About 3,795 results

Public investments in the development of GeneXpert molecular diagnostic technology.
PloS One; Gotham D, McKenna L et. al.

Sep 1st, 2021 - The GeneXpert diagnostic platform from the US based company Cepheid is an automated molecular diagnostic device that performs sample preparation and pathogen detection within a single cartridge-based assay. GeneXpert devices can enable diagnosis at the district level without the need for fully equipped clinical laboratories, are simple to use, and offer rapid results. Due to these characteristi...

The 1942 Massive Contamination of Yellow Fever Vaccine: A Public Health Consequence of ...
American Journal of Public Health; Löwy I

Aug 20th, 2021 - In the late 1930s, the 17D vaccine against yellow fever was produced in record time. 17D was and is an excellent vaccine. Its rapid diffusion led, however, to several problems, the most important among them being the 1942 massive contamination of the vaccine distributed to the US Army by the hepatitis B virus. The US part of this story is relatively well-known, but its Brazilian part much less ...

Elizabeth Ashley-leading research at malaria's frontline.
The Lancet. Infectious Diseases; Kenyon G

Aug 1st, 2021 - Elizabeth Ashley-leading research at malaria's frontline.|2021|Kenyon G,|history,

ENDOCRINOLOGY IN THE TIME OF COVID-19-2021 UPDATES: The management of diabetes insipidu...
European Journal of Endocrinology; Christ-Crain M, Hoorn EJ et. al.

Jul 23rd, 2021 - COVID-19 has changed the nature of medical consultations, emphasizing virtual patient counselling, with relevance for patients with diabetes insipidus (DI) or hyponatraemia. The main complication of desmopressin treatment in DI is dilutional hyponatraemia. Since plasma sodium monitoring is not always possible in times of COVID-19, we recommend to delay the desmopressin dose once a week until aq...

One hundred years of zoonoses research in the Horn of Africa: A scoping review.
PLoS Neglected Tropical Diseases; Cavalerie L, Wardeh M et. al.

Jul 17th, 2021 - One Health is particularly relevant to the Horn of Africa where many people's livelihoods are highly dependent on livestock and their shared environment. In this context, zoonoses may have a dramatic impact on both human and animal health, but also on country economies. This scoping review aimed to characterise and evaluate the nature of zoonotic disease research in the Horn region. Specificall...

Art in support of life: Caravaggio and the plague.
The Journal of Analytical Psychology; Vezzoli C

Jul 8th, 2021 - In the struggle with COVID-19, art offered a way to face the solitude of the lockdown. The focus of this paper is primarily on Caravaggio's painting The Seven Works of Mercy, with references to other paintings to amplify some aspects of the artist's approach to life and his uniqueness in the artistic landscape of his time. Darkness was part of Caravaggio's research for spiritual truth and by en...

The Cost of Tuberculosis.

Jul 7th, 2021 - The Cost of Tuberculosis.|2021||history,economics,history,mortality,epidemiology,

Against settler colonial iatrogenesis: Inuit resistance to treatment in Indian Hospital...
Anthropology & Medicine; Granzow K

Jun 26th, 2021 - Canada's program to examine, transfer and treat Indigenous and Inuit peoples with tuberculosis in Indian Hospitals (ca. 1936 and 1969) has generally been framed by official narratives of population health, benevolence, and care. However, letters written by Inuit patients in Indian hospitals and their kin, and which were addressed to government officials and translated by government employees, c...

Dating first cases of COVID-19.
PLoS Pathogens; Roberts DL, Rossman JS et. al.

Jun 25th, 2021 - Questions persist as to the origin of the COVID-19 pandemic. Evidence is building that its origin as a zoonotic spillover occurred prior to the officially accepted timing of early December, 2019. Here we provide novel methods to date the origin of COVID-19 cases. We show that six countries had exceptionally early cases, unlikely to represent part of their main case series. The model suggests a ...

BCG turns 100: its nontraditional uses against viruses, cancer, and immunologic diseases.
The Journal of Clinical Investigation; Singh AK, Netea MG et. al.

Jun 2nd, 2021 - First administered to a human subject as a tuberculosis (TB) vaccine on July 18, 1921, Bacillus Calmette-Guérin (BCG) has a long history of use for the prevention of TB and later the immunotherapy of bladder cancer. For TB prevention, BCG is given to infants born globally across over 180 countries and has been in use since the late 1920s. With about 352 million BCG doses procured annually and t...

