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About 5,515 results

17-Hydroxyprogesterone, Urine
https://emedicine.medscape.com/article/2097997-overview

Jun 23rd, 2022 - Reference Range The reference range of urinary 17-hydroxyprogesterone (17-OHPG) in children is as follows: [1, 2, 3] Age 3 days to 1 year: Up to 50 ng/24 hours Age 1-8 years: Up to 300 ng/24 hours The following is the reference of urinary 17-OHPG in adults: Males: Up to 2 µg/24 hours Females: Up to 4.5 µg/24 hours Next: Interpretation Elevated urinary 17-hydroxyprogesterone (17-OHPG) levels are...

17-Hydroxyprogesterone, Urine
http://emedicine.medscape.com/article/2097997-overview

Jun 23rd, 2022 - Reference Range The reference range of urinary 17-hydroxyprogesterone (17-OHPG) in children is as follows: [1, 2, 3] Age 3 days to 1 year: Up to 50 ng/24 hours Age 1-8 years: Up to 300 ng/24 hours The following is the reference of urinary 17-OHPG in adults: Males: Up to 2 µg/24 hours Females: Up to 4.5 µg/24 hours Next: Interpretation Elevated urinary 17-hydroxyprogesterone (17-OHPG) levels are...

Urine Test Detects SARS-CoV-2 Antibodies.
https://doi.org/10.1001/jama.2022.9512
JAMA Larkin HD

Jun 15th, 2022 - Urine Test Detects SARS-CoV-2 Antibodies.|2022|Larkin HD,|urine,diagnosis,immunology,urine,methods,immunology,methods,

Performance of a rapid immuno-chromatographic test (Schistosoma ICT IgG-IgM) for detect...
https://doi.org/10.1371/journal.pntd.0010463
PLoS Neglected Tropical Diseases; Hoermann J, Kuenzli E et. al.

May 28th, 2022 - Schistosomiasis, an acute and chronic parasitic disease caused by human pathogenic Schistosoma species, is a neglected tropical disease affecting more than 220 million people worldwide. For diagnosis of schistosomiasis, stool and urine microscopy for egg detection is still the recommended method, however sensitivity of these methods is limited. Therefore, other methods like molecular detection ...

Vitronectin, a Novel Urinary Proteomic Biomarker, Promotes Cell Pyroptosis in Juvenile ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020974
Mediators of Inflammation; Zhang S, Pan W et. al.

Apr 26th, 2022 - Identifying new markers of juvenile systemic lupus erythematosus (JSLE) is critical event to predict patient stratification and prognosis. The aim of the present study is to analyze alteration of urinary protein expression and screen potential valuable biomarkers in juvenile systemic lupus erythematosus (JSLE). The urine was collected from the patients with or without JSLE and detected by mass ...

Stability of serial platelet and urine protein measurements in patients receiving nusin...
https://doi.org/10.1002/mus.27564
Muscle & Nerve; Nagarajan EK, Özütemiz C et. al.

Apr 26th, 2022 - Patients undergoing nusinersen treatment for spinal muscular atrophy are subject to measurements of platelet count and urine protein before each injection due to concern for platelet depletion and renal dysfunction according to the prescribing information. These tests may be uncomfortable or inconvenient and may cause delays in treatment. However, it is still unclear whether these values have b...

Urinary galectin-3 binding protein (G3BP) as a biomarker for disease activity and renal...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8962213
Arthritis Research & Therapy; Ding H, Shen Y et. al.

Mar 30th, 2022 - There is an urgent need to identify novel biomarkers of LN to reflect renal histological changes. This study aims to investigate urinary G3BP levels in LN patients and their association with renal disease activity both clinically and pathologically. This is a cross-sectional study. A total of 119 lupus nephritis patients were recruited. Thirty patients with chronic kidney diseases (CKD) and 27 ...

Predicting treatment response and clinicopathological findings in lupus nephritis with ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912200
PloS One; Ngamjanyaporn P, Worawichawong S et. al.

