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About 15,795 results

Neuroimmune multi-hit perspective of coronaviral infection.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8512650
Journal of Neuroinflammation; Hayley S, Sun H

Oct 15th, 2021 - It is well accepted that environmental stressors experienced over a one's life, from microbial infections to chemical toxicants to even psychological stressors, ultimately shape central nervous system (CNS) functioning but can also contribute to its eventual breakdown. The severity, timing and type of such environmental "hits", woven together with genetic factors, likely determine what CNS outc...

The "collateral damage" of the war on COVID-19: impact of the pandemic on the care of e...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476977
Medical Oncology (Northwood, London, England); Goenka L, Anandaradje A et. al.

Sep 29th, 2021 - The covid-19 pandemic has impacted the management of non-covid-19 illnesses. Epithelial ovarian cancer (EOC) requires long-duration multidisciplinary treatment. Teleconsultation and shared care are suggested solutions to mitigate the consequences of the pandemic. However, these may be challenging to implement among patients who come from the lower economic strata. We report the disastrous impac...

Effect of the COVID-19 Pandemic on Delayed Skin Cancer Services.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8162820
Dermatologic Clinics; Rashid S, Tsao H

Sep 25th, 2021 - The COVID-19 pandemic has presented a unique set of challenges to cancer care centers around the world. Diagnostic and treatment delays associated with lockdown periods may be expected to increase the total number of avoidable skin cancer deaths. During this unprecedented time, dermatologists have been pressed to balance early surgical interventions for skin cancer with the risk of viral transm...

Bedside estimates of dead space using end-tidal CO2 are independently associated with m...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442447
Critical Care (London, England); Lecompte-Osorio P, Pearson SD et. al.

Sep 17th, 2021 - In acute respiratory distress syndrome (ARDS), dead space fraction has been independently associated with mortality. We hypothesized that early measurement of the difference between arterial and end-tidal CO2 (arterial-ET difference), a surrogate for dead space fraction, would predict mortality in mechanically ventilated patients with ARDS. We performed two separate exploratory analyses. We fir...

Neglected Parasitic Infections: What Family Physicians Need to Know-A CDC Update.
https://www.ncbi.nlm.nih.gov/pubmed/34523888
American Family Physician; Cantey PT, Montgomery SP et. al.

Sep 16th, 2021 - Chagas disease, cysticercosis, and toxoplasmosis affect millions of people in the United States and are considered neglected parasitic diseases. Few resources are devoted to their surveillance, prevention, and treatment. Chagas disease, transmitted by kissing bugs, primarily affects people who have lived in Mexico, Central America, and South America, and it can cause heart disease and death if ...

Clinical recommendations for in-hospital airway management during aerosol-transmitting ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723398
Best Practice & Research. Clinical Anaesthesiology; Fuchs A, Lanzi D et. al.

Sep 14th, 2021 - The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can lead to severe pneumonia and multiorgan failure. While most of the infected patients develop no or only mild symptoms, some need respiratory support or even invasive ventilation. The exact route of transmission is currently under investigation. While droplet exposure and...

COVID-19-associated acute respiratory distress syndrome (CARDS): Current knowledge on p...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831801
Best Practice & Research. Clinical Anaesthesiology; Pfortmueller CA, Spinetti T et. al.

Sep 14th, 2021 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces coronavirus-19 disease (COVID-19) and is a major health concern. Following two SARS-CoV-2 pandemic "waves," intensive care unit (ICU) specialists are treating a large number of COVID19-associated acute respiratory distress syndrome (ARDS) patients. From a pathophysiological perspective, prominent mechanisms of COVID19-associat...

Adaptation and restructuring of an academic anesthesiology department during the COVID-...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728432
Best Practice & Research. Clinical Anaesthesiology; Shaparin N, Mann GE et. al.

Sep 14th, 2021 - The novel SARS-CoV-2 pandemic starting in 2019 profoundly changed the world, and thousands of residents of New York City were affected, leading to one of the most acute surges in regional hospital capacity. As the largest academic medical center in the Bronx, Montefiore Medical Center was immediately impacted, and the entire hospital was mobilized to address the needs of its community. In this ...

Framework for creating an incident command center during crises.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428470
Best Practice & Research. Clinical Anaesthesiology; Kaye AD, Cornett EM et. al.

Sep 14th, 2021 - The Hospital Incident Command System (HICS) is an incident management system specific to hospitals based on the principles of Incident Command System (ICS), and it includes prevention, protection, mitigation, response, and recovery. It plays a crucial role in effective and timely response during the periods of disasters, mass casualties, and public health emergencies. In recent times, hospitals...

Machine-learning-based COVID-19 mortality prediction model and identification of patien...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424411
Critical Care (London, England); Banoei MM, Dinparastisaleh R et. al.

Sep 10th, 2021 - The coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-Cov2 virus has become the greatest health and controversial issue for worldwide nations. It is associated with different clinical manifestations and a high mortality rate. Predicting mortality and identifying outcome predictors are crucial for COVID patients who are critically ill. Multivariate and machine learning methods may ...

Trends in COVID-19 Cases, Emergency Department Visits, and Hospital Admissions Among Ch...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437056
MMWR. Morbidity and Mortality Weekly Report; Siegel DA, Reses HE et. al.

Sep 10th, 2021 - Although COVID-19 generally results in milder disease in children and adolescents than in adults, severe illness from COVID-19 can occur in children and adolescents and might require hospitalization and intensive care unit (ICU) support (1-3). It is not known whether the B.1.617.2 (Delta) variant,* which has been the predominant variant of SARS-CoV-2 (the virus that causes COVID-19) in the Unit...

