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About 17,265 results

T-Cell Engagers - Modern Immune-Based Therapies for Multiple Myeloma.
https://doi.org/10.1056/NEJMe2209692
The New England Journal of Medicine; Mailankody S, Landgren O

Aug 11th, 2022 - T-Cell Engagers - Modern Immune-Based Therapies for Multiple Myeloma.|2022|Mailankody S,Landgren O,|methods,trends,drug therapy,immunology,therapy,immunology,

The Global Landscape of Esophageal Squamous Cell Carcinoma and Esophageal Adenocarcinom...
https://doi.org/10.1053/j.gastro.2022.05.054
Gastroenterology Morgan E, Soerjomataram I et. al.

Jun 8th, 2022 - The aim of this study was to provide an overview of the burden of esophageal cancer in 185 countries in 2020 and projections for the year 2040. Estimates of esophageal cancer cases and deaths were extracted from the GLOBOCAN database for 2020. Age-standardized incidence and mortality rates were calculated overall, by sex, histologic subtype (adenocarcinoma [AC] and squamous cell carcinoma [SCC]...

Trends in Cancer Mortality Among Black Individuals in the US From 1999 to 2019.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121301
JAMA Oncology; Lawrence WR, McGee-Avila JK et. al.

May 20th, 2022 - Cancer is the second leading cause of mortality in the US. Despite national decreases in cancer mortality, Black individuals continue to have the highest cancer death rates. To examine national trends in cancer mortality from 1999 to 2019 among Black individuals by demographic characteristics and to compare cancer death rates in 2019 among Black individuals with rates in other racial and ethnic...

Zambia Assessment of Tuberculosis (TB) and HIV in the Mines (ZATHIM): implications for ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018205
BMC Public Health; Podewils LJ, Long EF et. al.

Apr 21st, 2022 - Mineworkers in Southern Africa have the highest rates of tuberculosis (TB) among working populations in the world (The World Bank, Benefits and costs associated with reducing tuberculosis among Southern Africa's mineworkers, 2014), making mineworkers a key population for TB program efforts. The current evaluation aimed to characterize mineworkers and former (ex-) mineworkers, and assess knowled...

Hospitalization of Infants and Children Aged 0-4 Years with Laboratory-Confirmed COVID-...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942304
MMWR. Morbidity and Mortality Weekly Report; Marks KJ, Whitaker M et. al.

Mar 18th, 2022 - The B.1.1.529 (Omicron) variant of SARS-CoV-2, the virus that causes COVID-19, has been the predominant circulating variant in the United States since late December 2021.* Coinciding with increased Omicron circulation, COVID-19-associated hospitalization rates increased rapidly among infants and children aged 0-4 years, a group not yet eligible for vaccination (1). Coronavirus Disease 19-Associ...

A Malaria Vaccine for Africa - An Important Step in a Century-Long Quest.
https://doi.org/10.1056/NEJMp2116591
The New England Journal of Medicine; Alonso PL, O'Brien KL

Mar 12th, 2022 - A Malaria Vaccine for Africa - An Important Step in a Century-Long Quest.|2022|Alonso PL,O'Brien KL,|mortality,prevention & control,prevention & control,trends,history,

OPTN/SRTR 2020 Annual Data Report: DOD.
https://doi.org/10.1111/ajt.16976
American Journal of Transplantation : Official Journal Of... Israni AK, Zaun D et. al.

Mar 11th, 2022 - SRTR uses data collected by OPTN to calculate metrics such as donation rate, organ yield, and rate of organs recovered for transplant but not transplanted. In 2020, there were 12,588 deceased donors, an increase from 11,870 in 2019; this number has been increasing since 2010. The number of deceased donor transplants increased to 33,303 in 2020, from 32,313 in 2019; this number has been increasi...

Hospitalizations and Mortality From Non-SARS-CoV-2 Causes Among Medicare Beneficiaries ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908076
JAMA Network Open; Dang A, Thakker R et. al.

Mar 10th, 2022 - The increased hospital mortality rates from non-SARS-CoV-2 causes during the SARS-CoV-2 pandemic are incompletely characterized. To describe changes in mortality rates after hospitalization for non-SARS-CoV-2 conditions during the COVID-19 pandemic and how mortality varies by characteristics of the admission and hospital. Retrospective cohort study from January 2019 through September 2021 using...

Applications of artificial intelligence (AI) in ovarian cancer, pancreatic cancer, and ...
https://doi.org/10.3233/CBM-210301
Cancer Biomarkers : Section A of Disease Markers; Mikdadi D, O'Connell KA et. al.

Feb 26th, 2022 - Artificial intelligence (AI), including machine learning (ML) and deep learning, has the potential to revolutionize biomedical research. Defined as the ability to "mimic" human intelligence by machines executing trained algorithms, AI methods are deployed for biomarker discovery. We detail the advancements and challenges in the use of AI for biomarker discovery in ovarian and pancreatic cancer....

Histoplasmosis in Africa: Current perspectives, knowledge gaps, and research priorities.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8870498
PLoS Neglected Tropical Diseases; Ocansey BK, Kosmidis C et. al.

Feb 25th, 2022 - Histoplasmosis is a chronic granulomatous disease caused by the thermally dimorphic fungus Histoplasma capsulatum. The 2 variants Histoplasma capsulatum var. capsulatum (Hcc) and Histoplasma capsulatum var. duboisii (Hcd) causes infection in humans and commonly termed classical or American histoplasmosis and African histoplasmosis, respectively. Histoplasma capsulatum var. farciminosum (Hcf) af...

