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About 342,894 results

Lessons From Continuous Glucose Monitoring in Youth With Pre–Type 1 Diabetes, Obesity, and Cystic Fibrosis
https://care.diabetesjournals.org/content/diacare/early/2020/01/13/dc19-1690.full.pdf

Glucose abnormalities exist in the prediabetic state well before a diagnosis of diabetes is made, and continuous glucose monitoring (CGM) is a sensitive method to detect these early abnormalities. Although insufficient data exist to support CGM for diagnosing diabetes, glucose patterns on CGM can provide insight into disease pathophysiology. Our group has used CGM to study early dysglyce...

Management of Infants Born to Mothers with COVID-19
https://downloads.aap.org/AAP/PDF/COVID 19 Initial Newborn Guidance.pdf

IVF Transfer of Fresh or Frozen Embryos in Women without Polycystic Ovaries.
https://doi.org/10.1056/NEJMoa1703768
The New England Journal of Medicine; Vuong LN, Dang VQ et. al.

Jan 10th, 2018 - Among women who are undergoing in vitro fertilization (IVF), the transfer of frozen embryos has been shown to result in a higher rate of live birth than the transfer of fresh embryos in those with infertility associated with the polycystic ovary syndrome. It is not known whether frozen-embryo transfer results in similar benefit in women with infertility that is not associated with the polycysti...

Birth Outcomes for Pregnant Women with HIV Using Tenofovir-Emtricitabine.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984044
The New England Journal of Medicine; Rough K, Seage GR et. al.

Apr 25th, 2018 - In a previous trial of antiretroviral therapy (ART) involving pregnant women with human immunodeficiency virus (HIV) infection, those randomly assigned to receive tenofovir, emtricitabine, and ritonavir-boosted lopinavir (TDF-FTC-LPV/r) had infants at greater risk for very premature birth and death within 14 days after delivery than those assigned to receive zidovudine, lamivudine, and ritonavi...

Cystic Fibrosis Colorectal Cancer Screening Consensus Recommendations.
https://doi.org/10.1053/j.gastro.2017.12.012
Gastroenterology Hadjiliadis D, Khoruts A et. al.

Dec 31st, 2017 - Improved therapy has substantially increased survival of persons with cystic fibrosis (CF). But the risk of colorectal cancer (CRC) in adults with CF is 5-10 times greater compared to the general population, and 25-30 times greater in CF patients after an organ transplantation. To address this risk, the CF Foundation convened a multi-stakeholder task force to develop CRC screening recommendatio...

Labor Induction versus Expectant Management in Low-Risk Nulliparous Women.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186292
The New England Journal of Medicine; Grobman WA, Rice MM et. al.

Aug 8th, 2018 - The perinatal and maternal consequences of induction of labor at 39 weeks among low-risk nulliparous women are uncertain. In this multicenter trial, we randomly assigned low-risk nulliparous women who were at 38 weeks 0 days to 38 weeks 6 days of gestation to labor induction at 39 weeks 0 days to 39 weeks 4 days or to expectant management. The primary outcome was a composite of perinatal death ...

Time to Epinephrine Administration and Survival From Nonshockable Out-of-Hospital Cardi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940513
Circulation Hansen M, Schmicker RH et. al.

Mar 7th, 2018 - Previous studies have demonstrated that earlier epinephrine administration is associated with improved survival from out-of-hospital cardiac arrest (OHCA) with shockable initial rhythms. However, the effect of epinephrine timing on patients with nonshockable initial rhythms is unclear. The objective of this study was to measure the association between time to epinephrine administration and surv...

Identification of Extremely Premature Infants at Low Risk for Early-Onset Sepsis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654397
Pediatrics Puopolo KM, Mukhopadhyay S et. al.

Oct 6th, 2017 - Premature infants are at high risk of early-onset sepsis (EOS) relative to term infants, and most are administered empirical antibiotics after birth. We aimed to determine if factors evident at birth could be used to identify premature infants at lower risk of EOS. Study infants were born at 22 to 28 weeks' gestation in Neonatal Research Network centers from 2006 to 2014. EOS was defined by iso...

Pregnancy outcome following in utero exposure to lithium: a prospective, comparative, o...
https://doi.org/10.1176/appi.ajp.2014.12111402
The American Journal of Psychiatry; Diav-Citrin O, Shechtman S et. al.

May 1st, 2014 - The authors conducted a prospective, comparative observational study to evaluate the risk of major anomalies following exposure to lithium during pregnancy. A total of 183 lithium-exposed pregnancies of women who contacted the Israeli Teratology Information Service were followed up (90.2% in the first trimester) and compared with 72 disease-matched and 748 nonteratogenic-exposed pregnancies. Th...

Prevention of dental caries in children from birth through age 5 years: US Preventive S...
https://doi.org/10.1542/peds.2014-0483
Pediatrics Moyer VA,

May 6th, 2014 - Update of the 2004 US Preventive Services Task Force (USPSTF) recommendation on prevention of dental caries in preschool-aged children. The USPSTF reviewed the evidence on prevention of dental caries by primary care clinicians in children 5 years and younger, focusing on screening for caries, assessment of risk for future caries, and the effectiveness of various interventions that have possible...

Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368900
JAMA Dabelea D, Mayer-Davis EJ et. al.

