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About 14,395 results

Modified expi293 cell culture system using piggyBac transposon enables efficient produc...
https://doi.org/10.1007/s12185-022-03468-9
International Journal of Hematology; Yoshimura T, Horiuchi K et. al.

Oct 14th, 2022 - Human blood coagulation factor VIII (hFVIII) is used in hemostatic and prophylactic treatment of patients with hemophilia A. Biotechnological innovations have enabled purification of the culture medium of rodent or human cells harboring the hFVIII expression cassette. However, cell lines express hFVIII protein derived from an exogenous expression vector at a lower level than most other proteins...

Apple Watch Parkinson Disease Symptom Monitor Is Cleared.
https://doi.org/10.1001/jama.2022.12641
JAMA Larkin HD

Aug 3rd, 2022 - Apple Watch Parkinson Disease Symptom Monitor Is Cleared.|2022|Larkin HD,|instrumentation,diagnosis,instrumentation,

Adaptive wireless millirobotic locomotion into distal vasculature.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343456
Nature Communications; Wang T, Ugurlu H et. al.

Aug 2nd, 2022 - Microcatheters have enabled diverse minimally invasive endovascular operations and notable health benefits compared with open surgeries. However, with tortuous routes far from the arterial puncture site, the distal vascular regions remain challenging for safe catheter access. Therefore, we propose a wireless stent-shaped magnetic soft robot to be deployed, actively navigated, used for medical f...

Outcomes after gamma knife radiosurgery for intraventricular meningiomas.
https://doi.org/10.1007/s11060-022-04091-8
Journal of Neuro-oncology; Daza-Ovalle A, Bin-Alamer O et. al.

Jul 27th, 2022 - Intraventricular meningiomas (IVMs) are rare tumors with considerable treatment-associated morbidity due to their challenging location. Treatment with stereotactic radiosurgery (SRS) is sparsely reported in the literature. We describe our experience over the last 35 years using Gamma knife radiosurgery (GKRS) for IVMs. We retrospectively reviewed the GKRS database identifying 2501 meningiomas t...

Hydrocephalus Study Design: Testing New Hypotheses in Clinical Studies and Bench-to-Bed...
https://doi.org/10.1016/j.wneu.2021.12.100
World Neurosurgery; Juhler M, Hansen TS et. al.

May 5th, 2022 - In this article, we aimed to describe some of the currently most challenging problems in neurosurgical management of hydrocephalus and how these can be reasons for inspiration for and development of research. We chose 4 areas of focus: 2 dedicated to improvement of current treatments (shunt implant surgery and endoscopic hydrocephalus surgery) and 2 dedicated to emerging future treatment princi...

Dynamic Standing Exercise using the Innowalk Device in Patients with Genetic and Acquir...
https://doi.org/10.2340/jrm.v54.23
Journal of Rehabilitation Medicine; Pekanovic A, Strobl W et. al.

Apr 2nd, 2022 - For individuals with motor impairments, dynamic standing has been proposed as an opportunity for regular daily physical activity. The aim of this study was to analyse patient characteristics, indications, intensity of usage, desired objectives and outcomes of dynamic standing in daily clinical practice in order to form the basis for research regarding this treatment option. Data were analysed f...

Professional practice for COVID-19 risk reduction among health care workers: A cross-se...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936447
PloS One; Wilson S, Mouet A et. al.

Mar 22nd, 2022 - Health care workers (HCWs) are particularly exposed to COVID-19 and therefore it is important to study preventive measures in this population. To investigate socio-demographic factors and professional practice associated with the risk of COVID-19 among HCWs in health establishments in Normandy, France. A cross-sectional and 3 case-control studies using bootstrap methods were conducted in order ...

Sex-Specific Difference in Outcomes after Transcatheter Mitral Valve Repair with MitraC...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885186
Journal of Interventional Cardiology; Sun F, Liu H et. al.

Mar 15th, 2022 - Implantation of the MitraClip is a safe and effective therapy for mitral valve repair in patients ineligible for surgery or at high risk of adverse surgical outcomes. However, only limited information is available concerning sex differences in transcatheter mitral valve repair. We therefore sought to conduct a comprehensive meta-analysis of studies that investigated differences between men and ...

Rarely Described Renal Malignancies Associated With Venous Tumor Thrombus.
https://doi.org/10.21873/anticanres.15604
Anticancer Research; Velasquez MC, Mouzannar A et. al.

Feb 28th, 2022 - Collecting duct carcinoma, epithelioid angiosarcoma and neuroendocrine/carcinoid tumor are uncommon renal malignancies, and their association with tumor thrombus extending into the inferior vena cava is extremely rare. Owing to the rarity of the above-mentioned malignancies and short follow-up of the cases published in the literature, the prognosis and clinical behavior of these tumors remains ...

Infection Prevention during the Coronavirus Disease 2019 Pandemic.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837397
Infectious Disease Clinics of North America; Reich P, Elward A

Feb 17th, 2022 - COVID-19 is a nonspecific viral illness caused by a novel coronavirus, SARS-CoV-2, and led to an ongoing global pandemic. Transmission is primarily human-to-human via contact with respiratory particles containing infectious virus. The risk of transmission to health care personnel is low with proper use of personal protective equipment, including gowns, gloves, N95 or surgical mask, and eye prot...