Hospitalizations of Children and Adolescents with Laboratory-Confirmed COVID-19 - COVID...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8853476
MMWR. Morbidity and Mortality Weekly Report; Marks KJ, Whitaker M et. al.

Feb 18th, 2022 - The first U.S. case of COVID-19 attributed to the Omicron variant of SARS-CoV-2 (the virus that causes COVID-19) was reported on December 1, 2021 (1), and by the week ending December 25, 2021, Omicron was the predominant circulating variant in the United States.* Although COVID-19-associated hospitalizations are more frequent among adults,† COVID-19 can lead to severe outcomes in children and a...

Secondary primary malignancy in patients with head and neck squamous cell carcinoma: 27...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846538
PloS One; Wang SW, Chan LP et. al.

Feb 16th, 2022 - The survival rate of head and neck squamous cell carcinoma (HNSCC) patients with secondary primary malignancy (SPM) showed no significant improvement for decades, however, the impact of advances in diagnostic tools is rarely mentioned. This study investigated the clinical characteristic of HNSCC with SPM over a 27-year period especially from the perspective of diagnostic tools. This study evalu...

Trends in Sentinel Lymph Node Biopsies in Patients With Inflammatory Breast Cancer in t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837909
JAMA Network Open; Sosa A, Lei X et. al.

Feb 12th, 2022 - The standard of care for inflammatory breast cancer (IBC) is neoadjuvant chemotherapy, total mastectomy with axillary lymph node dissection (ALND), and postmastectomy radiation therapy. Existing studies suggest that sentinel lymph node biopsy (SLNB) may not be reliable in IBC. The use and frequency of SLNB in women with IBC is not well characterized. To determine the frequency and temporal tren...

Progress Toward Rubella and Congenital Rubella Syndrome Control and Elimination - World...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830626
MMWR. Morbidity and Mortality Weekly Report; Zimmerman LA, Knapp JK et. al.

Feb 11th, 2022 - Rubella virus is a leading cause of vaccine-preventable birth defects and can cause epidemics. Although rubella virus infection usually produces a mild febrile rash illness in children and adults, infection during pregnancy, especially during the first trimester, can result in miscarriage, fetal death, stillbirth, or an infant born with a constellation of birth defects known as congenital rubel...

A method for estimating the impact of new vaccine technologies on vaccination coverage ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8830667
PloS One; Davis B, Krautmann M et. al.

Feb 11th, 2022 - Vaccines are one of the most cost-effective tools for improving human health and well-being. The impact of a vaccine on population health is partly determined by its coverage rate, the proportion of eligible individuals vaccinated. Coverage rate is a function of the vaccine presentation and the population in which that presentation is deployed. This population includes not only the individuals ...

SARS-CoV-2 Prevention Measures Concomitantly Attenuate Methicillin-Resistant Staphyloco...
https://doi.org/10.1177/00099228211067898
Clinical Pediatrics; Dalabih A, Young HL et. al.

Feb 9th, 2022 - SARS-CoV-2 Prevention Measures Concomitantly Attenuate Methicillin-Resistant Staphylococcus aureus Infection Rates.|2022|Dalabih A,Young HL,Frenner RA,Stroud MH,Boyanton BL,|epidemiology,epidemiology,prevention & control,methods,standards,trends,pathogenicity,methods,standards,trends,epidemiology,prevention & control,

Clinical evaluation of flat peripheral curve design with aspherical-curve and multi-cur...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824338
PloS One; Kumanomido T, Kamiya K et. al.

Feb 9th, 2022 - Aspherical- and multi-curve rigid gas-permeable hard contact lenses (HCLs) have a flattened curve in the peripheral zone and are mostly used for patients with keratoconus who cannot wear glasses, soft contact lenses, or spherical HCLs. In this retrospective study, a total of 95 eyes of 77 patients who used aspherical- or multi-curve HCLs (mean age: 40.0 ± 11.0 years) were evaluated. This study ...

Intergeneration transfer of diet patterns? Parental self-report of diet and their repor...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824362
PloS One; Kranz S, Lukacs J et. al.

Feb 9th, 2022 - Autism Spectrum Disorder (ASD) affects two percent of American children and often results in neophobia, hypersensitivity to foods, and firmly set food preferences, leading to higher proportions of individuals suffering from diet-related chronic diseases. Our objective was to conduct an explorative pilot study to examine parents' perception of food intake for themselves and their young adult chi...

A decade of data: Adolescent vaccination in the vaccine safety datalink, 2007 through 2...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813203
Vaccine Irving SA, Groom HC et. al.

Feb 8th, 2022 - Between May 2005 and March 2007, three vaccines were recommended by the Advisory Committee on Immunization Practices for routine use in adolescents in the United States: quadrivalent meningococcal conjugate vaccine (MenACWY), tetanus, diphtheria and acellular pertussis vaccine (Tdap), and human papillomavirus vaccine (HPV). Understanding historical adolescent vaccination patterns may inform fut...

Racial/ethnic disparities in hepatocellular carcinoma incidence and mortality rates in ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352816
Hepatology (Baltimore, Md.); Alvarez CS, Petrick JL et. al.

Feb 7th, 2022 - HCC is characterized by racial/ethnic disparities in rates. Recent USA reports suggest that incidence has begun to decline, but it is not clear whether the declines have occurred among all groups, nor whether mortality has declined. Thus, the current study examined USA incidence and mortality between 1992 and 2018. HCC incidence and incidence-based mortality data from the Surveillance, Epidemio...