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Supporting Adults Bereaved Through COVID-19: A Rapid Review of the Impact of Previous Pandemics on Grief and Bereavement
https://www.sciencedirect.com/science/article/pii/S0885392420303882

The global COVID-19 pandemic is likely to have a major impact on the experience of death, dying, and bereavement. This study aimed to review and synthesize learning from previous literature focused on the impact on grief and bereavement during other infectious disease outbreaks. We conducted a rapid scoping review according to the principles of the Joanna Briggs Institute and analyzed qualitati...

AASA COVID-19 RECOVERY TASK FORCE GUIDELINES FOR REOPENING SCHOOLS: An Opportunity to Transform Public Education
http://aasacentral.org/wp-content/uploads/2020/06/AASA-COVID-19-Recovery-Task-Force-Guiding-Principals-and-Action-Steps-for-Reopening-Schools.pdf

AASA, The School Superintendents Association, is committed to supporting superintendents and other school district leaders throughout the country during this challenging and unprecedented time. The following report presents a synthesis of the Guidelines for Reopening Schools recommended by superintendents throughout the United States as part of an ongoing AASA task force. During meetings of...

Protein Distribution and Muscle-Related Outcomes: Does the Evidence Support the Concept?
https://www.mdpi.com/2072-6643/12/5/1441/htm

There is a shift in thinking about dietary protein requirements from daily requirements to individual meal requirements. Per meal, stimulation of muscle protein synthesis has a saturable dose relationship with the quantity of dietary protein consumed. Protein intake above the saturable dose does not further contribute to the synthetic response; the “excess” amino acids are predominantly oxidize...

AGA Clinical Practice Guidelines on the Role of Probiotics in the Management of Gastrointestinal Disorders
https://www.gastrojournal.org/article/S0016-5085(20)34729-6/pdf

This document presents the official recommendations of the American Gastroenterological Association (AGA) on the role of probiotics in the management of gastrointestinal disorders. The guideline was developed by the AGA Institute’s Clinical Guidelines Committee and approved by the AGA Governing Board. It is accompanied by a technical review that provides a detailed synthesis of the evidence ...

Copper: Fact Sheet for Health Professionals
https://ods.od.nih.gov/factsheets/Copper-HealthProfessional/
NIH

Copper, an essential mineral, is naturally present in some foods and is available as a dietary supplement. It is a cofactor for several enzymes (known as “cuproenzymes”) involved in energy production, iron metabolism, neuropeptide activation, connective tissue synthesis, and neurotransmitter synthesis [1-3]. One abundant cuproenzyme is ceruloplasmin (CP), which plays a role in iron metabolism a...

MraZ Transcriptionally Controls the Critical Level of FtsL Required for Focusing Z-Ring...
https://doi.org/10.1128/jb.00243-22
Journal of Bacteriology; White ML, Hough-Neidig A et. al.

Aug 10th, 2022 - The bacterial division and cell wall (dcw) cluster is a highly conserved region of the genome which encodes several essential cell division factors, including the central divisome protein FtsZ. Understanding the regulation of this region is key to our overall understanding of the division process. mraZ is found at the 5' end of the dcw cluster, and previous studies have described MraZ as a sequ...

Community-based models of health care for women, trans and nonbinary people released fr...
https://doi.org/10.1111/jocn.16464
Journal of Clinical Nursing; Paynter M, Heggie C et. al.

Aug 10th, 2022 - To illustrate the scope of different types of transitional, community-based health interventions for formerly incarcerated women, trans and nonbinary people, the eligibility criteria for these interventions, and associated health outcomes. Meeting the health needs of formerly incarcerated people in community, rather than through the criminal justice system, may prevent further experiences of cr...

Synthesis and Biological Evaluation of Steviol Derivatives with Improved Cytotoxic Acti...
https://doi.org/10.1021/acs.jnatprod.2c00161
Journal of Natural Products; Liu JS, Luo LP et. al.

Aug 10th, 2022 - Steviol is an ent-kaurene diterpenoid with interesting pharmacological activity. Several steviol derivatives with an exo-methylene cyclopentanone unit were discovered as potent antitumor agents. However, their poor selectivity for tumor cells relative to normal cells reduces their prospects as potential anticancer drugs. In this study, based on previous work, 32 steviol derivatives, including 2...

Vacatadithiasapphyrins: Synthesis, Structure, and Spectral and Redox Properties.
https://doi.org/10.1021/acs.joc.2c01088
The Journal of Organic Chemistry; Ali MA, Ravikanth M

Aug 10th, 2022 - Four examples of novel aromatic [22]vacatadithiasapphyrins were synthesized by refluxing appropriate [22]telluradithiasapphyrins in 1,2-dichlorobenzene in the presence of excess HCl followed by simple column chromatographic purification. The [22]vacatadithiasapphyrins can exist in three conformers "in", "out", and "zigzag" w.r.t the butadiene moiety, and under our experimental conditions, the "...

Synthetic growth by self-lubricated photopolymerization and extrusion inspired by plant...
https://doi.org/10.1073/pnas.2201776119
Proceedings of the National Academy of Sciences of the Un... Hausladen MM, Zhao B et. al.

Aug 10th, 2022 - Many natural organisms, such as fungal hyphae and plant roots, grow at their tips, enabling the generation of complex bodies composed of natural materials as well as dexterous movement and exploration. Tip growth presents an exemplary process by which materials synthesis and actuation are coupled, providing a blueprint for how growth could be realized in a synthetic system. Herein, we identify ...

Assessing the consistency of iPSC and animal models in cystic fibrosis modelling: A met...
https://doi.org/10.1371/journal.pone.0272091
PloS One; Darwish T, Al-Khulaifi A et. al.

