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About 1,182,918 results

New Drug Shows Promise for Levodopa-Induced Dyskinesia
https://www.parkinson.org/blog/science-news/New-Drug-Shows-Promise-for-Levodopa-Induced-Dyskinesia

People with Parkinson’s disease (PD) commonly suffer from tremors and other movement symptoms, such as slowness and stiffness, caused by the loss of dopamine-producing nerve cells in an area of the brain called the substantia nigra. The cornerstone therapy for reducing these symptoms is the drug, levodopa. Often referred to as simply L-dopa, this drug works by helping to replenish the brain’s s...

Healthcare Ready
https://healthcareready.org/

Healthcare Ready (formerly Rx Response) helps to strengthen healthcare supply chains through collaboration with public health and private sectors by addressing pressing issues before, during, and after disasters. As the convener of industry and government, we safeguard patient health by providing solutions to critical problems. And, we provide best practices for healthcare preparedness and resp...

Optimizing Supply of PPE and Other Equipment during Shortages
https://www.cdc.gov/coronavirus/2019-ncov/hcp/ppe-strategy/index.html
CDC

Personal protective equipment (PPE) is used every day by healthcare personnel (HCP) to protect themselves, patients, and others when providing care. PPE helps protect HCP from many hazards encountered in healthcare facilities. The greatly increased need for PPE caused by the COVID-19 pandemic has caused PPE shortages, posing a tremendous challenge to the U.S. healthcare system. Healthcare fa...

N95 Mask Decontamination using Standard Hospital Sterilization Technologies
https://www.medrxiv.org/content/10.1101/2020.04.05.20049346v2.full.pdf

The response to the COVID-19 epidemic is generating severe shortages of personal protective equipment around the world. In particular, the supply of N95 respirator masks has become severely depleted, with supplies having to be rationed and health care workers having to use masks for prolonged periods in many countries. We sought to test the ability of 5 different decontamination methods: au...

Face mask use in the general population and optimal resource allocation during the COVID-19 pandemic
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426871/

The ongoing novel coronavirus disease (COVID-19) pandemic has already infected millions worldwide and, with no vaccine available, interventions to mitigate transmission are urgently needed. While there is broad agreement that travel restrictions and social distancing are beneficial in limiting spread, recommendations around face mask use are inconsistent. Here, we use mathematical modeling to e...

Monkeypox: Fractional vaccine doses will be piloted as new treatment trial launches
https://www.bmj.com/content/378/bmj.o2080
BMJ Mahase E.

Aug 23rd, 2022 - Smaller doses of the smallpox vaccine, used to provide protection against monkeypox, will be piloted at NHS sites in London and Manchester to maximise supply, the UK Health Security Agency (UKHSA) has announced. In the pilot scheme—which will take place at Chelsea and Westminster NHS Foundation Trust, Central and North West London NHS Foundation Trust, and Locala Health and Wellbeing in Grea...

Will COVID-19 Threaten Availability and Affordability of our Food?
https://www.usda.gov/media/blog/2020/04/16/will-covid-19-threaten-availability-and-affordability-our-food

As the COVID-19 virus continues to spread in the U.S., its impacts have reached every aspect of our lives and shook all sectors of the economy. Amid this crisis, there have been widespread worries that the disease could threaten the nation’s food production and supply systems and stoke inflation. Many began to wonder whether the food they need will continue to be available and affordable as we ...

Proper N95 Respirator Use for Respiratory Protection Preparedness
https://blogs.cdc.gov/niosh-science-blog/2020/03/16/n95-preparedness/

To aid healthcare facilities experiencing shortages of N95 respirators due to high demand across the nation, CDC developed the Strategies for Optimizing the Supply of N95 Respirators in Healthcare Settings which provides options on how to optimize supplies of disposable N95 filtering facepiece respirators (commonly called “N95 respirators”) in healthcare settings when there is limited supply.

Food Supply Chain USDA
https://www.usda.gov/coronavirus/food-supply-chain

Access to Food

Critical Shortage of Dextrose Is Forcing EMS to Adapt Protocols
https://www.hstoday.us/subject-matter-areas/emergency-preparedness/critical-shortage-of-dextrose-is-forcing-ems-to-adapt-protocols/
Homeland Security Today;

Jul 22nd, 2022 - The Food and Drug Administration is currently reporting shortages of dextrose in 5%, 10%, 25% and 50% solutions. Manufacturing capacity to support these dextrose products is not expected to improve for some time. There is potential for shortages of these products to worsen if anything else disrupts the supply.

There’s a shortage of monkeypox vaccine. Could one dose instead of two suffice?
https://www.science.org/content/article/there-s-shortage-monkeypox-vaccine-could-one-dose-instead-two-suffice
Science Cohen J.

Jul 1st, 2022 - As the monkeypox outbreak grows, the preferred vaccine to combat it is in short supply—a problem that’s only getting worse now that countries are expanding access to the vaccine. But there is a strategy that could double overnight the number of people who can be vaccinated: use a single shot instead of the recommended two.

