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About 1,893,880 results

Optical biopsy for esophageal squamous cell neoplasia by using endocytoscopy.
https://doi.org/10.1186/s12876-022-02335-5 10.1111/jgh.12477 10.1038/ajg.2014.94 10.1055/s-0035-1569644 10.1055/s-2006-944667 10.1111/j.1442-2050.2011.01241.x 10.1136/gut.47.2.251 10.1007/s10388-016-0551-7 10.1136/gut.51.1.130 10.1016/j.gie.2005.09.027 10.1055/s-0032-1325932 10.1111/den.12601 10.1055/a-1068-9228 10.1053/j.gastro.2016.07.040 10.1038/s41598-020-76309-6 10.1159/000506930 10.21037/tgh.2019.11.12 10.1002/1097-0142(19950915)76:6<928::AID-CNCR2820760604>3.0.CO;2-5 10.1186/1471-230X-14-141 10.1111/j.1440-1746.2009.06032.x 10.1097/CM9.0000000000000623 10.1016/j.gie.2018.07.037 10.1016/j.gie.2018.11.011 10.1053/j.gastro.2018.06.037 10.1053/j.gastro.2016.04.004 10.1055/s-0042-113609 10.1007/s10388-018-0651-7
BMC Gastroenterology; Shimoda Y, Shimizu Y et. al.

May 22nd, 2022 - Endocytoscopy (ECS) enables microscopic observation in vivo for the gastrointestinal mucosa; however, there has been no prospective study in which the diagnostic accuracy of ECS for lesions that have not yet undergone histological diagnosis was evaluated. We conducted a surveillance study for patients in a high-risk group of esophageal squamous cell carcinoma (ESCC) and evaluated the in vivo hi...

Atraumatic splenic rupture in a child with COVID 19.
https://doi.org/10.1186/s12887-022-03353-8 10.1016/j.biopha.2020.110195 10.3201/eid2608.201161 10.1016/j.clinpr.2020.100042 10.1186/s12893-020-00887-5 10.1016/S0025-6196(12)60835-0 10.1016/j.epsc.2020.101680 10.12659/AJCR.893919 10.1542/peds.2006-3071 10.1002/bjs.6737 10.1016/j.ijid.2013.10.022 10.1155/2021/5553619 10.1186/1752-1947-8-396 10.1002/path.1560 10.3760/cma.j.cn112151-2020041-00278 10.12659/AJCR.883739 10.1136/bmj.m1985 10.1001/jama.2020.10369 10.1093/jscr/rjaa337 10.1136/bmj.g1864 10.1007/s10353-018-0545-x 10.1016/j.injury.2006.07.018
BMC Pediatrics; Bakalli I, Biqiku M et. al.

May 22nd, 2022 - The majority of children with COVID-19 have only minor symptoms or none at all. COVID-19, on the other hand, can cause serious illness in some children, necessitating hospitalization, intensive care, and invasive ventilation. Many studies have revealed that SARS-CoV-2 affects not only the respiratory system, but also other vital organs in the body. We report here a child with an atraumatic sple...

Needle tract seeding and abdominal recurrence following pre-treatment biopsy of gastroi...
https://doi.org/10.1186/s12893-022-01648-2 10.1186/s12889-018-5131-4 10.1016/j.canep.2015.10.031 10.1016/S0016-5085(98)70079-4 10.1016/j.humpath.2017.01.005 10.1056/NEJMoa020461 10.1056/NEJM200104053441404 10.1177/1758835920936932 10.1093/annonc/mdy096 10.1186/s13569-017-0072-8 10.1159/000493405 10.1038/bjc.2017.144 10.1245/s10434-013-3013-7 10.1016/j.ejso.2018.01.087 10.1002/jso.26494 10.1159/000494303 10.1148/rg.336135507 10.3748/wjg.v23.i14.2493 10.1007/s00261-016-0945-y 10.1016/j.annonc.2020.03.304 10.1002/jso.26215 10.1001/archsurg.1992.01420100114020 10.1684/ejd.2013.2249 10.1016/S0168-8278(05)80269-7 10.3748/wjg.v13.i14.2077 10.1067/mge.2002.120323 10.3109/00365521.2013.845796 10.1002/cncr.20360 10.1007/s00464-018-6564-7 10.1002/jso.21120 10.1016/j.urolonc.2005.02.001 10.1159/000370057 10.1016/j.athoracsur.2007.05.071 10.1590/S0102-86502012000500007 10.1245/s10434-018-6353-5 10.1016/S1499-3872(11)60056-8 10.1097/DCR.0000000000001376 10.1007/s00595-012-0134-8 10.1097/MD.0000000000019885 10.1007/s00508-014-0660-z 10.1097/MD.0000000000012816 10.3748/wjg.v27.i13.1354 10.1016/j.ejca.2016.02.021 10.15403/jgld.2014.1121.234.eug 10.1001/jamasurg.2020.0397 10.1093/annonc/mdz124 10.1093/annonc/mdx484 10.1136/gut.2008.149062 10.1007/s00268-009-0362-2 10.1111/bju.12849 10.1016/j.ejso.2017.06.009 10.1002/cncy.22147 10.1038/ajg.2009.132 10.1200/jco.2012.30.15_suppl.10031 10.1186/1471-2407-11-72 10.1002/jso.21160
BMC Surgery; Jakob J, Salameh R et. al.

