×
About 21,560 results

The mechanism of radiotherapy for lung adenocarcinoma in promoting protein SIRT6-mediat...
https://doi.org/10.1177/03946320221130727
International Journal of Immunopathology and Pharmacology; Wang J, Sheng Z et. al.

Sep 30th, 2022 - Lung cancer has the fastest increase in morbidity and mortality, and is one of the most threatening malignant tumors to human health and life. Both radiotherapy and targeted therapy are typical treatments after lung cancer surgery. Radiotherapy is a means of locally killing cancer lesions, and it plays an important role in the entire management of lung cancer. Gefitinib is one of the most commo...

Stereotactic body radiotherapy versus radiofrequency ablation as initial treatment of s...
https://doi.org/10.1097/MEG.0000000000002442
European Journal of Gastroenterology & Hepatology; Shin HS, Hwan Lee S et. al.

Sep 29th, 2022 - Stereotactic body radiotherapy (SBRT) may be an alternative treatment for patients with small (≤3 cm) hepatocellular carcinomas (HCCs) who were not indicated for resection or local ablation therapy. This study compared the therapeutic effects of radiofrequency ablation (RFA) and SBRT in patients with small (≤3 cm) HCCs. Data of HCC patients who underwent SBRT or RFA as an initial treatment at f...

Stereotactic body radiotherapy for recurrent and oligometastatic soft tissue sarcoma.
https://doi.org/10.1186/s12957-022-02781-1
World Journal of Surgical Oncology; Feng XY, Li J et. al.

Sep 29th, 2022 - Soft tissue sarcoma (STS) is a malignant tumor of highly heterogeneous mesenchymal origin. STS has a biological pattern and clinical transformation with localized invasive growth and is susceptible to hematogenous metastasis. Local therapeutic strategies may treat recurrent and oligometastatic STS, including surgery and radiation therapy. This study aimed to evaluate the safety and efficacy of ...

Effect of thoracic radiotherapy dose on the prognosis of advanced lung adenocarcinoma h...
https://doi.org/10.1186/s12885-022-10095-4
BMC Cancer; Qin H, Ke J et. al.

Sep 25th, 2022 - The aim of this study was to investigate the effects of different thoracic radiotherapy doses on OS and incidence of radiation pneumonia which may provide some basis for optimizing the comprehensive treatment scheme of these patients with advanced EGFR mutant lung adenocarcinoma. Data from 111 patients with EGFR-mutant lung adenocarcinoma who received thoracic radiotherapy were included in this...

Hysteroscopic Resection Followed by Adjuvant Radiotherapy: Report of a New Therapeutic ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9517014
International Journal of Environmental Research and Publi... Stabile G, Sancin L et. al.

Sep 24th, 2022 - The female genital tract can be involved as a secondary manifestation of disseminated lymphomas or leukemia but can rarely be the primary site of so-called extranodal lymphomas. Primary lymphomas of the female genital tract can affect the uterine corpus, uterine cervix, vulva, vagina or adnexa. Only about 0.008% of all cervical tumors are primary malignant lymphomas. The presenting symptoms are...

Changes in Apparent Diffusion Coefficient (ADC) in Serial Weekly MRI during Radiotherap...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498049
Current Oncology (Toronto, Ont.); Ng SP, Cardenas CE et. al.

Sep 23rd, 2022 - Background: The PREDICT-HN study aimed to systematically assess the kinetics of imaging MR biomarkers during head and neck radiotherapy. Methods: Patients with intact squamous cell carcinoma of the head and neck were enrolled. Pre-, during, and post-treatment MRI were obtained. Serial GTV and ADC measurements were recorded. The correlation between each feature and the GTV was calculated using S...

Relationship between Salivary Amylase and Xerostomia in Intensity-Modulated Radiation T...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497840
Current Oncology (Toronto, Ont.); De Felice F, Scarabelli MG et. al.

Sep 23rd, 2022 - A single-institution prospective pilot study was conducted to the assess correlation between salivary amylase and xerostomia in patients with head and neck squamous cell carcinoma (HNSCC) treated with intensity-modulated radiotherapy (IMRT). Serum saliva amylase, clinician-reported xerostomia (using Common Terminology Criteria for Adverse Events), and patient-reported xerostomia (using 8-item s...

Combined nivolumab and ipilimumab with or without stereotactic body radiation therapy f...
https://doi.org/10.1016/S0140-6736(22)01659-2
Lancet (London, England); Kim S, Wuthrick E et. al.

Sep 16th, 2022 - Merkel cell carcinoma is among the most aggressive and lethal of primary skin cancers, with a high rate of distant metastasis. Anti-programmed death receptor 1 (anti-PD-1) and programmed death ligand 1 (PD-L1) monotherapy is currently standard of care for unresectable, recurrent, or metastatic Merkel cell carcinoma. We assessed treatment with combined nivolumab plus ipilimumab, with or without ...

The first reported case of a patient with pancreatic cancer treated with cone beam comp...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472353
Radiation Oncology (London, England); Kim M, Schiff JP et. al.

Sep 14th, 2022 - Online adaptive stereotactic radiotherapy allows for improved target and organ at risk (OAR) delineation and inter-fraction motion management via daily adaptive planning. The use of adaptive SBRT for the treatment of pancreatic cancer (performed until now using only MRI or CT on rails-guided adaptive radiotherapy), has yielded promising outcomes. Herein we describe the first reported case of co...

Dosimetric comparison between VMAT plans using the fast-rotating O-ring linac with dual...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465858
Radiation Oncology (London, England); Ju SG, Ahn YC et. al.

