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About 27,525 results

The source of the Black Death in fourteenth-century central Eurasia.
https://doi.org/10.1038/s41586-022-04800-3 10.1162/jinh_a_01376 10.1038/nature10549 10.1017/S0022050717000092 10.1017/S1361491607002031 10.1073/pnas.1205750110 10.1038/s41467-019-12154-0 10.1371/journal.pone.0187230 10.3389/fmicb.2018.01106 10.1073/pnas.2009677117 10.1073/pnas.1812865115 10.17302/TMG.1-1.11 10.1163/18747167-12341321 10.1093/ahr/rhaa511 10.1038/nature14558 10.1186/s13059-019-1903-0 10.1073/pnas.1820447116 10.1146/annurev-genom-091416-035526 10.7554/eLife.12994 10.1016/S2666-5247(20)30176-2 10.1038/s41467-018-04550-9 10.1093/ve/vex042 10.1038/ng.705 10.1101/gr.251678.119 10.1016/j.celrep.2021.109278 10.1038/s41586-018-0094-2 10.1128/CMR.17.2.434-464.2004 10.1038/s41576-019-0119-1 10.1017/mdh.2021.3 10.1162/002219503322645439 10.4178/epih/e2015050 10.1073/pnas.1412887112 10.1086/711596 10.1038/srep43467 10.1101/gr.232397.117 10.1073/pnas.1314445110 10.1101/pdb.prot5448 10.1098/rstb.2013.0624 10.1093/nar/gkr771 10.1186/s13104-016-1900-2 10.1093/nar/gkv1189 10.1038/s41559-017-0446-6 10.1093/bioinformatics/btp352 10.1093/bioinformatics/btt193 10.1038/s41596-020-0338-0 10.1016/j.cub.2017.10.025 10.1038/nature16152 10.1073/pnas.1221359110 10.1038/nature14317 10.1186/s13059-016-0918-z 10.1073/pnas.1105107108 10.1371/journal.pcbi.1004957 10.1038/ng.806 10.1038/nature13591 10.1093/molbev/msw170 10.1128/genomeA.00847-17 10.1128/JB.186.15.5147-5152.2004 10.1093/bioinformatics/btu033 10.1093/bioinformatics/btq166 10.1016/0006-3207(92)91201-3 10.18637/jss.v053.i09 10.1093/molbev/msw054 10.1371/journal.pcbi.1006650 10.1093/molbev/msi103 10.1126/science.aaw8977 10.1038/s41598-020-66012-x 10.1126/science.abi5658 10.1038/s41559-020-1106-9 10.1186/s13059-020-02112-1 10.1073/pnas.1207965110 10.1038/nmeth.2109 10.1007/s11357-008-9053-4 10.1111/1749-4877.12511 10.1073/pnas.1715640115 10.1080/01621459.1995.10476572 10.1093/ve/vew007 10.1093/molbev/msaa163
Nature Spyrou MA, Musralina L et. al.

Jun 16th, 2022 - The origin of the medieval Black Death pandemic (AD 1346-1353) has been a topic of continuous investigation because of the pandemic's extensive demographic impact and long-lasting consequences1,2. Until now, the most debated archaeological evidence potentially associated with the pandemic's initiation derives from cemeteries located near Lake Issyk-Kul of modern-day Kyrgyzstan1,3-9. These sites...

Stone Age Yersinia pestis genomes shed light on the early evolution, diversity, and eco...
https://doi.org/10.1073/pnas.2116722119
Proceedings of the National Academy of Sciences of the Un... Andrades Valtueña A, Neumann GU et. al.

Apr 13th, 2022 - The bacterial pathogen Yersinia pestis gave rise to devastating outbreaks throughout human history, and ancient DNA evidence has shown it afflicted human populations as far back as the Neolithic. Y. pestis genomes recovered from the Eurasian Late Neolithic/Early Bronze Age (LNBA) period have uncovered key evolutionary steps that led to its emergence from a Yersinia pseudotuberculosis-like proge...

The International Association for the Study of Lung Cancer Thymic Epithelial Tumor Stag...
https://doi.org/10.1016/j.jtho.2022.03.005
Journal of Thoracic Oncology : Official Publication of Th... Ruffini E, Rami-Porta R et. al.

Mar 25th, 2022 - Thymic epithelial tumors are presently staged using a consistent TNM classification developed by the International Association for the Study of Lung Cancer (IASLC) and approved by the Union for International Cancer Control and the American Joint Committee on Cancer. The stage classification is incorporated in the eight edition of the TNM classification of thoracic malignancies. The IASLC Stagin...