May 22nd, 2022 - Gastrointestinal stromal tumors (GIST) are rare abdominal tumors. Pretreatment biopsies may be used to diagnose a GIST and enable tailored treatment. Some experts are skeptical about biopsies because they fear tumor cell seeding. The objective of this study was to determine if pretreatment biopsy is associated with increased tumor recurrence. We performed a systematic literature search and incl...

Factors of family impact in a Swedish-German cohort of children born with esophageal at...
https://doi.org/10.1186/s13023-022-02361-2 10.1136/archdischild-2011-300597 10.1038/s41572-019-0077-0 10.1055/s-0040-1710389 10.1007/s00431-016-2760-4 10.1136/archdischild-2017-314710 10.1097/MPG.0000000000002468 10.1055/s-0040-1716880 10.1002/ppul.24982 10.1186/s13023-021-02153-0 10.1097/MPG.0000000000001401 10.1055/s-0040-1713596 10.1111/j.1469-7610.2007.01727.x 10.1093/jpepsy/jsy075 10.1093/jpepsy/jsz024 10.1007/s10826-017-0831-4 10.1186/s12875-016-0488-x 10.1007/s10826-013-9864-5 10.1371/journal.pone.0150760 10.1002/ajmg.a.33605 10.1016/j.jpedsurg.2013.11.068 10.1016/j.pedn.2021.02.016 10.1055/s-0038-1660867 10.1016/j.pedn.2019.04.009 10.1016/S0022-3468(99)90485-2 10.1016/j.jpedsurg.2008.09.027 10.1097/MPG.0000000000002019 10.1586/14737167.5.6.705 10.1186/1477-7525-2-55 10.1097/00005650-200108000-00006 10.1007/s00431-013-2049-9 10.1186/s12887-019-1701-6 10.1186/s13023-021-01748-x 10.1097/MPG.0000000000001797 10.1016/j.jpedsurg.2017.11.057 10.1016/0022-3468(92)90575-R 10.1007/s11136-019-02364-w 10.1186/s13023-021-01828-y 10.1007/s11136-008-9350-5 10.1016/j.jpedsurg.2017.05.033 10.1111/dote.12062 10.1016/j.jpedsurg.2008.04.011 10.1186/s13023-021-01998-9 10.1186/s13023-021-02127-2 10.3389/fped.2020.00364 10.1016/j.jpedsurg.2020.12.0241 10.1007/s10826-017-0800-y
Orphanet Journal of Rare Diseases; Dellenmark-Blom M, Abrahamsson K et. al.

May 22nd, 2022 - After repair of esophageal atresia (EA), childhood survivors commonly present with digestive and respiratory morbidity, and around 55% have associated anomalies. Although it is known that these problems can reduce health-related quality of life in children with EA, less is understood about the impact on the family. We aimed to identify factors related to family impact in children with EA. One p...

Transition to adult care of young patients with neurofibromatosis type 1 and cognitive ...
https://doi.org/10.1186/s13023-022-02356-z 10.1038/nrdp.2017.4 10.1002/ajmg.a.38680 10.1111/dmcn.13526 10.1002/ajmg.a.61627 10.1017/S0012162201001876 10.1542/peds.2013-1868 10.1016/j.yebeh.2019.04.027 10.1097/MOP.0b013e328305e128 10.1542/peds.2004-1321 10.1136/adc.2010.202473 10.1002/ajmg.a.35982 10.1001/jamapediatrics.2015.3168 10.1002/ajmg.a.35840 10.1016/j.jbi.2008.08.010 10.1016/j.jadohealth.2012.12.014 10.1080/13651501.2021.1895524
Orphanet Journal of Rare Diseases; Lausdahl S, Handrup MM et. al.

