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About 2,510 results

Primary lymphoma of the medial cutaneous nerve of the forearm: the first case in a pure...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8968523
BMJ Case Reports; De Vitis R, D'Orio M et. al.

Apr 1st, 2022 - Primary lymphoma of the peripheral nerve is very rare and occurs most frequently in sciatic nerves. We describe the first patient reported in literature with a primary lymphoma in a pure sensory peripheral nerve of the upper limb. A woman in her 40s, with painful swelling and dysaesthesias in her left forearm in the past 3 months, was presented at our unit. Clinical MRI and ultrasound findings ...

Sacral neuromodulation of bladder underactivity induced by prolonged pudendal afferent ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9076414
American Journal of Physiology. Regulatory, Integrative A... Shen B, Wang J et. al.

Mar 24th, 2022 - This study examined the effect of sacral neuromodulation on persistent bladder underactivity induced by prolonged pudendal nerve stimulation (PudNS). In 10 α-chloralose-anesthetized cats, repetitive application of 30-min PudNS induced bladder underactivity evident as an increase in bladder capacity during a cystometrogram (CMG). S1 or S2 dorsal root stimulation (15 or 30 Hz) at 1 or 1.5 times t...

A multidimensional facial surface EMG analysis for objective assessment of bulbar invol...
https://doi.org/10.1016/j.clinph.2021.11.074
Clinical Neurophysiology : Official Journal of the Intern... Rong P, Pattee GL

Jan 17th, 2022 - To develop a multidimensional facial surface electromyographic (EMG) analysis for assessing bulbar involvement in amyotrophic lateral sclerosis (ALS). Fifty-four linear and nonlinear features were extracted from the surface EMG recordings for masseter, temporalis, and anterior belly of digastric in 13 patients with ALS and 10 healthy controls, each performed a speech task three times. The featu...

Small fiber neuropathy for assessment of disease severity in amyotrophic lateral sclero...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734326
Orphanet Journal of Rare Diseases; Fu J, He J et. al.

Jan 8th, 2022 - Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with progressive motor system impairment, and recent evidence has identified the extra-motor involvement. Small fiber neuropathy reflecting by sensory and autonomic disturbances in ALS has been reported to accompany the motor damage. However, non-invasive assessment of this impairment and its application in disease evalua...

Impact of autoantibodies against the M2-muscarinic acetylcholine receptor on clinical o...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8713397
BMC Cardiovascular Disorders; Ma G, Chen L et. al.

Dec 30th, 2021 - To evaluate the impact of autoantibodies against the M2-muscarinic receptor (anti-M2-R) on the clinical outcomes of patients receiving the standard treatment for peripartum cardiomyopathy (PPCM). A total of 107 PPCM patients who received standard heart failure (HF) treatment between January 1998 and June 2020 were enrolled in this study. According to anti-M2-R reactivity, they were classified i...

Botulinum Toxin Type A for Lumbar Sympathetic Ganglion Block in Complex Regional Pain S...
https://doi.org/10.1097/ALN.0000000000004084
Anesthesiology Yoo Y, Lee CS et. al.

Dec 11th, 2021 - The present study was designed to test the hypothesis that botulinum toxin would prolong the duration of a lumbar sympathetic block measured through a sustained increase in skin temperature. The authors performed a randomized, double-blind, controlled trial to investigate the clinical outcome of botulinum toxin type A for lumbar sympathetic ganglion block in patients with complex regional pain ...

Corneal Neurotization Using the Great Auricular Nerve for Bilateral Congenital Trigemin...
https://doi.org/10.1097/ICO.0000000000002951
Cornea Lau N, Osborne SF et. al.

Nov 29th, 2021 - The purpose of this study was to describe an indirect corneal neurotization (CN) technique for congenital bilateral trigeminal anesthesia using the greater auricular nerve (GAN) as a donor. CN was performed to preserve the integrity of the only seeing eye in a 4-year-old boy with pontine tegmental cap dysplasia and bilateral trigeminal anesthesia. He had recurrent corneal ulceration and scarrin...

Aberrant enteric neuromuscular system and dysbiosis in amyotrophic lateral sclerosis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632307
Gut Microbes; Zhang Y, Ogbu D et. al.

Nov 24th, 2021 - Amyotrophic Lateral Sclerosis is a neuromuscular disease characterized by the progressive death of motor neurons and muscle atrophy. The gastrointestinal symptoms in ALS patients were largely ignored or underestimated. The relationship between the enteric neuromuscular system and microbiome in ALS progression is unknown. We performed longitudinal studies on the enteric neuron system (ENS) and m...

Gastroparesis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678360
Gastroenterology Camilleri M, Sanders KM

Nov 1st, 2021 - Gastroparesis is characterized by symptoms suggestive of, and objective evidence of, delayed gastric emptying in the absence of mechanical obstruction. This review addresses the normal emptying of solids and liquids from the stomach and details the myogenic and neuromuscular control mechanisms, including the specialized function of the pyloric sphincter, that result in normal emptying, based pr...

Transversus abdominis plane block provides effective and safe anesthesia in the cesarea...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556015
Medicine Wang Y, Zhang Y et. al.

Oct 30th, 2021 - Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with the fatal course of muscle weakness. The published experience of anesthesia management in the cesarean section with ALS parturient is scant. A 34-year-old woman was admitted to our center complaining of obvious dysphagia together with atrophy and weakness of quadriceps at 24 weeks of her pregnancy. Cesarean was ...

