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About 1,177,270 results

New Drug Shows Promise for Levodopa-Induced Dyskinesia
https://www.parkinson.org/blog/science-news/New-Drug-Shows-Promise-for-Levodopa-Induced-Dyskinesia

People with Parkinson’s disease (PD) commonly suffer from tremors and other movement symptoms, such as slowness and stiffness, caused by the loss of dopamine-producing nerve cells in an area of the brain called the substantia nigra. The cornerstone therapy for reducing these symptoms is the drug, levodopa. Often referred to as simply L-dopa, this drug works by helping to replenish the brain’s s...

Healthcare Ready
https://healthcareready.org/

Healthcare Ready (formerly Rx Response) helps to strengthen healthcare supply chains through collaboration with public health and private sectors by addressing pressing issues before, during, and after disasters. As the convener of industry and government, we safeguard patient health by providing solutions to critical problems. And, we provide best practices for healthcare preparedness and resp...

Optimizing Supply of PPE and Other Equipment during Shortages
https://www.cdc.gov/coronavirus/2019-ncov/hcp/ppe-strategy/index.html
CDC

Personal protective equipment (PPE) is used every day by healthcare personnel (HCP) to protect themselves, patients, and others when providing care. PPE helps protect HCP from many hazards encountered in healthcare facilities. The greatly increased need for PPE caused by the COVID-19 pandemic has caused PPE shortages, posing a tremendous challenge to the U.S. healthcare system. Healthcare fa...

N95 Mask Decontamination using Standard Hospital Sterilization Technologies
https://www.medrxiv.org/content/10.1101/2020.04.05.20049346v2.full.pdf

The response to the COVID-19 epidemic is generating severe shortages of personal protective equipment around the world. In particular, the supply of N95 respirator masks has become severely depleted, with supplies having to be rationed and health care workers having to use masks for prolonged periods in many countries. We sought to test the ability of 5 different decontamination methods: au...

Face mask use in the general population and optimal resource allocation during the COVID-19 pandemic
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426871/

The ongoing novel coronavirus disease (COVID-19) pandemic has already infected millions worldwide and, with no vaccine available, interventions to mitigate transmission are urgently needed. While there is broad agreement that travel restrictions and social distancing are beneficial in limiting spread, recommendations around face mask use are inconsistent. Here, we use mathematical modeling to e...

J&J pulls COVID vaccine sales forecast due to low demand, supply glut
https://www.reuters.com/business/johnson-johnson-suspends-sales-forecast-covid-19-vaccine-2022-04-19/
Reuters Mishra M, Erman M.

Apr 19th, 2022 - April 19 (Reuters) - Johnson & Johnson (JNJ.N) on Tuesday rescinded its forecast for sales of its COVID-19 vaccine, as hesitancy in low income countries has led to a glut of supply of a shot once hoped to be the inoculation of choice for the developing world.

Will COVID-19 Threaten Availability and Affordability of our Food?
https://www.usda.gov/media/blog/2020/04/16/will-covid-19-threaten-availability-and-affordability-our-food

As the COVID-19 virus continues to spread in the U.S., its impacts have reached every aspect of our lives and shook all sectors of the economy. Amid this crisis, there have been widespread worries that the disease could threaten the nation’s food production and supply systems and stoke inflation. Many began to wonder whether the food they need will continue to be available and affordable as we ...

Proper N95 Respirator Use for Respiratory Protection Preparedness
https://blogs.cdc.gov/niosh-science-blog/2020/03/16/n95-preparedness/

To aid healthcare facilities experiencing shortages of N95 respirators due to high demand across the nation, CDC developed the Strategies for Optimizing the Supply of N95 Respirators in Healthcare Settings which provides options on how to optimize supplies of disposable N95 filtering facepiece respirators (commonly called “N95 respirators”) in healthcare settings when there is limited supply.

Food Supply Chain USDA
https://www.usda.gov/coronavirus/food-supply-chain

Access to Food

Lilly will supply up to 600,000 doses of bebtelovimab to U.S. government in ongoing effort to provide COVID-19 treatment options
https://investor.lilly.com/news-releases/news-release-details/lilly-will-supply-600000-doses-bebtelovimab-us-government
Eli Lilly and Company

Feb 10th, 2022 - Bebtelovimab neutralizes Omicron as demonstrated by pseudovirus and authentic virus data Patients will continue to have no out-of-pocket costs for the medication

Milk yield variation partially attributed to blood oxygen-mediated neutrophil activatio...
https://doi.org/10.1017/S0007114522001015
The British Journal of Nutrition; Cai J, Liang S et. al.

May 24th, 2022 - Blood oxygen is an essential component for numerous biological processes of mammalian animals. Milk production of ruminants largely relies on the supply of nutrients, such as glucose, amino acids and fatty acids. To define the regulatory role of blood oxygen availability in regard to milk production, seventy-five healthy Guanzhong dairy goats with similar body weight, days in milk and parities ...

Fluctuations in food and fluid intake during a 24-h World Championship: analysis of the...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116402
Journal of the International Society of Sports Nutrition; Charlot K, Lavoué C et. al.

May 24th, 2022 - A food and fluid intake program is essential for ultraendurance athletes to maximize performance and avoid possible gastrointestinal symptoms (GIS). However, the ability to follow such a program during a race has been under-assessed. We thus investigated the fluctuations of food and fluid intake during the 24-h run World Championship of 12 elite athletes (6 men and 6 women; age: 46 ± 7 years, h...

Complementary feeding and food-group level inequality among Ethiopian children 6-23 mon...
https://doi.org/10.1111/mcn.13375
Maternal & Child Nutrition; Tizazu W, Laillou A et. al.