May 22nd, 2022 - The transition of adolescents to adult care is known to be challenging. Studies indicate that patients with a chronic disease and cognitive deficits are at risk of inadequate transition to adult care, which eventually may result in disease deterioration. This study investigated the transition process for patients with neurofibromatosis type 1 (NF1) and discussed whether patients with NF1 and co...

Papillary muscle avulsion following balloon mitral valvotomy evaluated with three-dimen...
https://doi.org/10.1186/s12893-022-01636-6 10.1002/ccd.21008 10.1186/1476-7120-5-48 10.1136/hrt.60.4.299 10.1017/S1047951114001942 10.1016/S0003-4975(00)02498-X 10.1016/j.jtcvs.2019.02.120
BMC Surgery; Bai W, Deng L et. al.

May 22nd, 2022 - Percutaneous balloon mitral valvotomy is a common therapeutic approach for rheumatic mitral stenosis. Avulsion of the papillary muscle is a rare but serious complication of balloon mitral valvotomy. The papillary muscles are derived from the trabecular layer of the developing ventricular walls. When subjected to a force, avulsion of papillary muscle from the trabecular layer may occur. In this ...

Long-term evaluation of the safety and efficacy of recombinant human pentraxin-2 (rhPTX...
https://doi.org/10.1186/s12931-022-02047-0 10.1164/rccm.201807-1255ST 10.1183/16000617.0062-2017 10.1186/s12931-019-1020-3 10.1136/bmjresp-2018-000397 10.1183/13993003.02279-2019 10.1056/NEJMoa1402582 10.1056/NEJMoa1402584 10.1001/jama.2018.6129 10.1183/13993003.01209-2017 10.1016/S2213-2600(19)30172-9 10.1164/rccm.2009-040GL 10.1126/scitranslmed.3000111 10.1016/j.jaci.2010.06.010 10.1016/j.biocel.2010.10.013 10.1172/jci.insight.87446 10.1084/jem.20160283 10.1183/13993003.00850-2015 10.1159/000479976
Respiratory Research; Raghu G, Hamblin MJ et. al.

May 22nd, 2022 - Recombinant human pentraxin-2 (rhPTX-2) significantly decreased decline in percent predicted forced vital capacity (FVC) and stabilized 6-min walk distance (6MWD) in patients with idiopathic pulmonary fibrosis (IPF) during the 28-week, placebo-controlled, randomized period of the Phase II PRM-151-202 study. Interim (76-week) data from the open-label extension (OLE) demonstrated sustained safety...

The prevalence of musculoskeletal pain and therapy needs in adults with Osteogenesis Im...
https://doi.org/10.1186/s12891-022-05433-3 10.2147/JMDH.S113483 10.1002/ajmg.a.36545 10.1016/j.jpain.2003.12.005 10.1093/fampra/cmx034 10.1016/j.jbspin.2019.02.001 10.1016/j.neubiorev.2021.02.009 10.1007/s00198-005-1905-5 10.1007/s11136-016-1247-0 10.1136/bjsports-2018-099198
BMC Musculoskeletal Disorders; Barlow S, Dove L et. al.

May 22nd, 2022 - Osteogenesis Imperfecta affects approximately 1 in every 10,000 people. Musculoskeletal disorders and pain are common in adults with Osteogenesis Imperfecta, but specific knowledge of the problems people have is lacking. Access to therapy services for adults with Osteogenesis Imperfecta is variable. We designed this analysis to better understand the musculoskeletal disorders and consequent ther...

Cyclic thrombocytopenia related to erythropoietin-dependent anti-platelet anti-GPIV/III...
https://doi.org/10.1007/s40620-022-01348-3 10.1016/j.bcp.2011.06.045 10.1056/NEJM199603073341004 10.1056/NEJMoa011931 10.1182/blood.V95.9.2983.009k27_2983_2989 10.7326/0003-4819-111-12-992 10.1182/blood.V80.2.352.352 10.1016/j.intimp.2011.10.014 10.1056/NEJMra066469 10.1016/S0008-6363(03)00468-1 10.1186/1477-9560-12-18 10.1111/bcp.12835 10.1053/j.ajkd.2016.12.011 10.1054/bjoc.2001.1746
Journal of Nephrology; Florens N, Bordet JC et. al.

May 22nd, 2022 - We describe herein the case of a 65-year-old patient on chronic hemodialysis with a medical history of idiopathic thrombocytopenia who experienced numerous episodes of severe thrombocytopenia with no specific diagnosis. Further analysis of the evolution of the platelet count showed that cyclic thrombocytopenia occurred after each injection of recombinant erythropoietin (rHu-EPO). Exploration of...

