×
About 372,000 results

Hsa_circ_0020850 promotes the malignant behaviors of lung adenocarcinoma by regulating ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750879
World Journal of Surgical Oncology; Li X, Su S et. al.

Jan 12th, 2022 - Circular RNAs (circRNAs) are a novel type of endogenous RNAs and play vital roles in lung adenocarcinoma. However, the function and underlying mechanism of circ_0020850 in lung adenocarcinoma remain unknown. The levels of circ_0020850, microRNA-326 (miR-326), and Beclin1 (BECN1) were analyzed by real-time quantitative polymerase chain reaction and western blot analyses. The migration and invasi...

The role of vascular invasion and lymphatic invasion in predicting recurrent thoracic o...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744266
World Journal of Surgical Oncology; Ma Y, Yao X et. al.

Jan 12th, 2022 - Numerous studies have addressed lymphovascular invasion (LVI) in patients with thoracic oesophageal squamous cell carcinoma (ESCC); however, little is known about the individual roles of lymphatic invasion (LI) and vascular invasion (VI). We aimed to analyse the prognostic significance of LI and VI in patients with thoracic ESCC from a single centre. This retrospective study included 396 patien...

Data from small cell neuroendocrine carcinoma of the cervix: FIGO 2018 staging is more ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753085
The Journal of International Medical Research; Zhang Y, Ding J et. al.

Jan 7th, 2022 - To compare the prognostic value of International Federation of Gynecology and Obstetrics (FIGO) 2009 and 2018 staging systems in surgical patients with small cell neuroendocrine carcinoma of the cervix (SCNEC). We re-staged 64 surgical IB-IIA (FIGO 2009) SCNEC patients according to the FIGO 2018 system and refined stage IIIC of FIGO 2018 based on tumor local invasion. The prognostic factors wer...

A Population-Based Analysis of Diabetes-Related Care Measures, Foot Complications, and ...
https://doi.org/10.1001/jamanetworkopen.2021.42354
JAMA Network Open; de Mestral C, Gomez D et. al.

Jan 6th, 2022 - Deferred diabetic foot screening and delays in timely care of acute foot complications during the COVID-19 pandemic may have contributed to an increase in limb loss. To evaluate the association of the COVID-19 pandemic with diabetes-related care measures, foot complications, and amputation. This population-based cohort study included all adult residents of Ontario, Canada, with diabetes and com...

Preoperative Risk Factors for Fibrosarcomatous Transformation in Dermatofibrosarcoma Pr...
https://doi.org/10.21873/anticanres.15463
Anticancer Research; Mallett KE, Almubarak S et. al.

Jan 1st, 2022 - Dermat of ibrosarcoma protuberans (DFSP) is a soft-tissue sarcoma with a high risk of local recurrence, though typically never metastasizes. DFSP can transform into high-grade fibrosarcoma (DFSP-FS), which has a risk of metastasis. Currently, treatment for DFSP includes Moh's micrographic surgery (MMS); however, this is not recommended for DFSP-FS. Often, the transformation to DFSP-FS is not re...

The Benefit of Postoperative Radiotherapy and Extending Neck Dissection in pT1-2 Oral S...
https://doi.org/10.21873/anticanres.15462
Anticancer Research; Alsharif U, Steller D et. al.

Jan 1st, 2022 - We compared postoperative radiotherapy (PORT) to surgery only (SO), and supraomohyoidal neck dissection (SOHND) to modified radical neck dissection (MRND) in patients with pT1-T2 squamous cell carcinomas of the oral cavity (OSCC) and a single cervical lymph node metastasis (pN1) in terms of overall survival (OS), oral cancer specific survival (OCSS), and regional recurrence-free survival (RRFS)...

Prevalence of Diabetes and Impaired Fasting Glycemia in Patients With Oral Cancer: A Re...
https://doi.org/10.21873/anticanres.15464
Anticancer Research; Vegh A, Banyai D et. al.

