Journal of Cardiac Surgery; Zalle I, Barthelemy Y et. al.
Jan 22nd, 2022 - The coronavirus disease 2019 (COVID-19) causes a small proportion of patients to be admitted to intensive care units, where they sometimes require extracorporeal membrane oxygenation (ECMO). The literature on pregnant women with COVID-19 who require ECMO is sparse. We describe here the earliest-fetal-age pregnant patient with COVID-19 who underwent ECMO yet reported, who kept her child while un...
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Journal of Anesthesia; Choi HR, Song IA et. al.
Jan 22nd, 2022 - Worsening quality of life (QOL) is an important health issue in acute respiratory distress syndrome (ARDS) survivors. We aimed to investigate the prevalence of worsening QOL among ARDS survivors and their association with mortality. South Korean National Health Insurance database information for all adults admitted to intensive care units for ARDS from January 1, 2010 to December 31, 2018 who s...
Neurology P DK, Cherian A
Jan 22nd, 2022 - Pseudodystonia is a term that describes abnormal postures, repetitive movements, or both, where clinical analysis, imaging, laboratory or electrophysiological investigations indicate that these movements are not consistent with dystonia. Grisel's syndrome (GS), characterised by rotatory subluxation of the atlantoaxial joint (AAJ) due to non-traumatic causes, is a cause of pseudodystonia. GS is ...
Jan 21st, 2022 - The purpose of this study is to evaluate the efficacy and safety of brexanolone in participants on ventilator support for acute respiratory distress syndrome (ARDS) due to COVID-19.
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Inflammopharmacology Kumar A, Sharma A et. al.
Jan 21st, 2022 - The year 2020 is characterised by the COVID-19 pandemic that has quelled more than half a million lives in recent months. We are still coping with the negative repercussions of COVID-19 pandemic in 2021, in which the 2nd wave in India resulted in a high fatality rate. Regardless of emergency vaccine approvals and subsequent meteoric global vaccination drives in some countries, hospitalisations ...
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Emergency Radiology; Laino ME, Ammirabile A et. al.
Jan 21st, 2022 - Infection with SARS-CoV-2 has dominated discussion and caused global healthcare and economic crisis over the past 18 months. Coronavirus disease 19 (COVID-19) causes mild-to-moderate symptoms in most individuals. However, rapid deterioration to severe disease with or without acute respiratory distress syndrome (ARDS) can occur within 1-2 weeks from the onset of symptoms in a proportion of patie...
Echocardiography (Mount Kisco, N.Y.); Ajam M, Drake M et. al.
Jan 20th, 2022 - Echocardiography is commonly utilized in patients with acute respiratory distress syndrome (ARDS) for assessment of cardiac function, volume status, and the potential development of acute cor pulmonale. In severe ARDS, prone positioning is frequently used, which imposes technical challenges during transthoracic echocardiography (TTE) image acquisition. Moreover, prone positioning can affect car...
American Journal of Respiratory and Critical Care Medicine; Abrams D, Agerstrand C et. al.
Jan 20th, 2022 - Lung-protective ventilation strategies are the current standard of care for patients with acute respiratory distress syndrome (ARDS) in an effort to provide adequate ventilatory requirements while minimizing ventilator-induced lung injury. Some patients may benefit from ultra-lung-protective ventilation, a strategy that achieves lower airway pressures and tidal volumes than the current standard...
Journal of Tropical Pediatrics; Banerjee M, Pal J et. al.
Jan 20th, 2022 - Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has led to a terrifying global pandemic. The presentations in neonates are varied with less case severity compared to adults. To describe the clinical and laboratory features and outcomes of neonates admitted with SARS-CoV-2 infection during the second surge of COVID-19 pandemic in a Government Medical College, West Bengal, India. It ...
American Journal of Respiratory and Critical Care Medicine; Mang S, Reyher C et. al.
Jan 20th, 2022 - Awake ECMO for COVID-19 Induced Acute Respiratory Distress Syndrome.|2022|Mang S,Reyher C,Mutlak H,Natanov R,Lotz C,|
Current Opinion in Infectious Diseases; Wicky PH, d'Humières C et. al.