BTK Inhibitors and CAR T-Cell Therapy in Treating Mantle Cell Lymphoma-Finding a Dancin...
https://doi.org/10.1007/s11912-022-01286-0 10.1038/s41375-020-01072-6 10.1182/blood-2015-03-635326 10.1038/s41375-018-0023-2 10.1186/s13045-021-01049-7 10.1182/bloodadvances.2018013060 10.1182/blood-2013-06-507947 10.1186/s13045-016-0250-9 10.1021/acs.jmedchem.9b00687 10.1016/S0140-6736(17)33108-2 10.1056/NEJMoa1914347 10.1111/bjh.15567 10.3389/fonc.2020.591577 10.1097/MOH.0000000000000548 10.1002/ijc.33212 10.1182/blood-2015-11-679134 10.1111/cas.14915 10.1182/blood.2019002936 10.1182/bloodadvances.2020003391 10.1097/CJI.0000000000000307 10.1186/s13045-020-00914-1 10.1016/S0140-6736(15)00667-4 10.1182/blood-2020-134824 10.1016/S0140-6736(21)00224-5 10.1182/blood-2015-05-647834 10.3389/fonc.2021.760405 10.3389/fcell.2021.630942 10.3389/fonc.2021.668162 10.1182/blood.2020006449 10.1111/jth.13651 10.1038/leu.2014.247 10.1200/JCO.21.00693 10.1016/j.jacc.2019.07.056 10.1111/bjh.14870 10.21037/apm.2019.08.05 10.1182/blood.2020006844 10.1016/j.ccell.2017.04.012 10.1182/blood-2017-11-818286 10.1182/blood-2019-125488 10.1182/blood-2019-127674 10.1038/s41467-021-22872-z 10.3389/fimmu.2021.689472 10.1038/s41419-017-0157-6 10.1002/ajh.25418 10.3389/fonc.2020.00849 10.1016/j.bbmt.2019.08.015 10.1182/blood-2020-136158 10.1182/blood-2021-153277 10.1182/blood-2021-148626 10.1200/JCO.2017.72.8519 10.1182/blood-2020-136831 10.1182/blood-2021-146941 10.1016/j.bbmt.2018.12.758 10.1136/esmoopen-2020-000746 10.1038/s41571-019-0297-y 10.1182/blood-2021-150431 10.1182/blood-2021-150592 10.1158/2159-8290.CD-18-0442 10.3324/haematol.2020.267914 10.1182/blood-2021-151073 10.1007/s11864-021-00907-3 10.3324/haematol.2018.198812 10.1186/s13045-021-01188-x 10.1016/j.leukres.2020.106432 10.1111/imcb.12254
Current Oncology Reports; Munoz JL, Wang Y et. al.

May 22nd, 2022 - This review focuses on the feasibility of combining Bruton's tyrosine kinase (BTK) inhibitors (BTKis) with chimeric antigen receptor (CAR) T-cell therapy in patients with relapsed or refractory (R/R) mantle cell lymphoma (MCL). Potential scenarios for combination treatment with these agents are presented. BTKis and CAR T-cell therapy have revolutionized the treatment paradigm for R/R MCL. Ibrut...

Progressive cholestasis and associated sclerosing cholangitis are frequent complication...
https://doi.org/10.1002/hep.32582
Hepatology (Baltimore, Md.); Hartl L, Haslinger K et. al.

May 22nd, 2022 - Cholestasis is associated with disease severity and worse outcome in coronavirus disease of 2019 (COVID-19). Cases of secondary sclerosing cholangitis (SSC) after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection have been described. Hospitalized patients with COVID-19 between 03/2020 and 07/2021 were included. Patients were stratified as having (i) no chronic liver disease...

Quaternary Nanoparticles Enable Sustained Release of Bortezomib for Hepatocellular Carc...
https://doi.org/10.1002/hep.32584
Hepatology (Baltimore, Md.); Li L, Zhang Y et. al.

May 22nd, 2022 - Hepatocellular carcinoma (HCC) represents the 3rd leading cause of cancer-related mortality in the world. Over the past 2 decades, there has been minimal improvement in therapies as well as clinical outcomes for Barcelona Clinic Liver Cancer (BCLC)-B patients. These patients are treated with local interventions, including trans-arterial chemoembolization (TACE). Current methodologies only allow...

Effectiveness of BNT162b2 and ChAdOx-1 vaccines in residents of long-term care faciliti...
https://doi.org/10.1093/ageing/afac115
Age and Ageing; Paranthaman K, Subbarao S et. al.

