About 13,865 results

Overcrowding, Lack of Healthcare Access Help Increase COVID Mortality in Prisons

Nov 23rd, 2022 - Overcrowded conditions and lack of access to care help make COVID-19 more dangerous inside prisons, especially for minority populations, and these outbreaks are expected to continue, Neal Marquez, MPH, said at a webinar sponsored by Health Affairs. "Some people have said we're in the 'post-pandemic' era, but I do want to highlight that in our continued efforts to monitor COVID-19 in carceral se...

As He Steps Down, Fauci Urges Everyone to Get Flu, COVID Vaccines

Nov 22nd, 2022 - WASHINGTON -- Anthony Fauci, MD, used his last press conference at the White House on Tuesday to urge Americans to get their COVID-19 and flu vaccines. "Clinical efficacy data will be released [today] from CDC looking at the ability of the [COVID vaccine] to protect against the real-world BA.4/5 that's been circulating," said Fauci, who is the White House's chief medical advisor and the directo...

Anti-Vax Verified on Twitter; 'Laughing Gas' on the Rise; Medicare Advantage Errors

Nov 22nd, 2022 - Note that some links may require subscriptions. When it comes to vaccines, "verified" anti-vax accounts are proliferating on Twitter as the platform's content and curation controls shift in the wake of its recent ownership transition. (The Guardian) As this year's holiday (and respiratory virus) season heats up, this is how a bevy of infectious disease experts are currently responding to COVID,...

Monoclonal Antibodies May No Longer Be a Match for Emerging COVID Strains

Nov 18th, 2022 - Tixagevimab/cilgavimab (Evusheld) and bebtelovimab are likely ineffective against approximately 60% of currently circulating Omicron variants, creating a big gap in protection, particularly for immunocompromised individuals, researchers from a Harvard Medical School-led consortium said at a briefing on Thursday. This is a "big loss," said Jacob Lemieux, MD, PhD, of the Massachusetts Consortium ...

How the World Health Organization Might Fight Future Pandemics

Nov 18th, 2022 - GENEVA (Reuters) - Negotiations on new rules for dealing with pandemics are underway at the World Health Organization (WHO), with a target date of May 2024 for a legally binding agreement to be adopted by the U.N. health agency's 194 member countries. A new pact is a priority for WHO chief Tedros Adhanom Ghebreyesus as his second five-year term at the head of the global health agency gets under...

Fauci: 'I Have Nothing to Hide'; Title 42 Rule Blocked; Europe's Cancer 'Epidemic'

Nov 16th, 2022 - Note that some links may require subscriptions. "I have nothing to hide and I can defend everything we've done," said NIAID Director Anthony Fauci, MD, discussing the prospect of House investigations over the pandemic response under a Republican-led Congress. (STAT) Amazon is launching a virtual clinic to treat patients with allergies, hair loss, and acne. (CNBC) A federal judge has blocked the...

WHO Chief Scientist Departs Ahead of Broader Shake-Up

Nov 16th, 2022 - LONDON/GENEVA (Reuters) - The chief scientist of the World Health Organization said on Tuesday she was leaving the agency, the first of a series of high-profile departures expected at the global health body as it prepares for a post-pandemic future. The exit of Soumya Swaminathan, an Indian pediatrician, announced on Twitter, comes as Director-General Tedros Adhanom Ghebreyesus's second term as...

Haiti Cholera Outbreak Worsens, COVID-19 Cases Rise in Americas: PAHO

Nov 16th, 2022 - SAO PAULO (Reuters) - The cholera situation in Haiti continues to worsen while COVID-19 cases rose over the past week, the Pan American Health Organization (PAHO) said on Wednesday. Haitian health authorities have confirmed over 700 cases of cholera and 144 cholera-related deaths since early October, and are investigating more than 7,000 suspected cases, PAHO Director Dr. Carissa Etienne said. ...

Less and Late: UK Gives $1 Billion to Global Disease Fight

Nov 15th, 2022 - LONDON (Reuters) - The British government said on Monday it would contribute 1 billion pounds ($1.18 billion) to the Global Fund to fight AIDS, tuberculosis and malaria, more than six weeks after other countries made their commitments. The total, which covers 2023-25, is 30% less than Britain pledged during the previous funding round in 2019, and below the 1.8 billion pounds requested this time...

White House to Ask for $10 Billion in Public Health Funds by Year End: Report

Nov 15th, 2022 - (Reuters) - Officials from U.S. President Joe Biden's administration are finalizing a request this week for about $10 billion in public health funds by the end of the year, The Washington Post reported on Monday. This would be part of larger request in the lame-duck session of Congress that will include funding for Ukraine and disaster relief for hurricane damage in Florida, the article said. T...


COVID-19 is a respiratory disease caused by SARS-CoV-2. It spreads mainly from person to person.

Increasing Proportion of MDA-5 Associated Conditions in a Tertiary Myositis Centre Following Onset of the Covid-19 Pandemic
Jennifer Hannah, Saadia Sasha Ali, Sloni Arora et. al.

