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About 275,665 results

Multi-intervention integrated deworming strategy for sustained control of soil-transmit...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434715
Infectious Diseases of Poverty; Mao FZ, Chen YY et. al.

Sep 12th, 2021 - Soil-transmitted helminths (STH) infections still present a global health problem. Mass drug administration (MDA) is a widely applied strategy to reduce morbidity and mortality caused by STH. Yet, this approach has some shortcomings. In this study, we analyzed the impact of a multi-intervention integrated deworming approach including MDA, health education (HE), and environmental sanitation impr...

Characteristics and mortality in primary Sjögren syndrome-related interstitial lung dis...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415932
Medicine Gao H, Sun Y et. al.

Sep 4th, 2021 - Aim of the study was to determine the characteristics and prognosis, and to identify the risk factors for mortality in patients with primary Sjögren syndrome (pSS) with interstitial lung disease (pSS-ILD).A total of 1422 patients with SS were screened and 178 patients with pSS-ILD were recruited. The medical records and outcomes were retrospectively reviewed. Overall survival and case control s...

Identification of the similarly expressed genes in patients with polycystic ovary syndr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415929
Medicine Dong R, Gao S et. al.

Sep 4th, 2021 - Polycystic ovary syndrome (PCOS) is a common female infertility, which may be caused by excessive androgen, but its mechanism remains unknown. Transsexuals are women who take androgen drugs for a long time, and gradually have male signs. Their ovaries may have received high concentrations of androgen, which leads to the failure of ovarian reproductive function. Therefore, we searched the releva...

Clinical characteristics of cirrhosis patients with umbilical vein recanalization: A re...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415999
Medicine Shi Q, Xiong K et. al.

Sep 4th, 2021 - Umbilical Vein Recanalization (UVR) may occur in patients with long-standing portal hypertension and liver cirrhosis. This study aimed to investigate the clinical significance of UVR.Medical records of a cohort of patients with cirrhosis (n = 247) who were hospitalized at the Digestive Medicine Center of the Second Affiliated Hospital of Nanchang University from January 2012 to October 2015 wer...

To evaluate the microcirculation of retinochoroid capillary between acute and chronic c...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415977
Medicine Lu H, Wang Z et. al.

Sep 4th, 2021 - To investigate the difference in chorioretinal microcirculation between acute central serous chorioretinopathy (aCSC) and chronic central serous chorioretinopathy (cCSC) using optical coherence tomography angiography.In total, 65 patients previously diagnosed with central serous chorioretinopathy (33 aCSC and 32 cCSC) were included in our cross-sectional study. All patients underwent complete o...

Value of shear wave elastography combined with the Toronto clinical scoring system in d...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415960
Medicine Wang F, Zheng M et. al.

Sep 4th, 2021 - To evaluate the diagnostic values of shear wave elastography (SWE) alone and in combination with the Toronto clinical scoring system (TCSS) on diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus (T2DM).The study included 41 DPN patients, 42 non-DPN patients, and 21 healthy volunteers. Conventional ultrasonography and SWE were performed on the 2 sides of the tibial ner...

Prevalence of musculoskeletal injury and pain of UK-based podiatrists and the impact of...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409074
Journal of Foot and Ankle Research; Adams R, Branthwaite H et. al.

Sep 3rd, 2021 - Occupational musculoskeletal injuries are prevalent in healthcare workers and are reported to be profession-specific. There is, however, a paucity of information around the injuries sustained from working as a podiatrist. This paper looks at the incidence of injury from working as a podiatrist, the aggravating factors to sustain these injuries and whether the changes in workload due to the COVI...

Origin of imported SARS-CoV-2 strains in The Gambia identified from whole genome sequen...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407536
PloS One; Kanteh A, Manneh J et. al.

Sep 1st, 2021 - The SARS-CoV-2 disease, first detected in Wuhan, China, in December 2019 has become a global pandemic and is causing an unprecedented burden on health care systems and the economy globally. While the travel history of index cases may suggest the origin of infection, phylogenetic analysis of isolated strains from these cases and contacts will increase the understanding and link between local tra...

Higher entropy observed in SARS-CoV-2 genomes from the first COVID-19 wave in Pakistan.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407562
PloS One; Ghanchi NK, Nasir A et. al.

Sep 1st, 2021 - We investigated the genome diversity of SARS-CoV-2 associated with the early COVID-19 period to investigate evolution of the virus in Pakistan. We studied ninety SARS-CoV-2 strains isolated between March and October 2020. Whole genome sequences from our laboratory and available genomes were used to investigate phylogeny, genetic variantion and mutation rates of SARS-CoV-2 strains in Pakistan. S...