Development of summer skiing days in Austrian glacier ski areas in the first two decade...
https://doi.org/10.1007/s00484-022-02371-6
International Journal of Biometeorology; Mayer M, Abegg B

Oct 2nd, 2022 - Summer skiing on glaciers is a leisure activity highly dependent on natural factors like weather and glacier conditions. While the literature agrees that climate change is shaping the fate of summer skiing, longer time series covering both the supply and demand side of glacier/summer skiing, and research that combines natural and non-natural factors affecting the summer ski market are missing. ...

A novel low-cost indigenous goggle design for oxygen delivery in oxygen supplemented ac...
https://doi.org/10.1177/11206721221128862
European Journal of Ophthalmology; Sinha R, Sabir M et. al.

Oct 2nd, 2022 - Our study aims to describe a novel low-cost indigenous design of goggles for delivery of oxygen during oxygen supplemented accelerated corneal collagen cross-linking (CXL). The goggles were prepared by modifying the safety goggles available in personal protective equipment (PPE) kit. The goggle has two side openings covered with plugs. One plug was removed to insert a tubing for oxygen delivery...

Co-occurrence patterns of adverse childhood experiences and their associations with non...
https://doi.org/10.1016/j.jad.2022.09.124
Journal of Affective Disorders; Xiao W, Rong F et. al.

Oct 2nd, 2022 - Previous research has found increasing evidence of adverse childhood experiences (ACEs) leading to non-suicidal self-injury (NSSI) and suicidal behaviors. Most studies have focused on a certain type or timing of ACEs or the patterns of multiple types; however, few of them have examined the patterns of ACEs combined types and timing and the gender differences in the association between ACEs and ...

Green Supply Chain Management and Its Impact on Economic-Environmental Performance: Evi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514937
Journal of Environmental and Public Health; Huang H

Oct 1st, 2022 - At present, with the increasing seriousness of ecological pollution, people are gradually paying more attention to the protection of the ecological environment. In the past, people only paid attention to economic growth and neglected environmental protection. Now, environmental problems have restricted economic development, leading scholars at home and abroad to reflect on it deeply. Supply cha...

The impact of COVID-19 on nurses (ICON) survey: Nurses' accounts of what would have hel...
https://doi.org/10.1111/jan.15442
Journal of Advanced Nursing; Ball J, Anstee S et. al.

Oct 1st, 2022 - To use nurses' descriptions of what would have improved their working lives during the first peak of the COVID-19 pandemic in the UK. Analysis of free-text responses from a cross-sectional survey of the UK nursing and midwifery workforce. Between 2 and 14 April 2020, 3299 nurses and midwives completed an online survey, as part of the 'Impact of COVID-19 on Nurses' (ICON) study. 2205 (67%) gave ...

The leptomeninges as a critical organ for normal CNS development and function: First pa...
https://doi.org/10.1371/journal.pone.0274634
PloS One; Palackdkharry CS, Wottrich S et. al.

Oct 1st, 2022 - This patient and public-involved systematic review originally focused on arachnoiditis, a supposedly rare "iatrogenic chronic meningitis" causing permanent neurologic damage and intractable pain. We sought to prove disease existence, causation, symptoms, and inform future directions. After 63 terms for the same pathology were found, the study was renamed Diseases of the Leptomeninges (DLMs). We...

Explosive COVID-19 outbreak in a German nursing home and the possible role of the air v...
https://doi.org/10.1016/j.jhin.2022.09.013
The Journal of Hospital Infection; Hurraß J, Golmohammadi R et. al.

Oct 1st, 2022 - Most COVID-19 outbreaks in nursing homes are explained by transmission of SARS-CoV-2 from nurses or visitors. We describe an outbreak with 64 of the 67 residents identified as COVID-19 cases within two weeks (34 in nursing block 1, 30 in nursing block 2), at least 32 of them had relevant symptoms of COVID-19. Thirteen of the residents died associated with COVID-19. In addition, 27 of approximat...

Digitally-enhanced lubricant evaluation scheme for hot stamping applications.
https://doi.org/10.1038/s41467-022-33532-1
Nature Communications; Yang X, Liu H et. al.

Oct 1st, 2022 - Digitally-enhanced technologies are set to transform every aspect of manufacturing. Networks of sensors that compute at the edge (streamlining information flow from devices and providing real-time local data analysis), and emerging Cloud Finite Element Analysis technologies yield data at unprecedented scales, both in terms of volume and precision, providing information on complex processes and ...

The future of fungi: threats and opportunities.
https://doi.org/10.1093/g3journal/jkac224
G3 (Bethesda, Md.); Case NT, Berman J et. al.

Oct 1st, 2022 - The fungal kingdom represents an extraordinary diversity of organisms with profound impacts across animal, plant, and ecosystem health. Fungi simultaneously support life, by forming beneficial symbioses with plants and producing life-saving medicines, and bring death, by causing devastating diseases in humans, plants, and animals. With climate change, increased antimicrobial resistance, global ...