Feb 20th, 2022 - WAIKOLOA, Hawaii — In this Healio Video Perspective from Hawaiian Eye 2022, Andrew G. Lee, MD, discusses ways to differentiate between glaucoma and nonglaucomatous neuro-ophthalmic disease.
Feb 19th, 2022 - WAIKOLOA, Hawaii — In this Healio Video Perspective from Hawaiian Eye 2022, Ronald R. Krueger, MD, discusses strategies for early detection of keratoconus and the benefits of performing cross-linking at an early stage.
Feb 9th, 2022 - WAIKOLOA, Hawaii — In this Healio Video Perspective from Hawaiian Eye 2022, Laura M. Periman, MD, discusses superior limbic keratoconjunctivitis and the potential use of neuromodulators to ease patients’ symptoms.
Feb 7th, 2022 - WAIKOLOA, Hawaii — With several good MIGS options, the choice often comes down to matching the procedure with the patient, according to a presentation at Hawaiian Eye 2022. John Berdahl, MD, said devices such as the Hydrus microstent (Ivantis/Alcon) and the iStent (Glaukos) have shown efficacy in reducing IOP and medications in patients with glaucoma. “So, how do you choose?” Berdahl said. “I a...
Feb 3rd, 2022 - WAIKOLOA, Hawaii — Systemic effects of anti-VEGF in retinopathy of prematurity have not been ruled out, so it may be wise to use bevacizumab in lower doses or switch to agents with less systemic exposure, according to one presenter. “The BEAT-ROP study demonstrated a beneficial effect for bevacizumab vs. laser in the treatment of zone I, stage 3+ ROP. But one thing I didn’t like was the complet...
Jan 26th, 2022 - WAIKOLOA, Hawaii — In this Healio Video Perspective from Hawaiian Eye 2022, Kathryn M. Hatch, MD, explains why cornea specialists strive for “one and done” when treating keratoconus and other epithelial defects with collagen cross-linking.
Jan 25th, 2022 - WAIKOLOA, Hawaii — In this Healio Video Perspective from Hawaiian Eye 2022, Michael Greenwood, MD, discusses the benefits of adding endoscopic cyclophotocoagulation to any minimally invasive glaucoma surgery.
Jan 21st, 2022 - WAIKOLOA, Hawaii — Surgeons need to consider the risks and possible refractive outcomes before implanting a premium IOL in a patient with glaucoma, according to a presentation at Hawaiian Eye 2022. Nathan Radcliffe, MD, said that when a patient with glaucoma who already has a premium IOL experiences a problem, the IOL is rarely the issue. “I never remove the premium IOL because as bad as the gl...
Jan 20th, 2022 - WAIKOLOA, Hawaii — Ophthalmologists should consider co-management of other diseases when treating progressive glaucoma, according to a speaker here. “I think that we need to remind ourselves, even as we rush through clinic, to think about the linkage to common disease that puts the optic nerve at risk,” Jeffrey L. Goldberg, MD, PhD, said at Hawaiian Eye 2022. To aid with co-management, he said,...
Jan 20th, 2022 - WAIKOLOA, Hawaii — Clinical research, personal experience, physician skill set, patient factors and goals all influence the decision to perform trabeculectomy or use a tube shunt, a speaker said here at Hawaiian Eye 2022. “Individualize the treatment choice to the patient in front of you,” Brian E. Flowers, MD, said. If the IOP target is low or if the patient is younger or has medication tolera...
Jan 19th, 2022 - WAIKOLOA, Hawaii — Fluorescence imaging can be an important tool for early detection of retinal diseases, according to a presentation at Retina 2022. Rishi P. Singh, MD, said that technologies such as fundus autofluorescence (FAF), fluorescence lifetime imaging ophthalmoscopy (FLIO) and oxidized flavoprotein fluorescence (FPF) provide opportunities to identify cell dysfunction before it occurs....
Jan 19th, 2022 - WAIKOLOA, Hawaii — Visual field testing is important for detecting progression in patients with glaucoma, but some may have difficulty with the test process, according to a speaker here. “This is very true for the full threshold patterns, which require 15 minutes per eye,” Monica Ertel, MD, PhD, said at Hawaiian Eye 2022. Ertel discussed developments in visual field strategies, including visual...
Jan 19th, 2022 - WAIKOLOA, Hawaii — Keep the cornea in mind and protect the endothelium when managing pseudoexfoliation glaucoma during cataract surgery, a presenter said here. “Consider femto if at all possible to decrease the ultrasound and combine with angle surgery, but skip the implants to save the cornea,” Malik Y. Kahook, MD, said at Hawaiian Eye 2022. The second key is to target the angle first and earl...
