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About 277,350 results

Comparison of the sixth, seventh, and eighth editions of the American Joint Committee o...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483861
Medicine Chen MW, Yen HH

Oct 2nd, 2021 - In 2018, the eighth edition of the American Joint Committee on Cancer Tumor-Node-Metastasis classification and staging system was implemented. Few reports were made comparing the performance of different editions of the American Joint Committee on Cancer (AJCC) system. Therefore, this study aimed to examine the prognostic predictability from the sixth to the eighth editions of the AJCC staging ...

Closest known relatives of virus behind COVID-19 found in Laos.
https://doi.org/10.1038/d41586-021-02596-2 10.1038/s41467-021-21240-1 10.1016/j.cell.2021.06.008 10.1038/s41586-020-2012-7 10.1038/s41564-020-0771-4
Nature Mallapaty S

Sep 26th, 2021 - Closest known relatives of virus behind COVID-19 found in Laos.|2021|Mallapaty S,|classification,genetics,isolation & purification,transmission,virology,virology,metabolism,classification,genetics,isolation & purification,chemistry,genetics,metabolism,transmission,virology,

Analysis of changes in the volume of edema around brain contusions and the influencing ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462588
Medicine Liu HB, Xu WM et. al.

Sep 25th, 2021 - Traumatic brain injury (TBI), a common neurosurgical condition, has well-known treatment guidelines. However, the mechanisms underlying the varying severity of brain edema secondary to TBI are largely unknown, leading to controversial treatments.This study seeks to measure edema volumes around brain contusions in different regions, analyze factors related to differences in edema volume and prov...

Molecular conversations.
https://doi.org/10.1038/s41589-021-00891-7
Nature Chemical Biology;

Sep 24th, 2021 - Molecular conversations.|2021||classification,classification,physiology,classification,

Industry and workplace characteristics associated with the downloading of a COVID-19 co...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454017
Environmental Health and Preventive Medicine; Ishimaru T, Ibayashi K et. al.

Sep 23rd, 2021 - To combat coronavirus disease 2019 (COVID-19), many countries have used contact tracing apps, including Japan's voluntary-use contact-confirming application (COCOA). The current study aimed to identify industry and workplace characteristics associated with the downloading of this COVID-19 contact tracing app. This cross-sectional study of full-time workers used an online survey. Multiple logist...

Leveraging the Cell Ontology to classify unseen cell types.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455606
Nature Communications; Wang S, Pisco AO et. al.

Sep 23rd, 2021 - Single cell technologies are rapidly generating large amounts of data that enables us to understand biological systems at single-cell resolution. However, joint analysis of datasets generated by independent labs remains challenging due to a lack of consistent terminology to describe cell types. Here, we present OnClass, an algorithm and accompanying software for automatically classifying cells ...

Congruent trophic pathways underpin global coral reef food webs.
https://doi.org/10.1073/pnas.2100966118
Proceedings of the National Academy of Sciences of the Un... Pozas-Schacre C, Casey JM et. al.

Sep 22nd, 2021 - Ecological interactions uphold ecosystem structure and functioning. However, as species richness increases, the number of possible interactions rises exponentially. More than 6,000 species of coral reef fishes exist across the world's tropical oceans, resulting in an almost innumerable array of possible trophic interactions. Distilling general patterns in these interactions across different bio...

Altered gut microbial metabolites could mediate the effects of risk factors in Covid-19.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995004
Reviews in Medical Virology; Chen J, Hall S et. al.

Sep 22nd, 2021 - Coronavirus disease 2019 (Covid-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, is now pandemic. While most Covid-19 patients will experience mild symptoms, a small proportion will develop severe disease, which could be fatal. Clinically, Covid-19 patients manifest fever with dry cough, fatigue and dyspnoea, and in severe cases develop into acute respirato...

Influence of Left Ventricular Function on the "Aortic Regurgitation Index" Proposed for...
https://doi.org/10.1536/ihj.21-028
International Heart Journal; Kanzaki H, Amaki M et. al.