Sep 13th, 2022 - To compare the dosimetric profiles of volumetric modulated arc therapy (VMAT) plans using the fast-rotating O-ring linac (the Halcyon system) based on a dual-layer stacked multi-leaf collimator and helical tomotherapy (HT) for nasopharyngeal cancer (NPCa). For 30 NPCa patients, three sets of RT plans were generated, under the same policy of contouring and dose constraints: HT plan; Halcyon VMAT...

Gut microbiota modulate radiotherapy-associated antitumor immune responses against hepa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467592
Gut Microbes; Li Z, Zhang Y et. al.

Sep 13th, 2022 - Studies of the gut-liver axis have enhanced our understanding of the pathophysiology of various liver diseases and the mechanisms underlying the regulation of the effectiveness of therapies. Radiotherapy (RT) is an important therapeutic option for patients with unresectable hepatocellular carcinoma (HCC). However, the role of the microbiome in regulating the response to RT remains unclear. The ...

Comparison of Prospectively Generated Glioma Treatment Plans Clinically Delivered on Ma...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459463
Technology in Cancer Research & Treatment; Wang MH, Kim A et. al.

Sep 9th, 2022 - Introduction: Magnetic resonance imaging-linear accelerator radiotherapy is an innovative technology that requires special consideration for secondary electron interactions within the magnetic field, which can alter dose deposition at air-tissue interfaces. As part of ongoing quality assurance and quality improvement of new radiotherapy technologies, the purpose of this study was to evaluate sk...

Prognostic Relevance of Change in Body Mass Index in Patients With Nasopharyngeal Carci...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9468699
Cancer Control : Journal of the Moffitt Cancer Center; Lin X, Wang B et. al.

Sep 9th, 2022 - To assess the effect of pretreatment body mass index (BMI) and the extent of change in BMI (ΔBMI) during the treatment course on the treatment outcomes in patients with nasopharyngeal carcinoma (NPC) receiving volumetric modulated arc therapy (VMAT). Data pertaining to 498 consecutive NPC patients with stage I-IVA disease who received VMAT between January 2010 and November 2011 at a single cent...

UBE2C mediated radiotherapy resistance of head and neck squamous cell carcinoma by regu...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9512496
Aging Zhou Y, Zhang J et. al.

Sep 8th, 2022 - Radiotherapy resistance is the main obstacle in the effective treatment of advanced head and neck squamous cell carcinoma (HNSCC). Increasing scientific opinions present that ubiquitin-conjugating enzyme E2C (UBE2C) might be a target gene acting as an oncogene. TCGA database was used to analyze the expression of UBE2C in HNSCC patients, and the relationship between UBE2C expression and prognosi...

Pre- and postdiagnosis growth failure, adult short stature, and untreated growth hormon...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447887
PloS One; Anttonen J, Remes T et. al.

Sep 7th, 2022 - Growth failure is common in radiotherapy-treated long-term survivors of pediatric brain tumors, but studies on longitudinal growth in this patient group are lacking. Here, the aim was to assess the changes in growth patterns before and after brain tumor diagnosis, the adult height, and the risk factors for compromised growth. The incidence and treatment practices of growth hormone deficiency we...

MicroRNA-613 Enhances Nasopharyngeal Carcinoma Cell Radiosensitivity via the DNA Methyl...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439912
Disease Markers; Deng L, Yin Q et. al.

Sep 6th, 2022 - Nasopharyngeal carcinoma (NPC) is a common malignancy of the nasopharynx, and radioresistant represents the main obstacle in NPC treatment. Malignant transformation of normal cells is driven by genetic and epigenetic changes, which are primarily manifested as changes in miRNA levels and DNA methylation status. microRNA (miR)-613 plays an inhibitory role in several types of cancer. Herein, the c...

Association between postoperative radiotherapy for young-onset head and neck cancer and...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446763
Journal of Translational Medicine; Zhu X, Zhou J et. al.

Sep 6th, 2022 - Second primary malignancy (SPM) represents the leading long-term cause of death among patients with index head and neck squamous cell carcinoma (HNSCC). We aimed to quantify the association between postoperative radiotherapy (PORT) and the risk of SPM development for index HNSCC among adolescent and young patients, who are particularly vulnerable to radiation-associated impacts due to their inc...

Radiated glioblastoma cell-derived exosomal circ_0012381 induce M2 polarization of micr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441045
Journal of Translational Medicine; Zhang C, Zhou Y et. al.

Sep 5th, 2022 - Radiotherapy is the primary therapeutic option for glioblastoma. Some studies proved that radiotherapy increased the release of exosomes from cells. The mechanism by which these exosomes modify the phenotype of microglia in the tumor microenvironment to further determine the fate of irradiated glioblastoma cells remains to be elucidated. We erected the co-culture system of glioblastoma cells an...

Leaving Lytic Lesions-Is There New Role for Radiation in Multiple Myeloma in the CAR T ...
https://doi.org/10.1016/j.prro.2022.05.002
Practical Radiation Oncology; Ababneh HS, Raje NS et. al.

Sep 5th, 2022 - Leaving Lytic Lesions-Is There New Role for Radiation in Multiple Myeloma in the CAR T Era?|2022|Ababneh HS,Raje NS,Yee AJ,Patel CG,|radiotherapy,

Variation in Routine Use of a 60 to 63 Gy Intermediate Dose Clinical Target Volume With...
https://doi.org/10.1016/j.prro.2022.03.010
Practical Radiation Oncology; Freedman L, Galloway T et. al.

Sep 5th, 2022 - Variation in Routine Use of a 60 to 63 Gy Intermediate Dose Clinical Target Volume With Primary Radiation therapy for Mucosal Squamous Cell Carcinoma of the Head and Neck.|2022|Freedman L,Galloway T,Hu K,Mierzwa M,|pathology,radiotherapy,radiotherapy,radiotherapy,