May 23rd, 2022 - Ensuring diet quality in the first 2 years of life is critical to preventing malnutrition and instilling healthy food preferences. Children's diet quality has changed little over time and inequalities by socioeconomic status, rural-urban residence, but also by food group may exist. Using data from the 2011, 2016 and 2019 demographic and health surveys (DHS), we estimated the prevalence and ineq...

Development and technical validation of an ultrasound nebulizer to deliver intraperiton...
https://doi.org/10.1186/s12885-022-09668-0 10.1016/S1470-2045(19)30318-3 10.1007/s00464-012-2148-0 10.1245/s10434-013-3213-1 10.3390/cancers12010034 10.1186/s12885-021-07955-w 10.1245/s10434-019-07695-z 10.1186/s12885-019-5658-5 10.1021/acsami.0c05554 10.21873/anticanres.11008 10.1007/s00464-016-5174-5 10.3762/bjnano.8.27 10.1002/jat.727 10.1515/pp-2016-0006 10.1038/s41598-021-01332-0 10.1002/ppsc.19850020102 10.1098/rsif.2005.0040 10.1186/s13550-015-0125-z 10.2174/2211555211302010004 10.1080/17425247.2021.1829590 10.1016/S0378-5173(97)00105-1 10.1007/s004649900486
BMC Cancer; Buggisch JR, Göhler D et. al.

May 22nd, 2022 - To develop and validate a nebulizer device for anti-cancer research on pressurized intraperitoneal aerosol supply in a preclinical peritoneal metastases (PM) rat model. For aerosol generation, an ultrasonic nebulizer (USN) was modified. Aerosol analyses were performed ex-vivo by laser diffraction spectrometry (LDS). Intraperitoneal (IP) 99mtechnetium sodium pertechnetate (99mTc) aerosol distrib...

Ascertaining the Readiness of Military Orthopedic Surgeons: A Revision to the Knowledge...
https://doi.org/10.1093/milmed/usac135
Military Medicine; Osborn PM, Tansey KA

May 22nd, 2022 - Decay of military surgeons' critical wartime skills is a persistent and growing concern among leaders in the military health system (MHS). The Knowledge, Skills and Abilities (KSA) Clinical Readiness Program was developed to quantify the readiness of clinicians in the MHS; however, the utility of the data is questionable due to a lack of focus on the operative expeditionary skillset in the orig...

Analysis of serological treatment response to doxycycline versus benzathine penicillin ...
https://doi.org/10.1111/dth.15586
Dermatologic Therapy; Zengarini C, Carpanese M et. al.

May 21st, 2022 - Doxycilicine is the second-line treatment of choice for infectious syphilis when treatment with penicillin G is not feasible. To date, difficulties in the penicillin supply chain make it necessary to evaluate and resort to antibiotic therapies which are currently considered a second-line choice. Moreover, systematic studies comparing the two treatments in affected patients are still few, and ma...

Laparoscopic ureteral reimplantation with a Boari flap for long-segment ureteric avulsi...
https://doi.org/10.1007/s11255-022-03224-2 10.1111/j.1464-410X.1973.tb12164.x 10.4111/icu.2020.61.S1.S23 10.1016/j.asjsur.2021.01.027 10.1177/1756287214526767 10.1007/s00120-019-0944-z 10.5152/tud.2017.44520 10.1016/j.eururo.2006.08.004 10.1016/j.acuro.2012.11.017 10.21037/tau-20-789 10.1016/j.urology.2017.07.014 10.1016/S0022-5347(01)66332-8 10.1111/iju.13353 10.1016/j.ucl.2013.04.005
International Urology and Nephrology; Zhang G, Zhao J et. al.

May 21st, 2022 - This study was designed to evaluate the feasibility of laparoscopic ureteral reimplantation with a Boari flap for long-segment ureteric avulsion or ureteric strictures of the middle and lower ureters. By observing its curative effect and prognosis, we can provide a safer and reliable treatment option for patients with middle and lower ureteral injury. In this study, of the eight cases under stu...

Inhibition of Glutamine Cellular Uptake Contributes to the Cytotoxic Effect of Xanthohu...
https://doi.org/10.1080/01635581.2022.2076889
Nutrition and Cancer; Carmo F, Silva C et. al.

May 21st, 2022 - Breast cancer constitutes the most incident cancer and one of the most common causes of cancer-related death. "Glutamine addiction", an important metabolic feature of cancer cells, is dependent on supply of this amino acid from external sources. In this study, the effect of several polyphenols (catechin, epicatechin, EGCG, catechin:lysine, naringenin, hesperidin, malvidin, delphinidin, kaempfer...

The characteristics of intracranial plaques of unilateral, anterior circulation embolic...
https://doi.org/10.1111/ene.15409
European Journal of Neurology; Shang ZY, Tao L et. al.

May 21st, 2022 - To investigate the characteristics of non-stenotic intracranial plaque (NSIP) among embolic stroke of undetermined source (ESUS) subtypes by high-resolution magnetic resonance imaging (HR-MRI). we retrospectively enrolled consecutive patients with ESUS who were mandatory for HR-MRI. Based the location and arterial supply of the infarct, ESUS were categorized into three types: cortical ESUS, sub...

Evaluation of Radiation Oncologist And Trainee Opinions on Residency Expansion, Possibl...
https://doi.org/10.1016/j.ijrobp.2022.05.005
International Journal of Radiation Oncology, Biology, Phy... Liu J, Chen YJ et. al.

May 21st, 2022 - To sample U.S. radiation oncologist and trainee opinions regarding residency expansion, what action(s) should be taken to limit residency supply, if any, and the proposed Accreditation Council for Graduate Medical Education (ACGME) changes. An online survey was distributed to 1048 attending radiation oncologists by email and ∼800 residents through their program coordinators. The survey asked re...