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About 3,413 results

Resuscitative endovascular balloon occlusion of the aorta in Canada: a context-specific...
https://doi.org/10.1503/cjs.015319
Canadian Journal of Surgery. Journal Canadien De Chirurgie; Bradley NL, Leeper WR et. al.

May 12th, 2022 - SummaryResuscitative endovascular balloon occlusion of the aorta (REBOA) is a well-described intervention for noncompressible torso hemorrhage. Several Canadian centres have included REBOA in their hemorrhagic shock protocols. However, REBOA has known complications and equipoise regarding its use persists. The Canadian Collaborative on Urgent Care Surgery (CANUCS) comprises surgeons who provide...

Management of femoral head fracture by Ganz surgical dislocation of the hip.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9091069
Journal of Orthopaedics and Traumatology : Official Journ... Hosny H, Mousa S et. al.

May 11th, 2022 - Posterior hip dislocation is the commonest type of hip dislocation. It is associated with femoral head fracture in 7% of cases. Urgent and congruent hip reduction is mandatory to improve clinical outcomes and avoid irreversible complications. The purpose of this study is to assess the safety and functional and radiological outcomes of surgical hip dislocation by Ganz technique for treatment of ...

Prophylactic Ureteral Catheter Placement Appears to Reduce Intraoperative Ureteric Inju...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047802
Technology in Cancer Research & Treatment; Chen X, Chen J et. al.

Apr 21st, 2022 - Background: Prophylactic ureteral catheters placement (PUCP) was advocated as an effective strategy for decreasing ureteral morbidities in colorectal surgeries. However, whether it should be routinely used prior to primary retroperitoneal liposarcoma (PRLS) surgeries remains unknown. Methods: It was a retrospective study, conducted at a tertiary sarcoma center. Medical records of patients with ...

Association of Playing College American Football With Long-term Health Outcomes and Mor...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021915
JAMA Network Open; Phelps A, Alosco ML et. al.

Apr 21st, 2022 - Exposure to repetitive head impacts from playing American football (including impacts resulting in symptomatic concussions and subconcussive trauma) is associated with increased risk for later-life health problems, including cognitive and neuropsychiatric decline and neurodegenerative disease. Most research on long-term health consequences of playing football has focused on former professional ...

Interface astrogliosis in contact sport head impacts and military blast exposure.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009003
Acta Neuropathologica Communications; Babcock KJ, Abdolmohammadi B et. al.

Apr 15th, 2022 - Exposure to military blast and repetitive head impacts (RHI) in contact sports is associated with increased risk of long-term neurobehavioral sequelae and cognitive deficits, and the neurodegenerative disease chronic traumatic encephalopathy (CTE). At present, the exact pathogenic mechanisms of RHI and CTE are unknown, and no targeted therapies are available. Astrocytes have recently emerged as...

Re-thinking lactation-related nipple pain and damage.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966064
Women's Health (London, England); Douglas P

Mar 29th, 2022 - Nipple pain is a common reason for premature cessation of breastfeeding. Despite the benefits of breastfeeding for both infant and mother, clinical support for problems such as maternal nipple pain remains a research frontier. Maternal pharmaceutical treatments, and infant surgery and bodywork interventions are commonly recommended for lactation-related nipple pain without evidence of benefit. ...

Promethazine Downregulates Wnt/β-Catenin Signaling and Increases the Biomechanical Forc...
https://doi.org/10.1177/03635465221077116
The American Journal of Sports Medicine; Sakaguchi T, Ohkawara B et. al.

Mar 3rd, 2022 - Wnt/β-catenin signaling suppresses the differentiation of cultured tenocytes, but its roles in tendon repair remain mostly elusive. No chemical compounds are currently available to treat tendon injury. We hypothesized that the inhibition of Wnt/β-catenin signaling would accelerate tendon healing. Controlled laboratory study. Tendon-derived cells (TDCs) were isolated from rat Achilles tendons. T...

Survivor of Right Atrial Appendage Rupture Following Blunt Chest Trauma.
https://doi.org/10.1177/00031348211054068
The American Surgeon; Read MD, Sunderland MS et. al.

Mar 1st, 2022 - A 20-year-old woman presented to our trauma center with cardiac rupture after a motor vehicle collision. Our patient was the restrained driver in a high-speed collision. She arrived without external evidence of trauma but in obvious distress with tachycardia, tachypnea, and hypotension. Initial FAST was negative and chest x-ray; however, second FAST was equivocal for pericardial fluid. Computed...

When Is an Isolated Olecranon Fracture Pathognomonic for Osteogenesis Imperfecta?
https://doi.org/10.1097/BPO.0000000000002100
Journal of Pediatric Orthopedics; VanEenenaam DP, Houlihan N et. al.

Feb 25th, 2022 - Isolated fractures of the olecranon process of the ulna in pediatric patients with open physes are classically considered pathognomonic for osteogenesis imperfecta (OI). The purpose of this study was to distinguish the clinical manifestations of isolated olecranon fractures in patients with and without OI to help practitioners assess when further evaluation for OI may be necessary. All patients...

SARS-CoV-2 infection causes intestinal cell damage: Role of interferon's imbalance.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828414
Cytokine Guimarães Sousa S, Kleiton de Sousa A et. al.

Feb 15th, 2022 - Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative agent of the newly emerging lung disease pandemic COVID-19. This viral infection causes a series of respiratory disorders, and although this virus mainly infects respiratory cells, the small intestine can also be an important site of entry or interaction, as enterocytes highly express in angiotensin-2 converting enzym...