Jan 19th, 2022 - WAIKOLOA, Hawaii — In a series of published reports, the Classification of Atrophy Meeting group provided consensus-based imaging parameters for multimodal assessment of geographic atrophy. The group also revised the definitions of specific features of geographic atrophy (GA) and identified features that may predict progression to atrophy. “In the first CAM report, we described the imaging moda...
Jan 19th, 2022 - WAIKOLOA, Hawaii — At Hawaiian Eye 2022, I. Paul Singh, MD, discusses some of the advantages of the use of Durysta intracameral bimatoprost injection to lower IOP in patients with glaucoma. “What’s interesting about Durysta now, having about a year and a half experience with it is that although it releases bimatoprost for 4 months, the duration of effect in some patients can be 6 months, 9 mont...
Jan 18th, 2022 - WAIKOLOA, Hawaii — Several pathways are under investigation for the treatment of dry age-related macular degeneration, according to a presentation at Retina 2022. “The big issue for us researchers is we don’t have a good animal model to test anything,” Peter K. Kaiser, MD, said. “We don’t have preclinical models that inform us if a drug is going to work or not because the animal that we use are...
Jan 18th, 2022 - WAIKOLOA, Hawaii — Just past the 15-year anniversary of the cefuroxime ESCRS trial, debate regarding antibiotic prophylaxis for endophthalmitis after cataract surgery continues. “When you have something controversial, it's nice to see what our colleagues are doing,” David F. Chang, MD, said at Hawaiian Eye 2022. To that end, surveys of ASCRS members conducted in 2007, 2014 and 2021 published in...
Jan 18th, 2022 - WAIKOLOA, Hawaii — In this Healio Video Perspective from Hawaiian Eye 2022, John Berdahl, MD, of Vance Thompson Vision in Sioux Falls, South Dakota, spoke about premium and toric IOLs in patients with glaucoma. “I was actually quite surprised in an informal poll of the audience at how many surgeons did premium IOLs,” Berdahl said. “The vast majority of hands went up, but they actually stayed up...
Jan 17th, 2022 - WAIKOLOA, Hawaii — Diagnosing and treating ocular surface disease preoperatively is one of the elements that contribute to elevated patient satisfaction postoperatively, Marjan Farid, MD, said at Hawaiian Eye 2022. “We know that 50% of patients, at least, who come in for cataract surgery are asymptomatic, but at least 80% of those patients have at least one sign of dry eye disease,” Farid said ...
Jan 17th, 2022 - WAIKOLOA, Hawaii — The landscape of ocular oncology is “rapidly evolving” in a way similar to medical oncology, a speaker said during a presentation here. At Hawaiian Eye 2022, Basil K. Williams Jr., MD, discussed how anterior segment OCT can be a “valid help adjunct” to clinical exams, although it is not a replacement for them. OCT can also help physicians differentiate between different lesio...
Jan 17th, 2022 - WAIKOLOA, Hawaii — Medicare payment changes, ASC payment rates and new FDA approved drugs were a few of the topics discussed in a presentation on 2022 updates for ophthalmic practices at Hawaiian Eye 2022. Paul M. Larson, MBA, MMSC, COMT, CPC, COE, CPMA, a senior consultant from Corcoran Consulting Group, said that the Medicare Physician Fee Schedule was just updated a few weeks ago. “With the ...
Jan 16th, 2022 - WAIKOLOA, Hawaii — It is important for physicians to consider “the perils that dwell” in the diagnostic management of patients with uveitis, Steven Yeh, MD, said during a presentation at Hawaiian Eye 2022. “With these patients being very complex oftentimes, we really just don’t want to miss something,” Yeh said. To better identify “the pearls amongst the perils” in uveitis diagnosis, it is impo...
May 24th, 2021 - WAILEA, Hawaii — In this Hawaiian Eye 2021 video, Savak “Sev” Teymoorian, MD, MBA, explains how Dextenza (dexamethasone, Ocular Therapeutix) intracanalicular inserts can reduce drop burden in patients with glaucoma after cataract surgery.
May 21st, 2021 - WAILEA, Hawaii — In this video from Hawaiian Eye 2021, Andrew G. Lee, MD, discusses the important questions ophthalmologists should ask patients with optic neuritis to identify neuromyelitis optica spectrum disorder.
May 21st, 2021 - WAILEA, Hawaii — In this video at Hawaiian Eye 2021, Savak Teymoorian, MD, MBA, discusses how the Durysta bimatoprost implant 10 µg from Allergan obviates the need for patients with glaucoma to instill drops.
May 18th, 2021 - WAILEA, Hawaii — The COVID-19 pandemic changed the way physicians monitor age-related macular degeneration, and Nancy M. Holekamp, MD, believes those changes are here to stay. “We all learned that remote monitoring of our patients is desirable, even if there isn’t a pandemic,” she said in her presentation at Retina 2021. “It currently exists with monitoring patients with intermediate AMD, and t...
