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About 1,910,413 results

Cost-Effectiveness Analysis of Triple Therapy with Budesonide/ Glycopyrronium/ Formoter...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675425
International Journal of Chronic Obstructive Pulmonary Di... Trigueros JA, Garin N et. al.

Nov 23rd, 2022 - To evaluate the cost-effectiveness of Budesonide/Glycopyrronium/Formoterol (BUD/GLY/FOR) versus LAMA/LABA and ICS/LABA, respectively, in patients with moderate to severe COPD, from the Spanish National Healthcare System (NHS) perspective. A lifetime Markov model with monthly cycle length was developed with baseline and treatment effect data from ETHOS clinical trial, together with utility value...

Predictors of early response to balloon pulmonary angioplasty in patients with inoperab...
https://doi.org/10.1177/17534666221138001
Therapeutic Advances in Respiratory Disease; Li X, Zhang Y et. al.

Nov 23rd, 2022 - To achieve favorable hemodynamics, the number of balloon pulmonary angioplasty (BPA) sessions varied significantly among patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Increased BPA sessions burdened patients financially and psychologically. We aim to identify baseline characteristics that could predict early BPA response. Consecutive patients who were diagnosed...

Mini Female Health Program for detection of non-communicable diseases in Women - In a u...
https://doi.org/10.1177/17455057221135493
Women's Health (London, England); Sangu PV, Balakrishna N et. al.

Nov 23rd, 2022 - Prevalence of non-communicable diseases (NCDs) is increasing with women affected at an early age. The Mini Female Health Program (MFHP) is a simple screening package to detect NCDs in women. Determine the prevalence of selected NCDs in a hospital-based outpatient setting using MFHP. A cross-sectional observational study was conducted in an urban teaching hospital in India. MFHP included medical...

Prognostic factors and perinatal outcomes in early-onset intrauterine growth restrictio...
https://doi.org/10.1080/14767058.2021.1944092
The Journal of Maternal-fetal & Neonatal Medicine : the O... Faquini SLDL, Guerra GVQL et. al.

Nov 23rd, 2022 - To determine the principal prognostic factors and neonatal outcomes associated with perinatal death in cases of early-onset intrauterine growth restriction (IUGR) due to placental insufficiency and to define the cutoff point for the risk of perinatal death. A retrospective cohort study conducted with 198 pregnant women with a diagnosis of early-onset IUGR (as detected before the 32nd week of ge...

Treating and Managing Laryngopharyngeal Reflux Disease in the Over 65s: Evidence to Date.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675328
Clinical Interventions in Aging; Lechien JR

Nov 23rd, 2022 - The clinical presentation and therapeutic outcomes of elderly patients may be different from those in younger populations, leading to additional diagnostic and therapeutic difficulties. The present study reviewed the findings on the epidemiology, and clinical, diagnostic, and therapeutic outcomes of elderly patients with laryngopharyngeal reflux (LPR). A PubMed, Cochrane Library, and Scopus lit...

Coexpression Network Analysis-Based Identification of Critical Genes Differentiating be...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674975
Disease Markers; Chen L, Hua J et. al.

Nov 23rd, 2022 - Three Gene Expression Omnibus (GEO) microarray datasets (GSE19491, GSE98461, and GSE152532) were downloaded, with GSE19491 and GSE98461 then being merged to form a training dataset. Hub genes capable of differentiating between ATB and LTBI were then identified through differential expression analyses and a WGCNA analysis of this training dataset. Receiver operating characteristic (ROC) curves w...

Differential Expression of Serum Proteins in Chronic Obstructive Pulmonary Disease Asse...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675428
International Journal of Chronic Obstructive Pulmonary Di... Li R, Zhao X et. al.

Nov 23rd, 2022 - As a common respiratory disease, chronic obstructive pulmonary disease (COPD) has a high morbidity and mortality. Current clinical therapies are not ideal and do not improve lung function or long-term life quality. It is very important to find new potential pathogenic mechanisms, biomarkers, and targets with therapeutic value in COPD. Serum samples collected from acute exacerbation and stable C...

Validity and Reliability of the Chinese Version of the Edinburgh Postnatal Depression S...
https://doi.org/10.1177/15579883221138191
American Journal of Men's Health; Jen WH, Hung TH et. al.

Nov 23rd, 2022 - Studies often use the Edinburgh Postnatal Depression Scale (EPDS) or the Beck Depression Inventory-II (BDI-II) as a screening tool for depression in new mothers or fathers following the birth of an infant, but no studies have evaluated EPDS as a predictor of postnatal depression for new fathers in a Chinese population. This study aimed to test the validity and reliability of a Chinese version o...

Subclinical and clinical atherosclerosis in non-alcoholic fatty liver disease is associ...
https://doi.org/10.1016/j.numecd.2022.08.005
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Cattazzo F, Lombardi R et. al.

Nov 22nd, 2022 - Non-alcoholic fatty liver disease (NAFLD) is associated with increased cardiovascular (CV) risk. However, it is unclear whether NAFLD contributes independently to the development of CV disease. Our study aimed at assessing the differences in several indices of atherosclerosis, arterial stiffness and cardiac morphology among patients with isolated NAFLD, isolated hypertension (HT) or a combinati...

High incidence combination of multiple primary malignant tumors of the digestive system.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669828
World Journal of Gastroenterology; Yang XB, Zhang LH et. al.

