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About 274,778 results

Ultrasonography of the colon in pediatric ulcerative colitis: a prospective, blind, com...
https://doi.org/10.1016/j.jpeds.2014.02.055
The Journal of Pediatrics; Civitelli F, Di Nardo G et. al.

Apr 14th, 2014 - To evaluate the usefulness of colonic ultrasonography (US) in assessing the extent and activity of disease in pediatric ulcerative colitis (UC) and to compare US findings with clinical and endoscopic features. Consecutive pediatric patients (n = 60) with a diagnosis of UC and suspected disease flare-up were prospectively enrolled; of these, 50 patients were eligible for the study. All underwent...

Nonmyeloablative HLA-matched sibling allogeneic hematopoietic stem cell transplantation...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698790
JAMA Hsieh MM, Fitzhugh CD et. al.

Jul 24th, 2014 - Myeloablative allogeneic hematopoietic stem cell transplantation (HSCT) is curative for children with severe sickle cell disease, but toxicity may be prohibitive for adults. Nonmyeloablative transplantation has been attempted with degrees of preparative regimen intensity, but graft rejection and graft-vs-host disease remain significant. To determine the efficacy, safety, and outcome on end-orga...

Actionable diagnosis of neuroleptospirosis by next-generation sequencing.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134948
The New England Journal of Medicine; Wilson MR, Naccache SN et. al.

Jun 4th, 2014 - A 14-year-old boy with severe combined immunodeficiency presented three times to a medical facility over a period of 4 months with fever and headache that progressed to hydrocephalus and status epilepticus necessitating a medically induced coma. Diagnostic workup including brain biopsy was unrevealing. Unbiased next-generation sequencing of the cerebrospinal fluid identified 475 of 3,063,784 se...

Pediatric mycosis fungoides in Singapore: a series of 46 children.
https://doi.org/10.1111/pde.12352
Pediatric Dermatology; Heng YK, Koh MJ et. al.

Jun 3rd, 2014 - Few studies have evaluated Asian children with mycosis fungoides (MF). We report a series of patients from a tertiary dermatologic institution in Singapore. A retrospective review was performed of patients younger than 16 years old diagnosed with MF between 2000 and 2008 at the National Skin Centre, Singapore. Forty-six patients were identified. At initial presentation, a provisional diagnosis ...

Early lung ultrasonography predicts the occurrence of acute respiratory distress syndro...
https://doi.org/10.1007/s00134-014-3382-9
Intensive Care Medicine; Leblanc D, Bouvet C et. al.

Jul 15th, 2014 - Extent of lung contusion on initial computed tomography (CT) scan predicts the occurrence of acute respiratory distress syndrome (ARDS) in blunt chest trauma patients. We hypothesized that lung ultrasonography (LUS) on admission could also predict subsequent ARDS. Forty-five blunt trauma patients were prospectively studied. Clinical examination, chest radiography, and LUS were performed on arri...

Review article: the management of portal hypertensive gastropathy and gastric antral va...
https://doi.org/10.1111/apt.12824
Alimentary Pharmacology & Therapeutics; Patwardhan VR, Cardenas A

Jun 3rd, 2014 - Portal hypertensive gastropathy (PHG) and gastric antral vascular ectasia (GAVE) are important causes of both acute and chronic gastrointestinal bleeding in patients with cirrhosis. To review the current management of PHG and GAVE. PubMed was searched for English language articles using the key words 'GAVE', 'gastric antral vascular ectasia', 'cirrhosis', 'gastrointestinal bleeding', 'acute', '...

Vulvar cancers in women with vulvar lichen planus: a clinicopathological study.
https://doi.org/10.1016/j.jaad.2014.05.057
Journal of the American Academy of Dermatology; Regauer S, Reich O et. al.