May 22nd, 2022 - residents of long-term care facilities (LTCFs) are at high risk of adverse outcomes from SARS-CoV-2. We aimed to estimate the vaccine effectiveness (VE) of one and two doses of BNT162b2 and ChAdOx-1 against SARS CoV-2 infection and COVID-19-related death in residents of LTCFs. this observational study used testing, vaccination and mortality data for LTCF residents aged ≥ 65 years who were regul...

Replicating and redesigning ankle-foot orthoses with 3D printing for children with Char...
https://doi.org/10.1016/j.gaitpost.2022.05.006
Gait & Posture; Wojciechowski EA, Cheng TL et. al.

May 22nd, 2022 - Children with the most common inherited neuropathy, Charcot-Marie-Tooth disease (CMT), are often prescribed ankle-foot orthoses (AFOs) to improve walking ability and prevent falls by reducing foot drop, postural instability, and other gait impairments. These externally worn assistive devices are traditionally custom-made using thermoplastic vacuum forming. This labour-intensive manufacturing pr...

Clinical features and outcomes of leucine-rich glioma-inactivated protein 1 and contact...
https://doi.org/10.1016/j.jocn.2022.05.007
Journal of Clinical Neuroscience : Official Journal of Th... Li HY, Qiao S et. al.

May 22nd, 2022 - The present study aimed to investigate the clinical manifestations, epidemiological characteristics, and outcomes of Chinese patients with voltage-gated potassium channel complex (VGKC) antibody-associated encephalitis. Patients diagnosed with VGKC antibody-associated encephalitis at our institution between January 2016 and December 2020 were included in this study. We retrospectively evaluated...

ONSET OF MULTIPLE SCLEROSIS IS PREVENTABLE - TIME TO ACT NOW!
https://doi.org/10.1016/j.msard.2022.103875
Multiple Sclerosis and Related Disorders; Hawkes CH, Giovannoni G et. al.

May 22nd, 2022 - ONSET OF MULTIPLE SCLEROSIS IS PREVENTABLE - TIME TO ACT NOW!|2022|Hawkes CH,Giovannoni G,Lechner-Scott J,Levy M,Yeh A,|

Effects of disease-modifying treatments discontinuation in patients with relapsing-remi...
https://doi.org/10.1016/j.msard.2022.103857
Multiple Sclerosis and Related Disorders; Bawand R, Ghiasian M et. al.

May 22nd, 2022 - One of the most challenging issues in patients with multiple sclerosis is the discontinuation of Disease-Modifying Treatments (DMTs) and subsequent complications. We aimed to investigate the extent of adherence to DMTs in naïve multiple sclerosis patients, outcomes of non-adherence to treatments, and the risk factors that lead to drug discontinuation. In this prospective cohort study, 288 naïve...

Feedback from neurology residents and neuroimmunology fellows about the practical train...
https://doi.org/10.1016/j.msard.2022.103821
Multiple Sclerosis and Related Disorders; Diogo Silva G

May 22nd, 2022 - To obtain feedback from Neurology residents and Neuroimmunology fellows about the practical training in multiple sclerosis (MS). A survey was developed and administered electronically to Neurology residents or Neuroimmunology fellows that received training in eight large MS outpatient clinics in Brazil, from 2018 to 2021. We evaluated their beliefs on: (1) the optimal number of MS patients eval...

Defining milestones for the study of remyelination using the cuprizone mouse model: How...
https://doi.org/10.1016/j.msard.2022.103886
Multiple Sclerosis and Related Disorders; Palavra F, Viana SD et. al.

May 22nd, 2022 - Cuprizone (CPZ) is a copper chelator used to produce a reversible oligodendrocytopathy in animals, which has some similarities to the pathology found in human multiple sclerosis (MS). This model is attractive to study remyelination. To demonstrate that a two-week period after cessation of CPZ exposure is sufficient to establish changes compatible with remyelination, without accompanying behavio...

Home treatment against fatigue in multiple sclerosis by a personalized, bilateral whole...
https://doi.org/10.1016/j.msard.2022.103813
Multiple Sclerosis and Related Disorders; Tecchio F, Cancelli A et. al.

May 22nd, 2022 - Fatigue in multiple sclerosis (MS) is a highly invalidating symptom with no pharmacological efficacious therapies, which furthermore present frequent severe side effects. In two previous randomized controlled trials we observed the efficacy of a personalized neuromodulation treatment consisting of a personalized transcranial Direct Current Stimulation (tDCS) for 15 min per day for 5 days (Farem...