Mar 11th, 2022 - There is a need for sensitive and specific biomarkers to predict kidney damage and therapeutic response in lupus nephritis (LN). Monocyte chemoattractant protein-1 (MCP-1) and epidermal growth factor (EGF) are cytokines with divergent roles. EGF or EGF/MCP1 ratio have been shown to correlate with prognosis in primary glomerulonephritis, but there is limited information in lupus nephritis (LN). ...

Implementation of tuberculosis and cryptococcal meningitis rapid diagnostic tests among...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897937
BMC Infectious Diseases; Kanyama C, Chagomerana MB et. al.

Mar 7th, 2022 - Cryptococcal meningitis (CM) and tuberculosis (TB) remain leading causes of hospitalization and death amongst people living with HIV, particularly those with advanced HIV disease. In hospitalized patients, prompt diagnosis of these diseases may improve patient outcomes. The advanced HIV rapid diagnostic tests such as determine TB urine lipoarabinomannan lateral flow assay (urine LAM), urine X-p...

Delayed diagnosis of urinary tuberculosis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9053974
CMAJ : Canadian Medical Association Journal = Journal De ... Dhersin R, Bazeries P et. al.

Mar 2nd, 2022 - Delayed diagnosis of urinary tuberculosis.|2022|Dhersin R,Bazeries P,Chenouard R,Dubée V,|etiology,complications,diagnosis,drug therapy,urine,microbiology,

Utility of urine lipoarabinomannan (LAM) in diagnosing mycobacteria infection among hos...
https://doi.org/10.1016/j.ijid.2022.02.046
International Journal of Infectious Diseases : IJID : Off... Liu D, Gu L et. al.

Feb 28th, 2022 - Cross-reactivity with nontuberculous mycobacteria (NTM) species might limit the use of urine lipoarabinomannan (LAM) test to diagnose tuberculosis (TB) in people living with HIV (PLWH). This study aimed to investigate the utility of the LAM test among hospitalized HIV-positive patients. This prospective study enrolled HIV-positive inpatients with any TB symptom or seriously ill patients with ad...

Immune cell profiles of patients with interstitial cystitis/bladder pain syndrome.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862517
Journal of Translational Medicine; Moldwin RM, Nursey V et. al.

Feb 24th, 2022 - Interstitial cystitis/bladder pain syndrome (IC/BPS) is a disorder characterized by bladder pain upon filling which severely affects quality of life. Clinical presentation can vary. Local inflammatory events typify the clinical presentation of IC/BPS patients with Hunner lesions (IC/BPS-HL). It has previously been proposed that B cells are more prevalent in HL, but understanding their exact rol...

Altered kidney function induced by SARS-CoV-2 infection and acute kidney damage markers...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8856025
Renal Failure; Temiz MZ, Hacibey I et. al.

Feb 18th, 2022 - Literature with regard to coronavirus disease 2019 (COVID-19) associated morbidities and the risk factors for death are still emerging. In this study, we investigated the presence of kidney damage markers and their predictive value for survival among hospitalized subjects with COVID-19. Forty-seven participants was included and grouped as: 'COVID-19 patients before treatment', 'COVID-19 patient...

3-Hydroxyisobutyric acid dehydrogenase deficiency: Expanding the clinical spectrum and ...
https://doi.org/10.1002/jimd.12486
Journal of Inherited Metabolic Disease; Sasarman F, Ferdinandusse S et. al.

Feb 18th, 2022 - A deficiency of 3-hydroxyisobutyric acid dehydrogenase (HIBADH) has been recently identified as a cause of primary 3-hydroxyisobutyric aciduria in two siblings; the only previously recognized primary cause had been a deficiency of methylmalonic semialdehyde dehydrogenase, the enzyme that is immediately downstream of HIBADH in the valine catabolic pathway and is encoded by the ALDH6A1 gene. Here...

Inflammatory biomarkers in the evaluation of pediatric endogenous Cushing syndrome.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059943
European Journal of Endocrinology; Wurth R, Rescigno M et. al.

Feb 17th, 2022 - Inflammatory biomarkers, such as absolute neutrophil and lymphocyte counts, neutrophil-to-lymphocyte ratio (NLR), platelet (PLT)-to-lymphocyte ratio (PLR) and monocyte-to-lymphocyte ratio (MLR), are associated with the progression and development of several disorders. Although patients with Cushing syndrome (CS) have immunosuppression with altered leucocyte counts, the profile of the inflammato...

