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About 18,955 results

Low fetal age is not a contraindication for extracorporeal membranous oxygenation in CO...
https://doi.org/10.1111/jocs.16251
Journal of Cardiac Surgery; Zalle I, Barthelemy Y et. al.

Jan 22nd, 2022 - The coronavirus disease 2019 (COVID-19) causes a small proportion of patients to be admitted to intensive care units, where they sometimes require extracorporeal membrane oxygenation (ECMO). The literature on pregnant women with COVID-19 who require ECMO is sparse. We describe here the earliest-fetal-age pregnant patient with COVID-19 who underwent ECMO yet reported, who kept her child while un...

Quality of life and mortality among survivors of acute respiratory distress syndrome in...
https://doi.org/10.1007/s00540-022-03036-9 10.3390/ijms18010064 10.1001/jama.2016.0291 10.4187/respcare.04716 10.1007/s00134-006-0217-3 10.1001/jama.281.4.354 10.1007/s00134-003-1808-x 10.1164/rccm.200406-763OC 10.1378/chest.10-2438 10.1186/s12889-020-08943-8 10.1007/s00134-016-4321-8 10.1056/NEJMoa1011802 10.1164/rccm.201611-2327OC 10.1136/thoraxjnl-2017-210217 10.1136/thoraxjnl-2016-208560 10.1016/j.ijsu.2014.07.013 10.1001/jama.2012.5669 10.4046/trd.2017.80.2.105 10.1097/CCM.0000000000003015 10.1016/j.jcrc.2021.04.018 10.1186/s12889-020-10042-7 10.1186/s12931-021-01796-8 10.1186/s12913-020-05778-2 10.1007/s11136-021-02865-7 10.1016/j.chest.2016.06.032
Journal of Anesthesia; Choi HR, Song IA et. al.

Jan 22nd, 2022 - Worsening quality of life (QOL) is an important health issue in acute respiratory distress syndrome (ARDS) survivors. We aimed to investigate the prevalence of worsening QOL among ARDS survivors and their association with mortality. South Korean National Health Insurance database information for all adults admitted to intensive care units for ARDS from January 1, 2010 to December 31, 2018 who s...

Pearls & Oysters: Grisel Syndrome Presenting as Pseudodystonia: A Twist in the Neck.
https://doi.org/10.1212/WNL.0000000000200023
Neurology P DK, Cherian A

Jan 22nd, 2022 - Pseudodystonia is a term that describes abnormal postures, repetitive movements, or both, where clinical analysis, imaging, laboratory or electrophysiological investigations indicate that these movements are not consistent with dystonia. Grisel's syndrome (GS), characterised by rotatory subluxation of the atlantoaxial joint (AAJ) due to non-traumatic causes, is a cause of pseudodystonia. GS is ...

A Study of Brexanolone for Acute Respiratory Distress Syndrome Due to COVID-19
https://clinicaltrials.gov/ct2/show/NCT04537806

Jan 21st, 2022 - The purpose of this study is to evaluate the efficacy and safety of brexanolone in participants on ventilator support for acute respiratory distress syndrome (ARDS) due to COVID-19.

