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About 20,550 results

Evaluation of 5 Fraction Stereotactic Body Radiation Therapy (SBRT) for Osseous Renal C...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699181
American Journal of Clinical Oncology; Dove APH, Wells A et. al.

Nov 23rd, 2022 - The best fractionation for stereotactic body radiotherapy (SBRT) in renal cell carcinoma (RCC) metastases has not been well defined. In addition, the literature on outcomes using 5-fraction SBRT in the setting of osseous metastases has not been well reported. Thirty-nine patients with 69 RCC osseous metastases were treated using 5-fraction SBRT at a single institution using 2 dose-fractionation...

Comparison of clinicopathological features and prognostic significance between synchron...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675276
BMC Cancer; Yang Y, Tang P et. al.

Nov 20th, 2022 - Synchronous multiple primary esophageal squamous cell carcinoma (S-MPESCC) refers to more than one primary esophageal carcinoma detected in a solitary patient at the time of initial presentation. The purpose of this study was to evaluate the clinicopathological features, appropriate surgical approaches and long-term survival in patients with S-MPESCC by comparing with those with solitary esopha...

Short-term prognosis for hepatocellular carcinoma patients with lung metastasis: A retr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666127
Medicine Chen S, Li X et. al.

Nov 19th, 2022 - Our study aimed to develop a prediction model to predict the short-term mortality of hepatocellular carcinoma (HCC) patients with lung metastasis. The retrospective data of HCC patients with lung metastasis was from the Surveillance, Epidemiology, and End Results registration database between 2010 and 2015. 1905 patients were randomly divided into training set (n = 1333) and validation set (n =...

Development and Validation of Nomograms to Assess Risk Factors and Overall Survival Pre...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626197
International Journal of Clinical Practice; Liu Z, Li G et. al.

Nov 17th, 2022 - To establish two nomograms to quantify the diagnostic factors of lung metastasis (LM) and their role in assessing prognosis in young patients with LM osteosarcoma. A total of 618 osteosarcoma young patients from 2010 to 2015 were included from the Surveillance, Epidemiology, and End Results (SEER) database. Another 131 patients with osteosarcoma from local hospitals were also collected as an ex...

Metastatic angiosarcoma in a bone marrow biopsy.
https://doi.org/10.1182/blood.2022018036
Blood Germans SK, Weinberg OK

Nov 4th, 2022 - Metastatic angiosarcoma in a bone marrow biopsy.|2022|Germans SK,Weinberg OK,|secondary,pathology,pathology,pathology,

PIM3 kinase promotes tumor metastasis in hepatoblastoma by upregulating cell surface ex...
https://doi.org/10.1007/s10585-022-10186-3
Clinical & Experimental Metastasis; Marayati R, Julson J et. al.

Nov 1st, 2022 - Patients presenting with metastatic hepatoblastoma have limited treatment options and survival rates as low as 25%. We previously demonstrated that Proviral Integration site in Maloney murine leukemia virus 3 (PIM3) kinase promotes tumorigenesis and cancer cell stemness in hepatoblastoma. In this study, we assessed the role of PIM3 kinase in promoting hepatoblastoma metastasis. We utilized a ta...

A curious case of metastatic parotid adenoid cystic carcinoma to kidney.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621166
BMJ Case Reports; Ho NX, O'Meara S et. al.

Oct 29th, 2022 - A woman in her 60s presented with a 2-week history of non-specific left-sided abdominal pain. She previously underwent a total parotidectomy and adjuvant radiotherapy for left parotid adenoid cystic carcinoma 13 years prior, with a local recurrence 4 years after. Investigations revealed a large left-sided renal mass with appearances of renal carcinoma and no signs of metastatic disease. Patholo...

Time optimization of gadobutrol-enhanced brain MRI for metastases and primary tumors us...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575215
BMC Medical Imaging; Seo J, Lim C et. al.

Oct 18th, 2022 - Recent advances in rapid imaging techniques necessitate the reconsideration of the optimal imaging delay time for contrast-enhanced T1-weighted imaging. The aim of our study was to determine the optimal contrast-enhanced T1-weighted imaging delay time from the obtained time-signal intensity curve (TIC) using gadobutrol in patients with brain metastases, primary brain tumors, and meningiomas. Th...

Real-world outcomes with ipilimumab and nivolumab in advanced melanoma: a multicentre r...
https://doi.org/10.1016/j.ejca.2022.09.004
European Journal of Cancer (Oxford, England : 1990); Serra-Bellver P, Versluis JM et. al.

Oct 11th, 2022 - To assess efficacy and toxicity of combination immunotherapy with ipilimumab plus nivolumab in routine practice in a retrospective multicentre cohort of patients with advanced melanoma. This retrospective analysis included patients with advanced melanoma treated with ipilimumab and nivolumab between October 2015 and January 2020 at six centres in Australia, Europe and the United States of Ameri...

Clinical characteristics and outcomes in those with primary extrahepatic malignancy and...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446745
BMC Gastroenterology; Alshuwaykh O, Cheung A et. al.

Sep 6th, 2022 - Malignancy-related ascites accounts for approximately 10% of causes of ascites. Our AIM was to characterize the ascites fluid and correlate clinical outcomes in those with extrahepatic malignancy and ascites. 241 subjects with extrahepatic solid tumors and ascites were reviewed from 1/1/2000 to 12/31/2019, 119 without liver metastasis and 122 with liver metastasis. Ascites fluid consistent with...

Massive cholangiocarcinoma metastasis compressing the heart in silence.
https://doi.org/10.1093/ehjci/jeac173
European Heart Journal. Cardiovascular Imaging; Pereira T, Cardoso AF et. al.

