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About 151,913 results

Race-Ethnic Differences of ST-Elevation Myocardial Infarction: Findings from a New York...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311301
Ethnicity & Disease; Murray CSG, Zamora C et. al.

Aug 2nd, 2022 - Race and ethnicity are major considerations in the incidence, management, and long-term outcome of ST-elevation myocardial infarction (STEMI) in the United States, but there is limited existing comparative data. We assembled a registry in a health system serving Bronx, NY of STEMI patients from 2008-2014 and analyzed differences in presentation, treatment and mortality between Hispanic/Latino (...

Disparities in Cardiovascular Mortality Between Black and White Adults in the United St...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310198
Circulation Kyalwazi AN, Loccoh EC et. al.

Jul 22nd, 2022 - Black adults experience a disproportionately higher burden of cardiovascular risk factors and disease in comparison with White adults in the United States. Less is known about how sex-based disparities in cardiovascular mortality between these groups have changed on a national scale over the past 20 years, particularly across geographic determinants of health and residential racial segregation....

Racial and Ethnic Differences in All-Cause and Cardiovascular Disease Mortality: The ME...
https://doi.org/10.1161/CIRCULATIONAHA.122.059174
Circulation Post WS, Watson KE et. al.

Jul 22nd, 2022 - Despite improvements in population health, marked racial and ethnic disparities in longevity and cardiovascular disease (CVD) mortality persist. This study aimed to describe risks for all-cause and CVD mortality by race and ethnicity, before and after accounting for socioeconomic status (SES) and other factors, in the MESA study (Multi-Ethnic Study of Atherosclerosis). MESA recruited 6814 US ad...

The sequences of 150,119 genomes in the UK Biobank.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329122
Nature Halldorsson BV, Eggertsson HP et. al.

Jul 22nd, 2022 - Detailed knowledge of how diversity in the sequence of the human genome affects phenotypic diversity depends on a comprehensive and reliable characterization of both sequences and phenotypic variation. Over the past decade, insights into this relationship have been obtained from whole-exome sequencing or whole-genome sequencing of large cohorts with rich phenotypic data1,2. Here we describe the...

Increases in Disparities in US Drug Overdose Deaths by Race and Ethnicity: Opportunitie...
https://doi.org/10.1001/jama.2022.12240
JAMA Kariisa M, Seth P et. al.

Jul 20th, 2022 - Increases in Disparities in US Drug Overdose Deaths by Race and Ethnicity: Opportunities for Clinicians and Health Systems.|2022|Kariisa M,Seth P,Jones CM,|standards,statistics & numerical data,ethnology,mortality,statistics & numerical data,statistics & numerical data,statistics & numerical data,epidemiology,

Disparities in trial enrollment and outcomes of Hispanic adolescent and young adult acu...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327550
Blood Advances; Muffly L, Yin J et. al.

Jul 16th, 2022 - In this secondary analysis of Hispanic adolescents and young adults (AYA) with acute lymphoblastic leukemia (ALL) treated on Cancer and Leukemia Group B (CALGB) 10403, we evaluated outcomes and geographic enrollment patterns relative to US population data. We used demographic, clinical, and survival data on AYAs enrolled on CALGB 10403 (N = 295, 2007-2012). Surveillance, Epidemiology, and End R...

Subclinical Atherosclerosis in Young, Socioeconomically Vulnerable Hispanic and Non-His...
https://doi.org/10.1016/j.jacc.2022.04.054
Journal of the American College of Cardiology; Iglesies-Grau J, Fernandez-Jimenez R et. al.

Jul 15th, 2022 - Non-Hispanic Black persons are at greater risk of cardiovascular (CV) events than other racial/ethnic groups; however, their differential vulnerability to early subclinical atherosclerosis is poorly understood. This work aims to study the impact of race/ethnicity on early subclinical atherosclerosis in young socioeconomically disadvantaged adults. Bilateral carotid and femoral 3-dimensional vas...

Changes in the Relationship Between Income and Life Expectancy Before and During the CO...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264223
JAMA Schwandt H, Currie J et. al.

Jul 8th, 2022 - The COVID-19 pandemic caused a large decrease in US life expectancy in 2020, but whether a similar decrease occurred in 2021 and whether the relationship between income and life expectancy intensified during the pandemic are unclear. To measure changes in life expectancy in 2020 and 2021 and the relationship between income and life expectancy by race and ethnicity. Retrospective ecological anal...

Racial social norms among Brazilian students: Academic performance, popularity, and rac...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271153
Proceedings of the National Academy of Sciences of the Un... Portella A, Kirschbaum C et. al.

Jul 1st, 2022 - Studies in the United States have shown that minority students might face a trade-off between better academic performance and peer acceptance, which has been termed "acting White." This paper investigates racial differences in the relationship between grades and popularity in five Brazilian schools. Popularity is measured using friendship ties among students, assigning a higher value to student...

Network-based meta-analysis and the candidate gene association studies reveal novel eth...
https://doi.org/10.1002/ajmg.b.32908
American Journal of Medical Genetics. Part B, Neuropsychi... Shigemizu D, Asanomi Y et. al.

Jun 30th, 2022 - Dementia with Lewy bodies (DLB) is the second most common form of neurodegenerative dementia in elderly people, following Alzheimer's disease. Only three genes, SNCA (α-synuclein), APOE (apolipoprotein E), and GBA (glucosylceramidase), have been convincingly demonstrated to be associated with DLB. Here, we applied whole-genome sequencing to blood samples from 61 DLB patients and 45 cognitively ...

