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About 254,155 results

Patient reported outcomes and disability are associated with histological disease activ...
https://doi.org/10.1093/ecco-jcc/jjad015
Journal of Crohn's & Colitis; Verstockt B, Pouillon L et. al.

Jan 29th, 2023 - Treating beyond endoscopic remission, aiming for histological remission, is an emerging target in ulcerative colitis (UC). Patient reported outcome measurements (PROMs) become increasingly important, but its association with histology is unclear. Multiple PROMs were prospectively collected in UC patients undergoing colonoscopy. Mayo endoscopic sub-score (MES) and UCEIS were determined, as well ...

Contrast-enhanced ultrasound pattern of hepatocellular carcinoma in noncirrhotic liver ...
https://doi.org/10.1097/MEG.0000000000002491
European Journal of Gastroenterology & Hepatology; Schellhaas B, Jesper D et. al.

Jan 29th, 2023 - Contrast-enhanced ultrasound (CEUS) has a high diagnostic accuracy for the noninvasive diagnosis of hepatocellular carcinoma (HCC) in cirrhosis. However, as HCC in noncirrhosis becomes an emerging clinical concern, our study aimed to assess the diagnostic value of CEUS and the CEUS algorithms CEUS LI-RADS and ESCULAP in noncirrhotic liver in a prospective multicentre real-life setting. High-ris...

High resolution dermal ultrasound (US) combined with superficial radiation therapy (SRT...
https://doi.org/10.1186/s12885-023-10577-z
BMC Cancer; Yu L, Moloney M et. al.

Jan 29th, 2023 - To compare the effectiveness of high-resolution dermal ultrasound (US) guided superficial radiotherapy (SRT) to non-image-guided radiotherapy in the treatment of early-stage Non-Melanoma Skin Cancer (NMSC). A high-resolution dermal ultrasound (US) image guided form of superficial radiation therapy (designated here as US-SRT) was developed in 2013 where the tumor configuration and depth can be v...

Is it possible to predict the severity of acute appendicitis? Reliability of predictive...
https://doi.org/10.1186/s13017-023-00478-8
World Journal of Emergency Surgery : WJES; Afzal B, Cirocchi R et. al.

Jan 29th, 2023 - Recent evidence confirms that the treatment of acute appendicitis is not necessarily surgical, and selected patients with uncomplicated appendicitis can benefit from a non-operative management. Unfortunately, no cost-effective test has been proven to be able to effectively predict the degree of appendicular inflammation as yet, therefore, patient selection is too often left to the personal choi...

Comparison of the sensitivity of different criteria to select lung cancer patients for ...
https://doi.org/10.1002/cam4.5638
Cancer Medicine; Walter J, Kauffmann-Guerrero D et. al.

Jan 29th, 2023 - Trials of CT-based screening for lung cancer have shown a mortality advantage for screening in North America and Europe. Before introducing a nationwide lung cancer screening program in Germany, it is important to assess the criteria used in international trials in the German population. We used data from 3623 lung cancer patients from the data warehouse of the German Center for Lung Research (...

TRPA1 is involved in the inhibitory effect of Ke-teng-zi on allergic contact dermatitis...
https://doi.org/10.1016/j.jep.2023.116182
Journal of Ethnopharmacology; Ju Y, Luo M et. al.

Jan 28th, 2023 - The seeds of Entada phaseoloides (Linn.) Merr. commonly named "Ke-teng-zi" are a traditional Chinese folk medicine and reported to treat dermatitis, spasm, and headache. However, the exact effect and the mechanism of Ke-teng-zi on the treatment of dermatitis are unclear. To elucidate the antipruritic effect and molecular mechanisms of Ke-teng-zi on the treatment of allergic contact dermatitis (...

Orbital and periocular complications in patients with sinonasal tumours with orbital in...
https://doi.org/10.1136/bjo-2022-322855
The British Journal of Ophthalmology; Zhao J, Jiang X et. al.

