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About 285,423 results

Phylogenomic and functional characterization of an evolutionary conserved cytochrome P4...
https://doi.org/10.1073/pnas.2205850119
Proceedings of the National Academy of Sciences of the Un... Haas J, Hayward A et. al.

Jun 24th, 2022 - The regulatory process for assessing the risks of pesticides to bees relies heavily on the use of the honeybee, Apis mellifera, as a model for other bee species. However, the validity of using A. mellifera as a surrogate for other Apis and non-Apis bees in pesticide risk assessment has been questioned. Related to this line of research, recent work on A. mellifera has shown that specific P450 en...

Leafy and weedy seadragon genomes connect genic and repetitive DNA features to the extr...
https://doi.org/10.1073/pnas.2119602119
Proceedings of the National Academy of Sciences of the Un... Small CM, Healey HM et. al.

Jun 24th, 2022 - Seadragons are a remarkable lineage of teleost fishes in the family Syngnathidae, renowned for having evolved male pregnancy. Comprising three known species, seadragons are widely recognized and admired for their fantastical body forms and coloration, and their specific habitat requirements have made them flagship representatives for marine conservation and natural history interests. Until rece...

Bagaza Virus in Wild Birds, Portugal, 2021.
https://doi.org/10.3201/eid2807.212408
Emerging Infectious Diseases; Queirós J, Barros SC et. al.

Jun 23rd, 2022 - Bagaza virus emerged in Spain in 2010 and was not reported in other countries in Europe until 2021, when the virus was detected by molecular methods in a corn bunting and several red-legged partridges in Portugal. Sequencing revealed high similarity between the 2021 strains from Portugal and the 2010 strains from Spain.

High exposure of global tree diversity to human pressure.
https://doi.org/10.1073/pnas.2026733119
Proceedings of the National Academy of Sciences of the Un... Guo WY, Serra-Diaz JM et. al.

Jun 17th, 2022 - Safeguarding Earth's tree diversity is a conservation priority due to the importance of trees for biodiversity and ecosystem functions and services such as carbon sequestration. Here, we improve the foundation for effective conservation of global tree diversity by analyzing a recently developed database of tree species covering 46,752 species. We quantify range protection and anthropogenic pres...

Anti-bat ultrasound production in moths is globally and phylogenetically widespread.
https://doi.org/10.1073/pnas.2117485119
Proceedings of the National Academy of Sciences of the Un... Barber JR, Plotkin D et. al.

Jun 16th, 2022 - Warning signals are well known in the visual system, but rare in other modalities. Some moths produce ultrasonic sounds to warn bats of noxious taste or to mimic unpalatable models. Here, we report results from a long-term study across the globe, assaying moth response to playback of bat echolocation. We tested 252 genera, spanning most families of large-bodied moths, and document anti-bat ultr...

How months-long COVID infections could seed dangerous new variants.
https://doi.org/10.1038/d41586-022-01613-2 10.1038/s41467-022-30163-4 10.1126/scitranslmed.abh1803 10.1038/s41586-021-03291-y 10.1056/NEJMc2031364 10.7554/eLife.69091 10.1093/molbev/msac061 10.1038/s41586-022-04474-x 10.1093/ve/veab091 10.1038/s41467-022-29104-y 10.1016/S2666-5247(21)00030-6 10.1007/s10875-021-01158-5
Nature Callaway E

Jun 16th, 2022 - How months-long COVID infections could seed dangerous new variants.|2022|Callaway E,|virology,classification,genetics,

The source of the Black Death in fourteenth-century central Eurasia.
https://doi.org/10.1038/s41586-022-04800-3 10.1162/jinh_a_01376 10.1038/nature10549 10.1017/S0022050717000092 10.1017/S1361491607002031 10.1073/pnas.1205750110 10.1038/s41467-019-12154-0 10.1371/journal.pone.0187230 10.3389/fmicb.2018.01106 10.1073/pnas.2009677117 10.1073/pnas.1812865115 10.17302/TMG.1-1.11 10.1163/18747167-12341321 10.1093/ahr/rhaa511 10.1038/nature14558 10.1186/s13059-019-1903-0 10.1073/pnas.1820447116 10.1146/annurev-genom-091416-035526 10.7554/eLife.12994 10.1016/S2666-5247(20)30176-2 10.1038/s41467-018-04550-9 10.1093/ve/vex042 10.1038/ng.705 10.1101/gr.251678.119 10.1016/j.celrep.2021.109278 10.1038/s41586-018-0094-2 10.1128/CMR.17.2.434-464.2004 10.1038/s41576-019-0119-1 10.1017/mdh.2021.3 10.1162/002219503322645439 10.4178/epih/e2015050 10.1073/pnas.1412887112 10.1086/711596 10.1038/srep43467 10.1101/gr.232397.117 10.1073/pnas.1314445110 10.1101/pdb.prot5448 10.1098/rstb.2013.0624 10.1093/nar/gkr771 10.1186/s13104-016-1900-2 10.1093/nar/gkv1189 10.1038/s41559-017-0446-6 10.1093/bioinformatics/btp352 10.1093/bioinformatics/btt193 10.1038/s41596-020-0338-0 10.1016/j.cub.2017.10.025 10.1038/nature16152 10.1073/pnas.1221359110 10.1038/nature14317 10.1186/s13059-016-0918-z 10.1073/pnas.1105107108 10.1371/journal.pcbi.1004957 10.1038/ng.806 10.1038/nature13591 10.1093/molbev/msw170 10.1128/genomeA.00847-17 10.1128/JB.186.15.5147-5152.2004 10.1093/bioinformatics/btu033 10.1093/bioinformatics/btq166 10.1016/0006-3207(92)91201-3 10.18637/jss.v053.i09 10.1093/molbev/msw054 10.1371/journal.pcbi.1006650 10.1093/molbev/msi103 10.1126/science.aaw8977 10.1038/s41598-020-66012-x 10.1126/science.abi5658 10.1038/s41559-020-1106-9 10.1186/s13059-020-02112-1 10.1073/pnas.1207965110 10.1038/nmeth.2109 10.1007/s11357-008-9053-4 10.1111/1749-4877.12511 10.1073/pnas.1715640115 10.1080/01621459.1995.10476572 10.1093/ve/vew007 10.1093/molbev/msaa163
Nature Spyrou MA, Musralina L et. al.