The clinical outcomes of mechanical thrombectomy for proximal M1 occlusion involving le...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389878
Medicine Ko HC

Aug 28th, 2021 - Although the success rate of recanalization in acute intracranial artery occlusion is high, there is a poor rate of improvement in functional clinical outcome. The purpose of this study was to assess the functional outcome of mechanical thrombectomy for proximal M1 occlusion involving lenticulostriate arteries (LSAs) compared with distal M1 occlusion-sparing the LSAs.A retrospective analysis wa...

Biology and applications of co-produced, synergistic antimicrobials from environmental ...
https://doi.org/10.1038/s41564-021-00952-6 10.1039/C7NP00019G 10.1021/cb200337h 10.1093/femsre/fux005 10.1007/s10295-015-1686-6 10.1073/pnas.1934677100 10.1128/AEM.02863-07 10.1016/j.chembiol.2015.03.010 10.1016/j.cell.2014.06.034 10.1007/s10295-016-1815-x 10.1128/mBio.00416-20 10.1016/j.tig.2010.07.001 10.1073/pnas.0709132105 10.1046/j.1365-2958.2000.02098.x 10.1016/j.ijmm.2013.08.008 10.1128/mr.43.2.145-192.1979 10.1080/14787210.2021.1834851 10.1186/1741-7007-2-4 10.1111/j.1751-7915.2010.00213.x 10.1016/j.gene.2006.12.035 10.1046/j.1365-2958.2000.01819.x 10.1046/j.1365-2958.2003.03523.x 10.1073/pnas.0914100107 10.1073/pnas.1019406108 10.1128/JB.01383-07 10.1074/jbc.RA118.005314 10.1146/annurev-micro-022618-042458 10.7164/antibiotics.35.1400 10.1016/S0021-9258(19)88662-3 10.1021/acsinfecdis.8b00105 10.1021/acschembio.7b00687 10.1016/j.chembiol.2017.08.024 10.1038/s41467-018-03447-x 10.1021/jacs.8b02283 10.1073/pnas.0806261105 10.1007/978-1-4939-2398-4_4 10.1111/j.1365-2958.2006.05223.x 10.1039/C2NP20085F 10.1021/bi0362065 10.1046/j.1365-2958.1996.831449.x 10.1021/ja206281k 10.1073/pnas.0913554107 10.3389/fmicb.2017.00696 10.1007/s12602-009-9021-z 10.1016/S1367-5931(99)00025-3 10.1016/S0300-9084(02)01414-1 10.1016/j.bmc.2018.03.022 10.7164/antibiotics.45.1451 10.3389/fmicb.2020.578878 10.1146/annurev-micro-090816-093420 10.1128/AAC.11.5.852 10.1023/A:1001755724055 10.1186/1471-2164-15-970 10.1007/s10295-012-1191-0 10.7164/antibiotics.30.770 10.7164/antibiotics.32.295 10.1002/cbic.201300319 10.1016/j.chembiol.2016.12.012 10.1016/j.chembiol.2017.09.001 10.1016/j.jmb.2019.06.033 10.1038/nchembio.2376 10.1073/pnas.1721790115 10.1073/pnas.1510432112 10.1038/s41467-018-02875-z 10.1016/S0014-827X(01)01002-3 10.1038/s41598-020-64756-0 10.1073/pnas.0911237107 10.1038/srep40294 10.1074/jbc.H118.006669 10.1093/nar/gkz310 10.1038/nchembio0707-353 10.1073/pnas.0914343107 10.1038/srep14720 10.1186/s12864-020-06785-7 10.1016/j.chembiol.2015.11.014 10.1021/jacs.8b09328 10.3390/md13116910 10.1038/s41579-018-0141-x 10.1128/CMR.00037-09 10.1039/C9NP00011A 10.1038/nbt.3597 10.1039/C9NP00025A 10.1038/s41579-018-0075-3
Nature Microbiology; Meyer KJ, Nodwell JR

Aug 28th, 2021 - Environmental bacteria, such as Streptomyces spp., produce specialized metabolites that are potent antibiotics and therapeutics. Selected specialized antimicrobials are co-produced and function together synergistically. Co-produced antimicrobials comprise multiple chemical classes and are produced by a wide variety of bacteria in different environmental niches, suggesting that their combined fu...

Development of the Pulmonary Hypertension Functional Classification Self-Report: a pati...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386063
Health and Quality of Life Outcomes; Highland KB, Crawford R et. al.

