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About 446,088 results

Long-term bone and lung consequences associated with hospital-acquired severe acute respiratory syndrome: a 15-year follow-up from a prospective cohort study
https://www.nature.com/articles/s41413-020-0084-5

The most severe sequelae after rehabilitation from SARS are femoral head necrosis and pulmonary fibrosis. We performed a 15-year follow-up on the lung and bone conditions of SARS patients. We evaluated the recovery from lung damage and femoral head necrosis in an observational cohort study of SARS patients using pulmonary CT scans, hip joint MRI examinations, pulmonary function tests and hip jo...

Association Between Laparoscopic Antireflux Surgery and Recurrence of Gastroesophageal ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818853
JAMA Maret-Ouda J, Wahlin K et. al.

Sep 12th, 2017 - Cohort studies, mainly based on questionnaires and interviews, have reported high rates of reflux recurrence after antireflux surgery, which may have contributed to a decline in its use. Reflux recurrence after laparoscopic antireflux surgery has not been assessed in a long-term population-based study of unselected patients. To determine the risk of reflux recurrence after laparoscopic antirefl...

Opioid Knowledge and Prescribing Practices Among Obstetrician-Gynecologists.
https://doi.org/10.1097/AOG.0000000000002407
Obstetrics and Gynecology; Madsen AM, Stark LM et. al.

Dec 7th, 2017 - To describe obstetrician-gynecologists' (ob-gyns) knowledge and prescribing practices regarding opioid analgesics. We conducted a cross-sectional survey of a national sample of American College of Obstetricians and Gynecologists Fellows and Junior Fellows who are part of the Collaborative Ambulatory Research Network. We used a sequential mixed-method approach. We collected data on opioid knowle...

Fecal microbiota transplant for relapsing Clostridium difficile infection using a froze...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017893
Clinical Infectious Diseases : an Official Publication Of... Youngster I, Sauk J et. al.

Apr 25th, 2014 - Recurrent Clostridium difficile infection (CDI) with poor response to standard antimicrobial therapy is a growing medical concern. We aimed to investigate the outcomes of fecal microbiota transplant (FMT) for relapsing CDI using a frozen suspension from unrelated donors, comparing colonoscopic and nasogastric tube (NGT) administration. Healthy volunteer donors were screened and a frozen fecal s...

Increased prevalence of celiac disease among pediatric patients with irritable bowel sy...
https://doi.org/10.1001/jamapediatrics.2013.4984
JAMA Pediatrics; Cristofori F, Fontana C et. al.

Apr 23rd, 2014 - Recurrent abdominal pain is a prevalent health issue in childhood. Clinical criteria (ie, the Rome criteria) have been established to aid diagnosis. Studies of adults have shown an increased prevalence of celiac disease among patients with irritable bowel syndrome (IBS); few data are available with regard to children. To assess the prevalence of celiac disease among children with abdominal pain...

Sildenafil use and increased risk of incident melanoma in US men: a prospective cohort ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178948
JAMA Internal Medicine; Li WQ, Qureshi AA et. al.

Apr 8th, 2014 - The RAS/RAF/mitogen-activated protein kinase and extracellular signal-regulated kinase (ERK) kinase/ERK cascade plays a crucial role in melanoma cell proliferation and survival. Sildenafil citrate (Viagra) is a phosphodiesterase (PDE) 5A inhibitor commonly used for erectile dysfunction. Recent studies have shown that BRAF activation down-regulates PDE5A levels, and low PDE5A expression by BRAF ...

Screening for suicide risk in adolescents, adults, and older adults in primary care: U....
https://doi.org/10.7326/M14-0589
Annals of Internal Medicine; LeFevre ML,

May 20th, 2014 - Update of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for suicide risk. The USPSTF reviewed the evidence on the accuracy and reliability of instruments used to screen for increased suicide risk, benefits and harms of screening for increased suicide risk, and benefits and harms of treatments to prevent suicide. This recommendation applies to adolescents, adu...

Duration and course of post-concussive symptoms.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531270
Pediatrics Eisenberg MA, Meehan WP et. al.

May 13th, 2014 - To examine the incidence, duration, and clinical course of individual post-concussive symptoms in patients presenting to a pediatric emergency department (ED) with a concussion. We conducted secondary analysis of a prospective cohort study of patients 11 to 22 years old presenting to the ED of a children's hospital with an acute concussion. The main outcome measure was duration of symptoms, ass...

Psychiatric comorbidity and psychosocial impairment among patients with vertigo and diz...
https://doi.org/10.1136/jnnp-2014-307601
Journal of Neurology, Neurosurgery, and Psychiatry; Lahmann C, Henningsen P et. al.

Jun 25th, 2014 - Vertigo and dizziness are often not fully explained by an organic illness, but instead are related to psychiatric disorders. This study aimed to evaluate psychiatric comorbidity and assess psychosocial impairment in a large sample of patients with a wide range of unselected organic and non-organic (ie, medically unexplained) vertigo/dizziness syndromes. This cross-sectional study involved a sam...

Lanreotide in metastatic enteropancreatic neuroendocrine tumors.
https://doi.org/10.1056/NEJMoa1316158
The New England Journal of Medicine; Caplin ME, Pavel M et. al.

Jul 11th, 2014 - Somatostatin analogues are commonly used to treat symptoms associated with hormone hypersecretion in neuroendocrine tumors; however, data on their antitumor effects are limited. We conducted a randomized, double-blind, placebo-controlled, multinational study of the somatostatin analogue lanreotide in patients with advanced, well-differentiated or moderately differentiated, nonfunctioning, somat...