Hospitalizations Associated with COVID-19 Among Children and Adolescents - COVID-NET, 1...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437052
MMWR. Morbidity and Mortality Weekly Report; Delahoy MJ, Ujamaa D et. al.

Sep 10th, 2021 - Although COVID-19-associated hospitalizations and deaths have occurred more frequently in adults,† COVID-19 can also lead to severe outcomes in children and adolescents (1,2). Schools are opening for in-person learning, and many prekindergarten children are returning to early care and education programs during a time when the number of COVID-19 cases caused by the highly transmissible B.1.617.2...

Mental Health Issues During and After COVID-19 Vaccine Era.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414813
Brain Research Bulletin; Pandey K, Thurman M et. al.

Sep 7th, 2021 - The COVID-19 pandemic has persisted for more than a year, and post-COVID-19 sequelae of neurological complications, including direct and indirect effects on the central nervous system (CNS), have been recognized. There is a plethora of evidence for neurological, cognitive, and emotional deficits in COVID-19 patients. Acute neurological symptoms like neuroinflammation, cognitive impairment, loss...

Origins of SARS-CoV-2: window is closing for key scientific studies.
https://doi.org/10.1038/d41586-021-02263-6 10.1098/rstb.2004.1490 10.1038/s41598-021-91470-2 10.1128/mSphere.00104-21 10.1016/j.cell.2021.06.008 10.1002/smll.202002169
Nature Koopmans M, Daszak P et. al.

Aug 27th, 2021 - Origins of SARS-CoV-2: window is closing for key scientific studies.|2021|Koopmans M,Daszak P,Dedkov VG,Dwyer DE,Farag E,|epidemiology,virology,epidemiology,virology,trends,trends,genetics,isolation & purification,organization & administration,epidemiology,virology,

Causes of death and effect of non-cancer-specific death on rates of overall survival in...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390285
BMC Cancer; Gao J, Chen Y et. al.

Aug 27th, 2021 - The improved prognosis of classic Hodgkin lymphoma (cHL) has been accompanied by elevated risks of non-cancer-specific death (non-CSD). The aim of this study was to verify the occurrence of non-CSD and its effect on rates of overall survival among adult patients with cHL. To ensure sufficient follow-up time, we analyzed retrospective data from patients aged ≥20 years with cHL that was diagnosed...

Prehospital end-tidal carbon dioxide predicts hemorrhagic shock upon emergency departme...
https://doi.org/10.1097/TA.0000000000003312 10.1097/SLA.0b013e3181df0401 10.1016/j.ajem.2020.08.056
The Journal of Trauma and Acute Care Surgery; Bulger N, Harrington B et. al.

Aug 26th, 2021 - In addition to reflecting gas exchange within the lungs, end-tidal carbon dioxide (ETCO2) also reflects cardiac output based on CO2 delivery to the pulmonary parenchyma. We hypothesized that low prehospital ETCO2 values would be predictive of hemorrhagic shock in intubated trauma patients. A retrospective observational study of adult trauma patients intubated in the prehospital setting and tran...

Emerging therapies for rare cutaneous cancers: A systematic review.
https://doi.org/10.1016/j.ctrv.2021.102266
Cancer Treatment Reviews; Garcia A, Nelson K et. al.

Aug 22nd, 2021 - Rare cutaneous cancers require early management given their aggressive nature; however, few therapeutic options exist for managing these rare cancers. To identify emerging therapies for extramammary Paget's disease, Merkel cell carcinoma, sebaceous gland carcinoma, microcystic adnexal carcinoma, Kaposi sarcoma and cutaneous angiosarcoma. A systematic review was conducted using PubMed database f...

Impact of COVID-19 Pandemic on Cancer-Related Hospitalizations in Brazil.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377310
Cancer Control : Journal of the Moffitt Cancer Center; Mafra da Costa A, Ribeiro AL et. al.

Aug 19th, 2021 - Alongside the SARS-CoV-2 (COVID-19) pandemic, Brazil also faces an ongoing rise in cancer burden. In 2020, there were approximately 592 000 new cancer cases and 260 000 cancer deaths. Considering the heterogeneities across Brazil, this study aimed to estimate the impact of the COVID-19 pandemic on cancer-related hospital admissions at a national and regional level. The national, regional, and s...

PET Imaging for Hematologic Malignancies.
https://doi.org/10.1016/j.rcl.2021.05.003
Radiologic Clinics of North America; Hughes NM, Jacene HA

Aug 17th, 2021 - Hematologic malignancies are a broad category of cancers arising from the lymphoid and myeloid cell lines. The 2016 World Health Organization classification system incorporated molecular markers as part of the diagnostic criteria and includes more than 100 subtypes. This article focuses on the subtypes for which imaging with positron emission tomography/computed tomography (PET/CT) has become a...

PET Cardiac Imaging (Perfusion, Viability, Sarcoidosis, and Infection).
https://doi.org/10.1016/j.rcl.2021.05.009
Radiologic Clinics of North America; Manapragada PP, Andrikopoulou E et. al.

Aug 17th, 2021 - Cardiovascular disease is the leading cause of death worldwide. Given the increased availability of radiopharmaceuticals, improved positron emission tomography (PET) camera systems and proven higher diagnostic accuracy, PET is increasingly utilized in the management of various cardiovascular diseases. PET has high temporal and spatial resolution, when compared to Single Photon Emission Computed...