Aug 26th, 2021 - Pulmonary arterial hypertension (PAH) is characterized by progressive limitations on physical activity, right heart failure, and premature death. The World Health Organization functional classification (WHO-FC) is a clinician-rated assessment used widely to assess PAH severity and functioning, but no equivalent patient-reported version of PAH symptoms and activity limitations exists. We develop...

Prognostic role of NK cell percentages in bronchoalveolar lavage from patients with dif...
https://doi.org/10.1016/j.clim.2021.108827
Clinical Immunology (Orlando, Fla.); Bergantini L, d'Alessandro M et. al.

Aug 25th, 2021 - BAL cellularity and lymphocyte immunophenotyping offer insights into lung inflammatory status. Natural killer (NK) cells are efficient effector cells, producing pro-inflammatory cytokines. A better understanding of the biology of NK cells in BAL in the lungs is necessary to improve the pathogenesis of fibrotic ILD and develop prospective targeted treatments. Our aim was to analyse NK and NKT-li...

Mapping of endometriosis in patients with unilateral endometrioma.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376365
Medicine Araujo RSDC, Maia SB et. al.

Aug 21st, 2021 - To map the distribution of the sites most affected by endometriosis in patients with unilateral ovarian endometriomas.A descriptive case series of 84 patients with unilateral endometriomas undergoing laparoscopy for the treatment of endometriosis. To evaluate the distribution of the sites of endometriosis lesions, the peritoneal compartments were divided into 5 zones: zone 1/the anterior compar...

Estimation of pulmonary artery pressure with transesophageal echocardiography: An obser...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376331
Medicine Mora B, Roth D et. al.

Aug 21st, 2021 - With the declining use of the pulmonary artery catheter (PAC), transesophageal echocardiography (TEE) has become an appealing alternative to obtain pulmonary artery pressure non-invasively using the simplified Bernoulli equation. The validation of this method in the perioperative setting has been scarce with no clear recommendations about which view is the most accurate to estimate right ventri...

Etiological and epidemiological features of acute respiratory infections in China.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373954
Nature Communications; Li ZJ, Zhang HY et. al.

Aug 20th, 2021 - Nationwide prospective surveillance of all-age patients with acute respiratory infections was conducted in China between 2009‒2019. Here we report the etiological and epidemiological features of the 231,107 eligible patients enrolled in this analysis. Children <5 years old and school-age children have the highest viral positivity rate (46.9%) and bacterial positivity rate (30.9%). Influenza vir...

Phylogenomics of a new fungal phylum reveals multiple waves of reductive evolution acro...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371127
Nature Communications; Galindo LJ, López-García P et. al.

Aug 19th, 2021 - Compared to multicellular fungi and unicellular yeasts, unicellular fungi with free-living flagellated stages (zoospores) remain poorly known and their phylogenetic position is often unresolved. Recently, rRNA gene phylogenetic analyses of two atypical parasitic fungi with amoeboid zoospores and long kinetosomes, the sanchytrids Amoeboradix gromovi and Sanchytrium tribonematis, showed that they...

Meniscal Injuries: Mechanism and Classification.
https://doi.org/10.1097/JSA.0000000000000311 10.1097/RMR.0b013e3181d657d1 10.1177/2325967119827945 10.1177/2325967119860806 10.1053/jars.2003.50067
Sports Medicine and Arthroscopy Review; Wells ME, Scanaliato JP et. al.

Aug 17th, 2021 - Meniscal tears may be managed through conservative physical therapy and nonsteroidal anti-inflammatory medications or operative intervention. Meniscal repair is superior to partial meniscectomy with better functional outcomes and less severe degenerative changes over time. Surgical advances in operative techniques, modern instrumentation and biological enhancements collectively improve healing ...

The effects of Baduanjin exercise on the subjective memory complaint of older adults: A...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322475
Medicine Su H, Wang H et. al.

Aug 17th, 2021 - This study aimed to explore the efficacy of Baduanjin exercise on promoting memory function, executive function and general self-efficacy, decreasing the level of subjective memory complaints of older adults.In this randomized controlled trial, 80 patients were randomly allocated in a 1:1 ratio to 12-week Baduanjin exercise group or 12-week control group. Subjective memory complaint questionnai...

Sensitive Immunodetection of Severe Acute Respiratory Syndrome Coronavirus 2 Variants o...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194863
The Journal of Infectious Diseases; Barlev-Gross M, Weiss S et. al.

Aug 17th, 2021 - Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants may influence the effectiveness of existing laboratory diagnostics. In the current study we determined whether the British (20I/501Y.V1) and South African (20H/501Y.V2) SARS-CoV-2 variants of concern are detected with an in-house S1-based antigen detection assay, analyzing spiked pools of quantitative reverse-transcr...