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Real-time assessment of COVID-19 prevalence among multiple sclerosis patients: a multicenter European study
https://link.springer.com/article/10.1007/s10072-020-04519-x

We assessed the prevalence and impact of COVID-19 among multiple sclerosis (MS) patients across Europe by leveraging participant data collected as part of the ongoing EU IMI2 RADAR-CNS major programme aimed at finding new ways of monitoring neurological disorders using wearable devices and smartphone technology. In the present study, 399 patients of RADAR-MS have been included (mean age 43.9 ye...

We test a home antibody kit for tracking Covid-19
https://www.nature.com/articles/d41586-020-01677-y

Home testing kits will likely be an important part of monitoring Covid-19. Swab tests can tell whether a person is currently infected, while antibody tests look for signs of past infection. But before tests like these are rolled out, researchers need to make sure they're reliable and easy for people to use at home. We gave one of the home testing kits a go, and spoke to researcher Christina Atc...

Assessment of patients who tested positive for COVID-19 after recovery
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30433-3/fulltext

Since the start of the outbreak in December 2019, COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), has led to an increasing number of infections worldwide, with an estimated overall mortality of 5·7%.1 Meanwhile, many patients who were hospitalised have recovered and were discharged to self-quarantine. However, some patients have tested positive for COVID-19 aga...

Mental health and psychosocial considerations during the COVID-19 outbreak
https://apps.who.int/iris/bitstream/handle/10665/331490/WHO-2019-nCoV-MentalHealth-2020.1-eng.pdf

In January 2020 the World Health Organization (WHO) declared the outbreak of a new coronavirus disease, COVID-19, to be a Public Health Emergency of International Concern. WHO stated that there is a high risk of COVID-19 spreading to other countries around the world. In March 2020, WHO made the assessment that COVID-19 can be characterized as a pandemic. WHO and public health authorities ar...

The Covid-19 Pandemic Accelerates the Transition to Virtual Care
https://catalyst.nejm.org/doi/full/10.1056/CAT.20.0399

Kaiser Permanente responded to the Covid-19 pandemic by expanding existing and developing new virtual care modalities. Prior to the pandemic, virtual care consisted primarily of secure e-mail messaging, e-visits, telephone calls, and video visits with the patient’s primary care physician, nurse practitioner, or specialty care physician, all linked to the patient’s electronic medical record. Wit...

ACE2 Expression in Kidney and Testis May Cause Kidney and Testis Damage After 2019-nCoV Infection
https://www.medrxiv.org/content/10.1101/2020.02.12.20022418v1

In December 2019 and January 2020, novel coronavirus (2019-nCoV) - infected pneumonia (NCIP) occurred in Wuhan, and has already posed a serious threat to public health. ACE2 (Angiotensin Converting Enzyme 2) has been shown to be one of the major receptors that mediate the entry of 2019-nCoV into human cells, which also happens in severe acute respiratory syndrome coronavirus (SARS). Several res...

The new International Society of Hypertension guidelines on hypertension
https://journals.lww.com/jhypertension/Fulltext/2020/06000/The_new_International_Society_of_Hypertension.1.aspx?context=LatestArticles
Journal of Hypertension;

The June issue of the Journal of Hypertension starts with the hypertension guidelines prepared by the International Society of Hypertension (ISH) and simultaneously published in Hypertension as well. Compared with the guidelines issued by the European Society of Cardiology (ESC)/European Society of Hypertension (ESH) and American College of Cardiology (ACC)/American Heart Association (AHA) the ...

Prevalence of Dyskinesia and OFF by 30-Minute Intervals Through the Day and Assessment of Daily Episodes of Dyskinesia and OFF: Novel Analyses of Diary Data from Gocovri Pivotal Trials
https://content.iospress.com/articles/journal-of-parkinsons-disease/jpd181565
Journal of Parkinson's Disease;

Jul 29th, 2019 - Evaluate prevalence of troublesome dyskinesia and OFF through the day, assessed by 30-minute intervals, as well as the mean number and duration of troublesome dyskinesia and OFF episodes, transitions between PD states, and effects of Gocovri® (amantadine) extended release capsules on these episodes.

