a hollow chamber within the vertebrae (spinal canal). It extends from the base of the skull to the lower back. A vertebral tumor is a type of spinal tumor affecting the bones or vertebrae of the spine. Spinal tumors that begin within the spinal cord or th...

Bone metastasis - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/bone-metastasis/symptoms-causes/syc-20370191

Apr 21st, 2020 - Overview Bone metastasis occurs when cancer cells spread from their original site to a bone. Nearly all types of cancer can spread (metastasize) to the bones. But some types of cancer are particularly likely to spread to bone, including breast cancer and prostate cancer. Bone metastasis can occur in any bone but more commonly occurs in the spine, pelvis and thigh. Bone metastasis may be the fir...

Amyloidosis - Care at Mayo Clinic - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/amyloidosis/care-at-mayo-clinic/mac-20353187

Mar 14th, 2020 - Amyloidosis care at Mayo Clinic Your Mayo Clinic care team Amyloidosis can affect many parts of your body. At Mayo Clinic, hematologists work closely with doctors who specialize in pathology, transplantation and cancer, as well as in diseases of the brain and nervous system, heart, and kidneys. Together, they make your health care experience seamless. Advanced diagnosis and treatment Amyloidosi...

Cryoglobulinemia - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/cryoglobulinemia/symptoms-causes/syc-20371244

Dec 20th, 2019 - Overview Cryoglobulins are abnormal proteins in the blood. If you have cryoglobulinemia (kry-o-glob-u-lih-NEE-me-uh), these proteins may clump together at temperatures below 98.6 F (37 C). These gelatinous protein clumps can impede your blood circulation, which can damage your skin, joints, nerves and organs — particularly your kidneys and liver. Cryoglobulinemia care at Mayo Clinic Products & ...

POEMS Syndrome: Symptoms,
https://my.clevelandclinic.org/health/diseases/17985-poems-syndrome

Apr 16th, 2019 - Overview What is POEMS syndrome? POEMS syndrome is a blood disorder that affects multiple systems in the body. In this rare condition, abnormal plasma cells cause elevated levels of antibody proteins to accumulate in the blood. Having too many of these proteins in the blood can damage nerves and cause several organ systems to malfunction. POEMS syndrome is rare and can be life-threatening. It i...

Cryoglobulinemia: Symptoms, Causes, Te
https://my.clevelandclinic.org/health/diseases/13204-cryoglobulinemia

Feb 1st, 2019 - Overview What is cryoglobulinemia? Cryoglobulins are proteins found in the blood that precipitate (clump together) in the cold and may cause inflammation and organ damage. However, these proteins can also be present in low levels in the blood without causing any symptoms. When there are symptoms due to the cryoglobulins, the disease (usually a special rash) is called "cryoglobulinemia." Symptom...

Proteinuria: Causes, Symptoms,
https://my.clevelandclinic.org/health/diseases/16428-proteinuria

Jan 15th, 2019 - Overview What is proteinuria? Proteinuria is increased levels of protein in the urine. This condition can be a sign of kidney damage. Proteins – which help build muscle and bone, regulate the amount of fluid in blood, combat infection and repair tissue – should remain in the blood. If proteins enter the urine they ultimately leave the body, which isn’t healthy. How does protein get into urine? ...

Sarcoma Tumor: Type, Symptoms,
https://my.clevelandclinic.org/health/diseases/17934-sarcoma

Aug 20th, 2018 - Overview What is sarcoma? A sarcoma is a type of tumor that develops in connective tissue, such as bone, cartilage or muscle. Malignant sarcoma are very rare (1% of all adult malignancies and about 15% of childhood malignancies). Approximately 14,000 to 15,000 sarcomas are diagnosed in the United States every year (3,000 bone sarcomas and 11,000 to 12,000 soft tissue sarcomas). Sarcomas appear ...

Hypercalcemia: Causes, Symptoms, Diagnosis, Trea
https://my.clevelandclinic.org/health/diseases/14597-hypercalcemia

Jul 2nd, 2018 - Overview What is hypercalcemia? Hypercalcemia, or higher than normal level of calcium in your blood, is a fairly common finding. Blood tests, such as those drawn for an annual physical exam, today routinely check calcium levels. This allows physicians to detect abnormally high calcium levels early. Calcium is an important mineral in our bodies throughout our lifetime for bone growth, bone stren...

Monoclonal Gammopathy of Undetermined S
https://my.clevelandclinic.org/health/diseases/17744-monoclonal-gammopathy-of-undetermined-significance-mgus

Mar 8th, 2018 - Overview What is monoclonal gammopathy of undetermined significance (MGUS)? In monoclonal gammopathy of undetermined significance (MGUS), blood samples contain abnormal proteins called monoclonal proteins, or M proteins. Plasma cells in the bone marrow (the soft substance at the center of bones) produce M proteins. Normally, plasma cells produce antibodies that help your body fight infection. B...

Blood Disorders
https://medlineplus.gov/blooddisorders.html

- Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets. Blood disorders affect one or more parts of the blood and prevent your blood from doing its job. They can be acute or chronic. Many blood disorders...

Bone Marrow Transplantation
https://medlineplus.gov/bonemarrowtransplantation.html

- Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into red blood cells, which carry oxygen throughout the body, white blood cells, which fight infections, and platelets, which help the blood to clot. A bone marrow transplant is a procedure that replaces a person's faulty bone ma...

Multiple Myeloma
https://medlineplus.gov/multiplemyeloma.html

- Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. These cells are part of your immune system, which helps protect the body from germs and other harmful substances. In time, myeloma cells collect in the bone marrow and in the solid parts of bones. No one knows the exact causes of multiple myeloma, but it is more common in older people and African Americans. It...