Assessing inequities underlying racial disparities of COVID-19 mortality in Louisiana p...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271191
Proceedings of the National Academy of Sciences of the Un... Hu G, Hamovit N et. al.

Jun 28th, 2022 - High COVID-19 mortality among Black communities heightened the pandemic's devastation. In the state of Louisiana, the racial disparity associated with COVID-19 mortality was significant; Black Americans accounted for 50% of known COVID-19-related deaths while representing only 32% of the state's population. In this paper, we argue that structural racism resulted in a synergistic framework of cu...

White patients' physical responses to healthcare treatments are influenced by provider ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9271156
Proceedings of the National Academy of Sciences of the Un... Howe LC, Hardebeck EJ et. al.

Jun 25th, 2022 - The healthcare workforce in the United States is becoming increasingly diverse, gradually shifting society away from the historical overrepresentation of White men among physicians. However, given the long-standing underrepresentation of people of color and women in the medical field, patients may still associate the concept of doctors with White men and may be physiologically less responsive t...

Racial Discrimination to Bullying Behavior among White and Black Adolescents in the USA...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222328
International Journal of Environmental Research and Publi... Hong JS, Kim DH et. al.

Jun 25th, 2022 - The present study proposes and tests pathways by which racial discrimination might be positively related to bullying victimization among Black and White adolescents. Data were derived from the 2016 National Survey of Children's Health, a national survey that provides data on children's physical and mental health and their families. Data were collected from households with one or more children b...

Effects of a WHO-guided digital health intervention for depression in Syrian refugees i...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223343
PLoS Medicine; Cuijpers P, Heim E et. al.

Jun 24th, 2022 - Most displaced people with mental disorders in low- and middle-income countries do not receive effective care, and their access to care has deteriorated during the Coronavirus Disease 2019 (COVID-19) pandemic. Digital mental health interventions are scalable when digital access is adequate, and they can be safely delivered during the COVID-19 pandemic. We examined whether a new WHO-guided digit...

Association of genetic polymorphisms of PCSK9 with type 2 diabetes in Uygur Chinese pop...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219175
BMC Cardiovascular Disorders; Wang MM, Lu CF et. al.

Jun 23rd, 2022 - PCSK9 gene expression is associated with biological processes such as lipid metabolism, glucose metabolism, and inflammation. In the present study, our primary objective was to assess the association between the single-nucleotide polymorphisms in the PCSK9 gene and type 2 diabetes in Uygur subjects, in Xinjiang, China. We designed a case-control study including 662 patients diagnosed with T2DM ...

Evaluating the strengths and challenges of PAX dream makers approach to mental health p...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225784
International Journal of Circumpolar Health; Chartier MJ, Phanlouvong A et. al.

Jun 22nd, 2022 - PAX Good Behaviour Game (PAX-GBG) is an evidence-based approach to co-create a nurturing environment where all children can thrive. This school-based approach was identified as a promising intervention for suicide prevention by First Nations communities in Manitoba, Canada. To enhance this mental health promotion approach, PAX Dream Makers was developed. It is a youth-led addition to PAX-GBG fo...

Perceptions of COVID-19 self-testing and recommendations for implementation and scale-u...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207861
BMC Public Health; Nwaozuru U, Obiezu-Umeh C et. al.

Jun 21st, 2022 - COVID-19 self-testing (ST) is an innovative strategy with the potential to increase the access and uptake of testing and ultimately to limit the spread of the virus. To maximize the uptake and reach of this promising strategy and inform intervention development and scale up, research is needed to understand the acceptability of and willingness to use this tool. This is vital to ensure that Blac...

Effect of Varenicline Added to Counseling on Smoking Cessation Among African American D...
https://doi.org/10.1001/jama.2022.8274
JAMA Cox LS, Nollen NL et. al.

Jun 15th, 2022 - African American smokers have among the highest rates of tobacco-attributable morbidity and mortality in the US, and effective treatment is needed for all smoking levels. To evaluate the efficacy of varenicline vs placebo among African American adults who are light, moderate, and heavy daily smokers. The Kick It at Swope IV (KIS-IV) trial was a randomized, double-blind, placebo-controlled clini...

African researchers lead campaign for equity in global collaborations.
https://doi.org/10.1038/d41586-022-01604-3
Nature Else H

Jun 11th, 2022 - African researchers lead campaign for equity in global collaborations.|2022|Else H,|ethnology,organization & administration,ethics,prevention & control,ethics,organization & administration,

Efficacy and safety of lorlatinib in Asian and non-Asian patients with ALK-positive adv...
https://doi.org/10.1016/j.lungcan.2022.05.012
Lung Cancer (Amsterdam, Netherlands); Soo RA, Huat Tan E et. al.

Jun 7th, 2022 - To analyze the efficacy and safety of lorlatinib in Asian and non-Asian patients with pretreated anaplastic lymphoma kinase (ALK)-positive, advanced non-small cell lung cancer (NSCLC) from a phase 1/2 study. In this ongoing phase 2 part of the trial, patients with ALK- or ROS1-positive, advanced NSCLC enrolled into six expansion cohorts (EXP1-6), based on ALK and ROS1 status and previous therap...