May 5th, 2014 - Despite concern about an "epidemic," there are limited data on trends in prevalence of either type 1 or type 2 diabetes across US race and ethnic groups. To estimate changes in the prevalence of type 1 and type 2 diabetes in US youth, by sex, age, and race/ethnicity between 2001 and 2009. Case patients were ascertained in 4 geographic areas and 1 managed health care plan. The study population w...

Circumcision rates in the United States: rising or falling? What effect might the new a...
https://doi.org/10.1016/j.mayocp.2014.01.001
Mayo Clinic Proceedings; Morris BJ, Bailis SA et. al.

Apr 7th, 2014 - The objective of this review was to assess the trend in the US male circumcision rate and the impact that the affirmative 2012 American Academy of Pediatrics policy statement might have on neonatal circumcision practice. We searched PubMed for the term circumcision to retrieve relevant articles. This review was prompted by a recent report by the Centers for Disease Control and Prevention that f...

Effect of smoke-free legislation on perinatal and child health: a systematic review and...
https://doi.org/10.1016/S0140-6736(14)60082-9
Lancet (London, England); Been JV, Nurmatov UB et. al.

Mar 31st, 2014 - Smoke-free legislation has the potential to reduce the substantive disease burden associated with second-hand smoke exposure, particularly in children. We investigated the effect of smoke-free legislation on perinatal and child health. We searched 14 online databases from January, 1975 to May, 2013, with no language restrictions, for published studies, and the WHO International Clinical Trials ...

A genetic basis for infectious mononucleosis: evidence from a family study of hospitali...
https://doi.org/10.1093/cid/ciu204
Clinical Infectious Diseases : an Official Publication Of... Rostgaard K, Wohlfahrt J et. al.

Apr 3rd, 2014 - Circumstantial evidence from genome-wide association and family studies of various Epstein-Barr virus-associated diseases suggests a substantial genetic component in infectious mononucleosis (IM) etiology. However, familial aggregation of IM has scarcely been studied. We used data from the Danish Civil Registration System and the Danish National Hospital Discharge Register to study rate ratios ...

Prevention of vertical transmission of hepatitis B: an observational study.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086733
Annals of Internal Medicine; Kubo A, Shlager L et. al.

May 27th, 2014 - For mothers with chronic hepatitis B virus (HBV) infection, the Centers for Disease Control and Prevention recommends immunoprophylaxis to decrease perinatal transmission. However, its effectiveness and risk factors for failure have not been well-studied in community practice. To investigate the effectiveness of a contemporary immunoprophylaxis protocol. Observational study. An HBV perinatal im...

Vitamin C supplementation for pregnant smoking women and pulmonary function in their ne...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296045
JAMA McEvoy CT, Schilling D et. al.

May 19th, 2014 - Maternal smoking during pregnancy adversely affects offspring lung development, with lifelong decreases in pulmonary function and increased asthma risk. In a primate model, vitamin C blocked some of the in-utero effects of nicotine on lung development and offspring pulmonary function. To determine if newborns of pregnant smokers randomized to receive daily vitamin C would have improved results ...

Continuous renal replacement therapy in neonates and small infants: development and fir...
https://doi.org/10.1016/S0140-6736(14)60799-6
Lancet (London, England); Ronco C, Garzotto F et. al.

May 26th, 2014 - Peritoneal dialysis is the renal replacement therapy of choice for acute kidney injury in neonates, but in some cases is not feasible or effective. Continuous renal replacement therapy (CRRT) machines are used off label in infants smaller than 15 kg and are not designed specifically for small infants. We aimed to design and create a CRRT machine specifically for neonates and small infants. We p...

Antidepressant use in pregnancy and the risk of cardiac defects.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062924
The New England Journal of Medicine; Huybrechts KF, Palmsten K et. al.

Jun 18th, 2014 - Whether the use of selective serotonin-reuptake inhibitors (SSRIs) and other antidepressants during pregnancy is associated with an increased risk of congenital cardiac defects is uncertain. In particular, there are concerns about a possible association between paroxetine use and right ventricular outflow tract obstruction and between sertraline use and ventricular septal defects. We performed ...

Effectiveness of maternal pertussis vaccination in England: an observational study.
https://doi.org/10.1016/S0140-6736(14)60686-3
Lancet (London, England); Amirthalingam G, Andrews N et. al.

Jul 19th, 2014 - In October, 2012, a pertussis vaccination programme for pregnant women was introduced in response to an outbreak across England. We aimed to assess the vaccine effectiveness and the overall effect of the vaccine programme in preventing pertussis in infants. We undertook an analysis of laboratory-confirmed cases and hospital admissions for pertussis in infants between Jan 1, 2008, and Sept 30, 2...

Re-evaluation of link between interpregnancy interval and adverse birth outcomes: retro...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137882
BMJ (Clinical Research Ed.); Ball SJ, Pereira G et. al.

Jul 24th, 2014 - To re-evaluate the causal effect of interpregnancy interval on adverse birth outcomes, on the basis that previous studies relying on between mother comparisons may have inadequately adjusted for confounding by maternal risk factors. Retrospective cohort study using conditional logistic regression (matching two intervals per mother so each mother acts as her own control) to model the incidence o...