Detection of SARS-CoV-2 and the L452R spike mutation using reverse transcription loop-m...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936440
PloS One; Iijima T, Ando S et. al.

Mar 22nd, 2022 - The new coronavirus infection (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be fatal, and several variants of SARS-CoV-2 with mutations of the receptor-binding domain (RBD) have increased avidity for human cell receptors. A single missense mutation of U to G at nucleotide position 1355 (U1355G) in the spike (S) gene changes leucine to arginine (L452R) in ...

Professional practice for COVID-19 risk reduction among health care workers: A cross-se...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936447
PloS One; Wilson S, Mouet A et. al.

Mar 22nd, 2022 - Health care workers (HCWs) are particularly exposed to COVID-19 and therefore it is important to study preventive measures in this population. To investigate socio-demographic factors and professional practice associated with the risk of COVID-19 among HCWs in health establishments in Normandy, France. A cross-sectional and 3 case-control studies using bootstrap methods were conducted in order ...

Update from the 5th Edition of the World Health Organization Classification of Head and...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018914
Head and Neck Pathology; Muller S, Tilakaratne WM

Mar 22nd, 2022 - The fifth chapter of the upcoming fifth edition of the 2022 World Health Organization Classification of Tumours of the Head and Neck titled Tumours of the oral cavity and mobile tongue, has had some modifications from the 2017 fourth edition. A new section "Non-neoplastic Lesions", introduces two new entries: necrotizing sialometaplasia and melanoacanthoma. The combined Oral potentially maligna...

SARS-CoV-2 Evolution: On the Sudden Appearance of the Omicron Variant.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006888
Journal of Virology; Berkhout B, Herrera-Carrillo E

Mar 17th, 2022 - The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads rapidly and harbors many mutations in the spike protein, but the origin of this virus variant remains unclear. We address the role of unusual virus evolution mechanisms such as hypermutation, out-of-frame reading, and recombination. Rather, regular Darwinian evolution, that is, the repeated selection of ...

Surveillance of SARS-CoV-2 virus circulation using Acute Respiratory Infections sentine...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920273
PloS One; Jané M, Martínez A et. al.

Mar 15th, 2022 - In the context of COVID-19 pandemic in Catalonia (Spain), the present study analyses respiratory samples collected by the primary care network using Acute Respiratory Infections Sentinel Surveillance System (PIDIRAC) during the 2019-2020 season to complement the pandemic surveillance system in place to detect SARS-CoV-2. The aim of the study is to describe whether SARS-CoV-2 was circulating bef...

OPTN/SRTR 2020 Annual Data Report: DOD.
https://doi.org/10.1111/ajt.16976
American Journal of Transplantation : Official Journal Of... Israni AK, Zaun D et. al.

Mar 11th, 2022 - SRTR uses data collected by OPTN to calculate metrics such as donation rate, organ yield, and rate of organs recovered for transplant but not transplanted. In 2020, there were 12,588 deceased donors, an increase from 11,870 in 2019; this number has been increasing since 2010. The number of deceased donor transplants increased to 33,303 in 2020, from 32,313 in 2019; this number has been increasi...

Antimicrobial resistance (AMR) in COVID-19 patients: a systematic review and meta-analy...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8899460
Antimicrobial Resistance and Infection Control; Kariyawasam RM, Julien DA et. al.

Mar 9th, 2022 - Pneumonia from SARS-CoV-2 is difficult to distinguish from other viral and bacterial etiologies. Broad-spectrum antimicrobials are frequently prescribed to patients hospitalized with COVID-19 which potentially acts as a catalyst for the development of antimicrobial resistance (AMR). We conducted a systematic review and meta-analysis during the first 18 months of the pandemic to quantify the pre...

Comparative analysis of alignment-free genome clustering and whole genome alignment-bas...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903263
PloS One; Kirichenko AD, Poroshina AA et. al.

Mar 9th, 2022 - The SARS-CoV-2 is the third coronavirus in addition to SARS-CoV and MERS-CoV that causes severe respiratory syndrome in humans. All of them likely crossed the interspecific barrier between animals and humans and are of zoonotic origin, respectively. The origin and evolution of viruses and their phylogenetic relationships are of great importance for study of their pathogenicity and development o...

Planned vaginal and planned cesarean delivery outcomes in pregnancies complicated with ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892757
BMC Pregnancy and Childbirth; Kruit H, Mertsalmi S et. al.

