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About 2,358 results

Orexin contributes to eupnea within a critical period of postnatal development.
https://doi.org/10.1152/ajpregu.00156.2021
American Journal of Physiology. Regulatory, Integrative A... Spinieli RL, Ben Musa R et. al.

Aug 19th, 2021 - Orexin neurons are active in wakefulness and mostly silent in sleep. In adult rats and humans, orexin facilitates the hypercapnic ventilatory response but has little effect on resting ventilation. The influence of orexin on breathing in the early postnatal period, and across states of vigilance, have not been investigated. This is relevant as the orexin system may be impaired in Sudden Infant D...

Paradoxical response of pulmonary slowly adapting units during constant pressure lung i...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409913
American Journal of Physiology. Regulatory, Integrative A... Yu J

Jul 1st, 2021 - Typically, unit discharge of slowly adapting receptors (SARs) declines slowly when lung inflation pressure is constant, although in some units it increases instead-a phenomenon hereinafter referred to as creeping. These studies characterize creeping behavior observed in 62 of 137 SAR units examined in anesthetized, open-chest, and mechanically ventilated rabbits. SAR units recorded from the cer...

Long-term stable efficacy of botulinum toxin A in facial movement disorders with no nee...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238266
Medicine Badarny S, Ibrahim R et. al.

Jun 24th, 2021 - Botulinum toxin A is considered an effective treatment for involuntary facial movements. We examined whether treatment efficacy maintained or changed over time with two products, Botox and Dysport, in patients with hemifacial spasm, facial synkinesis and benign essential blepharospasm.We retrospectively investigated 87 consecutive patients (51 women, 36 men) who had undergone treatment for ≥6 y...

Arachnoid Cysts of the Internal Auditory Canal: Multiplanar Magnetic Resonance Imaging ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518068
The Laryngoscope; Di Stadio A, Dipietro L et. al.

Jun 22nd, 2021 - To investigate prevalence, radiological characteristics, and functional correlates of arachnoid cysts (AC) of the internal auditory canal (IAC) region, including associations of nerve compression with auditory/vestibular symptoms and asymmetrical audiogram or vestibular testing. Retrospective study. T2-weighted magnetic resonance imaging (MRI) studies of IACs were retrospectively analyzed from ...

Safety and efficacy of occipital nerve stimulation for attack prevention in medically i...
https://doi.org/10.1016/S1474-4422(21)00101-0
The Lancet. Neurology; Wilbrink LA, de Coo IF et. al.

Jun 20th, 2021 - Occipital nerve stimulation (ONS) has shown promising results in small uncontrolled trials in patients with medically intractable chronic cluster headache (MICCH). We aimed to establish whether ONS could serve as an effective treatment for patients with MICCH. The ONS in MICCH (ICON) study is an investigator-initiated, international, multicentre, randomised, double-blind, phase 3, electrical do...

Preoperative Differences in Intracranial Facial Versus Vestibular Schwannomas: A Four N...
https://doi.org/10.1002/lary.29628
The Laryngoscope; Erbele ID, Klumpp ML et. al.

May 21st, 2021 - Assesses whether preoperative functional testing can distinguish vestibular schwannomas from facial nerve schwannomas medial to the labyrinthine segment. Retrospective cohort. Retrospectively review surgically managed intracranial facial and vestibular schwannomas between January 2015 and December 2019 at two tertiary care centers. Patients with neurofibromatosis 2 and surgery for recurrence we...

What Is the Clinical Correlation of Cardiac Noradrenergic Denervation in Parkinson Dise...
https://doi.org/10.1212/WNL.0000000000011805
Neurology Lamotte G, Benarroch EE

May 11th, 2021 - What Is the Clinical Correlation of Cardiac Noradrenergic Denervation in Parkinson Disease?|2021|Lamotte G,Benarroch EE,|pathology,pathology,innervation,pathology,pathology,

Reactivation of SARS-CoV-2 after Rituximab in a Patient with Multiple Sclerosis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137054
Multiple Sclerosis and Related Disorders; Bose G, Galetta K

Apr 26th, 2021 - Nerve injury especially inferior alveolar nerve (IAN) is the one of the complications that occur when the mandibular third molar (M3) is extracted and in case of high risk patients, coronectomy might be an alternative to tooth extraction. The purpose of this retrospective study was to analyze root migration and its influencing factors at 6 months after coronectomy in both 2- and 3-dimensions us...

Dystypia Associated with Diaschisis of the Middle Frontal Gyri after Left Angular Infar...
https://doi.org/10.1016/j.jstrokecerebrovasdis.2021.105803
Journal of Stroke and Cerebrovascular Diseases : the Offi... Maeda K, Yamamoto Y et. al.

Apr 24th, 2021 - Dystypia without aphasia, agraphia, or apraxia is a rare symptom and has been suggested to result from a lesion in the left middle frontal cortex. We herein describe a man with dystypia with agraphia due to infarction of the left angular gyrus. His dystypia seemed to result from the convergence failure of the kana into the alphabetical spellings. During dystypia, hypoperfusion of the bilateral ...

Review of the Current Medical and Surgical Treatment Options for Microstomia in Patient...
https://doi.org/10.1097/DSS.0000000000002995
Dermatologic Surgery : Official Publication for American ... Gonzalez CD, Pamatmat JJ et. al.

Apr 20th, 2021 - Most patients with scleroderma suffer from microstomia, which can have debilitating consequences on their quality of life. Unfortunately, treatment options remain limited. No specific guidelines exist; hence, microstomia remains a challenge to treat in this patient population. This review aims to evaluate the different medical and surgical treatment modalities currently available for microstomi...

