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About 314,593 results

What aerosol physics tells us about airborne pathogen transmission
https://www.tandfonline.com/doi/full/10.1080/02786826.2020.1751055

While a global pandemic by SARS-CoV in 2002–2003 was averted by fast identification, effective surveillance, and quarantine, such measures cannot be easily transferred to new situations, as the case of SARS-CoV-2 demonstrates. Knowledge of the fundamental biological and physical parameters affecting transmission pathways of respiratory pathogens is thus critical for the design of effective non-...

Lilly SARS-CoV-2 Assay - Letter of Authorization
https://www.fda.gov/media/140540/download
FDA

Qualitative detection of nucleic acid from SARS-CoV-2 in nasopharyngeal swabs, oropharyngeal (throat) swabs, anterior nasal swabs, mid-turbinate nasal swabs, nasal aspirates, nasal washes and bronchoalveolar lavage (BAL) fluid from individuals suspected of COVID-19 by their healthcare provider.

Risk factors of levodopa-induced dyskinesia in Parkinson’s disease: results from the PPMI cohort
https://www.nature.com/articles/s41531-018-0069-x
NPJ Parkinson's Disease;

Levodopa-induced dyskinesias (LID) negatively impact on the quality of life of patients with Parkinson’s disease (PD). We assessed the risk factors for LID in a cohort of de-novo PD patients enrolled in the Parkinson’s Progression Markers Initiative (PPMI). This retrospective cohort study included all PD patients enrolled in the PPMI cohort. Main outcome was the incidence rate of dyskinesia, de...

Can a toilet promote virus transmission? From a fluid dynamics perspective
https://aip.scitation.org/doi/10.1063/5.0013318

Currently, a novel coronavirus named “SARS-CoV-2” is spreading rapidly across the world, causing a public health crisis, economic losses, and panic. Fecal–oral transmission is a common transmission route for many viruses, including SARS-CoV-2. Blocking the path of fecal–oral transmission, which occurs commonly in toilet usage, is of fundamental importance in suppressing the spread of viruses. H...

Acute Respiratory Distress Syndrome: Diagnosis and Management
https://www.aafp.org/afp/2020/0615/p730.html
AAFP

Acute respiratory distress syndrome (ARDS) is noncardiogenic pulmonary edema that manifests as rapidly progressive dyspnea, tachypnea, and hypoxemia. Diagnostic criteria include onset within one week of a known insult or new or worsening respiratory symptoms, profound hypoxemia, bilateral pulmonary opacities on radiography, and inability to explain respiratory failure by cardiac failure or flui...

Negative Nasopharyngeal and Oropharyngeal Swabs Do Not Rule Out COVID-19
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180262/
Journal of Clinical Microbiology;

Coronavirus disease 19 (COVID-19) has become the Public Health Emergency of International Concern. A diagnosis is made by the detection of a novel virus or genetically similar coronavirus by molecular assay in clinical specimens (1). Nasopharyngeal and oropharyngeal (NP/OP) samples are commonly used as a screening tool. Here, we reported a case of COVID-19 pneumonia diagnosed from bronchoalveol...

Water and beverage consumption habits of adults in Turkey by gender and BMI: a cross-se...
https://doi.org/10.1080/09603123.2023.2172385
International Journal of Environmental Health Research; Pehlivan M, Saleki N et. al.

Feb 6th, 2023 - The study aims to determine water and beverage consumption status and related factors in daily nutrition of adults living in Turkey. This study was conducted with 6332 adults aged 18-65 years across Turkey. Demographics and anthropometric data of subjects, their daily water and beverage consumption habits were explored using the retrospective 24-hour recall method. Water and black tea were the ...

Recurrent meningitis caused by Salmonella enterica Paratyphi B var. Java in a 3-month-o...
https://doi.org/10.1080/20469047.2023.2168428
Paediatrics and International Child Health; Pavlova M, Lazarova GT et. al.

Feb 6th, 2023 - A 3-month-old female infant with meningo-encephalitis caused by Salmonella enterica Paratyphi B var. Java is described. The aetiological agent was confirmed in six CSF samples; however, none of the blood or faecal samples was positive for the same pathogen. The presence of the bacteria was confirmed in the CSF by culture, serology and Multiplex PCR assay. The infant developed dilated subarachno...

Gorham-Stout disease affecting the spine with cerebrospinal fluid leakage and Chiari-li...
https://doi.org/10.1186/s12883-023-03092-y
BMC Neurology; Xing QQ, Miao M et. al.

Feb 5th, 2023 - Gorham-Stout disease (GSD) is a very rare disorder characterized by massive osteolysis of poorly understood aetiology. The association between GSD involving the skull base and cerebrospinal fluid (CSF) leakage has been reported in the literature. However, few cases of CSF leakage and Chiari-like tonsillar herniation in GSD involving the spine have been reported. We present the case of a 20-year...

Small vessel childhood primary angiitis of the central nervous system with positive ant...
https://doi.org/10.1186/s12883-023-03093-x
BMC Neurology; Datyner E, Adeseye V et. al.

Feb 5th, 2023 - Small vessel childhood primary angiitis of the central nervous system (SV-cPACNS) is a rare disease characterized by inflammation within small vessels such as arterioles or capillaries. We report a case of SV-cPACNS in an 8-year-old boy confirmed by brain biopsy. This patient was also incidentally found to have anti-glial fibrillary acidic protein (GFAP) antibodies in the cerebrospinal fluid (C...

Effects and molecular mechanism of flagellar gene flgK on the motility, adhesion/invasi...
https://doi.org/10.1016/j.foodres.2022.112418
Food Research International (Ottawa, Ont.); Li P, Zong W et. al.