Mar 4th, 2022 - Finland has the world's highest incidence of 62.5/100000 of diabetes mellitus type 1 (DM1) with approximately 400 (1%) DM1 pregnancies annually. Pregnancies complicated by DM1 are accompanied with increased risk for perinatal morbidity and mortality. Timing and mode of delivery are based on the risk of complications, yet the data on labor induction is limited. The aim of this study was to compa...

Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866425
Nature Communications; Aggarwal D, Page AJ et. al.

Feb 25th, 2022 - Mitigation of SARS-CoV-2 transmission from international travel is a priority. We evaluated the effectiveness of travellers being required to quarantine for 14-days on return to England in Summer 2020. We identified 4,207 travel-related SARS-CoV-2 cases and their contacts, and identified 827 associated SARS-CoV-2 genomes. Overall, quarantine was associated with a lower rate of contacts, and the...

Identification of a biological form in the Anopheles stephensi laboratory colony using ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863247
PloS One; Khan J, Gholizadeh S et. al.

Feb 23rd, 2022 - Anopheles stephensi Listen (1901) is a major vector of malaria in Asia and has recently been found in some regions of Africa. The An. stepehnsi species complex is suspected to have three sibling species: type, intermediate, and mysorensis, each with its own vector competence to the malaria parasite and ecology. To identify the members of the species complex in our An. stephensi insectary colony...

Pulmonary "Inflammatory Leiomyosarcomas" Are Indolent Tumors With Diploid Genomes and N...
https://doi.org/10.1097/PAS.0000000000001804
The American Journal of Surgical Pathology; Kao YC, Kuo CT et. al.

Feb 18th, 2022 - Inflammatory leiomyosarcoma is a rare myogenic tumor with striking inflammatory infiltrates and a specific genomic pattern of near-haploidization despite exception(s). Recent studies demonstrated that inflammatory leiomyosarcoma shares substantially overlapping features with histiocyte-rich rhabdomyoblastic tumor, including expression of rhabdomyoblastic markers such as myogenin, MyoD1, and PAX...

Gut bacterial dysbiosis and instability is associated with the onset of complications a...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855857
Gut Microbes; Schult D, Reitmeier S et. al.

Feb 18th, 2022 - There is a growing debate about the involvement of the gut microbiome in COVID-19, although it is not conclusively understood whether the microbiome has an impact on COVID-19, or vice versa, especially as analysis of amplicon data in hospitalized patients requires sophisticated cohort recruitment and integration of clinical parameters. Here, we analyzed fecal and saliva samples from SARS-CoV-2 ...

Persistence of Schistosoma haematobium transmission among school children and its impli...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846507
PloS One; Mushi V, Zacharia A et. al.

Feb 16th, 2022 - Despite twelve rounds of school-based preventive chemotherapy for schistosomiasis in endemic areas of Tanzania such as Mtama district, Lindi: the burden of Schistosoma haematobium infection has remained highly conceivable due to re-infections. The factors associated with continuity of S.haematobium transmission in Mtama district, Lindi have not been fully established. This study investigated th...

The variable presence of Leptospira in the environment; an epidemiological explanation ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846531
PloS One; Warnasekara J, Srimantha S et. al.

Feb 16th, 2022 - Human leptospirosis involves the classic epidemiological triad (agent, host and environment); hence the investigations should include the knowledge on Leptospira within the animals and the environment. The objectives of this study are to explore the abundance of Leptospira in different climate zones of Sri Lanka and to describe the presence of Leptospira in the same water source at serial time ...

Whole-genome sequencing of Kaposi sarcoma-associated herpesvirus (KSHV/HHV8) reveals ev...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915436
Virology Moorad R, Juarez A et. al.

Feb 14th, 2022 - Kaposi sarcoma (KS)-associated herpesvirus (KSHV/HHV-8) was first sequenced from the body cavity (BC) lymphoma cell line, BC-1, in 1996. Few other KSHV genomes have been reported. Our knowledge of sequence variation for this virus remains spotty. This study reports additional genomes from historical US patient samples and from African KS biopsies. It describes an assay that spans regions of the...

Reciprocal circulation pattern of SARS-CoV-2 and influenza viruses during the influenza...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576129
Epidemiology and Infection; Heinzinger S, Eberle U et. al.

Feb 11th, 2022 - The corona virus disease-2019 (COVID-19) pandemic began in Wuhan, China, and quickly spread around the world. The pandemic overlapped with two consecutive influenza seasons (2019/2020 and 2020/2021). This provided the opportunity to study community circulation of influenza viruses and severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) in outpatients with acute respiratory infections d...