Sympathetic nerve outflow to skin in a case with dentatorubral-pallidoluysian atrophy.
https://doi.org/10.1016/j.jocn.2021.02.005
Journal of Clinical Neuroscience : Official Journal of Th... Shindo K, Sato T et. al.

Apr 18th, 2021 - Dentatorubral-pallidoluysian atrophy (DRPLA) is an autosomal dominant neurodegenerative disorder characterized by slowly progressive cerebellar ataxia. Previously, autonomic symptoms or dysfunction have not been reported. To evaluate subclinical autonomic dysfunction regarding thermoregulatory function in SCA, we recorded sympathetic outflow to skin in a DRPLA patient confirmed by genetic analy...

Reference values for lower limb nerve ultrasound and its diagnostic sensitivity.
https://doi.org/10.1016/j.jocn.2021.01.013
Journal of Clinical Neuroscience : Official Journal of Th... Niu J, Zhang L et. al.

Mar 30th, 2021 - We aimed to establish the cross-sectional area (CSA) reference values for peripheral nerves of lower extremities in a healthy Chinese population, and to determine their diagnostic values for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and Charcot-Marie-Tooth disease type1A (CMT1A). One hundred eleven healthy subjects, 15-70 years of age, as well as 104 CIDP patients and 26 ...

Advanced Therapies for Ventricular Arrhythmias in Patients With Chagasic Cardiomyopathy...
https://doi.org/10.1016/j.jacc.2020.12.056
Journal of the American College of Cardiology; Romero J, Velasco A et. al.

Mar 6th, 2021 - Chagas disease is caused by infection from the protozoan parasite Trypanosoma cruzi. Although it is endemic to Latin America, global migration has led to an increased incidence of Chagas in Europe, Asia, Australia, and North America. Following acute infection, up to 30% of patients will develop chronic Chagas disease, with most patients developing Chagasic cardiomyopathy. Chronic Chagas cardiom...

An organoid-based organ-repurposing approach to treat short bowel syndrome.
https://doi.org/10.1038/s41586-021-03247-2 10.1038/nature07935
Nature Sugimoto S, Kobayashi E et. al.

Feb 26th, 2021 - The small intestine is the main organ for nutrient absorption, and its extensive resection leads to malabsorption and wasting conditions referred to as short bowel syndrome (SBS). Organoid technology enables an efficient expansion of intestinal epithelium tissue in vitro1, but reconstruction of the whole small intestine, including the complex lymphovascular system, has remained challenging2. He...

OCT-angiography: Regional reduced macula microcirculation in ocular hypertensive and pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877568
PloS One; Hohberger B, Lucio M et. al.

Feb 12th, 2021 - OCT-angiography (OCT-A) offers a non-invasive method to visualize retinochoroidal microvasculature. As glaucoma disease affects retinal ganglion cells in the macula, macular microcirculation is of interest. The purpose of the study was to investigate regional macular vascular characteristics in patients with ocular hypertension (OHT), pre-perimetric primary open-angle glaucoma (pre-POAG) and co...

Relationship of motor mechanisms to gastroparesis symptoms: toward individualized treat...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238170
American Journal of Physiology. Gastrointestinal and Live... Camilleri M

Feb 11th, 2021 - Following a classical paper by Dr. Keith A. Kelly published in this journal, and over the past 40 years, there has been increased understanding of the functions of different regions of the stomach, specifically the fundus, antrum, and pylorus. Several of the important physiological principles were based on in vivo animal studies that led to the appreciation of regional function and control mech...

Does autonomic nervous system dysfunction influence cardiovascular disease risk in youn...
https://doi.org/10.1152/ajpheart.00807.2020
American Journal of Physiology. Heart and Circulatory Phy... Zwack CC, McDonald R et. al.

Feb 11th, 2021 - People with intellectual disability (ID) experience cardiometabolic-related morbidity and mortality. However, it has been suggested that this population presents and lives with underestimated cardiovascular risk factors at a younger age, hence affecting their overall health and quality of life and contributing to early mortality. We assessed autonomic nervous system function in subjects with ID...

Clinical characteristics of 93 cases of isolated macrodactyly of the foot in children.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869226
Journal of Orthopaedic Surgery and Research; Chen W, Tian X et. al.

Feb 10th, 2021 - The purpose of this study was to describe the clinical characteristics of macrodactyly of the foot through a large cohort of cases to further understand this rare entity. Medical records, clinical photographs, plain radiographs, pathological findings, and intraoperative photographs of 95 feet of 93 patients were reviewed. Data including age; sex; laterality; ethnicity; birthplace; family histor...

V180I genetic Creutzfeldt-Jakob disease with cardiac sympathetic nerve denervation masq...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808525
Medicine Fujita H, Ogaki K et. al.

Jan 21st, 2021 - Creutzfeldt-Jakob disease (CJD) with a point mutation of valine to isoleucine at codon 180 of the prion protein gene (V180I) is the most frequent form of genetic CJD in Japan. However, peripheral nerve involvement, especially cardiac sympathetic denervation, has not been investigated in cases with V180I genetic CJD.We herein report a genetically confirmed case of V180I genetic CJD presenting wi...

Anatomo-sonographic identification of the longissimus capitis and splenius cervicis mus...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164608
Surgical and Radiologic Anatomy : SRA; Brumpt E, Aubry S et. al.

Jan 19th, 2021 - The main objective of this study was to define and verify anatomo-sonographic landmarks for ultrasound-guided injection of botulinum toxin into the longissimus capitis (LC) and splenius cervicis (SC) muscles. After a preliminary work of anatomical description of the LC and SC muscles, we identified these muscles on two cadavers and then on a healthy volunteer using ultrasound and magnetic reson...