Palliative Care Improves Well-Being and QoL in Phase I Cancer Trial Participants
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200184/full/

May 28th, 2020 - Participants in phase I oncology trials represent a patient population new to palliative care. These patients typically have remarkable symptoms, with a symptom burden comparable to other patients with cancer.1 Thomas J. Smith, MD, FASCO, of Johns Hopkins University, presented the results of a randomized trial evaluating a palliative care intervention (PCI) compared with usual care (UC) for pat...

Assessment of N95 respirator decontamination and re-use for SARS-CoV-2
https://www.medrxiv.org/content/10.1101/2020.04.11.20062018v2.full.pdf

The unprecedented pandemic of SARS-CoV-2 has created worldwide shortages of personal protective equipment, in particular respiratory protection such as N95 respirators. SARS-CoV-2 transmission is frequently occurring in hospital settings, with numerous reported cases of nosocomial transmission highlighting the vulnerability of healthcare workers. In general, N95 respirators are designed for sin...

Vision-based assessment of parkinsonism and levodopa-induced dyskinesia with pose estimation
https://jneuroengrehab.biomedcentral.com/articles/10.1186/s12984-018-0446-z
Journal of NeuroEngineering and Rehabilitation;

Despite the effectiveness of levodopa for treatment of Parkinson’s disease (PD), prolonged usage leads to development of motor complications, most notably levodopa-induced dyskinesia (LID). Persons with PD and their physicians must regularly modify treatment regimens and timing for optimal relief of symptoms. While standardized clinical rating scales exist for assessing the severity of PD sympt...

Assessment of Lupus Anticoagulant Positivity in Patients With Coronavirus Disease 2019 (COVID-19)
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2769229

Quantitative Method for Comparative Assessment of Particle Removal Efficiency of Fabric Masks as Alternatives to Standard Surgical Masks for PPE
https://www.sciencedirect.com/science/article/pii/S2590238520303647

WFH Guidelines for the Management of Hemophilia, 3rd edition
https://onlinelibrary.wiley.com/doi/10.1111/hae.14046
Haemophilia

Aug 2nd, 2020 - This new edition of the World Federation of Hemophilia (WFH) guidelines for the management of hemophilia comes at an exciting time in the evolution of the diagnosis and treatment of this condition. Since the publication of the second edition in 2012, tremendous advances have been made in several aspects of the management of hemophilia. These include genetic assessment as well as therapy with ma...

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans
https://science.sciencemag.org/content/early/2020/08/10/science.abc6261

COVID-19 represents a global crisis, yet major knowledge gaps remain about human immunity to SARS-CoV-2. We analyzed immune responses in 76 COVID-19 patients and 69 healthy individuals from Hong Kong and Atlanta. In PBMCs of COVID-19 patients, there was reduced expression of HLA-DR and pro-inflammatory cytokines by myeloid cells, and impaired mTOR-signaling and IFN-α production by plasmacytoid ...

Association between Hydration Status and Body Composition in Healthy Adolescents from Spain
https://www.mdpi.com/2072-6643/11/11/2692/htm

At present, obesity and overweight are major public health concerns. Their classical determinants do not sufficiently explain the current situation and it is urgent to investigate other possible causes. In recent years, it has been suggested that water intake could have important implications for weight management. Thus, the aim of this study was to examine the effect of hydration status on bod...

Breast Cancer Risk Assessment and Screening in Average-Risk Women
https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2017/07/breast-cancer-risk-assessment-and-screening-in-average-risk-women

Assessment of Relationship of Ketamine Dose With Magnetic Resonance Spectroscopy of Glx and GABA Responses in Adults With Major Depression
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2769233

Detection of Early Disease Risk Factors Associated with Metabolic Syndrome: A New Era with the NMR Metabolomics Assessment
https://www.mdpi.com/2072-6643/12/3/806/htm

Effects of Equal Volume Heavy-Resistance Strength Training Versus Strength Endurance Training on Physical Fitness and Sport-Specific Performance in Young Elite Female Rowers
https://www.frontiersin.org/articles/10.3389/fphys.2020.00888/full

Strength training is an important means for performance development in young rowers. The purpose of this study was to examine the effects of a 9-week equal volume heavy-resistance strength training (HRST) versus strength endurance training (SET) in addition to regular rowing training on primary (e.g., maximal strength/power) and secondary outcomes (e.g., balance) in young rowers. Twenty-six fem...