Pharmaco-immunomodulatory interventions for averting cytokine storm-linked disease seve...
https://doi.org/10.1007/s10787-021-00903-x 10.1016/s2352-3026(19)30156-5 10.1161/01.cir.93.4.810 10.1002/jmv.25964 10.1007/s11739-020-02600-z 10.1007/s11239-020-02162-z 10.1007/s00393-017-0292-6 10.1016/j.ijid.2020.11.149 10.1097/MAT.0000000000001173 10.1002/jmv.26062 10.3389/FIMMU.2020.01648 10.1056/NEJMoa2004500 10.1016/j.cell.2020.04.026 10.3389/fimmu.2020.01625 10.1016/j.jaci.2020.11.006 10.3389/FMED.2021.615333 10.1172/JCI141772 10.1016/j.jinf.2020.04.017 10.1016/j.jaci.2020.05.019 10.3389/fmed.2020.00466 10.1016/j.ejim.2020.05.009 10.15406/jaccoa.2021.13.00471 10.1073/pnas.2009017117 10.1016/S2665-9913(20)30127-2 10.1007/s11684-019-0714-8 10.1172/jci137244 10.1007/s15010-020-01476-7 10.1002/rmv.2141 10.1016/j.it.2006.11.002 10.1016/J.CYTOGFR.2020.06.001 10.3389/fimmu.2019.00119 10.1016/s2665-9913(21)00070-9 10.1038/s41375-020-01087-z 10.1016/j.ijid.2021.02.041 10.1016/S2665-9913(20)30170-3 10.1038/nrmicro.2016.81 10.3389/fimmu.2021.675678 10.1042/bj3500245 10.1016/j.blre.2020.100707 10.1098/RSOB.200160 10.1016/j.ijid.2020.05.026 10.1155/2021/8671713 10.4049/jimmunol.2001126 10.1016/j.chom.2020.04.009 10.1056/NEJMe2034982 10.1016/j.eclinm.2020.100553 10.1038/s41598-020-74001-3 10.1001/jamainternmed.2020.6252 10.1084/jem.20190945 10.1186/s12879-021-06119-2 10.1001/jamainternmed.2020.6820 10.1016/j.jaci.2020.05.008 10.1016/S2665-9913(20)30164-8 10.1111/jth.13911 10.1056/NEJMoa2100433 10.1002/phar.2438 10.1056/NEJMoa2031994 10.1186/S12985-020-01415-W 10.1080/14712598.2021.1847269 10.1016/s2352-3026(19)30207-8 10.1080/1744666x.2019.1629904 10.2174/1566524021666210803154250 10.7554/eLife.66125 10.1038/s41375-020-0891-0 10.1016/j.jaci.2020.07.009 10.1038/s41591-020-1038-6 10.1371/Journal.Pone.0023710 10.1016/j.ijid.2020.07.081 10.1007/s00134-020-06059-6 10.1136/bmjopen-2020-039951 10.1016/S2213-2600(21)00099-0 10.1002/jcp.1041650327 10.1186/s12950-020-0238-7 10.1002/jmv.25801 10.1172/jci138554 10.1016/s2213-2600(20)30267-8 10.1016/S0140-6736(20)30628-0 10.1016/s1359-6101(02)00045-x 10.1136/jitc-2020-001089 10.1002/art.41422 10.1002/rcr2.744 10.1182/blood-2012-10-460170 10.1016/j.jacc.2020.05.001 10.1016/j.cmi.2020.09.051 10.1016/j.jaci.2021.01.024 10.3389/FIMMU.2020.01446 10.1056/NEJMoa2021436 10.1136/bmj.n311 10.1002/ddr.21720 10.1001/jamainternmed.2020.6615 10.1007/s40121-021-00543-2 10.1016/j.jhep.2016.02.004 10.1146/annurev-immunol-041015-055649 10.1016/j.mehy.2020.110005 10.1371/journal.pone.0242400 10.1007/S10787-021-00860-5 10.1001/jamainternmed.2020.3313 10.1016/j.ijid.2020.07.023 10.15252/emmm.202012697 10.1056/NEJMoa2028836 10.1038/s41467-020-19509-y 10.1097/CCE.0000000000000203 10.1111/JTH.14817 10.1016/j.mayocp.2020.08.038 10.1101/2020.06.08.20125369 10.1016/s1473-3099(21)00202-4 10.1093/cid/ciaa879 10.1016/j.autrev.2020.102568 10.1016/j.ijid.2021.05.055 10.1186/S13054-020-03148-2 10.1016/s1470-2045(14)70319-5 10.1007/s00011-018-1188-x 10.1016/s0140-6736(20)30185-9 10.3201/eid1005.030640 10.1073/pnas.2005615117 10.1016/s2213-2600(20)30076-x 10.1038/s41422-021-00523-8 10.1016/J.JINF.2020.03.037 10.1016/j.thromres.2006.10.026 10.1016/j.bcp.2020.114296
Inflammopharmacology Kumar A, Sharma A et. al.

