×
About 1,898,500 results

Germline Variants Identified in Patients with Early-onset Renal Cell Carcinoma Referred for Germline Genetic Testing
https://pubmed.ncbi.nlm.nih.gov/34654685/
European Urology Oncology; Truong H

Oct 12th, 2021 - Despite guidelines recommending genetic counseling for patients with early-onset renal cell carcinoma (RCC), studies interrogating the spectrum of germline mutations and clinical associations in patients with early-onset RCC are lacking.

Moxifloxacin - moxifloxacin solution/ drops-Lupin Pharmaceuticals, Inc.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ae77e219-8af9-4aa4-96d3-05c9726a1d3c

Jun 6th, 2022 - Moxifloxacin ophthalmic solution, 0.5% is a topical fluoroquinolone anti- infective indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms: Corynebacterium species*, Micrococcus luteus*, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus warneri*, Streptococcus pneumonia...

Surveillance of SARS-CoV-2 in the environment and animal samples of the Huanan Seafood Market
https://www.researchsquare.com/article/rs-1370392/v1
Research Square; Gao G, .

Feb 22nd, 2022 - Emerging in December 2019, coronavirus disease 2019 (COVID-19) eventually became a pandemic and has posed a tremendous threat to global public health. However, the origins of SARS-CoV-2, the causative agent of COVID-19, remain to be determined. It has reported that a certain number of the early case clusters had a contact history with Huanan Seafood Market.

Covid-19: Antibodies after AstraZeneca and Pfizer vaccines decrease with age and are higher in women, data show
https://www.bmj.com/content/376/bmj.o428
BMJ Iacobucci G.

Feb 18th, 2022 - SARS-CoV-2 antibody levels after receiving the AstraZeneca or Pfizer-BioNTech vaccine decrease with age and are higher in females and people with prior infection, show data from the Real-time Assessment of Community Transmission (React-2) study.1

Procentra - dextroamphetamine sulfate solution-Independence Pharmaceuticals, LLC
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1548cce2-fb6b-4f17-8a3b-868933f6c9d6

Jun 1st, 2022 - ProCentra ® (dextroamphetamine sulfate) Oral Solution is indicated in: Narcolepsy Attention Deficit Disorder with Hyperactivity: As an integral part of a total treatment program that typically includes other remedial measures (psychological, educational, social) for a stabilizing effect in pediatric patients (ages 3 years to 16 years) with a behavioral syndrome characterized by the following gr...

Quetiapine fumarate - quetiapine fumarate tablet, extended release-Lupin Pharmaceuticals, Inc.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7803a290-91c0-4e7f-90b5-d2ff33a46cee

Jun 1st, 2022 - Quetiapine extended-release tablet is an atypical antipsychotic indicated for the treatment of: Schizophrenia (1.1) Bipolar I disorder, manic or mixed episodes (1.2) Bipolar disorder, depressive episodes (1.2) Major depressive disorder, adjunctive therapy with antidepressants (1.3) Quetiapine extended-release tablet is indicated for the treatment of schizophrenia. The efficacy of quetiapine ext...

Imatinib mesylate - imatinib mesylate tablet, film coated-Apotex Corp
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0291eca5-7a1d-4a79-30be-252224d96509

May 30th, 2022 - Imatinib mesylate is a kinase inhibitor indicated for the treatment of: • Newly diagnosed adult and pediatric patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) in chronic phase (1.1) • Patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) in blast crisis (BC), accelerated phase (AP), or in chronic phase (CP) after failure of interferon...

Diffuse Bone Marrow Involvement of Multiple Myeloma on 18FPSMA-1007 PET/CT: Is There a ...
https://doi.org/10.1097/RLU.0000000000004286
Clinical Nuclear Medicine; Michalski K, Jilg CA et. al.

May 28th, 2022 - A 71-year-old man presented with chronic anemia (hemoglobin 7.3 g/dL). Further serum analyses showed elevated prostate-specific antigen (13 ng/mL), suggestive of prostate cancer. However, ultrasound-guided transrectal sextant biopsy did not find any evidence of prostate cancer. In order to improve guidance of intended repeated biopsy, [18F]prostate-specific membrane antigen (PSMA) 1007 PET/CT w...

Hypermetabolic Esophagitis Dessicans Superficialis Mimicking Esophageal Cancer on FDG P...
https://doi.org/10.1097/RLU.0000000000004303
Clinical Nuclear Medicine; Mamaliga T, Liu Y

May 28th, 2022 - An 83-year-old man with history of multiple myeloma obtained an FDG PET/CT for surveillance. Although there was no evidence of metabolically active myeloma, an incidental highly FDG-avid focus was noted at the gastroesophageal junction. Findings were interpreted as malignancy. The patient underwent esophagogastroduodenoscopy, which showed nonerythematous desquamation of the distal esophagus con...

68Ga-FAPI-04 PET/CT in Epithelioid Hemangioendothelioma With Pleura and Bone Metastases.
https://doi.org/10.1097/RLU.0000000000004284
Clinical Nuclear Medicine; Chen J, Li C et. al.

May 28th, 2022 - Epithelioid hemangioendothelioma is a low- to intermediate-grade malignant vascular tumor with a slowly progressive course and unpredictable prognosis. We report a case of epithelioid hemangioendothelioma with pleura and bone metastases on 68Ga-FAPI-04 PET/CT in a 65-year-old woman who underwent surgery and chemotherapy.

The utility of neutrophil-to-lymphocyte ratio determined at initial diagnosis in predic...
https://doi.org/10.1080/00325481.2022.2082805
Postgraduate Medicine; Alparslan Bekir S, Sonkaya E et. al.