Increased risk of hepatocellular carcinoma in patients with traumatic liver injury: Rea...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830875
Medicine Chen YJ, Shen CJ et. al.

Feb 12th, 2022 - Hepatocellular carcinoma (HCC) is the sixth most common cancer globally, and liver is one of the most commonly injured organs after blunt abdominal trauma. The traumatic liver injury-HCC risk relationship remains unclear.We extracted data of patients with traumatic liver injury between 2000 and 2013 from Taiwan National Health Insurance Research Database (n = 15,966) and those of age-, gender-,...

Maternal regulation of biliary disease in neonates via gut microbial metabolites.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748778
Nature Communications; Jee JJ, Yang L et. al.

Jan 12th, 2022 - Maternal seeding of the microbiome in neonates promotes a long-lasting biological footprint, but how it impacts disease susceptibility in early life remains unknown. We hypothesized that feeding butyrate to pregnant mice influences the newborn's susceptibility to biliary atresia, a severe cholangiopathy of neonates. Here, we show that butyrate administration to mothers renders newborn mice resi...

Round window membrane rupture following blunt force trauma.
https://doi.org/10.1308/rcsann.2021.0056
Annals of the Royal College of Surgeons of England; Cho WS, Koju G et. al.

Jan 2nd, 2022 - Round window rupture following barotrauma such as diving and air travel is well documented. However, we describe a case of round window rupture following a slap to the ear, which has not been described previously. A 12-year-old boy was slapped by his teacher in rural Nepal over his left ear and immediately noted hearing loss. There was no dizziness or tinnitus. He presented to our unit 21 days ...

Impact of age on mortality and complications in patients with Ankylosing Spondylitis sp...
https://doi.org/10.1016/j.jocn.2021.11.035
Journal of Clinical Neuroscience : Official Journal of Th... Sharma M, Jain N et. al.

Dec 21st, 2021 - The aim of this retrospective cohort study was to study the impact of age on in-hospital complications and mortality following surgery for Ankylosing Spondylitis (AS) associated spine fractures. We extracted data from the Nationwide Inpatient Sample (NIS) database (1998-2018) using ICD-9/10 codes. Patients with a primary diagnosis of AS associated spine fractures who underwent fusion surgery we...

Association of SARS-COV2 and Lumbar Spine Fractures: Causal or Coincidental?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616711
Journal of Clinical Densitometry : the Official Journal O... Boussaid S, Makhlouf Y et. al.

Dec 19th, 2021 - Association of SARS-COV2 and Lumbar Spine Fractures: Causal or Coincidental?|2021|Boussaid S,Makhlouf Y,Jammali S,Sahli H,Elleuch M,|complications,virology,injuries,complications,etiology,

Incidence of and Mortality From Amyotrophic Lateral Sclerosis in National Football Leag...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674746
JAMA Network Open; Daneshvar DH, Mez J et. al.

Dec 16th, 2021 - Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease; understanding ALS risk factors is a critical public health issue. To evaluate the incidence of and mortality from ALS in National Football League (NFL) athletes and to describe characteristics associated with ALS within this cohort. This population-based cohort study included all 19 423 NFL athletes who debuted between 19...

Mesenchymal stem cell extracellular vesicles mitigate vascular permeability and injury ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866219
The Journal of Trauma and Acute Care Surgery; Barry M, Trivedi A et. al.

Dec 10th, 2021 - Hemorrhagic shock and trauma (HS/T)-induced gut injury may play a critical role in the development of multi-organ failure. Novel therapies that target gut injury and vascular permeability early after HS/T could have substantial impacts on trauma patients. In this study, we investigate the therapeutic potential of human mesenchymal stem cells (MSCs) and MSC-derived extracellular vesicles (MSC EV...

A patient with Turner syndrome received the percutaneous vertebroplasty seven times: a ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650291
European Journal of Medical Research; Li L, Shi Y et. al.

Dec 9th, 2021 - Turner syndrome (TS) is characterized as the complete or partial absence of one X chromosome and is an extremely rare disease affecting approximately 1:2500 live female births. Though the prevalence of osteoporosis among women with TS is estimated to be around 55-64% and they suffer more frequently from fractures than normal, few reports concerning TS patients with osteoporosis are able to be s...

Kidney VISTA prevents IFN-γ/IL-9 axis-mediated tubulointerstitial fibrosis after acute ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718152
The Journal of Clinical Investigation; Kim MG, Yun D et. al.

Nov 10th, 2021 - Severe glomerular injury ultimately leads to tubulointerstitial fibrosis that determines patient outcome, but the immunological molecules connecting these processes remain undetermined. The present study addressed whether V-domain Ig suppressor of T cell activation (VISTA), constitutively expressed in kidney macrophages, plays a protective role in tubulointerstitial fibrotic transformation afte...

Use of bile acids as potential markers of liver dysfunction in humans: A systematic rev...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519223
Medicine Azer SA, Hasanato R

Nov 4th, 2021 - This study aimed to determine the effectiveness of using total, individual serum, or urinary bile acids (BA) as potential markers of liver dysfunction. We searched the PubMed and Web of Science databases using the following keywords- "serum bile acids," "liver dysfunction," "liver injury," "liver disease," "traditional liver function tests," "Chronic liver disease," "acute liver injury". The se...