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About 150,480 results

Psoriatic Arthritis Diagnosis and Management in the Era of Telehealth.
https://doi.org/10.12788/cutis.0313
Cutis Han G

Oct 19th, 2021 - Psoriatic Arthritis Diagnosis and Management in the Era of Telehealth.|2021|Han G,|diagnosis,therapy,

Vitiligo: 30 years to put together the puzzle pieces and to give rise to a new era of t...
https://doi.org/10.1111/jdv.17652
Journal of the European Academy of Dermatology and Venere... Passeron T

Oct 15th, 2021 - Vitiligo: 30 years to put together the puzzle pieces and to give rise to a new era of therapeutic options.|2021|Passeron T,|therapy,

Neuroimmune multi-hit perspective of coronaviral infection.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512650
Journal of Neuroinflammation; Hayley S, Sun H

Oct 15th, 2021 - It is well accepted that environmental stressors experienced over a one's life, from microbial infections to chemical toxicants to even psychological stressors, ultimately shape central nervous system (CNS) functioning but can also contribute to its eventual breakdown. The severity, timing and type of such environmental "hits", woven together with genetic factors, likely determine what CNS outc...

COVID-19 in pediatric cancer patients is associated with treatment interruptions but no...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503711
Journal of Hematology & Oncology; Węcławek-Tompol J, Zakrzewska Z et. al.

Oct 13th, 2021 - Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently constitutes the leading and overwhelming health issue worldwide. In comparison with adults, children present milder symptoms, with most having an asymptomatic course. We hypothesized that COVID-19 infection has a negative impact on the continuation of chemotherapy and increases n...

Intraabdominal and ganglionic desmoplastic small round cell tumor: a case series.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8507229
Journal of Medical Case Reports; Slim S, Zemni I et. al.

Oct 13th, 2021 - Desmoplastic small round cell tumor is a rare malignancy with poor prognosis, affecting young male patients. It frequently presents as a large abdominal mass with widespread peritoneal involvement at diagnosis. In late stages, metastases may be present. We retrospectively reviewed patient characteristics, presenting symptoms, tumor pathology, treatment, and outcome of four patients with desmopl...

Reye Syndrome with Severe Hyperammonemia and a Good Neurological Outcome.
https://doi.org/10.12659/AJCR.932864
The American Journal of Case Reports; Pribožič L, Žerjav Tanšek M et. al.

Oct 12th, 2021 - BACKGROUND Reye syndrome (RS) is a rare life-threatening condition combining acute noninflammatory encephalopathy and acute liver failure with an absence of defined etiology. We present a case of fulminant RS that had a good neurological outcome. CASE REPORT A 4-year-old previously healthy boy had no history of acetylsalicylic acid (ASA) use, nor had he been diagnosed with any inborn errors of ...

Pancreatic cancer in 2021: What you need to know to win.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475010
World Journal of Gastroenterology; Tonini V, Zanni M

Oct 12th, 2021 - Pancreatic cancer is one of the solid tumors with the worst prognosis. Five-year survival rate is less than 10%. Surgical resection is the only potentially curative treatment, but the tumor is often diagnosed at an advanced stage of the disease and surgery could be performed in a very limited number of patients. Moreover, surgery is still associated with high post-operative morbidity, while oth...

Gastrinoma and Zollinger Ellison syndrome: A roadmap for the management between new and...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475006
World Journal of Gastroenterology; Rossi RE, Elvevi A et. al.

Oct 12th, 2021 - Zollinger-Ellison syndrome (ZES) associated with pancreatic or duodenal gastrinoma is characterized by gastric acid hypersecretion, which typically leads to gastroesophageal reflux disease, recurrent peptic ulcers, and chronic diarrhea. As symptoms of ZES are nonspecific and overlap with other gastrointestinal disorders, the diagnosis is often delayed with an average time between the onset of s...

Primary gastric non-Hodgkin lymphomas: Recent advances regarding disease pathogenesis a...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475005
World Journal of Gastroenterology; Diamantidis MD, Papaioannou M et. al.

Oct 12th, 2021 - Primary gastric lymphomas (PGLs) are distinct lymphoproliferative neoplasms described as heterogeneous entities clinically and molecularly. Their main histological types are diffuse large B-cell lymphoma (DLBCL) or mucosa-associated lymphoma tissue. PGL has been one of the main fields of clinical research of our group in recent years. Although gastric DLBCLs are frequent, sufficient data to gui...

Impact of radiogenomics in esophageal cancer on clinical outcomes: A pilot study.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476334
World Journal of Gastroenterology; Brancato V, Garbino N et. al.

Oct 12th, 2021 - Esophageal cancer (ESCA) is the sixth most common malignancy in the world, and its incidence is rapidly increasing. Recently, several microRNAs (miRNAs) and messenger RNA (mRNA) targets were evaluated as potential biomarkers and regulators of epigenetic mechanisms involved in early diagnosis. In addition, computed tomography (CT) radiomic studies on ESCA improved the early stage identification ...

Clinicopathological characteristics and longterm survival of patients with synchronous ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476333
World Journal of Gastroenterology; Wu H, Li C et. al.