Nov 22nd, 2022 - Clinical reports of multiple primary malignant tumors (MPMTs) in the digestive system are increasing. In China, although the survival rate of patients with MPMTs is increasing, the quality of life is very low. Many patients have reached the advanced stage when the second primary tumor is found, resulting in no early intervention and treatment. This is due to the misunderstanding of MPMTs by cli...

Clinical value of predictive models based on liver stiffness measurement in predicting ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669823
World Journal of Gastroenterology; Lai RM, Wang MM et. al.

Nov 22nd, 2022 - Assessment of liver reserve function (LRF) is essential for predicting the prognosis of patients with chronic liver disease (CLD) and determines the extent of liver resection in patients with hepatocellular carcinoma. To establish noninvasive models for LRF assessment based on liver stiffness measurement (LSM) and to evaluate their clinical performance. A total of 360 patients with compensated ...

Esophageal lichen planus: Current knowledge, challenges and future perspectives.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669830
World Journal of Gastroenterology; Decker A, Schauer F et. al.

Nov 22nd, 2022 - Lichen planus (LP) is a frequent, chronic inflammatory disease involving the skin, mucous membranes and/or skin appendages. Esophageal involvement in lichen planus (ELP) is a clinically important albeit underdiagnosed inflammatory condition. This narrative review aims to give an overview of the current knowledge on ELP, its prevalence, pathogenesis, clinical manifestation, diagnostic criteria, ...

Hypermixed Convolutional Neural Network for Retinal Vein Occlusion Classification.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674409
Disease Markers; Zhang G, Sun B et. al.

Nov 22nd, 2022 - Retinal vein occlusion (RVO) is one of the most common retinal vascular diseases leading to vision loss if not diagnosed and treated in time. RVO can be classified into two types: CRVO (blockage of the main retinal veins) and BRVO (blockage of one of the smaller branch veins). Automated diagnosis of RVO can improve clinical workflow and optimize treatment strategies. However, to the best of our...

Fungating Malignancies: Management of a Distinct Wound Entity.
https://doi.org/10.1097/01.ASW.0000892972.45960.fa
Advances in Skin & Wound Care;

Nov 22nd, 2022 - Fungating Malignancies: Management of a Distinct Wound Entity.|2022||diagnosis,therapy,

Papillary and Peripapillary Hemorrhages in Eyes With Pathologic Myopia.
https://doi.org/10.1167/iovs.63.12.28
Investigative Ophthalmology & Visual Science; Xiong J, Du R et. al.

Nov 22nd, 2022 - To determine the prevalence, characteristics, and causes of papillary and peripapillary hemorrhages (PPHs) in eyes with pathologic myopia (PM). PM patients were retrospectively studied between 2011 and 2018. Fundus images were used to diagnose and classify the PPHs. Fundus fluorescein angiographic (FFA) and optical coherence tomographic (OCT) images were used to determine the status of the reti...

Assessing the Utility of Mental Health First Aid Training for Physician Assistant Stude...
https://doi.org/10.1097/JPA.0000000000000467
The Journal of Physician Assistant Education : the Offici... Forbes J, Noller DT et. al.

Nov 22nd, 2022 - Physician assistant (PA) students are at increased risk for anxiety and depression compared with the general population. The demands of studying medicine can contribute to a decline in mental health, which may impede a student's ability to progress in his or her PA program. Mental Health First Aid (MHFA) is one strategy that can be used to increase mental health literacy, promote help-seeking b...

Case 308: Van Wyk-Grumbach Syndrome.
https://doi.org/10.1148/radiol.211119
Radiology Kandasamy D, Malik R et. al.

Nov 22nd, 2022 - An 11-year-old girl presented to the pediatric gastroenterology outpatient department of our institution with gradually increasing painless abdominal distention. The distention started 2 years earlier and was not associated with any other constitutional symptoms, vomiting, diarrhea, jaundice, hematemesis, or melaena. She reported early satiety and heaviness in the lower abdomen. The abdominal s...

Determinants of the progression to type 2 diabetes and regression to normoglycemia in p...
https://doi.org/10.1016/j.pcd.2022.10.002
Primary Care Diabetes; Kohansal K, Ahmadi N et. al.

Nov 22nd, 2022 - To determine the rates and predictors of the regression to normoglycemia and progression to diabetes among subjects with pre-diabetes. A 10-year longitudinal population-based study was conducted among 1329 participants with pre-diabetes in the Tehran Lipid and Glucose Study. Pre-diabetes was divided into isolated IFG (iIFG), isolated IGT (iIGT), and combined IFG/IGT. Univariate and stepwise mul...

Solitary Involvement of the Liver: A Rare Manifestation of Langerhans Cell Histiocytosis.
https://doi.org/10.12659/AJCR.937628
The American Journal of Case Reports; Consing M, Lee HE et. al.

Nov 22nd, 2022 - BACKGROUND Langerhans cell histiocytosis (LCH) is a rare condition caused by a neoplastic proliferation of myeloid cells. It can present as a single-system or multi-system disorder. Worse prognosis is associated with the hematopoietic system (spleen, liver, bone marrow), which is routinely observed in multi-system disease. Because of the varied presentation of this disorder, diagnosis can be di...

Orbital apex inflammation: a curious case of COVID-19.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9635761
Digital Journal of Ophthalmology : DJO; Hussain A, Fazzone H et. al.

Nov 22nd, 2022 - A 25-year-old man presented to an urgent care facility with sudden loss of vision in his right eye, diplopia, and anosmia. He tested positive by reverse-transcription polymerase chain reaction for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Nine days later, he presented at our emergency department, at which time ophthalmic examination revealed reduced visual acuity i...