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Abid on Optimizing COVID-19 Vaccines in CAR T-Cell Therapy Recipients
https://www.onclive.com/view/abid-on-optimizing-covid-19-vaccines-in-car-t-cell-therapy-recipients

Nov 22nd, 2021 - Welcome to OncLive On Air®! I’m your host today, Kristi Rosa. OncLive On Air® is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive® covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions. In today’s...

“It Is a Tiger That Devours Me, But I Am the Tiger”
https://wwwnc.cdc.gov/eid/article/27/12/ac-2712_article

Nov 21st, 2021 - Franz Marc (1880−1916), The Tiger, 1912. Oil on canvas. 43.9 in x 40.0 in/111.7 cm x 101.8 cm. Städtische Galerie im Lenbachhaus and Kunstbau, Munich, Germany. Image source: Art Resource, New York, New York, USA. On March 11, 2020, the World Health Organization declared COVID-19 to be a pandemic. Shortly thereafter, reports of animals becoming infected with SARS-CoV-2 appeared. Although the pan...

SARS-CoV-2–Specific Antibodies in Domestic Cats during First COVID-19 Wave, Europe
https://wwwnc.cdc.gov/eid/article/27/12/21-1252_article

Nov 19th, 2021 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the ongoing coronavirus disease (COVID-19) pandemic, causes high rates of illness and death among humans. SARS-CoV-2 is a newly recognized member of the genus Betacoronavirus, family Coronaviridae, that infects humans. An early serosurvey among domestic cats in Wuhan, China, during January–March 2020 reported 14.7% serop...

Surface‒Aerosol Stability and Pathogenicity of Diverse Middle East Respiratory Syndrome Coronavirus Strains, 2012‒2018
https://wwwnc.cdc.gov/eid/article/27/12/21-0344_article

Nov 19th, 2021 - Middle East respiratory syndrome coronavirus (MERS-CoV) was detected during 2012 and continues to cause outbreaks as a result of frequent spillover from dromedary camels to humans. Human infection with MERS-CoV has a mortality rate of ≈35%, and the virus has spread to 27 countries (1). Approximately 41% of human MERS-CoV infections in Saudi Arabia are primary, resulting from direct camel-to-hum...

Nationwide Study on Susceptibility of Patients on Dialysis to COVID-19
https://www.medscape.com/viewarticle/963104

Nov 17th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Patients on dialysis are known to be at notably higher risk of contracting SARS-CoV-2 and dying from COVID-19 than the general population, and now, for the first time, a large nationwide study pinpoints further specific risk factors for infection and mortality in this population, which in fact, ...

With COVID-19 Prevalent in Deer, Experts Urge Precautions
https://www.medscape.com/viewarticle/963114

Nov 17th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. With deer hunting season underway or starting in states across the U.S., people should wear a mask and gloves when handling deer to prevent coronavirus transmission, experts say. A recent study by researchers at Penn State University found that more than 80% of the deer sampled during last year'...

COVID Spread Among Deer Causes Concern Over New Variants
https://www.medscape.com/viewarticle/963175

Nov 17th, 2021 - Growing reports that white-tailed deer have been infected with SARS-CoV-2 and that some have become ill with COVID-19, along with continuing infections and illness in zoo animals and pets, is giving rise to concern among some experts that animals may become reservoirs for the development of new variants or even direct animal-to-human transmission. So far, it has mostly been humans who have infe...

Age, Geography Predict COVID-19 Vaccination of Vets With Cirrhosis
https://www.medscape.com/viewarticle/963021

Nov 16th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Vaccination against SARS-CoV-2 infection can protect patients with liver cirrhosis from decompensation, hospitalization, and death, but getting those patients to accept vaccination can be challenging. A retrospective study was conducted regarding the factors associated with failure of patients w...

Delta Dominates the World, but Scientists Watch for Worrisome Offspring
https://www.medscape.com/viewarticle/963030

Nov 16th, 2021 - CHICAGO (Reuters) - The Delta variant of the SARS-CoV-2 virus now accounts for nearly all of the coronavirus infections globally, fueled by unchecked spread of the novel coronavirus in many parts of the world. So far, vaccines are still able to defend against serious disease and death from Delta, but scientists remain on alert. Here is what we know: DELTA - STILL DOMINANT The Delta variant, fir...

COVID-19 Fatality Rate Among Children in England
https://www.medscape.com/viewarticle/963041

Nov 16th, 2021 - The fatality rate for COVID-19 in children and adolescents in England was five per 100,000 during the first year of the pandemic, however this increased to almost 90 per 100,000 among children with life-limiting neuro-disabilities. The figures were revealed through an in depth study published in Nature Medicine which used detailed clinical data in the National Child Mortality Database (NCMD) to...

