About 1,910 results

Run Into a Rabid Animal? What to Know

Apr 11th, 2022 - News of rabid foxes or other animals doesn't make quite as much of a stir here in Western Maryland as it did on Capitol Hill. Here, it seems to be more regarded as a hazard of country living. https://twitter.com/thecapitolfox/status/1511407331661262861?s=20&t=PgQSZc3O9K1HF8Ez1hDXHA Admittedly, my enthusiasm for seeing the beautiful creatures has waned over the years. And I don't dissect dead an...

Brain Implant Allows Totally Paralyzed Patient to Communicate

Mar 24th, 2022 - An experimental brain-computer interface has allowed a man with amyotrophic lateral sclerosis (ALS) who was unable to speak or move to communicate. Using a commercially available implant and newly designed software, the patient, who spoke German and was in the advanced stages of ALS and couldn't move his eyes, was able to interact with researchers and caregivers. Initially he was able to correc...

Experts Question Whether It's Okay to Test Embryos for Common Diseases

Mar 21st, 2022 - Scientists said they can predict the risk of common diseases, such as breast cancer and diabetes, in in vitro-fertilized embryos by combining "molecular and statistical techniques," but ethicists and other experts are sounding the alarm over the clinical use of such technologies. Among 10 couples who underwent in vitro fertilization (IVF), results from whole-genome reconstruction using the pare...

Injecting Asbestos: Prison Studies Revealed in J&J Talc Lawsuits

Mar 15th, 2022 - For the past eight years, Johnson & Johnson (J&J) has been dealing with lawsuits from women claiming that they developed ovarian cancer after using the company's talc products. Documents unsealed during these proceedings show that the company was involved in a study in which incarcerated men were paid to be injected with asbestos in order that the company could compare its effect on their skin ...

Outlook on Chronic Lymphocytic Leukemia: From Theory to Practice

Feb 10th, 2022 - Deborah M. Stephens, DO, reflects on how early research training with a mentor resulted in a determination to subspecialize in chronic lymphocytic leukemia, and how this formative experience fostered a patient-centered ethic which she later carried into her own practice.

How informative were early SARS-CoV-2 treatment and prevention trials? a longitudinal c...
PloS One; Hutchinson N, Klas K et. al.

Jan 22nd, 2022 - Early in the SARS-CoV-2 pandemic, commentators warned that some COVID trials were inadequately conceived, designed and reported. Here, we retrospectively assess the prevalence of informative COVID trials launched in the first 6 months of the pandemic. Based on prespecified eligibility criteria, we created a cohort of Phase 1/2, Phase 2, Phase 2/3 and Phase 3 SARS-CoV-2 treatment and prevention ...

Ethical considerations for introducing RTS,S/AS01 in countries with moderate to high Pl...
The Lancet. Global Health; D'Souza J, Nderitu D

Nov 20th, 2021 - Ethical considerations for introducing RTS,S/AS01 in countries with moderate to high Plasmodium falciparum malaria transmission.|2021|D'Souza J,Nderitu D,|therapeutic use,prevention & control,ethics,

Many trials of hydroxychloroquine for SARS-CoV-2 were redundant and potentially unethic...
Journal of Clinical Epidemiology; Yogendrakumar V, Dewar B et. al.

Nov 16th, 2021 - We sought to map the landscape of trials investigating hydroxychloroquine (HCQ) for SARS-CoV-2 in order to draw conclusions about how clinical trials have been conducted in the pandemic environment and offer potential regulatory recommendations. We identified and captured data related to registered studies using HCQ to treat SARS-CoV-2 registered with the publicly available National Institutes ...

Beloved Psychiatrist Dies at 102

Oct 22nd, 2021 - Respected psychiatrist and psychoanalyst Irwin Marcus, MD, died on October 3. He was 102. Dedicated to his profession, Marcus was seeing patients until earlier this year. His long and illustrious career included creating and founding programs and organizations wherever he saw a need. Among his many professional accomplishments, Marcus helped found the child and adolescent psychiatry program at ...

AAN Blasts 'Runaway' Neurology, Other Prescription Drug Costs

Oct 12th, 2021 - A new position statement from the American Academy of Neurology (AAN) and other organizations warns soaring prices for neurologic and other prescription medications is leading to rationing of care and diverting clinicians' time from the clinic to insurance bureaucracy. This situation is also taking a toll on neurologists' mental health, who already have the second-highest burnout rate across me...