Jan 21st, 2022 - The year 2020 is characterised by the COVID-19 pandemic that has quelled more than half a million lives in recent months. We are still coping with the negative repercussions of COVID-19 pandemic in 2021, in which the 2nd wave in India resulted in a high fatality rate. Regardless of emergency vaccine approvals and subsequent meteoric global vaccination drives in some countries, hospitalisations ...

Prognostic findings for ICU admission in patients with COVID-19 pneumonia: baseline and...
https://doi.org/10.1007/s10140-021-02008-y 10.1016/S0140-6736(20)30183-5 10.1056/NEJMoa2002032 10.1590/0100-3984.2019.0049 10.1016/j.crad.2020.03.003 10.1016/j.jacc.2020.04.031 10.1016/j.chest.2020.06.025 10.1002/jmv.25910 10.1148/radiol.2020200527 10.1007/s00330-020-06801-0 10.1148/ryct.2020200034 10.1016/j.ejro.2020.100237 10.1016/j.ejrad.2020.109209 10.1007/s00330-020-06969-5 10.7150/thno.46569 10.1038/s41598-020-79183-4 10.1007/s00330-020-07033-y 10.5114/pjr.2020.98009 10.1016/j.ejrad.2020.109256 10.1259/bjro.20200016 10.1148/ryct.2020200130 10.4081/jphr.2021.2270 10.5152/dir.2020.20421 10.1038/s41598-020-78965-0 10.1097/RCT.0000000000001073 10.3906/sag-2009-49 10.3389/fpubh.2020.567672 10.3346/jkms.2020.35.e316 10.1155/2021/9941570 10.5152/dir.2020.20346 10.1093/cid/ciaa415 10.1016/j.metabol.2020.154244 10.1016/j.orcp.2020.07.005 10.1016/j.orcp.2020.12.002 10.4235/agmr.19.0001 10.1038/s41366-021-00907-1 10.1016/j.metabol.2020.154436 10.1186/s12933-021-01327-1 10.1016/j.ejrad.2020.109274 10.1371/journal.pone.0253433 10.1016/j.bone.2020.115790 10.1016/j.jocd.2021.07.007 10.17305/bjbms.2020.5466 10.1016/j.cmi.2020.07.030 10.1007/s11739-021-02795-9 10.1016/j.chest.2020.11.026 10.3390/diagnostics10110929 10.3390/diagnostics11091616 10.1016/j.rmed.2020.106271 10.1007/s10140-021-01903-8 10.1016/j.cegh.2020.11.006 10.1007/s00330-020-07623-w 10.21037/atm.2020.03.132 10.1038/s41467-020-17971-2 10.1007/s00330-020-07044-9 10.1148/radiol.2020202439 10.1007/s00330-020-07032-z 10.1148/radiol.2020200905 10.1002/mco2.14 10.1148/radiol.2020201491 10.3389/fbioe.2020.00898 10.1186/s12880-020-00521-z 10.1148/ryct.2020200075 10.1007/s00330-020-07013-2 10.1109/RBME.2020.2990959 10.3390/diagnostics11081317 10.1007/s11548-020-02299-5 10.3390/ijerph18062842 10.3348/kjr.2020.0994 10.7150/thno.45985 10.2196/24973 10.2196/21604 10.5152/dir.2020.20281 10.1016/j.acra.2020.09.004 10.3389/fpubh.2021.648360 10.1016/j.accpm.2020.10.014 10.1148/radiol.2020201433 10.5152/dir.2020.20407 10.7150/thno.46428 10.1101/2020.11.04.20225797 10.1016/j.media.2020.101844 10.1109/JBHI.2020.3036722 10.1038/s41598-021-95114-3 10.1371/journal.pone.0248957 10.1155/2020/5328267 10.1148/radiology.210.1.r99ja2629 10.1378/chest.107.4.1062 10.1148/radiol.2021203153 10.3389/fmed.2021.636298 10.1007/s10140-020-01869-z 10.1186/s12931-021-01625-y
Emergency Radiology; Laino ME, Ammirabile A et. al.