Children With Cancer and COVID: Most Do Well, Which Ones Don't?
https://www.medscape.com/viewarticle/963049

Nov 16th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. A new study that followed 131 children with cancer who were infected with SARS-CoV-2 shows that most (79%) did well and had only asymptomatic or mild disease. However, others developed severe symptoms; 49 children (37%) were hospitalized, 15 (11%) required admission to the intensive care unit (I...

Anti-TNF Therapy Tied to Better Outcomes in IBD Patients With COVID-19
https://www.medscape.com/viewarticle/962869

Nov 15th, 2021 - NEW YORK (Reuters Health) - In patients with inflammatory bowel disease (IBD) who contracted COVID-19 infection, anti-tumor necrosis factor (anti-TNF) therapies were associated with more favorable outcomes than corticosteroids or mesalamine in a systematic review and analysis. "What was surprising was that patients with mild-to-moderate disease, who are typically treated with mesalamine compoun...

Confused About COVID-19 Boosters?
https://www.medscape.com/viewarticle/962969

Nov 15th, 2021 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. JOHN WHYTE: Are you confused about whether you should get a COVID vaccine booster shot? Let me help try to unpack it for you. Why do some people need boosters? Although COVID-19 vaccination remains effective in preventing severe disease, more and more data suggest vaccination is less effective at preventing in...

World at Risk of Measles Outbreaks as COVID-19 Disrupts Infant Shots, Report Says
https://www.medscape.com/viewarticle/962678

Nov 12th, 2021 - (Reuters) - The risk of measles outbreaks is high after more than 22 million infants missed their first vaccine doses during the COVID-19 pandemic in 2020, the World Health Organization (WHO) and the U.S. Centers for Disease Control and Prevention (CDC) warned. Reported measles cases fell by more than 80% last year compared with 2019, but a higher number of children missing their vaccine doses ...

EU Lists Rare Spinal Condition as Side Effect of J&J COVID-19 Shot
https://www.medscape.com/viewarticle/962776

Nov 12th, 2021 - (Reuters) - Europe's drug regulator has recommended adding a rare type of spinal inflammation called transverse myelitis as a side-effect of Johnson & Johnson's single-dose COVID-19 vaccine. Reports of this serious neurological illness were also at the heart of trial halts in the early stages of development for both AstraZeneca and J&J's shots, which are based on similar technology. On October ...

Miltefosine Granted Orphan Drug Approval for Invasive Candidiasis
https://www.medscape.com/viewarticle/962804

Nov 12th, 2021 - The US Food and Drug Administration (FDA) has granted orphan drug designation approval of miltefosine (Profounda, Inc) for the treatment of invasive candidiasis. This condition includes the potentially life-threatening candidemia, which is among the most common bloodstream infections in hospitalized patients in the United States. Miltefosine, a broad-spectrum antimicrobial phospholipid drug ori...

Big Bird Backlash: Vax Lands Even Muppet in Political Flap
https://www.medscape.com/viewarticle/962802

Nov 12th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. NASHVILLE, Tenn. (AP) — Smokey Bear taught kids the importance of preventing wildfires. McGruff the Crime Dog warned them not to talk to strangers. And in 1972, Big Bird lined up on "Sesame Street" to receive a measles vaccine as part of a campaign to get more youngsters inoculated against the d...

Johnson & Johnson to Split Into Two Companies
https://www.medscape.com/viewarticle/962807

Nov 12th, 2021 - Johnson & Johnson is splitting into two companies, peeling off the division selling Band-Aids and Listerine from its medical device and prescription drug business. The world's biggest maker of health care products, founded in 1886, said Friday the move will help improve the focus and speed of each company to address trends in their different industries. The company selling prescription drugs an...

From Cows to COVID: The Spooky Origins of Vaccines
https://www.medscape.com/viewarticle/962851

Nov 12th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Back in the 18th century, it was a wonder how anyone ever survived a trip to the doctor. Many didn't. England's drug stores were stocked with bulls' penises, frogs' lungs, and powdered Egyptian mummy, which was evidently used against tuberculosis. Syphilis, known as the "Great Pox," was treated ...

Increase in infections, Vaccine Mandatory for Children, and Restrictions for the Unvaccinated: COVID-19 Global Weekly Highlights
https://www.medscape.com/viewarticle/961934

Nov 12th, 2021 - These are the global coronavirus stories you need to know about this week. In the UK, despite criticism from the doctors' union the British Medical Association (BMA), the Government is making the COVID-19 jabs mandatory for NHS staff in England from April. The move follows compulsory vaccination in England’s care sector. This is coming at a time that a majority of health leaders are worried abo...