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About 447,520 results

Effectiveness and economic impact of a diabetes education program among adults with typ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427843
BMC Public Health; Smith ML, Zhong L et. al.

Sep 11th, 2021 - The long-term growth and sustained high prevalence of obesity in the US is likely to increase the burden of Type 2 diabetes. Hispanic individuals are particularly burdened by a larger share of diabetes than non-Hispanic White individuals. Given the existing health disparities facing this population, we aimed to examine the effectiveness and potential cost savings of the Diabetes Education Progr...

Personal Passive Air Samplers for Chlorinated Gases Generated from the Use of Consumer ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8430877
International Journal of Environmental Research and Publi... Ha Y, Koo Y et. al.

Sep 11th, 2021 - Various chlorine-based disinfectants are being used during the COVID-19 pandemic; however, only a few studies on exposure to harmful gases resulting from the use of these disinfectants exist. Previously, we developed a personal passive air sampler (PPAS) to estimate the exposure level to chlorine gas while using chlorinated disinfectants. Herein, we investigated the color development of the pas...

Application of the amplification-free SERS-based CRISPR/Cas12a platform in the identifi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424404
Journal of Nanobiotechnology; Liang J, Teng P et. al.

Sep 10th, 2021 - The control of contagious or refractory diseases requires early, rapid diagnostic assays that are simple, fast, and easy-to-use. Here, easy-to-implement CRISPR/Cas12a-based diagnostic platform through Raman transducer generated by Raman enhancement effect, term as SERS-CRISPR (S-CRISPR), are described. The S-CRISPR uses high-activity noble metallic nanoscopic materials to increase the sensitivi...

Prediction of the severity of colorectal lesion by fecal hemoglobin concentration obser...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384754
World Journal of Gastroenterology; Balamou C, Koïvogui A et. al.

Sep 10th, 2021 - The rate of positive tests using fecal immunochemical test (FIT) does not decrease with subsequent campaigns, but the positive predictive value of advanced neoplasia significantly decreases in subsequent campaign after a first negative test. A relationship between the fecal hemoglobin concentration (Fhb) and the opportunity to detect a colorectal cancer in subsequent campaign has been shown. To...

Long-term exposure to particulate air pollution and black carbon in relation to natural...
https://doi.org/10.1136/bmjopen-2020-046040
BMJ Open; Nilsson Sommar J, Andersson EM et. al.

Sep 10th, 2021 - To estimate concentration-response relationships for particulate matter (PM) and black carbon (BC) in relation to mortality in cohorts from three Swedish cities with comparatively low pollutant levels. Cohorts from Gothenburg, Stockholm and Umeå, Sweden. High-resolution dispersion models were used to estimate annual mean concentrations of PM with aerodynamic diameter ≤10 µm (PM10) and ≤2.5 µm (...

Vaccinia virus-based vaccines confer protective immunity against SARS-CoV-2 virus in Sy...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428573
PloS One; Kulkarni R, Chen WC et. al.

Sep 10th, 2021 - COVID-19 in humans is caused by Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that belongs to the beta family of coronaviruses. SARS-CoV-2 causes severe respiratory illness in 10-15% of infected individuals and mortality in 2-3%. Vaccines are urgently needed to prevent infection and to contain viral spread. Although several mRNA- and adenovirus-based vaccines are highly effective...

Association of coagulation disturbances with severity of COVID-19: a longitudinal study.
https://doi.org/10.1080/16078454.2021.1968648
Hematology (Amsterdam, Netherlands); Lu H, Chen M et. al.

Sep 9th, 2021 - Coagulation dysfunction is an evident factor in the clinical diagnosis and treatment of patients with coronavirus disease 2019 (COVID-19), appearing even in COVID-19 patients with normal inflammation indices. Therefore, this study aimed to analyze the characteristics of coagulation function indices in COVID-19 patients to investigate possible mechanisms through the comparison of non-severe and ...

Increased risk of periodontitis occurrence in patients with rheumatoid arthritis and it...
https://doi.org/10.21037/apm-21-1782
Annals of Palliative Medicine; Xiao F, Li C et. al.

Sep 8th, 2021 - Periodontitis (PD) is a chronic inflammatory disease caused by infection of the periodontal supporting tissues. Clinical studies have reported that rheumatoid arthritis (RA) patients have a higher prevalence of PD. This study aimed to explore the correlation between RA and PD. A total of 307 RA patients (RA group) and 324 healthy individuals (control group) who received physical examinations du...

Freak US winters linked to Arctic warming.
https://doi.org/10.1038/d41586-021-02402-z 10.1126/science.abi9167
Nature Schiermeier Q

Sep 5th, 2021 - Freak US winters linked to Arctic warming.|2021|Schiermeier Q,|analysis,adverse effects,adverse effects,statistics & numerical data,

The correlation of antioxidant levels of breast cancer: A case controlled study.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415973
Medicine Khalaf MY, Mohammed AA et. al.

Sep 4th, 2021 - Many free radicles are implicated to activate a number of oncogenic signaling, cause damage to deoxyribonucleic acid and tumor suppressor genes, or promote expression of proto-oncogenes. Reduced level of antioxidants and increases oxidative stress markers are associated with the development of various types of cancer.This prospective study included 60 women who were grouped into equal groups. P...

Prognostic significance of long non coding maternally expressed gene 3 in pediatric acu...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415930
Medicine Xue H, Gao H et. al.

Sep 4th, 2021 - The purpose of this study was to evaluate the correlation of long non-coding RNA maternally expressed gene 3 (Lnc-MEG3) with disease features, treatment response, and survival in pediatric acute myeloid leukemia (AML) patients.Among 92 de novo pediatric AML patients (before treatment and after 1 course of induction) and 40 controls, bone marrow mononuclear cells were obtained. Then, Lnc-MEG3 ex...