Jan 28th, 2023 - The purpose of this study was to determine the frequency and associated risk factors of orbital/periocular complications in patients with sinonasal tumour with orbital invasion managed with eye-sparing treatments. A retrospective case series of patients with primary sinonasal tumour with orbital invasion from January 2008 to December 2018. Patient factors were compared between the following gro...

Genomic and epigenomic re-categorization of congenital glioblastoma and desmoplastic in...
https://doi.org/10.1007/s00381-023-05848-w
Child's Nervous System : ChNS : Official Journal of the I... Gilani A, Siddiq Z et. al.

Jan 28th, 2023 - The recently updated World Health Organization classification of central nervous system (CNS) tumors, 5th edition, (CNS5) reclassifies pediatric tumors according to their distinct molecular drivers, recognizing a new entity-infant-type hemispheric glioma (IHG). Defined by its unique epigenetic signature, and/or genomic fusions in ALK, ROS1, NTRK, or MET gene, IHG subsumes many cases previously ...

Histological and Radiological Assessment of Endogenously Generated Repair Tissue In Viv...
https://doi.org/10.1177/19476035221149523
Cartilage McCarthy HS, Tins B et. al.

Jan 28th, 2023 - To examine repair tissue formed approximately 15 months after a chondral harvest in the human knee. Sixteen individuals (12 males, 4 females, mean age 36 ± 9 years) underwent a chondral harvest in the trochlea as a pre-requisite for autologous chondrocyte implantation (ACI) treatment. The harvest site was assessed via MRI at 14.3 ± 3.2 months and arthroscopy at 15 ± 3.5 months (using the Oswest...

Neoadjuvant chemotherapy in advanced epithelial ovarian cancer by histology: A SEER bas...
https://doi.org/10.1097/MD.0000000000032774
Medicine Liu Y, Ni M et. al.

Jan 28th, 2023 - To evaluate the prognostic effect of neoadjuvant chemotherapy (NACT) in advanced epithelial ovarian cancer (EOC) patients with different histological subtype. Stage III/IV EOC patients diagnosed between 2010 and 2018 were identified from the surveillance, epidemiology, and end results database (SEER) database and stratified by histological subtype. Kaplan-Meier analysis was used for the assessm...

The correlation of Th22 and regulatory T cells with Helicobacter pylori infection in pa...
https://doi.org/10.1002/iid3.768
Immunity, Inflammation and Disease; Yao B, Xu X et. al.

Jan 28th, 2023 - Helicobacter pylori is planted in the human stomach and is the most common cause of chronic gastritis, which produced specific local and systemic humoral immunity, while the associations of these immune responses and H. pylori in the development of chronic gastritis remain unclear. This study analyzed histology, the number of Th22 and regulatory T (Treg) cells, and the levels of inflammation- a...

Protocol biopsies in pediatric liver transplantation recipients improve graft histology...
https://doi.org/10.1097/MPG.0000000000003707
Journal of Pediatric Gastroenterology and Nutrition; Karbaum E, Weidemann S et. al.

Jan 28th, 2023 - Protocol liver biopsies (PLB) are part of the follow-up program at many pediatric liver transplant centers, but the impact on clinical decision-making and allograft histology following adjustments of immunosuppression (IS) after PLB has not been thoroughly analyzed. Following our previous single-center cohort study, we have now evaluated histological findings of 178 PLPs of 118 pediatric patien...

One single drug-coated balloon for all shapes/diameters? Neointimal proliferation inhib...
https://doi.org/10.1371/journal.pone.0280206
PloS One; Bienek S, Kusmierczuk M et. al.

Jan 28th, 2023 - Long diseased vessel segments of peripheral arteries may display irregular shapes with different diameters. The aim of this study was to investigate inhibition of neointimal proliferation in porcine peripheral vessels with different diameters covered by one single hyper-compliant drug-coated balloon (HCDCB), compared to conventional drug-coated balloons (DCB), each selected according to the res...

18FFDG PET/CT in a Case of Mycosis Fungoides Showing an Unusual Adverse Reaction to Mog...
https://doi.org/10.1089/cbr.2022.0086
Cancer Biotherapy & Radiopharmaceuticals; Filippi L, Proietti I et. al.