Jun 16th, 2022 - The origin of the medieval Black Death pandemic (AD 1346-1353) has been a topic of continuous investigation because of the pandemic's extensive demographic impact and long-lasting consequences1,2. Until now, the most debated archaeological evidence potentially associated with the pandemic's initiation derives from cemeteries located near Lake Issyk-Kul of modern-day Kyrgyzstan1,3-9. These sites...

Host protease activity classifies pneumonia etiology.
https://doi.org/10.1073/pnas.2121778119
Proceedings of the National Academy of Sciences of the Un... Anahtar M, Chan LW et. al.

Jun 14th, 2022 - Community-acquired pneumonia (CAP) has been brought to the forefront of global health priorities due to the COVID-19 pandemic. However, classification of viral versus bacterial pneumonia etiology remains a significant clinical challenge. To this end, we have engineered a panel of activity-based nanosensors that detect the dysregulated activity of pulmonary host proteases implicated in the respo...

Geological activity shapes the microbiome in deep-subsurface aquifers by advection.
https://doi.org/10.1073/pnas.2113985119
Proceedings of the National Academy of Sciences of the Un... Zhang Y, Horne RN et. al.

Jun 14th, 2022 - Subsurface environments host diverse microorganisms in fluid-filled fractures; however, little is known about how geological and hydrological processes shape the subterranean biosphere. Here, we sampled three flowing boreholes weekly for 10 mo in a 1478-m-deep fractured rock aquifer to study the role of fracture activity (defined as seismically or aseismically induced fracture aperture change) ...

Mineral Elements and Vitamins from Wild Wood Inhabiting Basidiocarps of Some Medicinal ...
https://doi.org/10.1615/IntJMedMushrooms.2022043411
International Journal of Medicinal Mushrooms; Azeem U, Shri R et. al.

Jun 14th, 2022 - Mushrooms are rich in various nutrients and secondary metabolites. In this study, the contents of macroelements, trace elements, and some nonessential elements of wild basidiocarps of Fuscoporia torulosa, Inonotus pachyphloeus, Phellinus allardii, Ph. fastuosus, Ph. gilvus, and Ph. sanfordii (Hymenochaetaceae) collected from India was determined with wavelength dispersive X-ray fluorescence spe...

Accurate virus identification with interpretable Raman signatures by machine learning.
https://doi.org/10.1073/pnas.2118836119
Proceedings of the National Academy of Sciences of the Un... Ye J, Yeh YT et. al.

Jun 3rd, 2022 - Significance A large Raman dataset collected on a variety of viruses enables the training of machine learning (ML) models capable of highly accurate and sensitive virus identification. The trained ML models can then be integrated with a portable device to provide real-time virus detection and identification capability. We validate this conceptual framework by presenting highly accurate virus ty...

Evaluation of rain-shelter cultivation mode effects on microbial diversity during Caber...
https://doi.org/10.1016/j.foodres.2022.111165
Food Research International (Ottawa, Ont.); Huang R, Shen L et. al.

Jun 3rd, 2022 - Rainfall particularly under continental climates with monsoonal tendency impacts the vineyard microbial niches during grapevine growth. With microbial community shifts, vine traits (grape flavor and yield) cultivated/protected under rain-shelter may ultimately be altered. Such cultivation may influence microflora dynamics via meteorological parameter variations, however this is unclear yet. Her...