Jan 20th, 2022 - The first studies on COVID-19 patients with acute respiratory distress syndrome (ARDS) described a high rate of secondary bacterial ventilator-associated pneumonia (VAP). The specificity of VAP diagnoses in these patients are reviewed, including their actual rate. Published studies described high rates of bacterial VAP among COVID-19 patients with ARDS, and these VAP episodes are usually severe...
Annals of the American Thoracic Society; Toy P, Looney MR et. al.
Jan 20th, 2022 - The term transfusion-related acute lung injury (TRALI) was coined in 1985 to describe acute respiratory distress syndrome (ARDS) after transfusion, when another ARDS risk factor was absent; TRALI cases were mostly associated with donor leukocyte antibody. In 2001, plasma from multiparous donors was implicated in TRALI in a randomized controlled trial in Sweden. In 2003 and in many years thereaf...
Jan 20th, 2022 - Background Management of neonatal respiratory distress syndrome (RDS) involves noninvasive respiratory supports, such as nasal continuous positive airway (nCPAP), and mechanical ventilation. On the other hand, exogenous surfactant administration is the other cornerstone for the treatment of RDS. Currently, the decision to administer surfactant in a non-invasively ventilated newborn is commonly ...
Jan 19th, 2022 - Emergency study to test the safety of Descartes-30 cells in patients with moderate-to-severe acute respiratory distress syndrome (ARDS) AND COVID-19
Journal of Ultrasound in Medicine : Official Journal of T... Caroselli C, Blaivas M et. al.
Jan 19th, 2022 - Lung ultrasound (LUS) holds the promise of an accurate, radiation-free, and affordable diagnostic and monitoring tool in coronavirus disease 2019 (COVID-19) pneumonia. We sought to evaluate the usefulness of LUS in the diagnosis of patients with respiratory distress and suspicion of interstitial severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia, in comparison to other imagi...
Seminars in Respiratory and Critical Care Medicine; Rouzé A, Nseir S
Jan 19th, 2022 - Although few studies evaluated the incidence of hospital-acquired pneumonia (HAP) or ventilator-associated tracheobronchitis in COVID-19 patients, several studies evaluated the incidence of ventilator-associated pneumonia (VAP) in these patients. Based on the results of a large multicenter European study, VAP incidence is higher in patients with SARS-CoV-2 pneumonia (36.1%), as compared with th...
Antimicrobial Agents and Chemotherapy; Park AYJ, Tran DQ et. al.
Jan 19th, 2022 - Severe illness caused by Coronavirus disease 2019 (COVID-19) is characterized by an overexuberant inflammatory response resulting in acute respiratory distress syndrome (ARDS) and progressive respiratory failure (1). Rhesus theta (θ) defensin-1 (RTD-1) is a macrocyclic host defense peptide exhibiting antimicrobial and immunomodulatory activities. RTD-1 treatment significantly improved survival ...
Jan 18th, 2022 - Doctors follow a standard ventilator management strategy when making adjustments to the breathing machine to optimize the amount of oxygen into the lungs. The purpose of this study is to assess whether the EIT (electrical impedance tomography) device can be an additional useful tool for ventilator management and identifying the ideal positive end-expiratory pressure (PEEP).
Intensive Care Medicine; Papazian L, Schmidt M et. al.
Jan 18th, 2022 - Previous studies support the potential efficacy of venovenous extracorporeal membrane oxygenation (vvECMO) for improving survival in severe acute respiratory distress syndrome (ARDS) cases. Prone positioning (PP) has been shown to improve the outcomes of moderate-to-severe ARDS patients. Few studies and no randomized controlled trials have evaluated the effect of PP performed in ECMO patients. ...
EBioMedicine Subudhi S, Voutouri C et. al.
Jan 17th, 2022 - Mathematical modelling may aid in understanding the complex interactions between injury and immune response in critical illness. We utilize a system biology model of COVID-19 to analyze the effect of altering baseline patient characteristics on the outcome of immunomodulatory therapies. We create example parameter sets meant to mimic diverse patient types. For each patient type, we define the o...