Jul 7th, 2014 - Vulvar squamous cell carcinomas (SCCs) arising in association with vulvar lichen planus (LP) are poorly documented. We sought to present clinicopathological features of 38 patients (median age 61 years, range 39-90 years) with LP-associated vulvar SCCs. Evaluated were location of vulvar SCC and metastases at presentation, recurrences, survival, precursor lesions, presence of human papillomaviru...

Causes of pulmonary hypertension in the elderly.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077408
Chest Pugh ME, Sivarajan L et. al.

Jan 31st, 2014 - Pulmonary hypertension (PH) is common in elderly patients, but a detailed analysis of the causes of PH in the elderly has not been performed. We hypothesized that pulmonary arterial hypertension (PAH) is rare in elderly patients and sought to describe the characteristics of these patients at a large referral center. Clinical and hemodynamic data were collected on consecutive patients ≥ 65 years...

Treatment-resistant bipolar depression: a randomized controlled trial of electroconvuls...
https://doi.org/10.1176/appi.ajp.2014.13111517
The American Journal of Psychiatry; Schoeyen HK, Kessler U et. al.

Sep 15th, 2014 - Electroconvulsive therapy (ECT) is regarded by many clinicians as the most effective treatment for treatment-resistant bipolar depression, but no randomized controlled trials have been conducted, to the authors' knowledge. They compared efficacy measures of ECT and algorithm-based pharmacological treatment in treatment-resistant bipolar depression. This multicenter, randomized controlled trial ...

Dietary elimination therapy is an effective option for adults with eosinophilic esophag...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102669
Clinical Gastroenterology and Hepatology : the Official C... Wolf WA, Jerath MR et. al.

Jan 20th, 2014 - Eosinophilic esophagitis (EoE) is an immune-mediated disorder. Food elimination is an established treatment for children, but data in adults are limited. We aimed to determine the response of adults with EoE to dietary therapy. This was a retrospective cohort study using the University of North Carolina EoE database from 2006 to 2012. Subjects were age 18 and older, had EoE by consensus guideli...

Prevalence of small-bowel neoplasia in Lynch syndrome assessed by video capsule endoscopy.
https://doi.org/10.1136/gutjnl-2014-307348
Gut Haanstra JF, Al-Toma A et. al.

Sep 11th, 2014 - The aim was to determine the prevalence of small-bowel neoplasia in asymptomatic patients with Lynch syndrome (LS) by video capsule endoscopy (VCE). After obtaining informed consent, asymptomatic proven gene mutation carriers aged 35-70 years were included in this prospective multicentre study in the Netherlands. Patients with previous small-bowel surgery were excluded. After bowel preparation,...

Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associate...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455597
Journal of Clinical Oncology : Official Journal of the Am... Kochenderfer JN, Somerville RPT et. al.

Mar 15th, 2017 - Purpose T cells genetically modified to express chimeric antigen receptors (CARs) targeting CD19 (CAR-19) have potent activity against acute lymphoblastic leukemia, but fewer results supporting treatment of lymphoma with CAR-19 T cells have been published. Patients with lymphoma that is chemotherapy refractory or relapsed after autologous stem-cell transplantation have a grim prognosis, and new...

Long-term results and recurrence patterns from SCALOP: a phase II randomised trial of g...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482737
British Journal of Cancer; Hurt CN, Falk S et. al.

Apr 4th, 2017 - SCALOP, a randomised, phase II trial, tested the activity and safety of gemcitabine (GEM)-based and capecitabine (CAP)-based chemoradiation (CRT) for locally advanced pancreatic cancer (LAPC). Here we present the long-term outcomes. Eligibility: histologically proven LAPC ⩽7 cm. Following 12 weeks of induction GEMCAP chemotherapy (three cycles: GEM 1000 mg m-2 days 1, 8, 15; CAP 830 mg m-2 days...

Renal Functional Outcomes after Surgery, Ablation, and Active Surveillance of Localized...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498358
Clinical Journal of the American Society of Nephrology : ... Patel HD, Pierorazio PM et. al.

