About 1,648 results

To Study Zika, They Offered Their Kids. Then They Were Forgotten.

Oct 6th, 2021 - Rochelle dos Santos embraces her daughter, who was born with microcephaly in 2016 after dos Santos contracted Zika during her pregnancy in midwest Brazil. Rochelle Dos Santos learned that her daughter would probably be born with microcephaly — a condition where a baby's head is much smaller than expected — when she was seven months pregnant. It was 2016 and Brazil was going through an unprecede...

The Case of Billy Best: 25 Years Later.
Pediatrics Marron JM, Mithani Z et. al.

Aug 21st, 2021 - Billy Best was diagnosed with Hodgkin lymphoma in 1994 at age 16 and became well-known when he ran away from home to avoid receiving further chemotherapy. His story became national news when, with the support of his adopted parents, he returned home and opted to use complementary and alternative medicine (CAM) instead of standard chemotherapy and radiation for his cancer treatment. Now 25 years...

SARS-CoV-2 Human Challenge Studies - Establishing the Model during an Evolving Pandemic.
The New England Journal of Medicine; Rapeport G, Smith E et. al.

Jul 22nd, 2021 - SARS-CoV-2 Human Challenge Studies - Establishing the Model during an Evolving Pandemic.|2021|Rapeport G,Smith E,Gilbert A,Catchpole A,McShane H,|therapeutic use,immunology,prevention & control,therapy,ethics,organization & administration,standards,

Designer Babies Are No Longer Theoretical. What Could Go Wrong?

Jul 8th, 2021 - This transcript has been edited for clarity. Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I'm Dr F. Perry Wilson of the Yale School of Medicine. Imagine that you are about to start a family. Would you want the ability to choose whether your child would have cystic fibrosis or not? Would you want to be able to choose if that first child would be a boy or a gir...

Pharmacy Exec in Deadly US Meningitis Outbreak Gets Stiffer, 14-1/2 Year Prison Term

Jul 8th, 2021 - BOSTON (Reuters) - A founder of a Massachusetts compounding pharmacy whose mold-tainted drugs sparked a deadly U.S. fungal meningitis outbreak in 2012 was resentenced on Wednesday to 14-1/2 years in prison after a federal appeals court overturned his earlier 9-year term. U.S. District Judge Richard Stearns in Boston said the appellate court at least implicitly deemed as too light the original s...

Should a Clinician Be Punished for Exposing Others to COVID-19?

Jul 7th, 2021 - A physician in Providence, Rhode Island faces thousands of dollars in fines from the US Department of Labor's Occupational Safety and Health Administration for exposing patients and staff to COVID-19 while he was ill and failing to take necessary pandemic precautions in his offices. His license to practice medicine was also temporarily suspended earlier this year. Staff reported that the physic...

A reasoned approach towards administering COVID-19 vaccines to pregnant women.
Prenatal Diagnosis; Pramanick A, Kanneganti A et. al.

Jul 1st, 2021 - There are over 50 SARS-CoV-2 candidate vaccines undergoing Phase II and III clinical trials. Several vaccines have been approved by regulatory authorities and rolled out for use in different countries. Due to concerns of potential teratogenicity or adverse effect on maternal physiology, pregnancy has been a specific exclusion criterion for most vaccine trials with only two trials not excluding ...

Serotonin/HTR1E signaling blocks chronic stress-promoted progression of ovarian cancer.
Theranostics Qin X, Li J et. al.

Jun 8th, 2021 - Rationale: Psychological stress has been linked to cancer development and resistance to therapy by many epidemiological and clinical studies. Stress-induced immunosuppressive microenvironment by stress hormones, in particular glucocorticoids, has been extensively studied. However, the impacts of other stress-related neurotransmitters, such as serotonin (5-hydroxytryptamine, 5-HT), on cancer dev...

Are SARS-CoV-2 Human Challenge Trials Ethical?
JAMA Internal Medicine; Sulmasy DP

Jun 8th, 2021 - Are SARS-CoV-2 Human Challenge Trials Ethical?|2021|Sulmasy DP,|epidemiology,ethics,

Are These Docs Paid to Change Their Medical Opinion? Black Lungs, Big Coal, and Bias

Jun 3rd, 2021 - In 2008, the Department of Labor (DOL) paid for Tony Adams, a 48-year-old coal miner, to have a chest x-ray. His doctor found stage I black lung disease. Yet Adams' claim for medical benefits was denied. This was because the insurance group that represented his employer hired a different ― more credentialed ― doctor as their medical expert. That doctor said he saw no such evidence. The judge ru...

