About 315,935 results

Risk of incident type 2 diabetes among patients with rheumatoid arthritis: a population‐based cohort study
Arthritis Care & Research; Jin Y

Aug 3rd, 2020 - We examined risk of incident type 2 diabetes mellitus (T2DM) among RA patients versus four different comparison cohorts.

Cinammon (Cinnamomum Spp.) and Type 2 Diabetes Mellitus

Spices such as cinnamon (Cinnamomum Spp.) have been of interest due to their phytochemical composition that exert hypoglycemic effects with potential for management of type 2 diabetes mellitus (T2DM). We summarize data from 27 manuscripts that include, one book chapter, 3 review articles, 10 randomized controlled trials, 4 systematic reviews with meta-analysis, and 9 preclinical studies. The...

Pros and cons for use of statins in people with coronavirus disease-19 (COVID-19)

Morbidity and mortality from coronavirus disease 2019 (COVID-19) is higher among people with diabetes mellitus (DM), hypertension, and cardiovascular disease (CVD). Statins are used in the majority of people with DM and CVD. This mini-review discusses the current understanding of benefit-risk ratio of use of statins in COVID-19.

Daily improvement of glucose variability by Continuous Glucose Monitoring (CGM)

Continuous Glucose Monitoring (CGM) has been recently applied in the clinical diabetic practice. Authors have continued research of glucose variability. In this study, 51 year-old female patient with Type 1 diabetes mellitus (T1DM) was investigated. She has given multiple daily insulin injection (MDI) for long and her recent daily glucose profile was unstable. After applied with FreeStyle Libre...

Weight loss induced by whole grain-rich diet is through a gut microbiota-independent mechanism

The prevalence of overweight and obesity has increased worldwide. Obesity is a well-known risk factor of type 2 diabetes mellitus and cardiovascular disease and raises public health concerns. Many dietary guidelines encourage the replacement of refined grains with whole grains (WGs) to enhance body weight management. Current evidence regarding interrelationships among WGs, body weight, and gut ...


Atorvastatin is FDA approved, in combination with dietary modifications, to prevent cardiovascular events in patients with cardiac risk factors and for patients with abnormal lipid profiles. Primary prevention: For patients without coronary heart disease, but with multiple risk factors, the FDA has approved atorvastatin to reduce the risk of myocardial infarction, stroke, revascularizati...


Metformin, FDA-approved in 1994, is an antidiabetic agent used in type 2 diabetes mellitus. Metformin comes in both immediate-release and extended-release and is available in several combination products with other antidiabetic agents.

Health Maintenance in Women

The health maintenance examination is an opportunity to focus on disease prevention and health promotion. The patient history should include screening for tobacco use, alcohol misuse, intimate partner violence, and depression. Premenopausal women should receive preconception counseling and contraception as needed, and all women planning or capable of pregnancy should take 400 to 800 mcg of foli...

Why the Stress-Disease Connection Matters and How to Respond

Family physicians are experts in caring for patients with chronic diseases and recognizing how stress impacts health. These skills naturally complement one another, as attested by research into the connection between chronic disease and stress. Stressors often include adverse childhood experiences, which are traumatic events or chronic stressors experienced in childhood, such as physical or sex...

Continuous Glucose Monitoring in Type 2 Diabetes Is Not Ready for Widespread Adoption

There is great interest in technology to improve health; however, new devices do not always live up to the hype. Although continuous glucose monitoring may benefit patients with type 1 diabetes mellitus, there is limited evidence that it offers similar benefits in patients with type 2 diabetes, regardless of whether they are taking insulin.

Chronic Kidney Disease in Diabetes: Guidelines from KDIGO
American Family Physician; Khunti K, de Boer IH et. al.

Jun 1st, 2021 - Diabetes mellitus affects more than 450 million people globally, which could increase to more than 700 million people by 2045. Up to 40% of cases of diabetes are complicated by chronic kidney disease (CKD), with persistent abnormalities of kidney function demonstrated by elevated urine albumin excretion or reduced estimated glomerular filtration rate (eGFR). The Kidney Disease: Improving Global...