Musculoskeletal complications in type 1 diabetes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067398
Diabetes Care; Larkin ME, Barnie A et. al.

Apr 11th, 2014 - The development of periarticular thickening of skin on the hands and limited joint mobility (cheiroarthropathy) is associated with diabetes and can lead to significant disability. The objective of this study was to describe the prevalence of cheiroarthropathy in the well-characterized Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) c...

Fecal microbiota transplant for treatment of Clostridium difficile infection in immunoc...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537742
The American Journal of Gastroenterology; Kelly CR, Ihunnah C et. al.

Jun 3rd, 2014 - Patients who are immunocompromised (IC) are at increased risk of Clostridium difficile infection (CDI), which has increased to epidemic proportions over the past decade. Fecal microbiota transplantation (FMT) appears effective for the treatment of CDI, although there is concern that IC patients may be at increased risk of having adverse events (AEs) related to FMT. This study describes the mult...

Transverse vaginal septae: management and long-term outcomes.
https://doi.org/10.1111/1471-0528.12899
BJOG : an International Journal of Obstetrics and Gynaeco... Williams CE, Nakhal RS et. al.

Jun 19th, 2014 - To examine the management and long-term outcomes of transverse vaginal septae. Observational study with cross-sectional and retrospective arms. Tertiary referral centre specialising in Müllerian anomalies. Forty-six girls and women with a transverse vaginal septum. Data from medical records of all cases (1998-2013) of transverse vaginal septae were collected and reviewed. Patients over 16 years...

Mepolizumab treatment in patients with severe eosinophilic asthma.
https://doi.org/10.1056/NEJMoa1403290
The New England Journal of Medicine; Ortega HG, Liu MC et. al.

Sep 9th, 2014 - Some patients with severe asthma have frequent exacerbations associated with persistent eosinophilic inflammation despite continuous treatment with high-dose inhaled glucocorticoids with or without oral glucocorticoids. In this randomized, double-blind, double-dummy study, we assigned 576 patients with recurrent asthma exacerbations and evidence of eosinophilic inflammation despite high doses o...

A bioresorbable everolimus-eluting scaffold versus a metallic everolimus-eluting stent ...
https://doi.org/10.1016/S0140-6736(14)61455-0
Lancet (London, England); Serruys PW, Chevalier B et. al.

Sep 18th, 2014 - Despite rapid dissemination of an everolimus-eluting bioresorbable scaffold for treatment for coronary artery disease, no data from comparisons with its metallic stent counterpart are available. In a randomised controlled trial we aimed to compare an everolimus-eluting bioresorbable scaffold with an everolimus-eluting metallic stent. Here we report secondary clinical and procedural outcomes aft...

Acupuncture for chronic knee pain: a randomized clinical trial.
https://doi.org/10.1001/jama.2014.12660
JAMA Hinman RS, McCrory P et. al.

Sep 30th, 2014 - There is debate about benefits of acupuncture for knee pain. To determine the efficacy of laser and needle acupuncture for chronic knee pain. Zelen-design clinical trial (randomization occurred before informed consent), in Victoria, Australia (February 2010-December 2012). Community volunteers (282 patients aged ≥50 years with chronic knee pain) were treated by family physician acupuncturists. ...

Low-risk diet and lifestyle habits in the primary prevention of myocardial infarction i...
https://doi.org/10.1016/j.jacc.2014.06.1190
Journal of the American College of Cardiology; Akesson A, Larsson SC et. al.

Sep 26th, 2014 - Adherence to a combination of healthy dietary and lifestyle practices may have an impressive impact on the primary prevention of myocardial infarction (MI). The aim of this study was to examine the benefit of combined low-risk diet and healthy lifestyle practices on the incidence of MI in men. The population-based, prospective cohort of Swedish men comprised 45- to 79-year-old men who completed...

Quality-of-life outcomes with coronary artery bypass graft surgery in ischemic left ven...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182862
Annals of Internal Medicine; Mark DB, Knight JD et. al.

Sep 15th, 2014 - The STICH (Surgical Treatment for Ischemic Heart Failure) trial compared a strategy of routine coronary artery bypass grafting (CABG) with guideline-based medical therapy for patients with ischemic left ventricular dysfunction. To describe treatment-related quality-of-life (QOL) outcomes, a major prespecified secondary end point in the STICH trial. Randomized trial. (ClinicalTrials.gov: NCT0002...

Prospective evaluation of ursodeoxycholic acid withdrawal in patients with primary scle...
https://doi.org/10.1002/hep.27074
Hepatology (Baltimore, Md.); Wunsch E, Trottier J et. al.

Feb 12th, 2014 - Ursodeoxycholic acid (UDCA) is no longer recommended for management of adult patients with primary sclerosing cholangitis (PSC). We undertook a prospective evaluation of UDCA withdrawal in a group of consecutive patients with PSC. Twenty six patients, all treated with UDCA (dose range: 10-15 mg/kg/day) were included. Paired blood samples for liver biochemistry, bile acids, and fibroblast growth...

The evolution of sexual dysfunction in young men aged 18-25 years.
https://doi.org/10.1016/j.jadohealth.2014.05.014
The Journal of Adolescent Health : Official Publication O... Akre C, Berchtold A et. al.

Jul 19th, 2014 - To assess the evolution of sexual dysfunctions among young males after an average of 15 months follow-up to determine the predictive factors for this evolution and the characteristics differentiating young males who continue reporting a sexual dysfunction from those who do not. We conducted a prospective cohort study in two Swiss military recruitment centers mandatory for all Swiss national mal...