Sep 22nd, 2021 - The aortic regurgitation (AR) index, proposed as an objective indicator of postprocedural AR, decreases in proportion to AR severity, besides reportedly providing additional prognostic information. Meanwhile, left ventricular (LV) function has also been considered an essential prognostic factor. This study aimed to clarify whether LV function affected the AR index using cardiac catheterization ...

Treatment of B1 Distal Periprosthetic Femur Fractures.
https://doi.org/10.1016/j.ocl.2021.05.001
The Orthopedic Clinics of North America; Sheridan GA, Sepehri A et. al.

Sep 21st, 2021 - The burden of periprosthetic distal femoral fractures is projected to increase accordingly with the increase in total knee arthroplasties (TKAs) performed globally in the future. Less invasive plating and intramedullary (IM) nailing techniques still seem to provide similar outcomes based on current literature. Double-plating and combination techniques may prove to be beneficial in the future pe...

Classification and Management of Periprosthetic Patella Fractures.
https://doi.org/10.1016/j.ocl.2021.05.003
The Orthopedic Clinics of North America; Deans J, Scuderi GR

Sep 21st, 2021 - Complications related to the extensor mechanism and patellofemoral joint continue to be the most common cause of pain and indication for surgical revision following total knee arthroplasty. Numerous risk factors related to the patient, implant, and technical performance of the procedure have been identified. The Ortiguera and Berry classification system is widely used for the systematic classif...

The Syndesmosis, Part I: Anatomy, Injury Mechanism, Classification, and Diagnosis.
https://doi.org/10.1016/j.ocl.2021.05.010
The Orthopedic Clinics of North America; Bejarano-Pineda L, Guss D et. al.

Sep 21st, 2021 - Ankle fractures are common injuries to the lower extremity with approximately 20% sustaining a concomitant injury to the syndesmosis. Although the deltoid ligament is not formally included in the syndesmotic complex, it plays an important role in the mortise stability. Therefore, its integrity should be always evaluated when syndesmotic injury is suspected. Given the anatomic variability of the...

Thoracolumbar Spine Trauma.
https://doi.org/10.1016/j.ocl.2021.05.014
The Orthopedic Clinics of North America; Waddell WH, Gupta R et. al.

Sep 21st, 2021 - Thoracolumbar spine trauma can result in potentially life-threatening consequences and requires careful management to ensure good outcomes. The purpose of this chapter is to discuss the anatomy, diagnostic tools, non-operative, and operative treatments important when addressing thoracolumbar trauma.

Neofunctionalization of an ancient domain allows parasites to avoid intraspecific compe...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446075
Nature Communications; Chen J, Fang G et. al.

Sep 18th, 2021 - Intraspecific competition is a major force in mediating population dynamics, fuelling adaptation, and potentially leading to evolutionary diversification. Among the evolutionary arms races between parasites, one of the most fundamental and intriguing behavioural adaptations and counter-adaptations are superparasitism and superparasitism avoidance. However, the underlying mechanisms and ecologic...

Evolution and dispersal of snakes across the Cretaceous-Paleogene mass extinction.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440539
Nature Communications; Klein CG, Pisani D et. al.

Sep 16th, 2021 - Mass extinctions have repeatedly shaped global biodiversity. The Cretaceous-Paleogene (K-Pg) mass extinction caused the demise of numerous vertebrate groups, and its aftermath saw the rapid diversification of surviving mammals, birds, frogs, and teleost fishes. However, the effects of the K-Pg extinction on the evolution of snakes-a major clade of predators comprising over 3,700 living species-...

Designing efficient genetic code expansion in Bacillus subtilis to gain biological insi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8440579
Nature Communications; Stork DA, Squyres GR et. al.

Sep 16th, 2021 - Bacillus subtilis is a model gram-positive bacterium, commonly used to explore questions across bacterial cell biology and for industrial uses. To enable greater understanding and control of proteins in B. subtilis, here we report broad and efficient genetic code expansion in B. subtilis by incorporating 20 distinct non-standard amino acids within proteins using 3 different families of genetic ...