Jan 21st, 2022 - Infection with SARS-CoV-2 has dominated discussion and caused global healthcare and economic crisis over the past 18 months. Coronavirus disease 19 (COVID-19) causes mild-to-moderate symptoms in most individuals. However, rapid deterioration to severe disease with or without acute respiratory distress syndrome (ARDS) can occur within 1-2 weeks from the onset of symptoms in a proportion of patie...

Approach to echocardiography in ARDS patients in the prone position: A systematic review.
https://doi.org/10.1111/echo.15294
Echocardiography (Mount Kisco, N.Y.); Ajam M, Drake M et. al.

Jan 20th, 2022 - Echocardiography is commonly utilized in patients with acute respiratory distress syndrome (ARDS) for assessment of cardiac function, volume status, and the potential development of acute cor pulmonale. In severe ARDS, prone positioning is frequently used, which imposes technical challenges during transthoracic echocardiography (TTE) image acquisition. Moreover, prone positioning can affect car...

Risks and Benefits of Ultra-Lung-Protective Invasive Mechanical Ventilation Strategies ...
https://doi.org/10.1164/rccm.202110-2252CP
American Journal of Respiratory and Critical Care Medicine; Abrams D, Agerstrand C et. al.

Jan 20th, 2022 - Lung-protective ventilation strategies are the current standard of care for patients with acute respiratory distress syndrome (ARDS) in an effort to provide adequate ventilatory requirements while minimizing ventilator-induced lung injury. Some patients may benefit from ultra-lung-protective ventilation, a strategy that achieves lower airway pressures and tidal volumes than the current standard...

Clinical Profile and Short-Term Outcome of SARS-CoV-2-Infected Neonates from a Governme...
https://doi.org/10.1093/tropej/fmac002
Journal of Tropical Pediatrics; Banerjee M, Pal J et. al.

Jan 20th, 2022 - Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has led to a terrifying global pandemic. The presentations in neonates are varied with less case severity compared to adults. To describe the clinical and laboratory features and outcomes of neonates admitted with SARS-CoV-2 infection during the second surge of COVID-19 pandemic in a Government Medical College, West Bengal, India. It ...

Awake ECMO for COVID-19 Induced Acute Respiratory Distress Syndrome.
https://doi.org/10.1164/rccm.202105-1189LE
American Journal of Respiratory and Critical Care Medicine; Mang S, Reyher C et. al.

Jan 20th, 2022 - Awake ECMO for COVID-19 Induced Acute Respiratory Distress Syndrome.|2022|Mang S,Reyher C,Mutlak H,Natanov R,Lotz C,|

How common is ventilator-associated pneumonia after coronavirus disease 2019?
https://doi.org/10.1097/QCO.0000000000000817
Current Opinion in Infectious Diseases; Wicky PH, d'Humières C et. al.

Jan 20th, 2022 - The first studies on COVID-19 patients with acute respiratory distress syndrome (ARDS) described a high rate of secondary bacterial ventilator-associated pneumonia (VAP). The specificity of VAP diagnoses in these patients are reviewed, including their actual rate. Published studies described high rates of bacterial VAP among COVID-19 patients with ARDS, and these VAP episodes are usually severe...

Transfusion-Related Acute Lung Injury: 36 years of Progress (1985-2021).
https://doi.org/10.1513/AnnalsATS.202108-963CME
Annals of the American Thoracic Society; Toy P, Looney MR et. al.

Jan 20th, 2022 - The term transfusion-related acute lung injury (TRALI) was coined in 1985 to describe acute respiratory distress syndrome (ARDS) after transfusion, when another ARDS risk factor was absent; TRALI cases were mostly associated with donor leukocyte antibody. In 2001, plasma from multiparous donors was implicated in TRALI in a randomized controlled trial in Sweden. In 2003 and in many years thereaf...

