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About 46,775 results

Severe polymicrobial and fungal periprosthetic osteomyelitis persisting after hip disar...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720203
Annals of Clinical Microbiology and Antimicrobials; Enz A, Müller S et. al.

Jan 2nd, 2022 - Periprosthetic fungal infections are considered rare and opportunistic infections. Treatment is difficult, and established standards do not yet exist. The choice of the appropriate antifungal drug might affect the patient outcome. All the three cases presented showed polybacterial recurrent infection of the revision hip arthroplasty. All patients were of younger age, had multiple revisions of t...

Alteration of the gut microbiota following SARS-CoV-2 infection correlates with disease...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726722
Gut Microbes; Sencio V, Machelart A et. al.

Dec 30th, 2021 - Mounting evidence suggests that the gut-to-lung axis is critical during respiratory viral infections. We herein hypothesized that disruption of gut homeostasis during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may associate with early disease outcomes. To address this question, we took advantage of the Syrian hamster model. Our data confirmed that this model recapitu...

Diagnostic accuracy of Truenat Tuberculosis and Rifampicin-Resistance assays in Addis A...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714111
PloS One; Meaza A, Tesfaye E et. al.

Dec 29th, 2021 - Rapid and sensitive Tuberculosis (TB) diagnosis closer to patients is a key global TB control priority. Truenat assays (MTB, MTB Plus, and MTB-RIF Dx) are new TB molecular diagnostic tools for the detection of TB and Rifampicin (RIF)-resistance from sputum samples. The diagnostic accuracy of the assays is needed prior to implementation in clinical use in Ethiopia. This study aimed to determine ...

Allergic bronchopulmonary aspergillosis with chest pain as atypical symptoms.
https://doi.org/10.1016/S1473-3099(21)00423-0
The Lancet. Infectious Diseases; Chen TT, Zhou P et. al.

Dec 27th, 2021 - Allergic bronchopulmonary aspergillosis with chest pain as atypical symptoms.|2021|Chen TT,Zhou P,Nie L,Lei Y,Li D,|therapeutic use,diagnostic imaging,drug therapy,drug effects,pathogenicity,microbiology,

A new treatment for drug-resistant tuberculosis in Ukraine.
https://doi.org/10.1016/S1473-3099(21)00772-6
The Lancet. Infectious Diseases; Holt E

Dec 27th, 2021 - A new treatment for drug-resistant tuberculosis in Ukraine.|2021|Holt E,|administration & dosage,therapeutic use,drug effects,drug therapy,epidemiology,microbiology,epidemiology,

Possible relationship between esophageal dilatation and severity of M. abscessus pulmon...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699664
PloS One; Hara H, Okuda K et. al.

Dec 24th, 2021 - Recently, incidence of Mycobacterium abscessus (Mab) pulmonary disease (Mab-PD) is increasing worldwide. We aimed to identify factors associated with severity of Mycobacterium abscessus (Mab) pulmonary disease (Mab-PD). All patients diagnosed as Mab-PD based on the official ATS/IDSA statement between 2017 January 1 and 2021 July 31 were included (n = 13). We reviewed medical records, bacteriolo...

Brewing Love: Physician Spouses Grow Kombucha Business in NYC
https://www.medscape.com/viewarticle/965384

Dec 22nd, 2021 - Tucked away in the up-and-coming neighborhood of Bushwick, Brooklyn, beyond warehouses full of artist studios, tattoo shops, and used book stores, lies a little corner of serenity: BKE Kombucha. Located on a quiet street (well, quiet for Brooklyn), the kombucha brewery offers a place of respite for owners Saleena Subaiya and Lawrence Purpura. For Subaiya, an emergency medicine physician, and Pu...

Streptococcus gordonii DL1 evades polymorphonuclear leukocyte-mediated killing via resi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687581
PloS One; Urano-Tashiro Y, Saiki K et. al.

Dec 21st, 2021 - Streptococcus gordonii is an etiological bacterial agent of infective endocarditis. Although the pathogenesis mechanisms are not well understood, the interaction between streptococci and phagocytes is considered important for the development of infective endocarditis. Previous studies show that some S. gordonii strains, including DL1, survive in polymorphonuclear leukocytes (PMNs), whereas othe...

Healthcare-associated links in transmission of nontuberculous mycobacteria among people...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687591
PloS One; Gross JE, Caceres S et. al.

Dec 21st, 2021 - Healthcare-associated transmission of nontuberculous mycobacteria (NTM) among people with cystic fibrosis (pwCF) has been reported and is of increasing concern. No standardized epidemiologic investigation tool has been published for healthcare-associated NTM outbreak investigations. This report describes the design of an ongoing observational study to standardize the approach to NTM outbreak in...

Epidemiological profile of multidrug-resistant and extensively drug-resistant Mycobacte...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684270
Annals of Clinical Microbiology and Antimicrobials; Elion Assiana DO, Abdul JBPA et. al.

Dec 19th, 2021 - There is paucity of data on the prevalence and distribution of multidrug- Resistant-Tuberculosis (MDR-TB) in the Republic of Congo. Among the challenges resides the implementation of a robust TB resistance diagnostic program using molecular tools. In resource limited settings there is a need to gather data to enable prioritization of actions. The objective of this study was is to implement mole...