You Want To Do What? Paper on Anal Swabs for COVID-19 Retracted for Ethical Issues

Apr 16th, 2021 - An article claiming that anal swabs can be used to detect SARS-CoV-2 in patients cured of Covid-19 has been retracted after the journal found that the authors failed to get permission from the patients to conduct the study.  To be clear: We're not sure if the researchers — from Weihai Municipal Hospital, in Shandong, China — didn't tell the patients they were taking anal swabs (which seems, wel...

Kick U.S. Kids to the Back of the Global Vax Line

Apr 7th, 2021 - Having multiple highly effective vaccines for SARS-CoV-2 is terrific, but it is not the end of the story. Who should get vaccinated first, second, and third remains a vital question. When vaccines first reached medical centers, some were angry with hospitals' prioritization decisions. At some centers, older faculty, who may not have had much patient contact, were vaccinated ahead of residents, ...

Step Therapy: Inside the Fight Against Insurance Companies and 'Fail First' Medicine

Mar 26th, 2021 - Every day Melissa Fulton, RN, MSN, FNP, APRN-C, shows up to work, she's ready for another fight. An advanced practice nurse who specializes in multiple sclerosis care, Fulton says she typically spends more than a third of her time battling it out with insurance companies over drugs she knows her patients need but that insurers don't want to cover. Instead, they want the patient to first receive...

Pseudoscience Royal Rumble: Doc vs The Rock

Mar 24th, 2021 - Following is a transcript of this video; note that errors are possible: Rohin Francis, MBBS: This isn't a video... [BEEPING] Many hours later, well, let's try this again. It's now the night and for some reason my right ear is exceedingly hot. Now, this is a totally unplanned video. It's not the one I intended to be working on at the moment, but I couldn't miss the opportunity to tell you about ...

Smallpox vaccination in the 19th century.
Journal of the American Geriatrics Society; Levine JM

Mar 23rd, 2021 - Smallpox vaccination in the 19th century.|2021|Levine JM,|ethics,prevention & control,prevention & control,psychology,

Neuroscience Letters: Third Journal Scammed by Rogue Editors

Mar 19th, 2021 - Burned by the offer of a special issue, a journal has retracted four papers after determining that the guest editors of the supplement were not legit.  Neuroscience Letters, an Elsevier title, published the special issue — "Special Issue on Clinical and Imaging Assessment of Cognitive Dysfunction in Neurological and Psychiatric Disorders" — last summer, but it's no longer on the journal's websi...

Are COVID-19 Human Infection Trials Ethical?

Mar 15th, 2021 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The United Kingdom has a long history of conducting experimental human infection trials. People in the UK vacationed at "flu camps" where they were paid to be infected with flu viruses. The camps closed in the 1980s, but some universities replicated the concept, and it's now being done for COVID-19. These chal...

EU Investigating Teva for Blocking Rivals to Multiple Sclerosis Drug

Mar 5th, 2021 - BRUSSELS (Reuters) - Israeli drugmaker Teva is being investigated by EU antitrust regulators who are looking into whether it illegally hindered rivals' access to its multiple sclerosis medicine Copaxone. The European Commission, which carried out unannounced inspections of Teva in 2019 and 2020, said the probe will look into whether Teva has abused its dominant market position in breach of EU a...

Implementing digital passports for SARS-CoV-2 immunization in Canada.
CMAJ : Canadian Medical Association Journal = Journal De ... Wilson K, Flood CM

Mar 5th, 2021 - Implementing digital passports for SARS-CoV-2 immunization in Canada.|2021|Wilson K,Flood CM,|prevention & control,supply & distribution,ethics,ethics,legislation & jurisprudence,prevention & control,ethics,legislation & jurisprudence,

Rabies Is Terrifying but Rare. Are We Overtreating It?

Feb 18th, 2021 - Rabies is a terrifying disease. Once the virus enters a human host — typically by way of a bite from an infected animal — it creeps along from nerve cell to nerve cell until it reaches the brain. It usually takes a month or more for symptoms to show. But when they do, the ensuing illness is usually marked by chilling neurological signs: delirium, hallucinations, aggressiveness, and a combinatio...