Epidemiology of Mucormycosis in India
Microorganisms Prakash H, Chakrabarti A.

Mar 9th, 2021 - Mucormycosis is an angioinvasive disease caused by saprophytic fungi of the order Mucorales. The exact incidence of mucormycosis in India is unknown due to the lack of population-based studies. The estimated prevalence of mucormycosis is around 70 times higher in India than that in global data. Diabetes mellitus is the most common risk factor, followed by haematological malignancy and solid-org...

Screening of Hyperlipidemia Among Patients With Rheumatoid Arthritis in the United States
Arthritis Care & Research;

To determine the proportion of primary lipid screening among patients with rheumatoid arthritis (RA) and compare it with those among patients with diabetes mellitus (DM) and patients with neither RA nor DM, and to assess whether primary lipid screening varied according to the health care provider (rheumatologist versus non‐rheumatologist).

miR-210 hypoxamiR in angiogenesis and diabetes.
Antioxidants & Redox Signaling; Zaccagnini G, Greco S et. al.

Sep 16th, 2021 - microRNA-210 (miR-210) is the master hypoxia-inducible miRNA (hypoxamiR) since it has been found significantly up-regulated under hypoxia in a wide range of cell types. Gene ontology analysis of its targets indicates that miR-210 modulates several aspects of cellular response to hypoxia. Due to its high pleiotropy, miR-210 not only plays a protective role by fine-tuning mitochondrial metabolism...

Variability in insulin pharmacokinetics following high-dose insulin therapy.
Clinical Toxicology (Philadelphia, Pa.); Roberts DM, Hughes HK et. al.

Sep 16th, 2021 - High dose insulin (HDI) therapy for cardiogenic shock from acute poisoning can be complicated by treatable hypoglycemia which persists following poisoning recovery. Glucose requirements post-HDI reflect supraphysiological insulin plasma concentration. A publication reported a patient treated with HDI with plasma insulin concentrations >1000 µU/mL and elimination half-life 10-18 h requiring intr...

A prospective investigation of developmental trajectories of psychosocial adjustment in...
https://doi.org/10.1186/s12887-021-02869-9 10.1007/BF00917244 10.1016/S0140-6736(08)61078-8 10.1093/jpepsy/17.2.133 10.1097/00004703-199304000-00007 10.1037/10188-000 10.1016/j.genhosppsych.2012.01.007 10.1026//0012-1924.49.2.73 10.1186/s12887-016-0727-2
BMC Pediatrics; Warschburger P, Petersen AC et. al.

Sep 16th, 2021 - Relatively little is known about protective factors and the emergence and maintenance of positive outcomes in the field of adolescents with chronic conditions. Therefore, the primary aim of the study is to acquire a deeper understanding of the dynamic process of resilience factors, coping strategies and psychosocial adjustment of adolescents living with chronic conditions. We plan to consecutiv...