May 28th, 2022 - To evaluate the utility of neutrophil-lymphocyte ratio (NLR) determined at initial diagnosis in predicting advanced disease stage and discriminating between active and stable disease in sarcoidosis. A total of 465 patients with biopsy-proven sarcoidosis (age: 47 years, 70.5% females) were included in this retrospective cross-sectional study. Data on patient demographics, sarcoidosis stage, clin...

Light-intensity and moderate-to-vigorous intensity physical activity among older adult ...
https://doi.org/10.1002/cam4.4841
Cancer Medicine; Gordon BR, Caru M et. al.

May 28th, 2022 - With an aging population, rising incidence of breast cancer, improved survival rates, and obesity epidemic, there will be a growing population of older adult breast cancer survivors with obesity. This complex population, often with multimorbidity, is at risk for several poor health outcomes, including recurrence, cardiovascular disease, dementia, and diabetes, and a number of deleterious sympto...

Controlled repositioning and primary osteoplasty as a treatment option for the manageme...
https://doi.org/10.1097/BPB.0000000000000930
Journal of Pediatric Orthopedics. Part B; Venkatadass K, Prasad VD et. al.

May 28th, 2022 - The ideal management of an unstable slipped capital femoral epiphysis (SCFE) is still controversial. The currently available options are in-situ screw fixation with delayed corrective osteotomy, closed reduction and screw fixation and anatomic reduction by modified Dunn's procedure (MDP). We present the results of our technique of controlled re-positioning (CRP) with primary osteoplasty in whic...

Idiopathic intracranial hypertension: evaluation of births and fertility through the ho...
https://doi.org/10.1111/1471-0528.17241
BJOG : an International Journal of Obstetrics and Gynaeco... Thaller M, Mytton J et. al.

May 28th, 2022 - Idiopathic intracranial hypertension (IIH) predominantly affects women of reproductive age with obesity and women have a distinct profile of hyperandrogenism and insulin resistance. Polycystic ovary syndrome (PCOS) has an established adverse fertility phenotype that typically affects obese women. As IIH may impact reproductive health, we sought to evaluate fertility, gestational complications, ...

Lithium Pharmacokinetics in the Perinatal Patient with Bipolar Disorder.
https://doi.org/10.1002/jcph.2089
Journal of Clinical Pharmacology; Clark CT, Newmark RL et. al.

May 28th, 2022 - Pharmacokinetics of lithium, the gold standard for the treatment of bipolar disorder, are well described in nonpregnant patients. Because lithium is commonly prescribed to women of childbearing age, more data is essential to characterize lithium pharmacokinetics during the perinatal period. Lithium is primarily eliminated by the kidney. As a result, shifts in lithium elimination clearance paral...

Pre-pregnancy exposure to arsenic in diet and non-cardiac birth defects.
https://doi.org/10.1017/S1368980022001318
Public Health Nutrition; Suhl J, Conway KM et. al.

May 28th, 2022 - To explore associations between maternal pre-pregnancy exposure to arsenic in diet and non-cardiac birth defects. Population-based, case-control study using maternal responses to a dietary assessment and published arsenic concentration estimates in food items to calculate average daily total and inorganic arsenic exposure during the year before pregnancy. Assigning tertiles of total and inorgan...

Breathing in Duchenne muscular dystrophy: Translation to therapy.
https://doi.org/10.1113/JP281671
The Journal of Physiology; Mhandire DZ, Burns DP et. al.

May 28th, 2022 - Duchenne muscular dystrophy (DMD) is an X-linked neuromuscular disease caused by a deficiency in dystrophin - a structural protein which stabilizes muscle during contraction. Dystrophin deficiency adversely affects the respiratory system leading to sleep-disordered breathing, hypoventilation, and weakness of the expiratory and inspiratory musculature, which culminate in severe respiratory dysfu...

A comparison of country-level data from the VISIONARY study examining treatment outcome...
https://doi.org/10.1080/03007995.2022.2083324
Current Medical Research and Opinion; Holló G, Kirwan J et. al.

May 28th, 2022 - Analysis and comparison of country-level data from the VISIONARY study, examining treatment outcomes with the topical fixed-dose combination of preservative-free tafluprost (0.0015%) and timolol (0.5%) (PF tafluprost/timolol FC) in adults with open-angle glaucoma (OAG) and ocular hypertension (OHT) who were insufficiently treated with or unable to tolerate either beta-blocker or prostaglandin a...

Severe hypocalcemia mimicking acute ST-segment elevation myocardial infarction: Paradig...
https://doi.org/10.5603/CJ.a2022.0048
Cardiology Journal; Peiro B, Cerdán L et. al.

May 28th, 2022 - Severe hypocalcemia mimicking acute ST-segment elevation myocardial infarction: Paradigmatic case and review of literature.|2022|Peiro B,Cerdán L,Diarte JA,Ortas MR,Cortés C,|

Supportive management of patients with pheochromocytoma/paraganglioma undergoing noninv...
https://doi.org/10.1097/MED.0000000000000724
Current Opinion in Endocrinology, Diabetes, and Obesity; Talvacchio S, Nazari MA et. al.

May 28th, 2022 - Many publications review perioperative management of pheochromocytomas/paragangliomas (PPGLs); however, a large population, including 10-20% of metastatic PPGL patients, have inoperable disease. This has necessitated the development of noninvasive treatments (e.g., radio/chemotherapy), which, in affording disease-modification, have led to an ever-growing population of surviving patients with in...