Oct 12th, 2021 - Multiple gastrointestinal stromal tumors (MGISTs) are specific and rare. Little is known about the impact of MGISTs on the survival of patients with gastrointestinal stromal tumors (GIST). The diagnosis, treatment and follow-up strategies of MGISTs is not specifically described in guidelines. To compare the clinicopathological characteristics and prognosis of MGISTs and solitary GISTs (SGISTs)....

Preliminary analysis of the benefits of different irradiation types on patients with po...
https://doi.org/10.21037/apm-21-2080
Annals of Palliative Medicine; Gao HM, Shen WB et. al.

Oct 12th, 2021 - To explore the benefits of different types of irradiation on patients with postoperative locoregional recurrence (LRR) of thoracic esophageal squamous cell carcinoma (ESCC). We analyzed the medical records of 344 patients with recurrent esophageal cancer (EC) at the Fourth Hospital of Hebei Medical University. All patients met an inclusion criteria that included having postoperative LRR (withou...

Combining clinical examination with exome sequencing for the diagnosis and treatment of...
https://doi.org/10.21037/apm-21-2305
Annals of Palliative Medicine; Duan Y, Li P et. al.

Oct 12th, 2021 - Marfan syndrome (MFS) is a rare autosomal dominant connective tissue disorder. Diagnosing MFS can be challenging as the disease's severity and clinical manifestations differ between pathogenic variants, and because a lack of published information currently exists on phenotype-genotype correlations. This report aims to underline the clinical manifestations associated with fibrillin-1 (FBN1) gene...

A qualitative study on the implementation of a holistic care package for control and ma...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501530
BMC Health Services Research; Ali O, Kinfe M et. al.

Oct 10th, 2021 - Neglected Tropical Diseases (NTDs) such as podoconiosis, lymphatic filariasis (LF) and leprosy mainly affect communities in low resource settings. These diseases are associated with physical disability due to lymphoedema as well as poor mental health and psychosocial outcomes. Integration of care across these NTDs at primary health care level, which includes mental health and psychosocial care ...

Osteosarcoma: An Evolving Understanding of a Complex Disease.
https://doi.org/10.5435/JAAOS-D-20-00838
The Journal of the American Academy of Orthopaedic Surgeons; Alexander JH, Binitie OT et. al.

Oct 9th, 2021 - Osteosarcoma is the most common primary bone sarcoma and affects both children and adults. The cornerstone of treatment for patients with localized and oligometastatic disease remains neoadjuvant chemotherapy, surgical resection of all sites of disease, followed by adjuvant chemotherapy. This approach is associated with up to an 80% 5-year survival. However, survival of patients with metastatic...

Rectal mixed adenoneuroendocrine carcinoma: Case report.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500653
Medicine Silva DJ, Dos Santos J et. al.

Oct 9th, 2021 - Colorectal mixed neuroendocrine-nonneuroendocrine neoplasms constitute a rare group of gastrointestinal tumors composed by both neuroendocrine and nonneuroendocrine components. Nondiagnostic macroscopic features, specific histological features, and poor awareness of the disease are responsible for the underestimated incidence and conflicting data available. Due to lack of randomized clinical tr...

Clinical characteristics and outcomes of hospitalized patients with SARS-CoV-2 infectio...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500444
PloS One; Cordova E, Mykietiuk A et. al.

Oct 9th, 2021 - Clinical features and outcomes of SARS-CoV-2 infections diverge in different countries. The aim of this study was to describe clinical characteristics and outcomes in a cohort of patients hospitalized with SARS-CoV-2 in Argentina. Multicenter prospective cohort study of ≥18 years-old patients with confirmed SARS-CoV-2 infection consecutively admitted to 19 hospitals in Argentina. Multivariable ...

Androgen deprivation therapy and excess mortality in men with prostate cancer during th...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496782
PloS One; Gedeborg R, Styrke J et. al.

Oct 8th, 2021 - Men have a higher risk of death from COVID-19 than women and androgens facilitate entrance of the SARS-CoV-2 virus into respiratory epithelial cells. Thus, androgen deprivation therapy may reduce infection rates and improve outcomes for COVID-19. In the spring of 2020, Sweden was highly affected by COVID-19. The aim was to estimate the impact of androgen deprivation therapy on mortality from CO...

Reduced turnaround times through multi-sectoral community collaboration during the firs...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496830
PloS One; Christofferson RC, O'Neal HR et. al.

Oct 8th, 2021 - In March 2020, an influx of admissions in COVID-19 positive patients threatened to overwhelm healthcare facilities in East Baton Rouge Parish, Louisiana. Exacerbating this problem was an overall shortage of diagnostic testing capability at that time, resulting in a delay in time-to-result return. An improvement in diagnostic testing availability and timeliness was necessary to improve the alloc...

The Efficacy of the Half Somersault Maneuver in Comparison to the Epley Maneuver in Pat...
https://doi.org/10.5152/iao.2021.9072
The Journal of International Advanced Otology; Khaftari MD, Ahadi M et. al.

Oct 8th, 2021 - Benign Paroxysmal Positional Vertigo (BPPV) as the most common vestibular disorder can affect the quality of life. This study aimed to compare the effectiveness of the half somersault maneuver (HSM) as a treatment to that of the Epley maneuver (EM) as a clinical-based treatment in subjects with PC-BPPV. In this randomized study, 43 participants with unilateral posterior canal BPPV were recruite...