Aug 31st, 2022 - Massive cholangiocarcinoma metastasis compressing the heart in silence.|2022|Pereira T,Cardoso AF,Cordeiro F,Azevedo O,Lourenço A,|diagnostic imaging,pathology,secondary,diagnostic imaging,pathology,pathology,

Gene expression profile of human colorectal cancer identified NKTR as a biomarker for l...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467399
Aging Bai R, Shi Z et. al.

Aug 26th, 2022 - Liver metastasis is one of the prognostic factors of colorectal cancer (CRC). The aim of this study is to identify biomarkers that facilitate easier detection of liver metastasis. Significance Analysis of Microarrays (SAM) and Array Data Analyzer (ADA) were applied used for the analysis of differentially differently expressed mRNAs. mRNA expression was verified by quantitative real-timer revers...

Intrathecal therapy for the management of leptomeningeal metastatic disease: a scoping ...
https://doi.org/10.1007/s11060-022-04118-0
Journal of Neuro-oncology; Palmisciano P, Watanabe G et. al.

Aug 24th, 2022 - Leptomeningeal metastatic disease (LMD) from advanced malignancies has poor prognoses and limited treatments. Intrathecal therapy (ITT) protocols are available, showing variable outcomes. We reviewed the therapeutic and toxicity profiles of ITT in LMD. PubMed, EMBASE, Web-of-Science, and Scopus were searched following the PRISMA-ScR guidelines to include studies reporting ITT for LMD. gov and C...

RAB27A and RAB27B Expression May Predict Lymph Node Metastasis and Survival in Patients...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353728
Cancer Genomics & Proteomics; An HJ, Lee JS et. al.

Aug 20th, 2022 - RAB27A and RAB27B are involved in exosome secretion. To date, there have been many attempts to elucidate the roles of RAB27A and RAB27B in the prognosis of various cancer types. The association of RAB27A and RAB27B expression with the clinical and pathological features was evaluated in patients with stomach cancer. A total of 360 patients who had undergone surgery for stomach cancer between Jan...

Feasibility and preliminary efficacy of tantalum components in the management of acetab...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382777
European Journal of Medical Research; Zan P, Ma X et. al.

Aug 18th, 2022 - The aim of the study was to investigate the feasibility and preliminary efficacy of tantalum components utility in the reconstruction of acetabular defects following periacetabular oncologic resection of primary malignancies. We prospectively collected a consecutive of 15 cases that were treated with tantalum components for acetabular reconstruction after periacetabular oncologic resection from...

Prognostic Factors After Pancreatectomy for Pancreatic Cancer Initially Metastatic to t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9383677
Annals of Surgical Oncology; Frigerio I, Malleo G et. al.

Aug 18th, 2022 - Resection of initially oligometastatic pancreatic ductal adenocarcinoma (PDAC) following response to first-line chemotherapy is controversial. We herein updated a previous case series to investigate the oncologic outcomes and preoperative factors that could drive the decision-making process. This retrospective analysis was limited to patients with liver-only synchronous metastases who experienc...

Long-Term Outcomes for Patients with Multiple Endocrine Neoplasia Type 1 and Duodenopan...
https://doi.org/10.1245/s10434-022-12350-1
Annals of Surgical Oncology; Liu JB, Cai J et. al.

Aug 14th, 2022 - Liver metastasis from duodenopancreatic neuroendocrine neoplasms (DP-NENs) is a major cause of mortality in multiple endocrine neoplasia type 1 (MEN1) patients, yet much of their natural history is unknown. This longitudinal, retrospective cohort study analyzed all MEN1 patients with imageable functional (F) and nonfunctional (NF) DP-NENs (1990-2021) for liver metastasis-free survival (LMFS) an...

The role of hepatic and pancreatic metastatectomy in the management of metastatic renal...
https://doi.org/10.1016/j.suronc.2022.101819
Surgical Oncology; Rodger FE, Brennan PT et. al.

Aug 9th, 2022 - Surgical resection is feasible in a small proportion of patients with oligometastatic renal cell carcinoma (mRCC) involving the liver or pancreas. The aim of this study was to evaluate the effect of liver and pancreatic resection or ablation for mRCC on survival and to identify factors associated with improved outcomes. A systematic search of the Medline and EMBASE databases was performed to id...

How to confront the high prevalence of pulmonary micro nodules (PMNs) in osteosarcoma p...
https://doi.org/10.1007/s00264-022-05534-7
International Orthopaedics; Cai Z, Xu J et. al.

Aug 9th, 2022 - Pulmonary metastasis was a negative factor of osteosarcoma prognosis. However, there is no universal criteria to confirm pulmonary metastasis at pulmonary micro nodule (PMN, Dmax ≤ 5 mm) stage other than pathology. We aimed to identify prevalence of PMNs, determine prognosis of osteosarcoma with PMNs, and analyze risk factors related to PMN progression. We retrospectively reviewed 425 consecuti...

A 24-Year-Old Man Presenting with Lung Metastases from a Primary Retroperitoneal Extrag...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361777
The American Journal of Case Reports; Koilpillai S, Sun TY et. al.

Aug 6th, 2022 - BACKGROUND Primary retroperitoneal choriocarcinoma is a rare form of extragonadal germ cell tumor that is highly aggressive and responds poorly to chemoradiation. Extragonadal choriocarcinomas are notoriously challenging to diagnose, and have often progressed to advanced disease by the time of diagnosis. The survival rate for extragonadal choriocarcinoma is approximately 30%, which is much lowe...