Jan 28th, 2023 - A 73-year-old female patient, affected by mycosis fungoides (MF), discontinued mogamulizumab, after initial clinical benefit, due to the onset of generalized erythema. Follow-up positron emission computed tomography (PET/CTs) carried out at 3 weeks and 6 months after therapy discontinuation showed, with respect to baseline PET/CT scan, a progressively increasing number of hypermetabolic enlarge...

Presentation, medical complications and development of gestational trophoblastic neopla...
https://doi.org/10.1016/j.ygyno.2023.01.016
Gynecologic Oncology; Braga A, Andrade T et. al.

Jan 28th, 2023 - To describe the natural history of hydatidiform mole (HM) after intracytoplasmic sperm injection (ICSI), emphasizing the clinical and oncological outcomes, as compared to patients who had HM after spontaneous conception (SC). Retrospective historical cohort study of patients with HM followed at the Rio de Janeiro Federal University, from January 1st 2000-December 31st 2020. Comparing singleton ...

Systematic review and synthesis of stillbirths and late miscarriages following SARS-CoV...
https://doi.org/10.1016/j.ajog.2023.01.019
American Journal of Obstetrics and Gynecology; Alcover N, Regiroli G et. al.

Jan 28th, 2023 - To describe the characteristics of fetal demises following SARS-CoV-2 infections and clarify if they are associated with clinical severity, placental lesions or malformations or due to actual fetal infections. PubMed and Web of Science databases (searched between December 1, 2019 and April 30, 2022). Cohort, cross-sectional and case-control studies, as well as case series or case reports descri...

Alpha-adrenergic receptor activation after fetal hypoxia-ischaemia suppresses transient...
https://doi.org/10.1177/0271678X231153723
Journal of Cerebral Blood Flow and Metabolism : Official ... Dhillon SK, Gunn ER et. al.

Jan 28th, 2023 - Exposure to hypoxic-ischaemia (HI) is consistently followed by a delayed fall in cerebral perfusion. In preterm fetal sheep this is associated with impaired cerebral oxygenation, consistent with mismatch between perfusion and metabolism. In the present study we tested the hypothesis that alpha-adrenergic inhibition after HI would improve cerebral perfusion, and so attenuate mismatch and reduce ...

Preoperative and intraoperative assessment of myometrial invasion in patients with FIGO...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878924
Diagnostic Pathology; Yang X, Yin J et. al.

Jan 27th, 2023 - Myometrial invasion is a prognostic factor for lymph node metastases and decreased survival in non-endometrioid endometrial carcinoma patients. Herein, we explored the mode of myometrial invasion diagnosis in FIGO stage I non-endometrioid carcinoma and evaluated the differences in diagnostic efficiency among intraoperative frozen section (IFS), intraoperative gross examination (IGE), magnetic r...

Association of Hospital Surgical Volume With Survival in Early-Stage Cervical Cancer Tr...
https://doi.org/10.1097/AOG.0000000000005026
Obstetrics and Gynecology; Bizzarri N, Dostálek L et. al.

Jan 27th, 2023 - To evaluate the association of number of radical hysterectomies performed per year in each center with disease-free survival and overall survival. We conducted an international, multicenter, retrospective study of patients previously included in the Surveillance in Cervical Cancer collaborative studies. Individuals with International Federation of Gynecology and Obstetrics (FIGO) 2009 stage IB1...

Human papillomavirus status and prognosis of oropharyngeal high-grade neuroendocrine ca...
https://doi.org/10.1016/j.oraloncology.2023.106311
Oral Oncology; de Sousa LG, Lazar Neto F et. al.

Jan 27th, 2023 - The prognostic impact of human papillomavirus (HPV) infection or smoking on oropharyngeal high-grade neuroendocrine carcinoma (HG-NEC) is not established. Retrospective study with patients with oropharyngeal HG-NEC seen at MD Anderson Cancer Center from 1997 to 2020, and previously reported patients with oropharyngeal HG-NEC and known p16 and HPV status from the literature review. Survival was ...