Reduced Corneal Sensitivity With Neuronal Degeneration is a Novel Clinical Feature in W...
https://doi.org/10.1016/j.ajo.2021.09.030
American Journal of Ophthalmology; Waszczykowska A, Zmysłowska A et. al.

Oct 29th, 2021 - To evaluate corneal sensitivity and corneal nerve morphology among patients with Wolfram syndrome (WFS). An observational clinical case series with confirmatory experiments. We included a group of 12 patients with biallelic mutations in the WFS1 gene and a control group composed of 30 individuals with type 1 diabetes (T1D). All participants (n = 42) underwent a complete ophthalmic examination, ...

Primary cutaneous adenoid cystic carcinoma of the skin with regional lymph node metasta...
https://doi.org/10.1684/ejd.2021.4125
European Journal of Dermatology : EJD; Sato Y, Tsunoda K et. al.

Oct 28th, 2021 - Primary cutaneous adenoid cystic carcinoma of the skin with regional lymph node metastasis.|2021|Sato Y,Tsunoda K,Sugai T,Amano H,|pathology,pathology,innervation,pathology,pathology,

Corneal Sensation and Nerve Fiber Changes in Patients With Interstitial Cystitis.
https://doi.org/10.1097/ICO.0000000000002887
Cornea Aykut V, Ucar IC et. al.

Oct 26th, 2021 - Central sensitization syndromes are associated with ocular surface discomfort and certain changes in corneal sensation. The aim of this study was to evaluate corneal changes in patients with interstitial cystitis (IC). Thirty patients with IC and 32 healthy control subjects were included in this study. All patients had a detailed ophthalmological examination including measurement of corneal sen...

Ixekizumab exposure associated with myelitis: A case report and a literature review.
https://doi.org/10.1016/j.jneuroim.2021.577726
Journal of Neuroimmunology; Romozzi M, Bellavia S et. al.

Oct 11th, 2021 - We describe a case of a 28-year-old man who developed a cervical myelitis while exposed to ixekizumab (IL-17 inhibitor) for psoriatic arthritis. Spinal MRI showed a T2 hyperintense lesion at the C4-C5 level while brain MRI was unspecific. Oligoclonal bands were absent and extensive screening for autoimmunity was negative. Rechallenge with ixekizumab was positive corroborating a relation between...

A case report of refractory otalgia after Ramsay Hunt syndrome successfully treated by ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483850
Medicine Kim YS, Son JS et. al.

Oct 2nd, 2021 - Ramsay Hunt syndrome is a type of herpes zoster infection involving geniculate ganglion and facial nerve. Unilateral facial palsy, otalgia, and painful vesicular rash on the auricle and external auditory canal are the typical symptoms. Although postherpetic neuralgia (PHN) is a devastating complication of herpes zoster infection, PHN following Ramsay Hunt syndrome has rarely been reported. A 55...

Middle ear myoclonus: Systematic review of results and complications for various treatm...
https://doi.org/10.1016/j.amjoto.2021.103228
American Journal of Otolaryngology; Wong WK, Lee MF

Sep 20th, 2021 - To perform a systematic review of the diagnosis and treatment of patients with pulsatile tinnitus secondary to middle ear myoclonus. PubMed, EMBASE, and Scopus. A systematic review was performed using standardized methodology. Computerized and manual searches were performed to identify studies of all ages (patients) who had middle ear myoclonus (intervention). All study designs were assessed. E...

Cutaneous pain in disorders affecting peripheral nerves.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579816
Neuroscience Letters; Stucky CL, Mikesell AR

Sep 11th, 2021 - Our ability to quickly detect and respond to harmful environmental stimuli is vital for our safety and survival. This inherent acute pain detection is a "gift" because it both protects our body from harm and allows healing of damaged tissues [1]. Damage to tissues from trauma or disease can result in distorted or amplified nociceptor signaling and sensitization of the spinal cord and brain (Cen...

Testing silicone digit extensions as a way to suppress natural sensation to evaluate su...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8410127
PloS One; Engels LF, Cappello L et. al.

Sep 2nd, 2021 - Dexterous use of the hands depends critically on sensory feedback, so it is generally agreed that functional supplementary feedback would greatly improve the use of hand prostheses. Much research still focuses on improving non-invasive feedback that could potentially become available to all prosthesis users. However, few studies on supplementary tactile feedback for hand prostheses demonstrated...

Corneal Nerve Fiber and Sensitivity Loss After Repeated Intravitreal Anti-VEGF Injectio...
https://doi.org/10.1097/ICO.0000000000002836
Cornea Polat OA, Şener H et. al.

Sep 2nd, 2021 - The purpose of this study was to investigate corneal sensation, subbasal nerve plexus (SBNP), and ocular surface symptoms in patients who underwent multiple intravitreal antivascular endothelial growth factor (anti-VEGF) injections for age-related macular degeneration (AMD) and diabetic macular edema (DME). Forty patients with previous anti-VEGF intravitreal injections (20 AMD and 20 DME) and 3...

Evaluation of Tp-e interval, Tp-e/QT ratio and index of cardiac-electrophysiological ba...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406962
BMC Cardiovascular Disorders; Kaya H, Suner A et. al.

Sep 1st, 2021 - Tinnitus is a common auditory symptom. Dysfunction in the autonomic nervous system (ANS) is an essential part of the etiopathogenesis of tinnitus. ANS regulates heart rate and heart rhythm and can lead to ventricular repolarization changes, which can cause malignant ventricular arrhythmias. T wave peak-to-end T(p-e) interval and T(p-e)/QT ratio are known ventricular arrhythmia indexes, and the ...