Phylogenetic conservatism drives nutrient dynamics of coral reef fishes.
https://doi.org/10.1038/s41467-021-25528-0 10.2307/1310789 10.1146/annurev.ecolsys.33.010802.150519 10.1007/s10021-013-9715-7 10.1073/pnas.1502549112 10.1111/gcb.13625 10.1034/j.1600-0706.2002.990201.x 10.1038/nature11148 10.1126/science.1064088 10.1890/04-0922 10.1073/pnas.0608148104 10.1038/s41559-019-1070-4 10.1111/j.1461-0248.2010.01515.x 10.1086/284467 10.1038/s41467-018-06199-w 10.1111/1365-2435.13197 10.1002/ecy.3100 10.1038/s41598-020-67881-y 10.1073/pnas.1420819112 10.2307/1943285 10.1016/0169-5347(88)90117-6 10.2307/1936746 10.1038/ncomms12461 10.1111/gcb.12566 10.1890/14-0331.1 10.1007/BF00336775 10.1016/j.apgeochem.2018.11.020 10.1016/S0070-4571(04)80023-2 10.4319/lo.2010.55.6.2660 10.3354/meps219109 10.1111/j.1095-8649.2006.01280.x 10.1046/j.1461-0248.2002.00314.x 10.1002/ecy.1582 10.1002/ecs2.1452 10.1890/0012-9658(2000)081[0127:CNAPSO]2.0.CO;2 10.1073/pnas.97.11.5693 10.1111/j.1461-0248.2005.00791.x 10.2307/2265529 10.1016/S0025-326X(00)00104-1 10.1371/journal.pone.0011916 10.1890/0012-9658(2000)081[1701:EOGSOP]2.0.CO;2 10.4319/lom.2009.7.1 10.1899/0887-3593(2007)26[167:ITFAMM]2.0.CO;2 10.1073/pnas.1317625111 10.1038/s41586-018-0273-1 10.1111/2041-210X.13182 10.1111/j.2041-210X.2011.00169.x 10.1111/j.1420-9101.2009.01915.x 10.18637/jss.v033.i02 10.1111/j.2041-210x.2012.00261.x 10.1093/bioinformatics/btq166 10.1111/j.1365-2656.2011.01806.x
Nature Communications; Allgeier JE, Weeks BC et. al.

Sep 16th, 2021 - The relative importance of evolutionary history and ecology for traits that drive ecosystem processes is poorly understood. Consumers are essential drivers of nutrient cycling on coral reefs, and thus ecosystem productivity. We use nine consumer "chemical traits" associated with nutrient cycling, collected from 1,572 individual coral reef fishes (178 species spanning 41 families) in two biogeog...

Multi-intervention integrated deworming strategy for sustained control of soil-transmit...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434715
Infectious Diseases of Poverty; Mao FZ, Chen YY et. al.

Sep 12th, 2021 - Soil-transmitted helminths (STH) infections still present a global health problem. Mass drug administration (MDA) is a widely applied strategy to reduce morbidity and mortality caused by STH. Yet, this approach has some shortcomings. In this study, we analyzed the impact of a multi-intervention integrated deworming approach including MDA, health education (HE), and environmental sanitation impr...

The role of Magnetic Resonance Images (MRIs) in coping for patients with brain tumours ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431927
BMC Cancer; Tyldesley-Marshall N, Greenfield S et. al.

Sep 12th, 2021 - When children and young people (CYP) are diagnosed with a brain tumour, Magnetic Resonance Imaging (MRI) is key to the clinical management of this condition. This can produce hundreds, and often thousands, of Magnetic Resonance Images (MRIs). Semi-structured interviews were undertaken with 14 families (15 parents and 8 patients), and analysed using Grounded Theory. Analysis was supported by the...

Genomics, social media and mobile phone data enable mapping of SARS-CoV-2 lineages to i...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8478645
Nature Microbiology; Cowley LA, Afrad MH et. al.

Sep 10th, 2021 - Genomics, combined with population mobility data, used to map importation and spatial spread of SARS-CoV-2 in high-income countries has enabled the implementation of local control measures. Here, to track the spread of SARS-CoV-2 lineages in Bangladesh at the national level, we analysed outbreak trajectory and variant emergence using genomics, Facebook 'Data for Good' and data from three mobile...