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About 417,920 results

Genetically Informed Nutrition Guidance
https://www.sciencedirect.com/science/article/pii/B9780128045725000665

Thousands of common genetic variants influence what we should eat and what we actually end up eating. The obvious complexity of these many gene–nutrient interactions should not prevent us from taking a good look at what we already know and asking about the utility of each interaction one by one. For example, we can predict with high sensitivity and specificity whether a particular adult is expr...

Effectiveness of Traditional Strength vs. Power Training on Muscle Strength, Power and Speed with Youth: A Systematic Review and Meta-Analysis
https://www.frontiersin.org/articles/10.3389/fphys.2017.00423/full

Numerous national associations and multiple reviews have documented the safety and efficacy of strength training for children and adolescents. The literature highlights the significant training-induced increases in strength associated with youth strength training. However, the effectiveness of youth strength training programs to improve power measures is not as clear. This discrepancy may be re...

A Copeptin-Based Approach in the Diagnosis of Diabetes Insipidus.
https://doi.org/10.1056/NEJMoa1803760
The New England Journal of Medicine; Fenske W, Refardt J et. al.

Aug 1st, 2018 - The indirect water-deprivation test is the current reference standard for the diagnosis of diabetes insipidus. However, it is technically cumbersome to administer, and the results are often inaccurate. The current study compared the indirect water-deprivation test with direct detection of plasma copeptin, a precursor-derived surrogate of arginine vasopressin. From 2013 to 2017, we recruited 156...

Screening for cognitive impairment in older adults: U.S. Preventive Services Task Force...
https://doi.org/10.7326/M14-0496
Annals of Internal Medicine; Moyer VA,

Mar 25th, 2014 - Update of the 2003 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for dementia. The USPSTF reviewed the evidence on the benefits, harms, and sensitivity and specificity of screening instruments for cognitive impairment in older adults and the benefits and harms of commonly used treatment and management options for older adults with mild cognitive impairment or early de...

The FLUSH study--flush the line and ultrasound the heart: ultrasonographic confirmation...
https://doi.org/10.1016/j.annemergmed.2013.12.020
Annals of Emergency Medicine; Horowitz R, Gossett JG et. al.

Jan 20th, 2014 - Inadvertent arterial placement of a femoral venous catheter may result in serious morbidity, including limb necrosis. The Flush the Line and Ultrasound the Heart (FLUSH) test is visualization of the heart by a subxiphoid ultrasonic view while the central catheter is flushed with agitated saline solution. We wish to determine whether the FLUSH test can verify proper femoral venous line placement...

Accuracy of point-of-care multiorgan ultrasonography for the diagnosis of pulmonary emb...
https://doi.org/10.1378/chest.13-1087
Chest Nazerian P, Vanni S et. al.

Oct 4th, 2013 - Presenting signs and symptoms of pulmonary embolism (PE) are nonspecific, favoring a large use of second-line diagnostic tests such as multidetector CT pulmonary angiography (MCTPA), thus exposing patients to high-dose radiation and to potential serious complications. We investigated the diagnostic performance of multiorgan ultrasonography (lung, heart, and leg vein ultrasonography) and whether...

Geriatric-specific triage criteria are more sensitive than standard adult criteria in i...
https://doi.org/10.1016/j.annemergmed.2014.04.019
Annals of Emergency Medicine; Ichwan B, Darbha S et. al.

Jun 8th, 2014 - We evaluate the sensitivity of Ohio's 2009 emergency medical services (EMS) geriatric trauma triage criteria compared with the previous adult triage criteria in identifying need for trauma center care among older adults. We studied a retrospective cohort of injured patients aged 16 years or older in the 2006 to 2011 Ohio Trauma Registry. Patients aged 70 years or older were considered geriatric...

Diagnostic accuracy of ultrasonography for hand bony fractures in paediatric patients.
https://doi.org/10.1136/archdischild-2013-305678
Archives of Disease in Childhood; Neri E, Barbi E et. al.

Jun 21st, 2014 - Hand fractures are common in childhood, and radiography is the standard diagnostic procedure. US has been used to evaluate bone injuries, mainly in adults for long-bone trauma; there are only a few studies about hand fractures in children. The purpose of this study was to evaluate and confirm the safety and applicability of the US diagnostic procedure in comparison to X-ray diagnosis. This cros...

Abbreviated breast magnetic resonance imaging (MRI): first postcontrast subtracted imag...
https://doi.org/10.1200/JCO.2013.52.5386
Journal of Clinical Oncology : Official Journal of the Am... Kuhl CK, Schrading S et. al.

Jun 24th, 2014 - We investigated whether an abbreviated protocol (AP), consisting of only one pre- and one postcontrast acquisition and their derived images (first postcontrast subtracted [FAST] and maximum-intensity projection [MIP] images), was suitable for breast magnetic resonance imaging (MRI) screening. We conducted a prospective observational reader study in 443 women at mildly to moderately increased ri...

Early lung ultrasonography predicts the occurrence of acute respiratory distress syndro...
https://doi.org/10.1007/s00134-014-3382-9
Intensive Care Medicine; Leblanc D, Bouvet C et. al.

Jul 15th, 2014 - Extent of lung contusion on initial computed tomography (CT) scan predicts the occurrence of acute respiratory distress syndrome (ARDS) in blunt chest trauma patients. We hypothesized that lung ultrasonography (LUS) on admission could also predict subsequent ARDS. Forty-five blunt trauma patients were prospectively studied. Clinical examination, chest radiography, and LUS were performed on arri...

A test for Creutzfeldt-Jakob disease using nasal brushings.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186748
The New England Journal of Medicine; Orrú CD, Bongianni M et. al.