Mechanistic modelling of enzyme-restoration effects of new recombinant liver-targeted p...
https://doi.org/10.1111/bph.15821
British Journal of Pharmacology; Vera-Yunca D, Córdoba KM et. al.

Feb 17th, 2022 - Acute intermittent porphyria (AIP) is a rare disease caused by a genetic mutation in the hepatic activity of the porphobilinogen-deaminase. We aimed to develop a mechanistic model of the enzymatic restoration effects of a novel therapy based on the administration of different formulations of recombinant human-PBGD (rhPBGD) linked to the ApoAI lipoprotein. This fusion protein circulates in blood...

Persistence of Schistosoma haematobium transmission among school children and its impli...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846507
PloS One; Mushi V, Zacharia A et. al.

Feb 16th, 2022 - Despite twelve rounds of school-based preventive chemotherapy for schistosomiasis in endemic areas of Tanzania such as Mtama district, Lindi: the burden of Schistosoma haematobium infection has remained highly conceivable due to re-infections. The factors associated with continuity of S.haematobium transmission in Mtama district, Lindi have not been fully established. This study investigated th...

Transmission Of Tuberculosis Among illicit drug use Linkages (TOTAL): A cross-sectional...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846525
PloS One; Carney T, Rooney JA et. al.

Feb 16th, 2022 - People who use illicit drugs (PWUDs) have been identified as a key at-risk group for tuberculosis (TB). Examination of illicit drug use networks has potential to assess the risk of TB exposure and disease progression. Research also is needed to assess mechanisms for accelerated TB transmission in this population. This study aims to 1) assess the rate of TB exposure, risk of disease progression,...

Oxalobacter formigenes treatment confers protective effects in a rat model of primary h...
https://doi.org/10.1007/s00240-022-01310-9 10.1016/j.ekir.2020.06.021 10.1056/NEJMra1301564 10.1016/j.kint.2019.08.018 10.1016/j.kint.2021.03.031 10.1016/j.ekir.2018.07.020 10.1038/ki.2011.287 10.2215/CJN.14730920 10.1007/BF00446731 10.1681/ASN.2007101058 10.1016/S0022-5347(05)65817-X 10.1016/j.soard.2017.03.014 10.1038/sj.ki.5000162 10.1681/ASN.2016020132 10.1016/0009-8981(82)90080-8 10.1016/j.juro.2012.12.004 10.1016/S0723-2020(99)80053-8 10.1128/aem.63.7.2884-2896.1997 10.1111/j.1523-1755.2005.00735.x 10.1152/ajprenal.90727.2008 10.1016/S0022-5347(05)65127-0 10.1093/ndt/gfp418 10.1002/ptr.3196 10.2215/CJN.02810315 10.1093/toxsci/62.1.10 10.21037/atm.2016.12.70 10.1016/j.juro.2007.06.045 10.1371/journal.pone.0222393 10.1007/s00240-014-0728-2
Urolithiasis Verhulst A, Dehmel B et. al.

Feb 6th, 2022 - In primary hyperoxaluria, increased hepatic oxalate production sometimes leads to severe nephrocalcinosis and early end-stage kidney disease. Oral administration of Oxalobacter formigenes (O. formigenes), an oxalate-degrading bacterium, is thought to derive oxalate from systemic sources by inducing net enteric oxalate secretion. Here, the impact of O. formigenes on nephrocalcinosis was investig...

Urine sodium to urine creatinine ratio as a marker of total body sodium in infants with...
https://doi.org/10.1016/j.jpedsurg.2021.12.035
Journal of Pediatric Surgery; Choi S, Casey L et. al.

Jan 27th, 2022 - Urine sodium (UNa) is a measure of total body sodium in infants with intestinal failure (IF) but can be misleading as it does not reflect volume status. Urine sodium to urine creatinine ratio (UNa:UCr) may offer a more accurate measure, but is not routinely used. This study compares UNa:UCr to UNa as a maker of sodium status in infants with IF. A retrospective review of infants with IF, from a ...