Lung UltrasouNd Guided Surfactant Therapy in Preterm Infants (LUNG Study)
https://clinicaltrials.gov/ct2/show/NCT05198375

Jan 20th, 2022 - Background Management of neonatal respiratory distress syndrome (RDS) involves noninvasive respiratory supports, such as nasal continuous positive airway (nCPAP), and mechanical ventilation. On the other hand, exogenous surfactant administration is the other cornerstone for the treatment of RDS. Currently, the decision to administer surfactant in a non-invasively ventilated newborn is commonly ...

Study of Descartes-30 in Acute Respiratory Distress Syndrome
https://clinicaltrials.gov/ct2/show/NCT04524962

Jan 19th, 2022 - Emergency study to test the safety of Descartes-30 cells in patients with moderate-to-severe acute respiratory distress syndrome (ARDS) AND COVID-19

Early Lung Ultrasound Findings in Patients With COVID-19 Pneumonia: A Retrospective Mul...
https://doi.org/10.1002/jum.15944
Journal of Ultrasound in Medicine : Official Journal of T... Caroselli C, Blaivas M et. al.

Jan 19th, 2022 - Lung ultrasound (LUS) holds the promise of an accurate, radiation-free, and affordable diagnostic and monitoring tool in coronavirus disease 2019 (COVID-19) pneumonia. We sought to evaluate the usefulness of LUS in the diagnosis of patients with respiratory distress and suspicion of interstitial severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia, in comparison to other imagi...

Hospital-Acquired Pneumonia/Ventilator-Associated Pneumonia and Ventilator-Associated T...
https://doi.org/10.1055/s-0041-1740334
Seminars in Respiratory and Critical Care Medicine; Rouzé A, Nseir S

Jan 19th, 2022 - Although few studies evaluated the incidence of hospital-acquired pneumonia (HAP) or ventilator-associated tracheobronchitis in COVID-19 patients, several studies evaluated the incidence of ventilator-associated pneumonia (VAP) in these patients. Based on the results of a large multicenter European study, VAP incidence is higher in patients with SARS-CoV-2 pneumonia (36.1%), as compared with th...

Preclinical pharmacokinetics and safety of intravenous RTD-1.
https://doi.org/10.1128/aac.02125-21
Antimicrobial Agents and Chemotherapy; Park AYJ, Tran DQ et. al.

Jan 19th, 2022 - Severe illness caused by Coronavirus disease 2019 (COVID-19) is characterized by an overexuberant inflammatory response resulting in acute respiratory distress syndrome (ARDS) and progressive respiratory failure (1). Rhesus theta (θ) defensin-1 (RTD-1) is a macrocyclic host defense peptide exhibiting antimicrobial and immunomodulatory activities. RTD-1 treatment significantly improved survival ...

Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome
https://clinicaltrials.gov/ct2/show/NCT03793842

Jan 18th, 2022 - Doctors follow a standard ventilator management strategy when making adjustments to the breathing machine to optimize the amount of oxygen into the lungs. The purpose of this study is to assess whether the EIT (electrical impedance tomography) device can be an additional useful tool for ventilator management and identifying the ideal positive end-expiratory pressure (PEEP).

Effect of prone positioning on survival in adult patients receiving venovenous extracor...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762989
Intensive Care Medicine; Papazian L, Schmidt M et. al.

Jan 18th, 2022 - Previous studies support the potential efficacy of venovenous extracorporeal membrane oxygenation (vvECMO) for improving survival in severe acute respiratory distress syndrome (ARDS) cases. Prone positioning (PP) has been shown to improve the outcomes of moderate-to-severe ARDS patients. Few studies and no randomized controlled trials have evaluated the effect of PP performed in ECMO patients. ...

Strategies to minimize heterogeneity and optimize clinical trials in Acute Respiratory ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757652
EBioMedicine Subudhi S, Voutouri C et. al.

Jan 17th, 2022 - Mathematical modelling may aid in understanding the complex interactions between injury and immune response in critical illness. We utilize a system biology model of COVID-19 to analyze the effect of altering baseline patient characteristics on the outcome of immunomodulatory therapies. We create example parameter sets meant to mimic diverse patient types. For each patient type, we define the o...