Why Vaccine and Mask Mandates Hold Up in Court

Oct 12th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. President Joe Biden's announcement in September that large companies will soon be required to mandate COVID-19 vaccines or weekly testing for employees set off a domino effect of legal challenges in various states. Court cases began to crop up even before that when mask mandates came into play. ...

To Study Zika, They Offered Their Kids. Then They Were Forgotten.

Oct 6th, 2021 - Rochelle dos Santos embraces her daughter, who was born with microcephaly in 2016 after dos Santos contracted Zika during her pregnancy in midwest Brazil. Rochelle Dos Santos learned that her daughter would probably be born with microcephaly — a condition where a baby's head is much smaller than expected — when she was seven months pregnant. It was 2016 and Brazil was going through an unprecede...

Trust and shared decision-making among individuals with multiple myeloma: A qualitative...
Cancer Medicine; Whitney RL, White AEC et. al.

Oct 6th, 2021 - Multiple myeloma (MM) is an incurable cancer with complex treatment options. Trusting patient-clinician relationships are essential to promote effective shared decision-making that aligns best clinical practices with patient values and preferences. This study sought to shed light on the development of trust between MM patients and clinicians. Nineteen individual semi-structured interviews were ...

Forget Privacy; Vaccine Passports Are Sorely Needed

Oct 4th, 2021 - This transcript has been edited for clarity. Hi. I'm Art Caplan. I'm at the New York University Grossman School of Medicine, where I run the Division of Medical Ethics. There has been much discussion lately about vaccine mandates. I support vaccine mandates. I think there are too many unvaccinated people in the United States, and I think governments and private employers should be pushing harde...

Research with variola virus after smallpox eradication: Development of a mouse model fo...
PLoS Pathogens; Moss B, Smith GL

Sep 22nd, 2021 - Research with variola virus after smallpox eradication: Development of a mouse model for variola virus infection.|2021|Moss B,Smith GL,|ethics,

Lack of equipoise in the LIGHTHOUSE trial for patients with relapsed multiple myeloma: ...
European Journal of Cancer (Oxford, England : 1990); Mohyuddin GR, Banerjee R et. al.

Sep 22nd, 2021 - Lack of equipoise in the LIGHTHOUSE trial for patients with relapsed multiple myeloma: An ethical concern.|2021|Mohyuddin GR,Banerjee R,Goodman AM,|ethics,ethics,drug therapy,drug therapy,ethics,

The Case of Billy Best: 25 Years Later.
Pediatrics Marron JM, Mithani Z et. al.

Aug 21st, 2021 - Billy Best was diagnosed with Hodgkin lymphoma in 1994 at age 16 and became well-known when he ran away from home to avoid receiving further chemotherapy. His story became national news when, with the support of his adopted parents, he returned home and opted to use complementary and alternative medicine (CAM) instead of standard chemotherapy and radiation for his cancer treatment. Now 25 years...

Neuroscientist's Work Earns Three Expressions of Concern

Aug 6th, 2021 - A journal has issued expressions of concern for three papers from 2014 and 2015 by a group at Stony Brook University in New York whose work has come under scrutiny on PubPeer for suspect images. The articles, which appeared in the Journal of Neuroscience, were written by Adan Aguirre, a pharmacological scientist at Stony Brook, and his colleagues. Several other papers by Aguirre's group — in va...

Despite Retraction, Study Using Fraudulent Surgisphere Data Still Cited

Aug 5th, 2021 - A retracted study on the safety of blood pressure medications in patients with COVID-19 continues to be cited nearly a year later, new research shows. The study in question, published on May 1, 2020 in the New England Journal of Medicine (NEJM), showed no increased risk for in-hospital death with the use of angiotensin-converting-enzyme (ACE) inhibitors or angiotensin-receptor blockers (ARBs) i...

SARS-CoV-2 Human Challenge Studies - Establishing the Model during an Evolving Pandemic.
The New England Journal of Medicine; Rapeport G, Smith E et. al.

Jul 22nd, 2021 - SARS-CoV-2 Human Challenge Studies - Establishing the Model during an Evolving Pandemic.|2021|Rapeport G,Smith E,Gilbert A,Catchpole A,McShane H,|therapeutic use,immunology,prevention & control,therapy,ethics,organization & administration,standards,