Jan 1st, 2022 - Diabetes mellitus (DM) is one of the most common chronic metabolic disorders. Our research aimed to demonstrate the relationship between DM and oral cancer. We pursued a retrospective research study in Hungary between January 2019 and December 2020. We investigated 597 inpatient records and compared them to the results of our previous studies (1998-2002 and 2012-2015). The frequency of patients...

Scoring Systems of Peritoneal Dissemination for the Prediction of Operative Completenes...
https://doi.org/10.21873/anticanres.15465
Anticancer Research; Hosoya S, Ueda K et. al.

Jan 1st, 2022 - We investigated the predictive value of scoring systems of peritoneal disseminations for complete surgery (CS) at primary debulking surgery (PDS) in advanced ovarian cancer. We retrospectively enrolled eligible patients with clinical stages III or IVA selected for PDS from January 2015 to December 2019. Concern variables were predictive index value (PIV) and peritoneal cancer index (PCI) from o...

Current Status of Metastatic Cardiophrenic Lymph Nodes (CPLNs) in Patients With Ovarian...
https://doi.org/10.21873/anticanres.15452
Anticancer Research; Acs M, Piso P et. al.

Jan 1st, 2022 - One of the most common sites of extra-abdominal disease spread of advanced stage ovarian cancer is the cardiophrenic lymph node (CPLN) region. The role and impact of extra-abdominal cytoreduction is not obvious in patients with cardiophrenic lymph node metastases. We examined the relevant and currently available literature to determine the prognostic value and management of enlarged CPLNs in ov...

Efficacy and Safety of Lenvatinib for Patients With Advanced Hepatocellular Carcinoma: ...
https://doi.org/10.21873/anticanres.15471
Anticancer Research; Shimozato N, Namisaki T et. al.

Jan 1st, 2022 - We evaluated real-world efficacy and toxicity of lenvatinib in 142 patients with advanced hepatocellular carcinoma (HCC) at six tertiary referral centres. The patients with advanced HCC treated with lenvatinib were grouped into two categories based on REFLECT criteria for analysis of efficacy and safety. The primary endpoint was progression-free survival (PFS). The objective response rate (ORR)...

ypN0 in Patients With Definitive cN-positive Status After Preoperative Treatment Is a P...
https://doi.org/10.21873/anticanres.15473
Anticancer Research; Yoshida T, Nishino T et. al.

Jan 1st, 2022 - Histopathological tumor regression grade is applied not to lymph nodes but primary tumors modified by preoperative treatments. This study focused on patients whose pathological examination at the time of surgery showed no residual tumor after chemo(radio)therapy in the primary lesion (ypT0) or lymph nodes (ypN0). A total of 87 patients with clinical stage II/III thoracic esophageal cancer under...

Mac-2 Binding Protein Glycosylation Isomer as a Prognostic Marker for Hepatocellular Ca...
https://doi.org/10.21873/anticanres.15479
Anticancer Research; Harimoto N, Itoh S et. al.

Jan 1st, 2022 - Mac2-binding protein glycosylation isomer (M2BPGi) is a non-invasive marker for assessing liver fibrosis. This was a retrospective study investigating whether M2BPGi predicts recurrence of hepatocellular carcinoma (HCC) after hepatectomy in patients with HCC who achieved a sustained virological response (SVR). We retrospectively reviewed the clinicopathological factors from 60 patients who unde...

Chloride Intracellular Channel 1 Expression Is Associated With Poor Prognosis of Lung A...
https://doi.org/10.21873/anticanres.15482
Anticancer Research; Yasuda Y, Nagano T et. al.

Jan 1st, 2022 - Chloride intracellular channel 1 (CLIC1) is a member of the chloride channel protein family. The aim of this study was to clarify the role of CLIC1 in lung adenocarcinoma. The expression levels of CLIC1 in 74 patients with completely resected lung adenocarcinoma were analyzed by immunohistochemistry. Overall survival was assessed in relation to the expression level of CLIC1. Moreover, in the lu...

Predictive Factors of Late Cervical Lymph Node Metastasis Using Intraoral Sonography in...
https://doi.org/10.21873/anticanres.15484
Anticancer Research; Konishi M, Fujita M et. al.

