About 1,058,473 results

Concomitant disease should be considered when treating progressive glaucoma

Jan 20th, 2022 - WAIKOLOA, Hawaii — Ophthalmologists should consider co-management of other diseases when treating progressive glaucoma, according to a speaker here. “I think that we need to remind ourselves, even as we rush through clinic, to think about the linkage to common disease that puts the optic nerve at risk,” Jeffrey L. Goldberg, MD, PhD, said at Hawaiian Eye 2022. To aid with co-management, he said,...

Chang highlights new trends in antibiotic prophylaxis for endophthalmitis

Jan 18th, 2022 - WAIKOLOA, Hawaii — Just past the 15-year anniversary of the cefuroxime ESCRS trial, debate regarding antibiotic prophylaxis for endophthalmitis after cataract surgery continues. “When you have something controversial, it's nice to see what our colleagues are doing,” David F. Chang, MD, said at Hawaiian Eye 2022. To that end, surveys of ASCRS members conducted in 2007, 2014 and 2021 published in...

How to avoid the perils of uveitis diagnostic management

Jan 16th, 2022 - WAIKOLOA, Hawaii — It is important for physicians to consider “the perils that dwell” in the diagnostic management of patients with uveitis, Steven Yeh, MD, said during a presentation at Hawaiian Eye 2022. “With these patients being very complex oftentimes, we really just don’t want to miss something,” Yeh said. To better identify “the pearls amongst the perils” in uveitis diagnosis, it is impo...

A Study to Evaluate Subcutaneous Daratumumab in Combination With Standard Multiple Myeloma Treatment Regimens

Jun 21st, 2022 - The hypothesis is that the addition of daratumumab administered SC to standard MM regimens will improve responses compared to response data observed in completed phase 3 studies without daratumumab. Disease evaluations will include measurements of myeloma proteins, bone marrow examinations, skeletal surveys, assessment of extramedullary plasmacytomas, and measurements of serum calcium corrected...

Natural History and Development of Spondyloarthritis

Jun 24th, 2022 - The purpose of this protocol is to study the natural history of spondyloarthritis (SpA) in children and adults. Spondyloarthritis encompasses a spectrum of immune-mediated inflammatory diseases that exhibit overlapping features, but differ from other types of inflammatory arthritis in genetic predisposition, pathogenesis, and outcome. Ankylosing spondylitis (AS), the most common form of SpA, fr...

The impact of a structured weight-loss treatment on physical fitness in patients with p...
https://doi.org/10.1007/s10067-022-06164-5 10.1056/NEJMra1505557 10.1111/1756-185X.12283 10.1093/rheumatology/ker349 10.1080/03009742.2019.1672783 10.3899/jrheum.171034 10.2174/1574887113666180314105511 10.1136/annrheumdis-2014-206824 10.1161/CIRCRESAHA.115.306883 10.1016/j.mayocp.2018.01.016 10.1007/s11695-013-0924-0 10.1016/S0140-6736(16)00271-3 10.1046/j.1467-789x.2001.00026.x 10.1249/MSS.0000000000001074 10.1111/obr.12422 10.1016/j.archger.2016.02.004 10.1016/j.physio.2015.05.003 10.1136/ard.51.1.35 10.1186/s13075-019-1810-5 10.1186/s13075-020-02350-5 10.1002/art.21972 10.3109/03009749309095105 10.1016/0002-9343(85)90465-6 10.1152/jappl.1954.7.2.218 10.1186/1471-2474-15-305 10.1097/00005650-199206000-00002 10.1111/sms.12611 10.1002/art.23568 10.1136/ard.2009.122259 10.1146/annurev.nutr.21.1.323 10.1002/oby.22476 10.1016/j.bone.2009.10.013 10.1002/art.33394 10.1001/jama.2009.681 10.1080/00913847.2019.1623995 10.1016/j.semarthrit.2004.07.010 10.3945/an.116.014506 10.1007/s11926-012-0263-5 10.1002/acr.24126 10.7762/cnr.2019.8.2.148 10.1186/s12905-019-0864-5
Clinical Rheumatology; Bilberg A, Larsson I et. al.

Jun 2nd, 2022 - To evaluate the effects of weight loss treatment on physical fitness in patients with psoriatic arthritis (PsA) and obesity compared to matched controls. In total, 46 patients with PsA (CASPAR) and BMI ≥ 33 kg/m2 and 52 obese persons were included in this 12-month prospective open intervention study with a very low energy diet (640 kcal/day), followed by structured reintroduction of an energy-r...

2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis.
Arthritis & Rheumatology (Hoboken, N.J.); Fraenkel L, Bathon JM et. al.

Jun 9th, 2021 - To develop updated guidelines for the pharmacologic management of rheumatoid arthritis. We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to rate the certainty of evidence. A voting panel comprising c...

Fluconazole - fluconazole tablet-REMEDYREPACK INC.