May 9th, 2017 - Management strategies for localized renal masses suspicious for renal cell carcinoma include radical nephrectomy, partial nephrectomy, thermal ablation, and active surveillance. Given favorable survival outcomes across strategies, renal preservation is often of paramount concern. To inform clinical decision making, we performed a systematic review and meta-analysis of studies comparing renal fu...

Microwave ablation of malignant renal tumours: intermediate-term results and usefulness...
https://doi.org/10.1007/s12032-017-0948-8
Medical Oncology (Northwood, London, England); Ierardi AM, Puliti A et. al.

Apr 19th, 2017 - The aim of this study was to evaluate intermediate-term results after microwave ablation (MWA) of renal tumours and determine the association of RENAL and modified RENAL (mRENAL) scores with oncological outcomes and complications. In May 2008-September 2014, 58 patients affected by early-stage RCC (renal cell carcinoma; T1a or T1b) were judged unsuitable for surgery and treated with percutaneou...

Liver and combined lung and liver transplantation for cystic fibrosis: analysis of the ...
https://doi.org/10.1111/j.1399-3046.2010.01460.x
Pediatric Transplantation; Arnon R, Annunziato RA et. al.

Jan 11th, 2011 - A proportion of patients with CF develop cirrhosis and portal hypertension. LT and combined LLT are rarely performed in patients with CF. To determine the outcome of LT and LLT in patients with CF. Patients with CF who had LT or LLT between 10/1987 and 5/2008 were identified from UNOS database. A total of 182 children (<18 yr) and 48 adults underwent isolated LT for CF. Seven more children and ...

Moving toward "laboratory-supported" criteria for psychogenic tremor.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664413
Movement Disorders : Official Journal of the Movement Dis... Schwingenschuh P, Katschnig P et. al.

Sep 30th, 2011 - A confident clinical diagnosis of psychogenic tremor is often possible, but, in some cases, a "laboratory-supported" level of certainty would aid in early positive diagnosis. Various electrophysiological tests have been suggested to identify patients with psychogenic tremor, but their diagnostic reliability has never been assessed "head to head" nor compared to forms of organic tremor other tha...

Guidelines for the management of vitiligo: the European Dermatology Forum consensus.
https://doi.org/10.1111/j.1365-2133.2012.11197.x
The British Journal of Dermatology; Taieb A, Alomar A et. al.

Aug 6th, 2012 - The aetiopathogenic mechanisms of vitiligo are still poorly understood, and this has held back progress in diagnosis and treatment. Up until now, treatment guidelines have existed at national levels, but no common European viewpoint has emerged. This guideline for the treatment of segmental and nonsegmental vitiligo has been developed by the members of the Vitiligo European Task Force and other...

Long-term outcomes of pediatric living donor liver transplantation at a single institut...
https://doi.org/10.1111/j.1399-3046.2010.01357.x
Pediatric Transplantation; Oh SH, Kim KM et. al.

Jul 8th, 2010 - There have only been a few studies on the long-term outcomes and prognostic factors after pediatric LDLT. We conducted a retrospective, single-center assessment of the outcomes as well as the demographic and clinical factors that influenced the poor outcomes in 113 children aged <16 (median age 21 months; 6 months-15.5 yr) who underwent 115 LDLTs, predominantly for biliary atresia (60.9%) and F...

Endoscopic findings in patients with Schatzki rings: evidence for an association with e...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531680
World Journal of Gastroenterology; Müller M, Eckardt AJ et. al.

Jan 16th, 2013 - To investigate endoscopic findings in patients with Schatzki rings (SRs) with a focus on evidence for eosinophilic esophagitis (EoE). We consecutively approached all adult patients scheduled for elective outpatient upper endoscopy for a variety of indications at the German Diagnostic Clinic, Wiesbaden, Germany between July 2007 and July 2010. All patients with endoscopically diagnosed SRs, defi...