Equivalence of the GeneXpert System and GeneXpert Omni System for tuberculosis and rifa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682871
PloS One; Georghiou SB, Alagna R et. al.

Dec 18th, 2021 - A laboratory validation study was conducted to assess the equivalence of Xpert MTB/RIF Ultra testing on the GeneXpert System and the GeneXpert Omni System ('Omni') for tuberculosis and rifampicin resistance. High concordance of the two devices was demonstrated for well-characterized clinical samples as well as control materials, with controls tested on Omni at normal and challenging environment...

Laboratory diagnostic, epidemiological, and clinical characteristics of human leptospir...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670671
PLoS Neglected Tropical Diseases; Kakita T, Okano S et. al.

Dec 15th, 2021 - Leptospirosis is considered an endemic disease among agricultural workers in Okinawa Prefecture, which is the southernmost part of Japan and has a subtropical climate, but data on the current status and trend of this disease are scarce. We conducted a retrospective study of clinically suspected leptospirosis patients whose sample and information were sent to the Okinawa Prefectural Institute of...

Surveillance for diseases, pathogens, and toxicants of muskrat (Ondatra zibethicus) in ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659318
PloS One; Ganoe LS, Brown JD et. al.

Dec 10th, 2021 - Using diagnostic data and contemporary sampling efforts, we conducted surveillance for a diversity of pathogens, toxicants, and diseases of muskrats (Ondatra zibethicus). Between 1977 and 2019, 26 diagnostic cases were examined from Kansas and throughout the Southeast and Mid-Atlantic, USA. We identified multiple causes of mortality in muskrats, but trauma (8/26), Tyzzer's disease (5/6), and cy...

Environmental predictors of pulmonary nontuberculous mycobacteria (NTM) sputum positivi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659685
PloS One; Foote SL, Lipner EM et. al.

Dec 10th, 2021 - Nontuberculous mycobacteria (NTM) are opportunistic human pathogens that are commonly found in soil and water, and exposure to these organisms may cause pulmonary nontuberculous mycobacterial disease. Persons with cystic fibrosis (CF) are at high risk for developing pulmonary NTM infections, and studies have shown that prolonged exposure to certain environments can increase the risk of pulmonar...

A 31-Year-Old Man With Seizures, Brain Lesion, and Lung Nodules.
https://doi.org/10.1016/j.chest.2021.07.051
Chest Maskin LP, Garcia Hernandez MH et. al.

Dec 8th, 2021 - A 31-year-old man was admitted to our hospital with a recent history of generalized seizures. Three months earlier, he started with intermittent hemoptysis. CT scan showed a cavitary lung lesion in the upper segment of the right inferior lobe (RIL). Because of his job as a social worker in a high-risk population, he started treatment for Mycobacterium TB; however, the BAL culture result was neg...

Current practices of management of maternal and congenital Cytomegalovirus infection du...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641894
PloS One; Périllaud-Dubois C, Belhadi D et. al.

Dec 4th, 2021 - Congenital CMV infection is the first worldwide cause of congenital viral infection but systematic screening of pregnant women and newborns for CMV is still debated in many countries. This systematic review aims to provide the state of the art on current practices concerning management of maternal and congenital CMV infection during pregnancy, after maternal primary infection (PI) in first trim...

Hypha essential genes in Candida albicans pathogenesis of oral lichen planus: an in-vit...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638143
BMC Oral Health; He H, Wang Y et. al.

Dec 3rd, 2021 - Hypha essential genes (HEGs) of Candida Albicans have been emerging into scholar's attention, little known about their functions in oral lichen planus (OLP) with an uncovered etiology. This research aimed to observe necessary genes in biphasic C. albicans from OLP and study their relevance in pathogenesis, so as to evaluate possible roles of morphologic switching in etiology of OLP. Samples wer...

Altered cervicovaginal microbiota in premenopausal ovarian cancer patients.
https://doi.org/10.1016/j.gene.2021.146083
Gene Morikawa A, Kawabata A et. al.

Dec 3rd, 2021 - Nearly three hundred thousand female patients are diagnosed with ovarian cancer in the world annually, and this number shows an increasing trend. However, characteristic symptoms caused by ovarian cancer are so few that early diagnosis remains challenging, and an effective screening method has not yet been established. Here, we conducted a case-control study in Japan to analyze the association ...

Bacterial variation in the oral microbiota in multiple sclerosis patients.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631616
PloS One; Zangeneh Z, Abdi-Ali A et. al.

Dec 1st, 2021 - Microorganisms in oral cavity are called oral microbiota, while microbiome consists of total genome content of microorganisms in a host. Interaction between host and microorganisms is important in nervous system development and nervous diseases such as Autism, Alzheimer, Parkinson and Multiple Sclerosis (MS). Bacterial infections, as an environmental factor in MS pathogenesis play role in T hel...

Meningitis caused by Mycobacterium tuberculosis in a recent immigrant to Canada.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654888
CMAJ : Canadian Medical Association Journal = Journal De ... Komorowski AS, Lo CKL et. al.

Dec 1st, 2021 - Meningitis caused by Mycobacterium tuberculosis in a recent immigrant to Canada.|2021|Komorowski AS,Lo CKL,Irfan N,Singhal N,|drug therapy,microbiology,isolation & purification,