About 335,920 results

Risk of incident type 2 diabetes among patients with rheumatoid arthritis: a population‐based cohort study
Arthritis Care & Research; Jin Y

Aug 3rd, 2020 - We examined risk of incident type 2 diabetes mellitus (T2DM) among RA patients versus four different comparison cohorts.

Cinammon (Cinnamomum Spp.) and Type 2 Diabetes Mellitus

Spices such as cinnamon (Cinnamomum Spp.) have been of interest due to their phytochemical composition that exert hypoglycemic effects with potential for management of type 2 diabetes mellitus (T2DM). We summarize data from 27 manuscripts that include, one book chapter, 3 review articles, 10 randomized controlled trials, 4 systematic reviews with meta-analysis, and 9 preclinical studies. The...

Pros and cons for use of statins in people with coronavirus disease-19 (COVID-19)

Morbidity and mortality from coronavirus disease 2019 (COVID-19) is higher among people with diabetes mellitus (DM), hypertension, and cardiovascular disease (CVD). Statins are used in the majority of people with DM and CVD. This mini-review discusses the current understanding of benefit-risk ratio of use of statins in COVID-19.

Daily improvement of glucose variability by Continuous Glucose Monitoring (CGM)

Continuous Glucose Monitoring (CGM) has been recently applied in the clinical diabetic practice. Authors have continued research of glucose variability. In this study, 51 year-old female patient with Type 1 diabetes mellitus (T1DM) was investigated. She has given multiple daily insulin injection (MDI) for long and her recent daily glucose profile was unstable. After applied with FreeStyle Libre...

Weight loss induced by whole grain-rich diet is through a gut microbiota-independent mechanism

The prevalence of overweight and obesity has increased worldwide. Obesity is a well-known risk factor of type 2 diabetes mellitus and cardiovascular disease and raises public health concerns. Many dietary guidelines encourage the replacement of refined grains with whole grains (WGs) to enhance body weight management. Current evidence regarding interrelationships among WGs, body weight, and gut ...

Health Maintenance in Women

The health maintenance examination is an opportunity to focus on disease prevention and health promotion. The patient history should include screening for tobacco use, alcohol misuse, intimate partner violence, and depression. Premenopausal women should receive preconception counseling and contraception as needed, and all women planning or capable of pregnancy should take 400 to 800 mcg of foli...

Why the Stress-Disease Connection Matters and How to Respond

Family physicians are experts in caring for patients with chronic diseases and recognizing how stress impacts health. These skills naturally complement one another, as attested by research into the connection between chronic disease and stress. Stressors often include adverse childhood experiences, which are traumatic events or chronic stressors experienced in childhood, such as physical or sex...

Continuous Glucose Monitoring in Type 2 Diabetes Is Not Ready for Widespread Adoption

There is great interest in technology to improve health; however, new devices do not always live up to the hype. Although continuous glucose monitoring may benefit patients with type 1 diabetes mellitus, there is limited evidence that it offers similar benefits in patients with type 2 diabetes, regardless of whether they are taking insulin.

Screening of Hyperlipidemia Among Patients With Rheumatoid Arthritis in the United States
Arthritis Care & Research;

To determine the proportion of primary lipid screening among patients with rheumatoid arthritis (RA) and compare it with those among patients with diabetes mellitus (DM) and patients with neither RA nor DM, and to assess whether primary lipid screening varied according to the health care provider (rheumatologist versus non‐rheumatologist).

The relationship between illness perception and medication adherence in patients with d...
Journal of Preventive Medicine and Hygiene; Bilondi SS, Noghabi AD et. al.

May 24th, 2022 - One of the most well-known chronic diseases in the world is diabetes. Disease perception is the patient's organized cognitive representation of his or her illness and can affect treatment adherence. The aim of this study was to investigate the relationship between illness perception and adherence to the medical regimen in patients with type II diabetes mellitus (T2DM). This cross-sectional stud...

Effect of HIV-1 Protease Inhibitor on IL-18 and IL-1β in Rats with Insulinoma.
Disease Markers; Lou H, Guo L

May 24th, 2022 - This study is aimed at investigating the treatment effectiveness of HIV-1 protease inhibitor for rats with insulinoma and its effects on interleukin-1β (IL-1β) and interleukin-18 (IL-18). A total of 40 6-week-old nude mice were included in this study. We randomly assigned 20 rats for insulinoma modeling and divided them into model A and B groups. Another 20 rats were randomly divided into contr...

Derivation and assessment of a sex-specific fetal growth standard.
The Journal of Maternal-fetal & Neonatal Medicine : the O... Blue NR, Allshouse AA et. al.