Jan 1st, 2022 - The objective of this study was to investigate the predictive factors of late cervical lymph node metastasis in patients with tongue cancer, based on the intraoral ultrasonographic (IUS) findings of the primary tongue lesion. Patients with T1/2N0M0 primary tongue cancer (n=106) were examined using IUS between September 2014 and September 2020. The relationships between the incidence of late cer...

The Clinical Desire for Pressurized Intraperitoneal Aerosol Chemotherapy in South Korea...
https://doi.org/10.21873/anticanres.15494
Anticancer Research; Lee EJ, Park SJ et. al.

Jan 1st, 2022 - To evaluate the clinical desire for pressurized intraperitoneal aerosol chemotherapy (PIPAC) in South Korea. We performed an online survey on surgical oncologists between November and December 2019 using a questionnaire consisting of 20 questions. A total of 164 respondents answered the questionnaire. Among those specialized in ovarian cancer, pseudomyxoma peritonei, and malignant mesothelioma ...

A Case of Mesenteric Desmoid Tumor Causing Bowel Obstruction After Laparoscopic Surgery.
https://doi.org/10.21873/anticanres.15496
Anticancer Research; Arima K, Komohara Y et. al.

Jan 1st, 2022 - A desmoid tumor is a rare neoplasm that is derived from soft tissues. Although it shows benign characteristics pathologically, local recurrence can occur. We herein report the case of a patient with an intraabdominal desmoid tumor that developed 3 years after laparoscopic appendectomy for acute appendicitis. A 59-year-old male visited our emergency room with complaints of abdominal pain and ful...

Blockade of GRP78 Translocation to the Cell Surface by HDAC6 Inhibition Suppresses Prol...
https://doi.org/10.21873/anticanres.15505
Anticancer Research; Kim C, Lee S et. al.

Jan 1st, 2022 - HDAC6, a cytoplasmic localized deacetylase, is a positive regulator of cancer progression via modification of various substrates. We evaluated how the interaction between HDAC6 and glucose regulatory protein 78 (GRP78) affects the growth of cholangiocarcinoma (CCA). The anti-tumor effects of ACY-1215, an HDAC6 specific inhibitor, in CCA cell lines were analyzed by cell viability assay, western ...

A Single Nucleotide Polymorphism (SNP) in the SLC22A3 Transporter Gene Is Associated Wi...
https://doi.org/10.21873/anticanres.15497
Anticancer Research; Li J, Persaud AK et. al.

Jan 1st, 2022 - It has been reported that expression of OCT3 enhanced the sensitivity to melphalan in cells, indicative of potential roles of OCT3 in melphalan transport. Herein we investigated the association of select single nucleotide polymorphisms in SLC22A3 (gene encoding OCT3) with clinical outcomes in multiple myeloma (MM) patients with hematopoietic autologous stem cell transplants followed by high-dos...

Transoral laryngeal microsurgery for early-stage laryngeal basaloid squamous cell carci...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719125
BMJ Case Reports; Verro B, Saraniti C

Jan 1st, 2022 - A 71-year-old man presented to our otolaryngology clinic with dysphagia and dyspnoea. He had a history of smoking for 40 years. Laryngoscopy showed an exophytic, round mass on the left aryepiglottic fold that was entirely excised by transoral laser CO2 microsurgery. Histological assessment revealed a pT1 basaloid squamous cell carcinoma (BSCC) with free-margin resection. He underwent close foll...

Reirradiation Using 198Au Grain Brachytherapy for Recurrent Oral Cancer Cases Previousl...
https://doi.org/10.21873/anticanres.15485
Anticancer Research; Konishi M, Takeuchi Y et. al.

Jan 1st, 2022 - We investigated treatment outcomes and complications during reirradiation of patients with oral cancers. Six patients who received definitive radiotherapy for oral cancer as the initial treatment and brachytherapy for recurrence were included. Local control and overall survival rates, soft tissue and mandibular complications, and tooth extraction were investigated. The five-year local control a...