About 347,053 results

Risk of incident type 2 diabetes among patients with rheumatoid arthritis: a population‐based cohort study
Arthritis Care & Research; Jin Y

Aug 3rd, 2020 - We examined risk of incident type 2 diabetes mellitus (T2DM) among RA patients versus four different comparison cohorts.

Cinammon (Cinnamomum Spp.) and Type 2 Diabetes Mellitus

Spices such as cinnamon (Cinnamomum Spp.) have been of interest due to their phytochemical composition that exert hypoglycemic effects with potential for management of type 2 diabetes mellitus (T2DM). We summarize data from 27 manuscripts that include, one book chapter, 3 review articles, 10 randomized controlled trials, 4 systematic reviews with meta-analysis, and 9 preclinical studies. The...

Pros and cons for use of statins in people with coronavirus disease-19 (COVID-19)

Morbidity and mortality from coronavirus disease 2019 (COVID-19) is higher among people with diabetes mellitus (DM), hypertension, and cardiovascular disease (CVD). Statins are used in the majority of people with DM and CVD. This mini-review discusses the current understanding of benefit-risk ratio of use of statins in COVID-19.

Daily improvement of glucose variability by Continuous Glucose Monitoring (CGM)

Continuous Glucose Monitoring (CGM) has been recently applied in the clinical diabetic practice. Authors have continued research of glucose variability. In this study, 51 year-old female patient with Type 1 diabetes mellitus (T1DM) was investigated. She has given multiple daily insulin injection (MDI) for long and her recent daily glucose profile was unstable. After applied with FreeStyle Libre...

Weight loss induced by whole grain-rich diet is through a gut microbiota-independent mechanism

The prevalence of overweight and obesity has increased worldwide. Obesity is a well-known risk factor of type 2 diabetes mellitus and cardiovascular disease and raises public health concerns. Many dietary guidelines encourage the replacement of refined grains with whole grains (WGs) to enhance body weight management. Current evidence regarding interrelationships among WGs, body weight, and gut ...

Health Maintenance in Women

The health maintenance examination is an opportunity to focus on disease prevention and health promotion. The patient history should include screening for tobacco use, alcohol misuse, intimate partner violence, and depression. Premenopausal women should receive preconception counseling and contraception as needed, and all women planning or capable of pregnancy should take 400 to 800 mcg of foli...

Why the Stress-Disease Connection Matters and How to Respond

Family physicians are experts in caring for patients with chronic diseases and recognizing how stress impacts health. These skills naturally complement one another, as attested by research into the connection between chronic disease and stress. Stressors often include adverse childhood experiences, which are traumatic events or chronic stressors experienced in childhood, such as physical or sex...

Continuous Glucose Monitoring in Type 2 Diabetes Is Not Ready for Widespread Adoption

There is great interest in technology to improve health; however, new devices do not always live up to the hype. Although continuous glucose monitoring may benefit patients with type 1 diabetes mellitus, there is limited evidence that it offers similar benefits in patients with type 2 diabetes, regardless of whether they are taking insulin.

Screening for Prediabetes and Type 2 Diabetes in Children and Adolescents
JAMA US Preventative Services Task Force (USPSTF)

Sep 13th, 2022 - Importance The Centers for Disease Control and Prevention estimates that 210 000 children and adolescents younger than 20 years had diabetes as of 2018; of these, approximately 23 000 had type 2 diabetes. Youth with type 2 diabetes have an increased prevalence of associated chronic comorbid conditions, including hypertension, dyslipidemia, and nonalcoholic fatty liver disease. Data indicate th...

Diabetes Drug Metformin Shows Potential Benefit in Large COVID-19 Trial
Northwestern Medicine News Center; Samuelson K.

Aug 19th, 2022 - Metformin, a common, safe and inexpensive drug for type 2 diabetes, lowers the odds of emergency department visits, hospitalizations or death due to COVID-19 by over 40 percent; and over 50 percent if prescribed early in onset of symptoms, according to a new multi-site clinical trial published in the New England Journal of Medicine, led by the University of Minnesota Medical School and School o...

Screening of Hyperlipidemia Among Patients With Rheumatoid Arthritis in the United States
Arthritis Care & Research;

To determine the proportion of primary lipid screening among patients with rheumatoid arthritis (RA) and compare it with those among patients with diabetes mellitus (DM) and patients with neither RA nor DM, and to assess whether primary lipid screening varied according to the health care provider (rheumatologist versus non‐rheumatologist).

Protection by metformin against severe Covid-19: An in-depth mechanistic analysis
Diabetes & Metabolism; Wiernsperger N, Al-Salameh A et. al.