Nov 14th, 2022 - Background/Purpose: Anti-MDA5 dermatomyositis is a clinical subtype of DM that is strongly associated with a rapidly progressive phenotype of interstitial lung disease resulting in a high morbidity and mortality. MDA5 is an intracellular sensor of viral RNA that triggers an innate immune response in the healthy host important in upregulating a type1-IFN response. Viral infections have been cons...

Assessment of Antibody Levels to Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) in Patients with Idiopathic Inflammatory Myopathies Receiving Treatment with Intravenous Immunoglobulin
Sangmee Bae, emmanuelle Faure-Kumar, Jennifer Wang et. al.

Nov 14th, 2022 - Background/Purpose: Antibodies to Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) have been reported in pooled donor plasma and intravenous immunoglobulin products (IVIG) since May 2020 (C Romero 2021 PMID 33606999). It is not known whether regular administration of IVIG increases circulating anti-SARS-CoV-2 antibodies (COVID ab). The current work evaluates COVID ab titers in patie...

Clinical Outcomes Following Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Vaccination in Patients with Anti-Melanoma Differentiation Associated Gene 5 (MDA5) Antibody P...
Richard Seto, Sangmee Bae1 and Christina Charles-Schoeman, University of California Los Angeles et. al.

Nov 14th, 2022 - Background/Purpose: Patients with dermatomyositis (DM) and antibodies (ab) to melanoma differentiation associated gene 5 (MDA5) share similar clinical characteristics to patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) including high risk of fatal, rapidly progressive interstitial lung disease (RP-ILD). Nearly 50% of patients with COVID 19 have anti-MDA5 a...

Sociocultural and Moral Factors Influencing the Decision to Vaccinate Among Rheumatic Patients: A Qualitative Study
Tirsa Colmenares-Roa, Amaranta ManriquedeLara, Virginia Pascual Ramos et. al.

Nov 14th, 2022 - Background/Purpose: Vaccination is a process that involves individual, social and moral aspects, beyond public governance of vaccines or vaccination as a public health concern. The ways people incorporate their beliefs and concerns into vaccine decision-making affect the effectiveness of these interventions for individual and community health. The aim of this study is to describe the sociocultu...

Psychosocial and Health Measures in Systemic Lupus Erythematosus: COVID-19 Pandemic Trends in the Georgians Organized Against Lupus Cohort
Charmayne Dunlop-Thomas, Gaobin Bao, Jessica Williams et. al.

Nov 14th, 2022 - Background/Purpose: The COVID-19 pandemic may have a sustained impact on systemic lupus erythematosus (SLE) patients in multiple ways. In a large predominantly Black SLE cohort, we explored trends in lupus disease activity, general health, and psychosocial factors at 3-time points: pre-pandemic, early pandemic, and later pandemic. Methods: We examined longitudinal data from people with SLE enro...

COVID-19 Cases in Patients Treated with Secukinumab: Analysis from the Global Safety Database
Atul Deodhar, Andrew Blauvelt, Philip J Mease et. al.

Nov 14th, 2022 - Background/Purpose: Although patients (pts) with immune-mediated inflammatory diseases who are taking immunosuppressive therapies are not at a significantly greater risk of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection, the reported risk of severe unfavorable outcome or sequalae varies among studies1,2. As specific data in pts treated with secukinumab are lacking, we an...

Immune Responses to mRNA Vaccines Against SARS-CoV-2 in Patients with Immune-mediated Inflammatory Rheumatic Diseases
Cristiana Sieiro Santos, Sara Calleja Antolín, Clara Moriano Morales et. al.

Nov 14th, 2022 - Background/Purpose: Patients with immune-mediated rheumatic diseases (IMRDs) are commonly treated with immunosuppressors and prone to infections. Recently introduced mRNA SARS-CoV-2 vaccines have demonstrated extraordinary efficacy across all ages. Immunosuppressed patients were excluded from phase III trials with SARS-CoV-2 mRNA vaccines. We aim to fully characterise B-cell and T-cell immune r...

Clinical and Immunological Factors Associated with Chronic Post-COVID19 Syndrome 12 Months After Acute Infection
Emmanuel Abimelec Camacho-Morán, jiram torres-Ruiz, Jaquelin Lira-Luna et. al.

Nov 14th, 2022 - Background/Purpose: Post-COVID19 syndrome has been defined as the persistence of symptoms and/or organic damage for more than three weeks after the presence of clinical infection caused by SARS-CoV-2. It is further divided into two categories: subacute and chronic post-COVID19 syndrome. A model that includes clinical, immunological, and metabolic factors regarding this phenomenon have not been ...

Adverse Events in Patients with Inflammatory Joint Diseases: Results from the EULAR Coronavirus Vaccine (COVAX) Physician-reported Registry
Ana Lúcia Martins Fernandes, Jose A Gomez-Puerta, Juan Camilo Sarmiento-Monroy et. al.

Nov 14th, 2022 - Background/Purpose: Patients with inflammatory/autoimmune rheumatic and musculoskeletal diseases (I-RMDs) were excluded from SARS-CoV-2 vaccination development programs. Therefore, concerns regarding the safety and effectiveness of SARS-CoV-2 vaccines in this population arose. Previous reports capturing a wide range of I-RMDs have been reassuring [1], but more granular data on specific conditio...