May 24th, 2022 - To derive a prescriptive sex-specific fetal growth standard and assess clinical management and outcomes according to sex-specific growth status. This was a secondary analysis of the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (nuMoM2b), a prospective observational study of 10,038 nulliparas from eight U.S. centers who underwent ultrasounds at 14-20 and 22-29 weeks with outcom...

The missing heritability in type 1 diabetes mellitus.
Diabetes, Obesity & Metabolism; Pang H, Lin J et. al.

May 24th, 2022 - Type 1 diabetes mellitus (T1DM) is a complex autoimmune disease characterized by an absolute deficiency of insulin. It affects more than 20 million people worldwide and imposes an enormous financial burden on patients. The underlying pathogenic mechanisms of T1DM are still obscure, but it is widely accepted that both genetics and the environment play an important role in its onset and developme...

Retinal Pathophysiological Evaluation in a Rat Model.
Journal of Visualized Experiments : JoVE; Malani M, Nirmal J

May 24th, 2022 - A posterior segment eye disease like diabetic retinopathy alters the physiology of the retina. Diabetic retinopathy is characterized by a retinal detachment, breakdown of the blood-retinal barrier (BRB), and retinal angiogenesis. An in vivo rat model is a valuable experimental tool to examine the changes in the structure and function of the retina. We propose three different experimental techni...

Using community-based participatory research to improve care for American Indians/Alask...
The Nurse Practitioner; Carron R

May 24th, 2022 - American Indians/Alaska Natives are at increased risk for type 2 diabetes mellitus. NPs have the opportunity to intervene with culturally appropriate interventions grounded in community-based participatory research. This article provides an overview of such care that can help improve outcomes.

Prevalence of gestational diabetes and its association with stillbirth, preterm birth, ...
Journal of Preventive Medicine and Hygiene; Darbandi M, Rezaeian S et. al.

May 24th, 2022 - Gestational diabetes mellitus (GDM) is one of the most common metabolic disorders during pregnancy that significantly affects perinatal outcomes. The aim of this study was to determine the prevalence of GDM and its relation with the incidence of stillbirth, preterm birth, macrosomia, abortion and cesarean section (C-section) delivery in pregnant women. This cross-sectional study was conducted o...

Prevalence of diabetic retinopathy in women with pregestational diabetes during pregnan...
Clinical & Experimental Ophthalmology; Widyaputri F, Rogers SL et. al.

May 24th, 2022 - Diabetic retinopathy (DR) may be affected by pregnancy. The majority of prevalence data regarding DR in pregnancy predate the advent of contemporary guidelines for diabetes management during pregnancy. This study reports DR prevalence and associated risk factors in women with pregestational diabetes during pregnancy and the postpartum in Australia. A total of 172 pregnant women with type 1 (T1D...

Childhood Type 1 Diabetes is associated with abnormal bone development.
Pediatric Diabetes; Vora KA, Munns CF et. al.

May 24th, 2022 - To describe bone mineral density (BMD), bone structure and fracture prevalence in adolescents with type 1 diabetes (T1D) and explore their associations with glycemic control and microvascular complications. Cross sectional study of 64 adolescents (38 males) with T1D duration >10 years who underwent dual-energy X-ray absorptiometry (DXA), peripheral quantitative computed tomography (pQCT), fract...

A New Case of Hb Headington (HBB: c.217A>C) Due to a New DNA Transversion, Found in a P...
Hemoglobin Liu Y, Liu B et. al.

May 24th, 2022 - We here report a novel case of Hb Headington [β72(E16)Ser→Arg, HBB: c.217A>C, p.Ser73Arg], in a 68-year-old woman with type 2 diabetes mellitus (T2DM). Glycosylated hemoglobin (Hb) was measured by capillary electrophoresis (CE). The spectrum showed abnormal peaks between the A0 and A2 peaks. DNA sequencing demonstrated a mutation on the HBB gene, which predicted a substitution of serine to argi...

Neuregulin 4 (NRG4) - the hormone with clinical significance in gestational diabetes me...
Journal of Obstetrics and Gynaecology : the Journal of Th... Attique H, Baig S et. al.

May 24th, 2022 - This study aimed at determining the association between serum neuregulin 4 (NRG4) and insulin in gestational diabetes mellitus (GDM) and their correlation with other metabolic parameters. A cross-sectional study was conducted from June 2018 to February 2019 at Ziauddin University, Karachi. Pregnant women (n = 80), at 24-28 weeks of gestation, were recruited. Demographic data, anthropometric mea...