Precedent for the Present: Neurosurgery During the 1918 Wartime Influenza Pandemic.
World Neurosurgery; Stone LE

May 31st, 2021 - In the early twentieth century, early neurosurgical pioneers marked their claims in the specialty during the combined threats of the Spanish influenza and World War I. Their stories, intimately connected, demonstrate personal and professional losses in the backdrop of overarching perseverance to achieve that which allowed neurosurgery to evolve into modernity. Today, as global order adapts to t...

Research trends for papillary thyroid carcinoma from 2010 to 2019: A systematic review ...
Medicine Huang F, Wang L et. al.

May 26th, 2021 - Thyroid carcinoma comprises the fastest rising incidence of carcinomas over the past decade. Papillary thyroid carcinoma (PTC) is the most predominant type of thyroid carcinoma. This study aimed to assess the research trends in the field of PTC. Publications from January 2010 to December 2019 were retrieved from the Web of Science Core Collection database using Thompson Reuters. Searching strat...

50 Years Ago in TheJournalofPediatrics: DNA Antibody Testing for Childhood Systemic Lup...
The Journal of Pediatrics; Ashkenazi L, Hashkes PJ

May 26th, 2021 - 50 Years Ago in TheJournalofPediatrics: DNA Antibody Testing for Childhood Systemic Lupus Erythematosus (cSLE): Going Far(r).|2021|Ashkenazi L,Hashkes PJ,|blood,immunology,diagnosis,history,history,

50 Years Ago in TheJournalofPediatrics: Inflammation and Vasculitis: Changing Paradigms.
The Journal of Pediatrics; Gidding SS

May 26th, 2021 - 50 Years Ago in TheJournalofPediatrics: Inflammation and Vasculitis: Changing Paradigms.|2021|Gidding SS,|history,history,history,history,

50 Years Ago in TheJournalofPediatrics: Pregnancy in Women with Galactosemia.
The Journal of Pediatrics; Almaas R, Saugstad OD

May 26th, 2021 - 50 Years Ago in TheJournalofPediatrics: Pregnancy in Women with Galactosemia.|2021|Almaas R,Saugstad OD,|complications,history,history,etiology,

50 Years Ago in TheJournalofPediatrics: The Baptism of Staphylococcal Scalded Skin Synd...
The Journal of Pediatrics; Dhir SK, Gupta P

May 26th, 2021 - 50 Years Ago in TheJournalofPediatrics: The Baptism of Staphylococcal Scalded Skin Syndrome: Old is Gold.|2021|Dhir SK,Gupta P,|therapeutic use,therapeutic use,history,history,drug therapy,history,

The Reign of the Ventilator: Acute Respiratory Distress Syndrome, COVID-19, and Technol...
Annals of Internal Medicine; Prkachin Y

May 4th, 2021 - In the early phase of the COVID-19 pandemic, a dispute arose as to whether the disease caused a typical or atypical version of acute respiratory distress syndrome (ARDS). This essay recounts the emergence of ARDS and places it in the context of the technological transformation of modern hospital care-particularly the emergence of intensive care after the 1952 Copenhagen polio epidemic. The poli...

The spatiotemporal distribution of historical malaria cases in Sweden: a climatic persp...
Malaria Journal; Chen TT, Ljungqvist FC et. al.

May 3rd, 2021 - Understanding of the impacts of climatic variability on human health remains poor despite a possibly increasing burden of vector-borne diseases under global warming. Numerous socioeconomic variables make such studies challenging during the modern period while studies of climate-disease relationships in historical times are constrained by a lack of long datasets. Previous studies have identified...

The Face Mask at the Intersection of Preventive Science, Domestic Politics, and Interna...
Journal of Laparoendoscopic & Advanced Surgical Technique... Kristo G, He K et. al.

Apr 24th, 2021 - Background: The face mask has been used to protect against airborne diseases throughout history. We conducted a historical review of the literature on the origin of the face mask, the scientific evidence of its benefits, and its implications for domestic and international politics. Material and Methods: We performed a comprehensive search for peer- and nonpeer- reviewed literature published bet...

Testicular cancer follow-up costs in Germany from 2000 to 2015.
Journal of Cancer Research and Clinical Oncology; Michaeli T, Michaeli J et. al.

Apr 23rd, 2021 - Advances in testicular cancer screening and therapy increased 10-year survival to 97% despite a rising incidence; eventually expanding the population of survivors requiring follow-up. We analyzed 10-year follow-up costs after testicular cancer treatment in Germany during 2000, 2008, and 2015. Testicular cancer follow-up guidelines were extracted from the European Association of Urology. Per pat...