Jul 4th, 2022 - Since the outbreak of Covid-19, several observational studies on diabetes and Covid-19 have reported a favourable association between metformin and Covid-19-related outcomes in patients with type 2 diabetes mellitus (T2DM). This is not surprising since metformin affects many of the pathophysiological mechanisms implicated in SARS-CoV-2 immune response, systemic spread and sequelae.

Could the development of COVID-19 vaccine-induced type 1 diabetes be explained by a simple mechanism?
Diabetes & Metabolism; Sasaki H, Itoh A et. al.

Jul 3rd, 2022 - To the Editor We read with great interest the article “Fulminant type 1 diabetes (T1DM) after Covid-19 vaccination” by Tang et al. in this journal [1]. The authors examined islet autoantibodies, HLA alleles, and the capacity for insulin secretion specifically after the treatment of a 50-year-old patient who developed diabetic ketoacidosis following Covid-19 vaccination.

Pediatric Diabetes; Mastromauro C, Polidori N et. al.

Oct 3rd, 2022 - Fluid and insulin treatments are the cornerstones of DKA management and indications on dosages are available. However, according to possible confounding factors, relevant data are still required to explain the different insulin dosages adopted at diabetes onset, particularly based upon insulin sensitivity. We aimed to explore whether DKA severity is related to different insulin sensitivity stat...

Selective Serotonin Reuptake Inhibitors (SSRIs) in Pregnancy: An Updated Review on Risk...
Current Psychiatry Reports; Lebin LG, Novick AM

Oct 2nd, 2022 - To provide an updated summary and appraisal of work from 2019 to 2022 examining risks of selective serotonin reuptake inhibitor (SSRI) use in pregnancy. Perinatal SSRI exposure does not increase risk of major malformations or gestational diabetes after accounting for underlying maternal illness. SSRIs are associated with small increase in risk of pre-eclampsia, postpartum hemorrhage, preterm de...

The longitudinal loss of islet autoantibody responses from diagnosis of type 1 diabetes...
Clinical and Experimental Immunology; Williams CL, Fareed R et. al.

Oct 2nd, 2022 - The clinical usefulness of post-diagnosis islet autoantibody levels is unclear and factors that drive autoantibody persistence are poorly defined in type 1 diabetes (T1D). Our aim was to characterise longitudinal loss of islet autoantibody responses after diagnosis in a large, prospectively sampled UK cohort. Participants with T1D [n=577] providing a diagnosis sample [range -1.0-2.0 years] and ...

Early pregnancy glycaemia predicts postpartum diabetes mellitus.
European Journal of Obstetrics, Gynecology, and Reproduct... Callinan CE, Rockhill K et. al.

Oct 2nd, 2022 - To determine the association between early pregnancy glycaemia, as measured by glycosylated haemoglobin A1c (HbA1c) at the first prenatal visit, and persistent postpartum diabetes mellitus (DM). All women first diagnosed with DM during pregnancy who had both HbA1c prior to 24 weeks and postpartum DM testing were included. The proportions of women with normal (<5.7%), prediabetic (5.7-6.4%) and ...

Risk of obstetric and neonatal morbidity in gestational diabetes in a single institutio...
Medicine Chung YS, Moon H et. al.

Oct 2nd, 2022 - Gestational diabetes mellitus (GDM) is defined as a carbohydrate intolerance with onset or first recognition occurring during pregnancy and GDM could be risk factor for various maternal fetal complications. This study aimed to investigate risks of maternal and neonatal outcomes according to GDM and normal glucose tolerance. This retrospective, observational study included singleton pregnant wom...

Plasma and vitreous selenium concentrations in patients with type 2 diabetes and diabet...
Medicine Wang C, Ran R et. al.

Oct 2nd, 2022 - This work aimed to determine and compare plasma and vitreous selenium (Se) concentrations in patients with type 2 diabetes and diabetic retinopathy (DR). A total of 60 type-2-diabetes patients including 20 without DR, 20 with non-proliferative DR (NPDR), and 20 with proliferative diabetic retinopathy (PDR), were involved in this study. Blood plasma samples were collected from above 60 patients ...

Prevalence and risk factors of depression, anxiety, and stress in an Ecuadorian outpati...
Medicine Cárdenas L, Cabezas MDC et. al.

Oct 2nd, 2022 - Type II diabetes mellitus (DM2) is a worldwide disease with an important economic and health impact. Currently, depression, anxiety and stress are common disorders among diabetic populations but their respective prevalence may well be underestimated. So far, Latin American countries have only reported limited information about the impact of mental diseases on DM2 outpatients. The objective of t...