Sarcopenia predicts adverse outcomes in an elderly population with coronary artery dise...
https://doi.org/10.1186/s12877-021-02438-w 10.1093/ageing/afy169 10.1007/s13539-010-0014-2 10.1186/s40200-017-0302-x 10.1002/jcsm.12411 10.1002/jcsm.12160 10.11138/ccmbm/2014.11.3.177 10.1177/1457496917748221 10.1097/TA.0000000000001657 10.1097/MD.0000000000012076 10.21037/hbsn.2018.11.05 10.1111/codi.13067 10.1002/mus.880060809 10.1093/gerona/53A.3.M214 10.1046/j.1365-2389.2003.51344.x 10.1152/japplphysiol.00627.2006 10.1097/JES.0b013e3182a4e699 10.1016/j.clnu.2019.01.009 10.1016/j.jamda.2011.01.003 10.11005/jbm.2019.26.2.65 10.1097/QAD.0000000000001798 10.5935/0101-2800.20150014 10.2147/DMSO.S186600 10.1177/2047487316653709 10.1186/1471-2261-8-16 10.5935/abc.20130198 10.1186/s12872-017-0660-9 10.4103/aca.ACA_20_17 10.1161/JAHA.120.017712 10.1016/j.ijcard.2016.07.167 10.1007/s40520-016-0534-5 10.1016/j.ijcard.2016.04.128 10.1016/j.ejim.2015.01.008 10.1016/S0140-6736(96)07015-8 10.1016/j.athoracsur.2018.02.010 10.1093/ejcts/ezz378 10.1016/j.jtcvs.2018.06.098 10.11909/j.issn.1671-5411.2019.10.002 10.5551/jat.52282 10.5152/tao.2019.4058 10.4103/0253-7184.69003 10.1186/s12933-017-0617-4 10.1161/JAHA.119.014908 10.1186/1471-2288-14-45 10.1136/bmj.d5928 10.1002/9781119536604 10.1161/JAHA.120.017315 10.33879/AMH.2019.1809 10.1016/j.exger.2019.110801 10.1186/s12877-020-01672-y 10.1186/s13098-018-0326-5 10.1136/bmjdrc-2017-000404 10.1097/MCO.0b013e328312c37d 10.1097/01.med.0000433071.11466.7f 10.1001/jama.2013.281901 10.1016/j.cjca.2017.12.005 10.1161/CIRCRESAHA.120.316101 10.1161/CIR.0000000000000207 10.1161/HYPERTENSIONAHA.116.07854 10.1155/2013/653789 10.14797/mdcj-13-2-68 10.1161/JAHA.113.000272 10.1016/S0261-5614(13)60457-4 10.1155/2011/840512 10.1155/2013/985404 10.1210/jc.2004-0545 10.1016/j.maturitas.2017.04.007 10.1186/s12877-019-1338-1 10.1371/journal.pone.0169548 10.1016/j.ejca.2015.12.030 10.1186/s12885-020-6645-6 10.1016/j.jamda.2017.03.011 10.1016/j.ijcard.2017.01.110 10.1186/1477-7525-1-42 10.1186/s12955-020-01433-w 10.18553/jmcp.2015.21.6.443 10.1371/journal.pone.0237740
BMC Geriatrics; Xue Q, Wu J et. al.

Sep 16th, 2021 - The development of sarcopenia is attributed to normal aging and factors like type 2 diabetes, obesity, inactivity, reduced testosterone levels, and malnutrition, which are factors of poor prognosis in patients with coronary artery disease (CAD). This study aimed to perform a meta-analysis to assess whether preoperative sarcopenia can be used to predict the outcomes after cardiac surgery in elde...

Multimorbidity and achievement of treatment goals among patients with type 2 diabetes: ...
https://doi.org/10.1186/s12913-021-06989-x 10.1016/S0140-6736(18)32279-7 10.1038/nrendo.2017.151 10.1016/j.diabres.2009.10.007 10.1371/journal.pone.0194127 10.1038/s41588-018-0241-6 10.1007/s00125-019-04985-9 10.1136/bmjopen-2020-039625 10.1136/bmjopen-2019-033866 10.1371/journal.pmed.1003094 10.2147/DMSO.S186758 10.1016/j.diabres.2019.107804 10.1001/jamanetworkopen.2019.19099 10.2337/diacare.29.03.06.dc05-2078 10.1016/j.jdiacomp.2014.10.003 10.1111/1475-6773.12607 10.1370/afm.1848 10.1097/MLR.0b013e31820f0ed0 10.1371/journal.pone.0209585 10.1177/2235042X19870934 10.3109/02813432.2016.1153242 10.1093/gerona/glq208 10.1097/HJH.0b013e328308da66 10.3109/02813432.2015.1132886 10.1177/2235042X18801658 10.1007/s13300-018-0477-2 10.1016/j.berh.2017.09.004 10.1371/journal.pone.0212030 10.1136/pgmj.2010.146399 10.1002/dmrr.3224 10.1186/1471-2458-9-88 10.1007/s00592-019-01295-9 10.1016/j.pcd.2016.02.003 10.3389/fendo.2019.00259 10.1186/s13033-020-00413-3 10.1016/j.diabres.2019.107816 10.1002/brb3.1981
BMC Health Services Research; Heikkala E, Mikkola I et. al.