Investigation of respiratory rate in patients with cystic fibrosis using a minimal-impa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8832687
BMC Pulmonary Medicine; Straßburg S, Linker CM et. al.

Feb 13th, 2022 - In this study we tested the hypothesis that in patients with cystic fibrosis (pwCF) respiratory rate (RR) is associated with antibiotic treatment, exacerbation status, forced expiratory volume in one second (FEV1) and C-reactive protein (CRP). Between June 2018 and May 2019, we consecutively enrolled pwCF who were referred to our hospital. We determined RR and heart rate (HR) by using the minim...

Transcatheter Mitral Valve Edge-to-Edge Repair with a Novel System.
https://doi.org/10.1536/ihj.21-225
International Heart Journal; Long Y, Pan W et. al.

Feb 1st, 2022 - The ValveClamp system is a novel edge-to-edge mitral valve repair system that is designed for ease of operation. We aimed to report the 1-year outcomes of the early feasibility study of this system.Patients with severe degenerative mitral regurgitation (MR) at higher surgical risk and who received transapical ValveClamp implantation were followed for 1 year for clinical and echocardiographic ou...

Pre-pectoral Immediate Breast Reconstruction Following Conservative Mastectomy Using Ac...
https://doi.org/10.21873/anticanres.15562
Anticancer Research; Wazir U, Patani N et. al.

Jan 31st, 2022 - Improvements in acellular dermal matrix (ADM) and surgical techniques have facilitated pre-pectoral immediate breast reconstruction (IBR). Outer shell texturing is a key risk factor for anaplastic large cell lymphoma, prompting this evaluation of reconstruction with nano-textured rounded implants. Fifty-one consecutive patients underwent 72 pre-pectoral ADM-assisted (fenestrated SurgiMend™) IBR...

Identification of parameters and formulation of a statistical and machine learning mode...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801090
Parasites & Vectors; Pijnacker T, Bartels R et. al.

Jan 31st, 2022 - Canine babesiosis is an important tick-borne disease in endemic regions. One of the relevant subspecies in Europe is Babesia canis, and it can cause severe clinical signs such as hemolytic anemia. Apart from acute clinical symptoms dogs can also have a more chronic disease development or be asymptomatic carriers. Our objective was to identify readily available ADVIA hematology analyzer paramete...

Occupational dose and associated factors during transarterial chemoembolization of hepa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797565
Medicine Kim HO, Lee BC et. al.

Jan 29th, 2022 - Transarterial chemoembolization is the standard treatment option for intermediate-stage hepatocellular carcinoma (HCC). However, during the interventional procedure, occupational radiation protection is compromised. The use of real-time radiation dosimetry could provide instantaneous radiation doses. This study aimed to evaluate the occupational dose of the medical staff using a real-time radia...

Simultaneous perception of prosthetic and natural vision in AMD patients.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792035
Nature Communications; Palanker D, Le Mer Y et. al.

Jan 28th, 2022 - Loss of photoreceptors in atrophic age-related macular degeneration (AMD) results in severe visual impairment. Since the low-resolution peripheral vision is retained in such conditions, restoration of central vision should not jeopardize the surrounding healthy retina and allow for simultaneous use of the natural and prosthetic sight. This interim report, prespecified in the study protocol, pre...

End-to-end system for rapid and sensitive early-detection of SARS-CoV-2 for resource-po...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791454
PloS One; Lin EE, Razzaque UA et. al.

Jan 27th, 2022 - COVID-19 has exposed stark inequalities between resource-rich and resource-poor countries. International UN- and WHO-led efforts, such as COVAX, have provided SARS-CoV-2 vaccines but half of African countries have less than 2% vaccinated in their population, and only 15 have reached 10% by October 2021, further disadvantaging local economic recovery. Key for this implementation and preventing f...

Using social media to crowdsource collection of urine samples during a national pandemic.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790544
International Urology and Nephrology; Ward EP, Bartolone SN et. al.

Jan 27th, 2022 - The COVID-19 pandemic and subsequent lockdown had a substantial impact on normal research operations. Researchers needed to adapt their methods to engage at-home participants. One method is crowdsourcing, in which researchers use social media to recruit participants, gather data, and collect samples. We utilized this method to develop a diagnostic test for Interstitial Cystitis/Bladder Pain Syn...

Mycobacterium abscessus drug discovery using machine learning.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855326
Tuberculosis (Edinburgh, Scotland); Schmalstig AA, Zorn KM et. al.

Jan 26th, 2022 - The prevalence of infections by nontuberculous mycobacteria is increasing, having surpassed tuberculosis in the United States and much of the developed world. Nontuberculous mycobacteria occur naturally in the environment and are a significant problem for patients with underlying lung diseases such as bronchiectasis, chronic obstructive pulmonary disease, and cystic fibrosis. Current treatment ...

The 3-Dimensional-Computed Tomography Texture Is Useful to Predict Pancreatic Neuroendo...
https://doi.org/10.1097/MPA.0000000000001927
Pancreas Ricci C, Mosconi C et. al.

Jan 19th, 2022 - The aim of this study is to evaluate the computed tomography texture parameters in predicting grading. This study analyzed 68 nonfunctioning pancreatic neuroendocrine neoplasms (Pan-NENs). Clinical and radiological parameters were studied. Four model models were built, including clinical and standard radiologic parameters (model 1), first- and second-order computed tomography features (models 2...