Morphology of Palaeospondylus shows affinity to tetrapod ancestors.
https://doi.org/10.1038/s41586-022-04781-3 10.1080/00222939008694071 10.1038/381061a0 10.1017/S0263593300010737 10.1098/rstb.1904.0009 10.18195/issn.0312-3162.23(1).2006.091-113 10.1098/rsos.170214 10.1098/rspb.2015.2917 10.1002/jez.b.21441 10.1111/j.1096-0031.1991.tb00045.x 10.1098/rstb.1940.0004 10.1038/s41586-018-0782-y 10.1038/s41586-019-1117-3 10.1080/02724634.2012.679588 10.1038/s41586-020-2100-8 10.1093/sysbio/sys029 10.1017/S0263593300006787 10.1080/02724634.1984.10011982 10.1016/j.semcdb.2009.11.004 10.1111/j.1463-6395.2010.00456.x 10.1038/nature19354 10.1038/nature08623 10.1063/1.3478197 10.1038/nmeth.2019 10.1117/12.935640 10.3389/fevo.2021.679633
Nature Hirasawa T, Hu Y et. al.

May 26th, 2022 - Palaeospondylus gunni, from the Middle Devonian period, is one of the most enigmatic fossil vertebrates, and its phylogenetic position has remained unclear since its discovery in Scotland in 1890 (ref. 1). The fossil's strange set of morphological features has made comparisons with known vertebrate morphotype diversity difficult. Here we use synchrotron radiation X-ray micro-computed tomography...

Adolescent perspectives on participating in a feasibility trial investigating shoe inse...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109440
Journal of Foot and Ankle Research; O'Sullivan IC, da Costa NC et. al.

May 17th, 2022 - Patellofemoral pain (PFP) affects one-quarter of adolescents, yet there are few evidence-informed recommendations to treat PFP in this population. HAPPi Kneecaps! is a randomised, controlled, participant- and assessor-blind, parallel-group feasibility trial of shoe inserts for adolescents with PFP. The aim of this qualitative study was to explore adolescents' perspectives of participating in HA...

The Genetic Population Structure of Lake Tanganyika's Lates Species Flock, an Endemic R...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113442
The Journal of Heredity; Rick JA, Junker J et. al.

May 17th, 2022 - Understanding genetic connectivity plays a crucial role in species conservation decisions, and genetic connectivity is an important component of modern fisheries management. In this study, we investigated the population genetics of four endemic Lates species of Lake Tanganyika (Lates stappersii, L. microlepis, L. mariae, and L. angustifrons) using reduced-representation genomic sequencing metho...

Diversity and Long-Term Dynamics of Human Blood Anelloviruses.
https://doi.org/10.1128/jvi.00109-22
Journal of Virology; Kaczorowska J, Deijs M et. al.

May 17th, 2022 - Anelloviruses (AVs) are commensal members of the human blood virome. Even though it was estimated that over 90% of the human population carries AVs, the dynamics of the AV virome ("anellome") are unknown. We investigated the dynamics of blood anellomes in two healthy people followed up for more than 30 years. Both subjects were positive for AVs in the majority of samples. Alphatorquevirus (torq...

Predicting acute kidney injury following open partial nephrectomy treatment using SAT-p...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112450
BMC Medical Informatics and Decision Making; Lazebnik T, Bahouth Z et. al.

May 17th, 2022 - One of the most prevalent complications of Partial Nephrectomy (PN) is Acute Kidney Injury (AKI), which could have a negative impact on subsequent renal function and occurs in up to 24.3% of patients undergoing PN. The aim of this study was to predict the occurrence of AKI following PN using preoperative parameters by applying machine learning algorithms. We included all adult patients (n = 723...

A global reptile assessment highlights shared conservation needs of tetrapods.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095493
Nature Cox N, Young BE et. al.

Apr 29th, 2022 - Comprehensive assessments of species' extinction risks have documented the extinction crisis1 and underpinned strategies for reducing those risks2. Global assessments reveal that, among tetrapods, 40.7% of amphibians, 25.4% of mammals and 13.6% of birds are threatened with extinction3. Because global assessments have been lacking, reptiles have been omitted from conservation-prioritization anal...

Evidence of pediatric sepsis caused by a drug resistant Lactococcus garvieae contaminat...
https://doi.org/10.1080/22221751.2022.2071174
Emerging Microbes & Infections; Colagrossi L, Costabile V et. al.

Apr 28th, 2022 - Owing to an increasing number of infections in adults, Lactococcus (L.) garvieae has gained recognition as an emerging human pathogen, causing bacteraemia and septicaemia. In September 2020, four paediatric onco-hematologic patients received a platelet concentrate from the same adult donor at Bambino Gesù Children's Hospital IRCCS, Rome. Three of four patients experienced L. garvieae sepsis one...

Baseline factors associated with self-reported disease flares following COVID-19 vaccin...
https://doi.org/10.1093/rheumatology/keac249
Rheumatology (Oxford, England); Rider LG, Parks CG et. al.

Apr 24th, 2022 - To examine the frequency of, and risk factors for, disease flare following COVID-19 vaccination in patients with systemic rheumatic disease (SRD). An international study was conducted from 2 April to 16 August 2021, using an online survey of 5619 adults with SRD for adverse events following COVID-19 vaccination, including flares of disease requiring a change in treatment. We examined risk facto...