May 14th, 2021 - WAILEA, Hawaii — New research using liquid biopsy presents a new opportunity for treating retinoblastoma. Currently, retinoblastoma is diagnosed clinically, without biopsy, to avoid extraocular tumor seeding. In ongoing research, Jesse L. Berry, MD, of USC Roski Eye Institute, and colleagues are finding potential for using aqueous humor, obtained safely, as a means of diagnosing retinoblastoma,...
May 14th, 2021 - WAILEA, Hawaii — In this video from Hawaiian Eye, I. Paul Singh, MD, discusses how innovative technology has changed his definition of controlled glaucoma.
May 13th, 2021 - WAILEA, Hawaii — Glaucoma patients may ask for ways to monitor IOP between visits, but ophthalmologists should weigh benefits and drawbacks of at-home monitoring options, according to speakers at Hawaiian Eye 2021. “I have that question all the time, actually,” Sahar Bedrood, MD, PhD, said. “Some of my patients are significantly worried, so they come in.” Options for at-home eye care include re...
May 13th, 2021 - WAILEA, Hawaii — M. Bruce Shields, MD, was awarded the Philip M. Corboy, MD, Memorial Award for Distinguished Service to Ophthalmology at Hawaiian Eye 2021. Shields was unable to attend the meeting but accepted the award by way of a recorded video. “I sure wish we could be with you, but I’m grateful to the organizing committee of the Hawaiian Eye meeting that we can at least join you virtually,...
May 12th, 2021 - WAILEA, Hawaii — In this video from Hawaiian Eye 2021, Sahar Bedrood, MD, PhD, discusses how she has incorporated the iStent inject (Glaukos) into her practice, patient selection and the benefits of using the device in those with glaucoma.
May 12th, 2021 - WAILEA, Hawaii — In this video from Hawaiian Eye, Thomas W. Samuelson, MD, discusses the nuanced decision-making that goes into deciding which surgical interventions to use in patients with glaucoma who are also in need of cataract surgery.
May 11th, 2021 - WAILEA, Hawaii — In this video from Hawaiian Eye, Brandon D. Ayres, MD, discusses why patients with keratoconus and cataract should receive corneal collagen crosslinking prior to cataract surgery.
May 10th, 2021 - WAILEA, Hawaii — At Hawaiian Eye 2021, Deborah G. Ristvedt, DO, discusses how to implement minimally invasive glaucoma surgery techniques in a surgical practice using the newest technologies.
Jun 21st, 2022 - The hypothesis is that the addition of daratumumab administered SC to standard MM regimens will improve responses compared to response data observed in completed phase 3 studies without daratumumab. Disease evaluations will include measurements of myeloma proteins, bone marrow examinations, skeletal surveys, assessment of extramedullary plasmacytomas, and measurements of serum calcium corrected...
https://doi.org/10.1007/s10067-022-06164-5 10.1056/NEJMra1505557 10.1111/1756-185X.12283 10.1093/rheumatology/ker349 10.1080/03009742.2019.1672783 10.3899/jrheum.171034 10.2174/1574887113666180314105511 10.1136/annrheumdis-2014-206824 10.1161/CIRCRESAHA.115.306883 10.1016/j.mayocp.2018.01.016 10.1007/s11695-013-0924-0 10.1016/S0140-6736(16)00271-3 10.1046/j.1467-789x.2001.00026.x 10.1249/MSS.0000000000001074 10.1111/obr.12422 10.1016/j.archger.2016.02.004 10.1016/j.physio.2015.05.003 10.1136/ard.51.1.35 10.1186/s13075-019-1810-5 10.1186/s13075-020-02350-5 10.1002/art.21972 10.3109/03009749309095105 10.1016/0002-9343(85)90465-6 10.1152/jappl.19126.96.36.199 10.1186/1471-2474-15-305 10.1097/00005650-199206000-00002 10.1111/sms.12611 10.1002/art.23568 10.1136/ard.2009.122259 10.1146/annurev.nutr.21.1.323 10.1002/oby.22476 10.1016/j.bone.2009.10.013 10.1002/art.33394 10.1001/jama.2009.681 10.1080/00913847.2019.1623995 10.1016/j.semarthrit.2004.07.010 10.3945/an.116.014506 10.1007/s11926-012-0263-5 10.1002/acr.24126 10.7762/cnr.2019.8.2.148 10.1186/s12905-019-0864-5
Clinical Rheumatology; Bilberg A, Larsson I et. al.
Jun 2nd, 2022 - To evaluate the effects of weight loss treatment on physical fitness in patients with psoriatic arthritis (PsA) and obesity compared to matched controls. In total, 46 patients with PsA (CASPAR) and BMI ≥ 33 kg/m2 and 52 obese persons were included in this 12-month prospective open intervention study with a very low energy diet (640 kcal/day), followed by structured reintroduction of an energy-r...