Feb 5th, 2023 - Cronobacter sakazakii (C. sakazakii), a food-borne pathogen, can infect neonates, elderly and immunocompromised populations with a high infection and mortality rate. However, the specific molecular mechanism of its motility, biofilm formation, cell adhesion, and desiccation resistance remains unclear, and flagellum hook associated protein (FlgK), a main component of the flagellar complex, may b...

Irigenin attenuates lipopolysaccharide-induced acute lung injury by inactivating the mi...
https://doi.org/10.1177/09603271231155098
Human & Experimental Toxicology; Liu D, Wang Q et. al.

Feb 5th, 2023 - Acute lung injury (ALI) is a serious pulmonary inflammation disease with high mortality. Irigenin, an isoflavone from rhizomes of the Belamcanda chinensis, has been reported to exert anti-inflammatory, anti-oxidative, and anti-apoptotic activities in several diseases. However, it is still unclear whether irigenin can exert a beneficial effect in ALI. A network pharmacology method was utilized t...

Chronic inflammatory demyelinating polyradiculoneuropathy: diagnostic problems in clini...
https://doi.org/10.1111/jns.12537
Journal of the Peripheral Nervous System : JPNS; Basta I, Delic N et. al.

Feb 5th, 2023 - Making diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is challenging since it can mimic a multitude of disorders, and is misdiagnosed in at least 50% of cases. We sought to determine the frequency of CIDP misdiagnosis in clinical practice in Serbia, to uncover CIDP mimics, and to identify factors that may aid in CIDP diagnosis. Our longitudinal retrospective cohor...

Triphasic response after endoscopic craniopharyngioma resection and its dependency on i...
https://doi.org/10.3171/2022.12.JNS221137
Journal of Neurosurgery; Lopez DC, Almeida JP et. al.

Feb 5th, 2023 - Surgery is the primary treatment for craniopharyngioma with the preservation of hypothalamic function of paramount importance. Infundibular preservation is debated, as maximal resection decreases recurrence rates but causes hypopituitarism. A triphasic response of diabetes insipidus (DI), syndrome of inappropriate antidiuretic hormone secretion (SIADH), and recurrent DI has been described after...

Incisional CSF leakage after intradural cranial surgery in children: incidence, risk fa...
https://doi.org/10.3171/2022.11.PEDS22421
Journal of Neurosurgery. Pediatrics; Slot EMH, van Doormaal TPC et. al.

Feb 5th, 2023 - The risk of cerebrospinal fluid (CSF) leakage after cranial surgery and its associated complications in children are unclear because of variable definitions and the lack of multicenter studies. In this study, the authors aimed to establish the incidence of CSF leakage after intradural cranial surgery in the pediatric population. In addition, they evaluated potential risk factors and complicatio...

Pachymeningitis associated with IgG4-related disease and ANCA positivity: Case report a...
https://doi.org/10.1016/j.autrev.2023.103285
Autoimmunity Reviews; Gautier F, Neumann L et. al.

Feb 5th, 2023 - Hypertrophic pachymeningitis is a rare clinical disorder involving localized or diffuse thickening of the dura mater. Considering pachymeningitis is in the clinical spectrum of both diseases, an overlap syndrome is discussed. We report a case of hypertrophic pachymeningitis revealed by headache and cranial nerve dysfunction, and coexistence of biopsy-proven IgG4-RD pachymeningitis and MPO-ANCA ...

Reduced bioaccessibility of TiO2 (E 171) during puree soup digestion in a gastrointesti...
https://doi.org/10.1016/j.foodres.2022.112189
Food Research International (Ottawa, Ont.); Baranowska-Wójcik E, Szwajgier D et. al.

Feb 5th, 2023 - E171 (TiO2- Ttitanium dioxide), a food colourant containing nano fractions, is one of the additives used e.g. in the food industry, whose consumption may have a negative impact on human health. In order to determine the ability of food products and intestinal lactic acid bacteria to interact with TiO2, we conducted in vitro "digestions" of a food matrix (meat/vegetable puree soup) using an adva...

Bioactivities and green advanced extraction technologies of ginger oleoresin extracts: ...
https://doi.org/10.1016/j.foodres.2022.112283
Food Research International (Ottawa, Ont.); Kamaruddin MSH, Chong GH et. al.

Feb 5th, 2023 - Zingiber officinale Roscoe is an excellent source of bioactive compounds, mainly gingerols and shogaols compounds, that associated with various bioactivities including antioxidant, anticancer, anti-inflammatory, antimicrobial, and antibiofilm. Zingiber officinale Roscoe found its application in the food, pharmaceutical, and cosmeceutical industries. The demand for a high quality of ginger oleor...

Producing mixed-soy protein adsorption layers on alginate microgels to controlled-relea...
https://doi.org/10.1016/j.foodres.2022.112319
Food Research International (Ottawa, Ont.); Jin H, Wang L et. al.

Feb 5th, 2023 - In this study, the effects of soy protein isolate (SPI) on the morphology, encapsulation efficiency, storage stability, swelling behavior, and in vitro digestion behavior of calcium alginate (CA) microgels were investigated. CA and calcium alginate-SPI (CAS) microgels with encapsulated β-carotene were prepared by extruding a mixture of alginate and SPI using a co-extrusion technique, followed b...

Formation and application of edible oleogels prepared by dispersing soy fiber particles...
https://doi.org/10.1016/j.foodres.2022.112369
Food Research International (Ottawa, Ont.); Li Y, Zhang C et. al.

Feb 5th, 2023 - Oleogels containing less saturated and trans-fats were considered as an ideal option to replace the solid fats in foods. In this research, oleogel was fabricated by dispersing soy fiber particles (SFP) in soy oil, and further it was used in bread preparation. Effect of the particle size, particle content and the second fluid content on the formation of oleogels were evaluated, based on the appe...