Sep 16th, 2021 - Type 2 diabetes (T2D), with its prevalence and disability-causing nature, is a challenge for primary health care. Most patients with T2D are multimorbid, i.e. have one or more long-term diseases in addition to T2D. Multimorbidity may play a role in the achievement of T2D treatment targets, but is still not fully understood. The aims of the present cross-sectional, register-based study were to e...

Effect of diabetes mellitus on the development of left ventricular contractile dysfunct...
https://doi.org/10.1186/s12933-021-01379-3 10.1016/j.jacc.2017.08.074 10.1016/j.jchf.2018.06.008 10.1016/j.jacc.2018.11.033 10.1016/j.ijcard.2021.01.052 10.1016/j.hfc.2018.08.002 10.1002/ejhf.67 10.1161/CIRCHEARTFAILURE.119.006539 10.1161/JAHA.119.012190 10.3390/jcm8060792 10.1016/j.ijcard.2020.01.003 10.1016/j.ijcard.2019.01.039 10.1016/j.jchf.2016.09.015 10.1016/j.jacc.2014.05.030 10.1186/s12933-017-0506-x 10.1093/eurheartj/ehz641 10.1186/s12968-020-00610-6 10.1016/j.cjca.2016.03.017 10.1016/j.jacc.2018.01.083 10.1007/s00392-013-0585-y 10.1002/ejhf.1227 10.1161/JAHA.119.013114 10.1002/ejhf.1535 10.1186/s12933-021-01242-5 10.1161/CIRCULATIONAHA.115.015884 10.1148/radiol.2020200195 10.1186/s12933-020-01138-w 10.1186/s12916-016-0762-8 10.1016/j.jacc.2019.12.049 10.1186/s12968-018-0477-4 10.1016/j.ijcard.2018.09.103 10.1186/s12933-019-0833-1 10.1161/CIRCULATIONAHA.117.032474 10.1161/CIRCULATIONAHA.117.031622 10.1016/j.jchf.2019.01.003 10.1161/JAHA.116.003330 10.1186/s12933-020-01011-w 10.1016/j.ypmed.2020.106155
Cardiovascular Diabetology; Shi K, Yang MX et. al.

Sep 16th, 2021 - Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome with sex-specific pathophysiology. Estrogen deficiency is believed to be responsible for the development of HFpEF in women. However, estrogen deficiency does not seem to be completely responsible for the differences in HFpEF prevalence between sexes. While diabetes mellitus (DM) frequently coexists with HFpEF in ...

Body weight changes in patients with type 2 diabetes and a recent acute coronary syndro...
https://doi.org/10.1186/s12933-021-01382-8 10.1007/s00592-018-1126-y 10.1093/eurheartj/ehaa293 10.2337/dc06-2544 10.1016/s0140-6736(09)60318-4 10.1056/NEJMoa1000367 10.1007/s00392-019-01453-7 10.7326/m14-1551 10.1371/journal.pone.0146889 10.1056/NEJMoa1212914 10.1016/j.ahj.2011.08.004 10.1056/NEJMoa1305889 10.1016/j.ahj.2020.07.014 10.1111/dom.14371 10.1002/ejhf.240 10.1093/eurheartj/ehn420 10.1046/j.1523-1755.2003.00803.x 10.1186/s12933-020-01170-w 10.1186/s12933-019-0934-x 10.1186/s12933-021-01285-8 10.1016/s0140-6736(13)61249-0 10.1016/j.jacc.2019.07.020 10.1016/s0140-6736(13)60687-x 10.1111/j.1523-1755.2004.00863.x 10.1161/circheartfailure.114.001957 10.1186/s12933-021-01326-2
Cardiovascular Diabetology; Ferreira JP, Rossignol P et. al.

Sep 16th, 2021 - Patients with type 2 diabetes (T2D) may experience frequent body weight changes over time. The prognostic impact of these weight changes (gains or losses) requires further study. To study the associations between changes in body weight (intentional or unintentional) with subsequent outcomes. The EXAMINE trial included 5380 patients with T2D and a recent acute coronary syndrome, who were randomi...