Arthritis & Rheumatology (Hoboken, N.J.); Fraenkel L, Bathon JM et. al.
Jun 9th, 2021 - To develop updated guidelines for the pharmacologic management of rheumatoid arthritis. We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to rate the certainty of evidence. A voting panel comprising c...
Dec 30th, 2022 - Fluconazole tablets are indicated for the treatment of: Vaginal candidiasis (vaginal yeast infections due to Candida). Oropharyngeal and esophageal candidiasis. In open noncomparative studies of relatively small numbers of patients, fluconazole tablets were also effective for the treatment of Candida urinary tract infections, peritonitis, and systemic Candida infections including candidemia, di...
MedPage Today; Fiore K.
Jun 29th, 2022 - The U.S. is expanding its monkeypox vaccination strategy to include those with a presumed exposure to monkeypox, not just a confirmed exposure, federal officials announced Tuesday evening. The new strategy takes into account the limited doses of the preferred vaccine, Jynneos, according to CDC Director Rochelle Walensky, MD.
Nature Mallapaty S.
Jun 29th, 2022 - First there were sneezing hamsters, now sneezing cats. A team in Thailand reports the first solid evidence of a pet cat infecting a person with SARS-CoV-2 — adding felines to the list of animals that can transmit the virus to people.
BMJ Stokel-Walker C.
Jun 29th, 2022 - What happens to SARS-CoV-2 when it enters the body, and how long does it linger? Nearly three years since the virus was first discovered, this is still a mystery.
Emerging Infectious Diseases; Matsumura Y, Nagao M et. al.
Jun 17th, 2022 - Household transmission is a primary source of SARS-CoV-2 spread. We used COVID-19 epidemiologic investigation data and viral genome analysis data collected in the city of Kyoto, Japan, during January 2020–June 2021 to evaluate the effects of different settings and viral strains on SARS-CoV-2 transmission. Epidemiologic investigations of 5,061 COVID-19 cases found that the most common category f...
Nature Marshall M.
Jun 9th, 2022 - Researchers are finally making headway in understanding how the SARS-CoV-2 coronavirus causes loss of smell. And a multitude of potential treatments to tackle the condition are undergoing clinical trials, including steroids and blood plasma.
Nature Kozlov M.
Jun 8th, 2022 - As global monkeypox cases continue to rise, public-health officials and researchers are questioning whether the current outbreaks can be contained. The World Health Organization (WHO) has said that the situation is unlikely to escalate into a full-blown pandemic. But there are now more than 1,000 confirmed infections in nearly 30 countries where outbreaks do not usually occur (see ‘Unusual spre...
Metabolism Open; Amanatidou A, .
Jun 1st, 2022 - Vaccination programs against SARS-CoV-2 constitute the mainstay of public health interventions against the global COVID-19 pandemic. Currently available vaccines have shown 90% or better rates of protection against severe disease and mortality. Barely a year after vaccines became available, the Omicron variant and its unprecedented speed of transmission has posed a new challenge.
World Health Organization (WHO)
Jun 1st, 2022 - The World Health Organization (WHO) with the support of Strategic Advisory Group of Experts (SAGE) on Immunization and its COVID-19 Vaccines Working Group, continues to review the emerging evidence on the increasing seroprevalence rates against SARS-CoV-2 globally and the characteristics and potential benefits of hybrid immunity. This statement reflects the current understanding of hybrid immun...
The Journal of Allergy and Clinical Immunology; Seibold MA, .
May 31st, 2022 - Whether children and people with asthma and allergic diseases are at increased risk for SARS-CoV-2 infection is unknown.
Nature Reardon S.
May 25th, 2022 - Vaccination against SARS-CoV-2 lowers the risk of long COVID after infection by only about 15%, according to a study of more than 13 million people1. That’s the largest cohort that has yet been used to examine how much vaccines protect against the condition, but it is unlikely to end the uncertainty.
MedPage Today; Walker M.
May 24th, 2022 - With one confirmed case and four presumptive cases of monkeypox in the U.S., clinicians should continue to be on high alert if their patients report new onset of rash, especially in the genital or perianal area, CDC staff said Monday. The one confirmed case in Massachusetts had over 200 close contacts, the majority of whom were healthcare workers, said Capt. Jennifer McQuiston, DVM, deputy d...
World Health Organization (WHO)
May 19th, 2022 - Monkeypox is a viral zoonosis (a virus transmitted to humans from animals) with symptoms similar to those seen in the past in smallpox patients, although it is clinically less severe. With the eradication of smallpox in 1980 and subsequent cessation of smallpox vaccination, monkeypox has emerged as the most important orthopoxvirus for public health. Monkeypox primarily occurs in central and wes...