Aug 7th, 2014 - Definite diagnosis of sporadic Creutzfeldt-Jakob disease in living patients remains a challenge. A test that detects the specific marker for Creutzfeldt-Jakob disease, the prion protein (PrP(CJD)), by means of real-time quaking-induced conversion (RT-QuIC) testing of cerebrospinal fluid has a sensitivity of 80 to 90% for the diagnosis of sporadic Creutzfeldt-Jakob disease. We have assessed the ...

Screening for asymptomatic carotid artery stenosis: a systematic review and meta-analys...
https://doi.org/10.7326/M14-0530
Annals of Internal Medicine; Jonas DE, Feltner C et. al.

Jul 8th, 2014 - Approximately 10% of ischemic strokes are caused by carotid artery stenosis (CAS). Estimated prevalence of asymptomatic CAS is 1%. To evaluate evidence on screening and treating asymptomatic adults for CAS. MEDLINE, the Cochrane Library, EMBASE, and trial registries through September 2013; MEDLINE through March 2014 for trials. Good- or fair-quality trials of screening, carotid endarterectomy (...

Galactomannan in bronchoalveolar lavage for diagnosing invasive fungal disease.
https://doi.org/10.1164/rccm.201403-0431OC
American Journal of Respiratory and Critical Care Medicine; Affolter K, Tamm M et. al.

Jul 9th, 2014 - Invasive fungal disease (IFD) is a significant cause of morbidity and mortality in immunocompromised patients. We hypothesize that galactomannan (GM), a component of fungal cell wall, as measured in bronchoalveolar lavage (BAL) might be a diagnostic adjunct in hematologic malignancies. A total of 568 hematologic cases undergoing diagnostic bronchoscopy because of respiratory symptoms and/or sus...

Sensitivity of plain pelvis radiography in children with blunt torso trauma.
https://doi.org/10.1016/j.annemergmed.2014.06.017
Annals of Emergency Medicine; Kwok MY, Yen K et. al.

Aug 4th, 2014 - Plain anteroposterior pelvic radiographs are commonly used to screen children for pelvic fractures or dislocations after blunt torso trauma. The test sensitivity and utility, however, are unclear. We assessed the sensitivity of anteroposterior pelvic radiographs for identifying children with pelvic fractures or dislocations after blunt torso trauma. We hypothesized that anteroposterior pelvic r...

Administration of secretin (RG1068) increases the sensitivity of detection of duct abno...
https://doi.org/10.1053/j.gastro.2014.05.035
Gastroenterology Sherman S, Freeman ML et. al.

Jun 6th, 2014 - Administration of secretin improves noninvasive imaging of the pancreatic duct with magnetic resonance cholangiopancreatography (MRCP). We performed a large prospective study to investigate whether synthetic human secretin (RG1068)-stimulated MRCP detects pancreatic duct abnormalities with higher levels of sensitivity than MRCP. We performed a phase 3, multicenter, baseline-controlled study of ...

Detection of Rickettsia rickettsii, Rickettsia parkeri, and Rickettsia akari in skin bi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568984
Clinical Infectious Diseases : an Official Publication Of... Denison AM, Amin BD et. al.

May 15th, 2014 - Rickettsia rickettsii, Rickettsia parkeri, and Rickettsia akari are the most common causes of spotted fever group rickettsioses indigenous to the United States. Infected patients characteristically present with a maculopapular rash, often accompanied by an inoculation eschar. Skin biopsy specimens are often obtained from these lesions for diagnostic evaluation. However, a species-specific diagn...

Prenatal antidepressant exposure is associated with risk for attention-deficit hyperact...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427538
Molecular Psychiatry; Clements CC, Castro VM et. al.

Aug 26th, 2014 - Previous studies suggested that risk for Autism Spectrum Disorder (ASD) may be increased in children exposed to antidepressants during the prenatal period. The disease specificity of this risk has not been addressed and the possibility of confounding has not been excluded. Children with ASD or attention-deficit hyperactivity disorder (ADHD) delivered in a large New England health-care system we...

CT evaluation of the upper urinary tract in adults younger than 50 years with asymptoma...
https://doi.org/10.2214/AJR.13.11891
AJR. American Journal of Roentgenology; Lisanti CJ, Toffoli TJ et. al.

Aug 25th, 2014 - The purpose of this study is to compare CT urography (CTU) with unenhanced CT in the evaluation of upper urinary tracts in adults younger than 50 years with asymptomatic microscopic hematuria. In this study, 1516 CTU examinations were reviewed in adults younger than 50 years. Inclusion criteria were no significant prior urologic disease and asymptomatic microscopic hematuria with at least one u...

Point-of-care ultrasonography for the diagnosis of acute cardiogenic pulmonary edema in...
https://doi.org/10.1111/acem.12435
Academic Emergency Medicine : Official Journal of the Soc... Al Deeb M, Barbic S et. al.

Sep 1st, 2014 - Acute dyspnea is a common presenting complaint to the emergency department (ED), and point-of-care (POC) lung ultrasound (US) has shown promise as a diagnostic tool in this setting. The primary objective of this systematic review was to determine the sensitivity and specificity of US using B-lines in diagnosing acute cardiogenic pulmonary edema (ACPE) in patients presenting to the ED with acute...

Reflexive culture in adolescents and adults with group A streptococcal pharyngitis.
https://doi.org/10.1093/cid/ciu400
Clinical Infectious Diseases : an Official Publication Of... Dingle TC, Abbott AN et. al.

May 28th, 2014 - Guidelines currently provide conflicting recommendations regarding the diagnosis of group A streptococcal (GAS) pharyngitis in adults. Clinical guidelines state that negative rapid antigen detection tests (RADTs) do not require confirmation by a backup method in adults, whereas laboratory-based guidelines mandate confirmation of a negative RADT in patients of all ages. The objective of this stu...