Dec 30th, 2022 - Fluconazole tablets are indicated for the treatment of: Vaginal candidiasis (vaginal yeast infections due to Candida). Oropharyngeal and esophageal candidiasis. In open noncomparative studies of relatively small numbers of patients, fluconazole tablets were also effective for the treatment of Candida urinary tract infections, peritonitis, and systemic Candida infections including candidemia, di...

Clues to Long COVID
Science Couzin-Frankel J.

Jun 16th, 2022 - They span three continents, but a trio of researchers who’ve never met share a singular focus made vital by the still-raging pandemic: deciphering the causes of Long Covid and figuring out how to treat it. Almost 2 years ago in Italy, pediatric infectious disease doctor Danilo Buonsenso, who works at Gemelli University Hospital, started to see children who, months after mild infections with ...

Risk factors for SARS-CoV-2 infection and transmission in households with asthmatic and allergic children. A prospective surveillance study
The Journal of Allergy and Clinical Immunology; Seibold MA, .

May 31st, 2022 - Whether children and people with asthma and allergic diseases are at increased risk for SARS-CoV-2 infection is unknown.

TG Therapeutics Announces Voluntary Withdrawal of the BLA/sNDA for U2 to Treat Patients with CLL and SLL
TG Therapeutics

Apr 15th, 2022 - NEW YORK, April 15, 2022 (GLOBE NEWSWIRE) -- TG Therapeutics, Inc. (NASDAQ: TGTX), today announced that the Company has voluntarily withdrawn the pending Biologics License Application (BLA)/supplemental New Drug Application (sNDA) for the combination of ublituximab and UKONIQ® (umbralisib) (combination referred to as U2) for the treatment of adult patients with chronic lymphocytic leukemia (CLL...

Ambient air pollution and COVID-19 risk: Evidence from 35 observational studies
Environmental Research; Zang ST, .

Mar 30th, 2022 - Coronavirus disease 2019 (COVID-19) is induced by a previously undiscovered coronavirus, designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Lu et al., 2020). Since SARS-CoV-2 was first discovered in December 2019, as of April 25, 2021, more than four million fatalities have been attributed to COVID-19, accounting for approximately 2% of the infected cases (>214 million)...

WHO consolidated guidelines on tuberculosis Module 5: Management of tuberculosis in children and adolescents
World Health Organization (WHO)

Mar 21st, 2022 - The Updated guidelines on Management of tuberculosis in children and adolescents include new recommendations that cover diagnostic approaches for TB, shorter treatment for children with non-severe drug-susceptible TB, a new option for the treatment of TB meningitis, the use of bedaquiline and delamanid in young children with multidrug- and rifampicin-resistant TB and decentralized and family-ce...

FDA Roundup: July 1, 2022 | FDA

Jul 1st, 2022 - For Immediate Release: July 01, 2022 Today, the U.S. Food and Drug Administration is providing an at-a-glance summary of news from around the agency: Today, the FDA announced a request for nominations for consumer representatives to serve on advisory committees and panels for which vacancies currently exist or are expected to occur in the near future. The FDA relies on our many advisory committ...

Termination of pregnancy for medical reasons: A mental health perspective
Amelia Wendt, MD, Mary Shickich, MD et. al.

Jul 1st, 2022 - Termination of pregnancy for medical reasons (TFMR) occurs when a pregnancy is ended due to medical complications that threaten the health of a pregnant individual and/or fetus, or when a fetus has a poor prognosis or life-limiting diagnosis. It is distinct from the American College of Obstetricians and Gynecologists identification of all abortions as medically indicated.

Why we should be scrutinizing the rising prevalence of adult ADHD
Hashem N. Akbar, MD

Jul 1st, 2022 - In patients with attention-deficit/hyperactivity disorder (ADHD), stimulants reduce impulsivity and improve attention and focus. In individuals who do not have this disorder, stimulants are believed to enhance cognition, attention, and physical performance.

Then and now: A ‘lifetime’ of advancement in upper GI
David A. Katzka, MD, MDedge News

Jul 1st, 2022 - Fifteen years is a lifetime for the advancement of medical research. This seems particularly true for upper GI tract disorders.

Exocrine Pancreatic Insufficiency: Risk Factors and Management Approaches
Jodie Barkin, MD,, MDedge News

Jul 1st, 2022 - What characteristics or symptoms do you look for to identify patients who are at risk for exocrine pancreatic insufficiency (EPI)? Dr. Barkin: The first thing we have to understand is which patient populations we should consider.

Bimatoprost - bimatoprost solution/ drops-Lupin Pharmaceuticals, Inc.

Jul 1st, 2022 - Bimatoprost ophthalmic solution, 0.03% is a prostaglandin analog indicated for the reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension. (1) Bimatoprost ophthalmic solution, 0.03% is indicated for the reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension.


Jul 1st, 2022 - Practice Essentials In 1970, when smallpox was nearly eradicated, a previously unrecognized orthopoxvirus named monkeypox was identified in humans. The first known human case occurred in the Equateur province of Zaire (now known as the Democratic Republic of Congo [DRC]) when a 9-year-old boy developed a smallpoxlike illness, which was eventually confirmed as human monkeypox by the World Health...