Aug 10th, 2022 - Cystic fibrosis (CF) is a hereditary autosomal recessive disorder caused by a range of mutations in the CF Transmembrane Conductance Regulator (CFTR) gene. This gene encodes the CFTR protein, which acts as a chloride channel activated by cyclic AMP (cAMP). This meta-analysis aimed to compare the responsiveness of induced pluripotent stem cells (iPSCs) to cAMP analogues to that of commonly used ...

Monkeypox Treatment & Management
https://emedicine.medscape.com/article/1134714-treatment

Aug 10th, 2022 - Medical Care The disease is usually self-limited; resolution occurs in 2-4 weeks. In the African cases, the mortality rate was 1-10%, and death was related to the patients' health status and other comorbidities. Most patients died of secondary infections. No fatalities were reported in the 2003 US outbreak. Patients often feel poorly during the febrile stage of the illness; therefore, bedrest a...

Interventions for and experiences of shared decision-making underpinning reproductive h...
https://doi.org/10.1136/bmjopen-2022-062392
BMJ Open; Mc Laughlin L, Neukirchinger B et. al.

Aug 9th, 2022 - To determine intervention effects and synthesise qualitative research that explored women with or at high risk of kidney disease experiences of shared decision-making in relation to their reproductive health, family planning options and pregnancy. A systematic review of interventions and a qualitative evidence synthesis. We searched Cochrane, CINAHL, MEDLINE, Scopus, ProQuest, Elsevier, PubMed,...

Predictors of emotional distress in uveal melanoma survivors: a systematic review.
https://doi.org/10.1038/s41433-022-02193-1
Eye (London, England); Davies C, Brown SL et. al.

Aug 9th, 2022 - Uveal melanoma (UM) survivors can experience significant emotional distress, although the factors underpinning this are poorly understood. Systematic reviews of distress in UM only include cross-sectional studies, thereby limiting our understanding of causal factors. This review identified prospective clinical, demographic, social and psychological predictors of distress in UM survivors. A syst...

De novo transcriptome revealed genes involved in anthocyanin biosynthesis, transport, a...
https://doi.org/10.1186/s12864-022-08815-y
BMC Genomics; Li JL, Weng Z et. al.

Aug 9th, 2022 - Acer pseudosieboldianum is a kind of excellent color-leafed plants, and well known for its red leaves in autumn. At the same time, A. pseudosieboldianum is one of the native tree species in the northeast of China, and it plays an important role in improving the lack of color-leafed plants in the north. In previous study, we found a mutant of the A. pseudosieboldianum that leaves intersect red a...

Barriers and facilitators to HIV prevention interventions for reducing risky sexual beh...
https://doi.org/10.1186/s12879-022-07649-z
BMC Infectious Diseases; Mbengo F, Adama E et. al.

Aug 9th, 2022 - Interventions aimed at reducing risky sexual behavior are considered an important strategy for averting Human Immunodeficiency Virus (HIV) infection among youth (15-24 years) who continue to be at risk of the disease. Enhancing intervention success requires a comprehensive understanding of the barriers and facilitators to interventions targeting youth. However, there is lack of a systematic rev...

IgG4-Related Sclerosing Disease of the Temporal Bone: A Systematic Review.
https://doi.org/10.1097/MAO.0000000000003614
Otology & Neurotology : Official Publication of the Ameri... Oochit KK, Wong YY et. al.

Aug 9th, 2022 - IgG4-related disease (IgG4-RD) involving the temporal bone is an uncommon and underrecognized pathology often mistaken for malignancy. This systematic review is the first that aims to thoroughly analyze IgG4-RD of the temporal bone. Ovid MEDLINE, EMBASE, Cochrane Library, and Google Scholar. We used the following search keywords: "lgG4-RD," "skull," "skull base," "cranial," "temporal bone," "in...

Rh(III)-Catalyzed Tandem Reaction Access to (Quinazolin-2-yl)methanone Derivatives from...
https://doi.org/10.1021/acs.joc.2c01214
The Journal of Organic Chemistry; Liu S, Wang AJ et. al.

Aug 9th, 2022 - A Rh(III)-catalyzed tandem reaction for the synthesis of (quinazolin-2-yl)methanone derivatives has been explored from 2,1-benzisoxazoles and α-azido ketones. The transformation involves Rh(III)-catalyzed denitrogenation of α-azido ketones, aza-[4 + 2] cycloaddition, ring opening, and dehydration aromatization processes. Notably, the aza-[4 + 2] cycloaddition of an imine rhodium complex interme...

How applicable is geospatial analysis in maternal and neonatal health in sub-Saharan Af...
https://doi.org/10.7189/jogh.12.04066
Journal of Global Health; Alemu SM, Tura AK et. al.

Aug 9th, 2022 - Sub-Saharan Africa (SSA) has the world's highest maternal and neonatal morbidity and mortality and has shown the slowest progress in reducing them. In addition, there is substantial inequality in terms of maternal and neonatal morbidity and mortality in the region. Geospatial studies can help prioritize scarce resources by pinpointing priority areas for implementation. This systematic review wa...

Mechanisms of action of anti-inflammatory proteins and peptides with anti-TNF-alpha act...
https://doi.org/10.1371/journal.pone.0270749
PloS One; Lima MSR, de Lima VCO et. al.

Aug 9th, 2022 - Several studies in animal models of intestinal inflammation have been performed with the aim of understanding the mechanisms of action of anti-inflammatory proteins and peptides that reduce TNF-α. In order to present the best targets, effects and strategies for the treatment of intestinal inflammation in experimental models, this systematic review (SR) aimed to answer the following question: wh...