Longitudinal assessment of amyloid-beta deposition in initially amyloid-negative non-de...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416000
Medicine Hatashita S, Wakebe D

Sep 4th, 2021 - This study aimed to assess the longitudinal changes in amyloid beta (Aβ) deposition in cortical regions with [11C]-PIB PET in initially amyloid-negative non-demented subjects and evaluate whether amyloid-negative subjects convert to amyloid-positive.Sixteen cognitively normal (CN) and 7 mild cognitive impairment (MCI) subjects (aged 60-75 years), who were amyloid-negative at baseline, underwent...

Prolidase expression in knee osteoarthritis and healthy controls: Observational study.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415933
Medicine Silva-Luna K, Ventura-Ríos L et. al.

Sep 4th, 2021 - Prolidase enzyme activity is important for collagen resynthesis. In late stages of osteoarthritis (OA) its activity is decreased.To evaluate prolidase expression in knees of patients undergoing total arthroplasty for OA, and compare with young people undergoing knee arthroscopy due to traumatic injuries.In this cross-sectional study we included 20 patients with OA grade IV who underwent total k...

Natural course of hemoglobin level after total knee arthroplasty and the benefit of tra...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415948
Medicine Cho MR, Jun CM et. al.

Sep 4th, 2021 - We retrospectively investigated the natural course of hemoglobin (Hb) level after total knee arthroplasty (TKA) and identified the benefit of tranexamic acid injection at the operation field for unilateral TKA patients who have not received blood transfusions.There were 115 cases conducted by a surgeon who performed TKA without injecting tranexamic acid and 62 cases by another surgeon with inje...

Prognostic significance of volume-based 18F-FDG PET/CT parameters and correlation with ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415941
Medicine Wang D, Li Y et. al.

Sep 4th, 2021 - The aim of this study was to retrospectively analyze 18F-FDG positron emission tomography/computed tomography (18F-FDG PET/CT) metabolic variables, programmed death-ligand 1 (PD-L1) and phosphorylated signal transducer and activator of transcription 3 (p-STAT3) tumor expression, and other factors as predictors of disease-free survival (DFS) in patients with lung adenocarcinoma (LUAD) (stage IA-...

PD-L1 Expression and Clinicopathological Factors in Renal Cell Carcinoma: A Comparison ...
https://doi.org/10.21873/anticanres.15271
Anticancer Research; Ikeda J, Ohe C et. al.

Sep 4th, 2021 - Expression of programmed death ligand-1 (PD-L1) is associated with poor prognosis in renal cell carcinoma (RCC). Although a new antibody clone for immunohistochemical assay, 73-10, has shown greater sensitivity than other assays (28-8, 22C3, SP142, and SP263) in non-small cell lung cancer, PD-L1 expression using 73-10 has never been assessed in RCC. Therefore, this study aimed to evaluate the a...

Serum level of high sensitive C-reactive protein and IL - 6 markers in patients with tr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406754
BMC Psychiatry; Challa F, Seifu D et. al.

Sep 2nd, 2021 - Accumulating evidence indicates that schizophrenia is accompanied by significant activation of the immune system; however, there is limited data from low and middle-income countries (LMIC). Inflammatory markers may be more relevant in LMIC settings where infectious conditions are more prevalent and may thus play some role in the causation and maintenance of schizophrenia. The aim of this study ...

SalmoSim: the development of a three-compartment in vitro simulator of the Atlantic sal...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8408954
Microbiome Kazlauskaite R, Cheaib B et. al.

Sep 2nd, 2021 - The aquaculture sector now accounts for almost 50% of all fish for human consumption and is anticipated to provide 62% by 2030. Innovative strategies are being sought to improve fish feeds and feed additives to enhance fish performance, welfare, and the environmental sustainability of the aquaculture industry. There is still a lack of knowledge surrounding the importance and functionality of th...

Tempering of cocoa butter and chocolate using minor lipidic components.
https://doi.org/10.1038/s41467-021-25206-1 10.1007/BF02577842 10.1039/C1SM06234D 10.1016/S0009-2509(00)00458-9 10.1111/j.1365-2621.2004.tb09933.x 10.1007/BF02663754 10.5539/jfr.v7n5p86 10.1007/s11746-011-1819-7 10.1007/s11746-007-1130-9 10.1007/BF02641273 10.1002/ejlt.201100088 10.1021/acs.cgd.8b01268 10.1007/BF02637399 10.1021/cg025580l 10.1007/BF02638052 10.1007/s11746-000-0122-5 10.1111/j.1365-2621.2005.tb11491.x 10.1107/S1600577516010195 10.1046/j.1365-2818.2002.01010.x
Nature Communications; Chen J, Ghazani SM et. al.

Sep 2nd, 2021 - Chocolate manufacture includes a complex tempering procedure to direct the crystallization of cocoa butter towards the formation of fat crystal networks with specific polymorphism, nano- and microstructure, melting behavior, surface gloss and mechanical properties. Here we investigate the effects of adding various minor non-triglyceride lipidic components to refined cocoa butter and chocolate o...

Paediatric post-COVID-19 hyperinflammatory syndrome mimicking appendicitis: a case series.
https://doi.org/10.1308/rcsann.2021.0132
Annals of the Royal College of Surgeons of England; Coles V, Yardley I et. al.

Sep 1st, 2021 - A novel hyperinflammatory syndrome has emerged in the paediatric population: paediatric inflammatory multisystem syndrome - temporally associated with SARS-CoV-2 (PIMS-TS). Up to 50% of patients develop shock with cardiac dysfunction but presentation with acute abdominal pain is common and difficult to distinguish from appendicitis. Prospective case series of PIMS-TS patients presenting to a si...