About 85,573 results

The tangled history of mRNA vaccines.
https://doi.org/10.1038/d41586-021-02483-w 10.1073/pnas.86.16.6077 10.1038/274923a0 10.1038/274921a0 10.1093/nar/12.18.7035 10.1093/nar/12.18.7057 10.1126/science.1690918 10.1002/eji.1830230749 10.1126/science.1546298 10.1084/jem.184.2.465 10.1002/1521-4141(200001)30:1<1::AID-IMMU1>3.0.CO;2-# 10.1038/sj.gt.3302964 10.1016/S0005-2736(97)00238-1 10.1038/sj.gt.3300930 10.1074/jbc.M310175200 10.1016/j.immuni.2005.06.008 10.1016/j.stem.2010.08.012 10.1016/j.vaccine.2020.12.070 10.1007/s00508-021-01922-y 10.1007/s11095-004-1873-z 10.1073/pnas.1209367109
Nature Dolgin E

Sep 16th, 2021 - The tangled history of mRNA vaccines.|2021|Dolgin E,|economics,history,history,chemistry,genetics,immunology,therapy,history,metabolism,biosynthesis,genetics,history,history,chemistry,immunology,immunology,history,adverse effects,history,therapeutic use,

New insight into the mechanism of granulocyte colony-stimulating factor (G-CSF) that in...
Hematology (Amsterdam, Netherlands); Theyab A, Algahtani M et. al.

Sep 9th, 2021 - Over the past 20 years, granulocyte colony-stimulating factor (G-CSF) has driven the attention of researchers as a therapeutic agent for curing patients suffering from neutropenia. Despite the successful use of G-CSF, it currently requires daily injections, which are inconvenient, expensive, and distressing for children. Therefore, an alternative strategy for using G-CSF for treatment is needed...

Kazuto Kato: the ethics of editing humanity.
Bulletin of the World Health Organization;

Sep 4th, 2021 - Gary Humphreys talks to Kazuto Kato about the ethical and societal challenges posed by biotechnologies that allow for the editing of the human genome.

Remembering Past Lessons about Structural Racism - Recentering Black Theorists of Healt...
The New England Journal of Medicine; White A, Thornton RLJ et. al.

Sep 2nd, 2021 - Remembering Past Lessons about Structural Racism - Recentering Black Theorists of Health and Society.|2021|White A,Thornton RLJ,Greene JA,|history,history,history,history,history,history,ethnology,history,

Public investments in the development of GeneXpert molecular diagnostic technology.
PloS One; Gotham D, McKenna L et. al.

Sep 1st, 2021 - The GeneXpert diagnostic platform from the US based company Cepheid is an automated molecular diagnostic device that performs sample preparation and pathogen detection within a single cartridge-based assay. GeneXpert devices can enable diagnosis at the district level without the need for fully equipped clinical laboratories, are simple to use, and offer rapid results. Due to these characteristi...

A Brief History, the Progress in the Variants of Therapies against Metastatic Neoplasms...
Annals of Clinical and Laboratory Science; Zhang KJ, Qu Z et. al.

Aug 29th, 2021 - Chemotherapy originated in the early 1960s. The initial chemotherapeutic agents focused on blocking metabolic pathways and found substantial success in certain types of tumors, but they are generally considered toxic to all normal and tumor cells, and they have significant side effects. As more scientific studies began to identify many new, specific targets and mutations, along with a multitude...

The Death of Florence Nightingale.
The American Journal of Nursing;

Aug 27th, 2021 - Editor's note: From its first issue in 1900 through to the present day, AJN has unparalleled archives detailing nurses' work and lives over more than a century. These articles not only chronicle nursing's growth as a profession within the context of the events of the day, but also reveal prevailing societal attitudes about women, health care, and human rights. Today's nursing school curricula r...

Forty-Year Anniversary of Arteriosclerosis, Thrombosis, and Vascular Biology.
Arteriosclerosis, Thrombosis, and Vascular Biology; Daugherty A, Fisher EA et. al.

Aug 26th, 2021 - Forty-Year Anniversary of Arteriosclerosis, Thrombosis, and Vascular Biology.|2021|Daugherty A,Fisher EA,Taubman MB,Heistad DD,Fogelman AM,|history,metabolism,pathology,therapy,history,history,history,metabolism,pathology,therapy,

Climatic windows for human migration out of Africa in the past 300,000 years.
Nature Communications; Beyer RM, Krapp M et. al.

Aug 26th, 2021 - Whilst an African origin of modern humans is well established, the timings and routes of their expansions into Eurasia are the subject of heated debate, due to the scarcity of fossils and the lack of suitably old ancient DNA. Here, we use high-resolution palaeoclimate reconstructions to estimate how difficult it would have been for humans in terms of rainfall availability to leave the African c...

Intensity and frequency of extreme novel epidemics.
Proceedings of the National Academy of Sciences of the Un... Marani M, Katul GG et. al.

Aug 25th, 2021 - Observational knowledge of the epidemic intensity, defined as the number of deaths divided by global population and epidemic duration, and of the rate of emergence of infectious disease outbreaks is necessary to test theory and models and to inform public health risk assessment by quantifying the probability of extreme pandemics such as COVID-19. Despite its significance, assembling and analyzi...

A New Medico-Legal Question.

Aug 25th, 2021 - A New Medico-Legal Question.|2021||history,therapeutic use,history,legislation & jurisprudence,history,therapy,

Dan Stein: casting a wide net to understand mental health.
The Lancet. Psychiatry; Morgan J

Aug 23rd, 2021 - Dan Stein: casting a wide net to understand mental health.|2021|Morgan J,|history,

Love is all: Paul Goesch and the Madonna.
The Lancet. Psychiatry; Strube S, Steinberg H

Aug 23rd, 2021 - Love is all: Paul Goesch and the Madonna.|2021|Strube S,Steinberg H,|history,history,history,

Patterns of genetic connectedness between modern and medieval Estonian genomes reveal t...
American Journal of Human Genetics; Kivisild T, Saag L et. al.

Aug 20th, 2021 - The Finnish population is a unique example of a genetic isolate affected by a recent founder event. Previous studies have suggested that the ancestors of Finnic-speaking Finns and Estonians reached the circum-Baltic region by the 1st millennium BC. However, high linguistic similarity points to a more recent split of their languages. To study genetic connectedness between Finns and Estonians dir...

Henrik Sjögren (1899-1986): the syndrome and his legacy.
Annals of the Rheumatic Diseases; Jonsson R

Aug 14th, 2021 - Henrik Sjögren (1899-1986): the syndrome and his legacy.|2021|Jonsson R,|history,history,

The Pellagra Problem.

Aug 11th, 2021 - The Pellagra Problem.|2021||history,epidemiology,history,prevention & control,epidemiology,

The Doctors Blackwell-Biography of Pioneering Women in Medicine.
JAMA Eckhert NL

Aug 11th, 2021 - The Doctors Blackwell-Biography of Pioneering Women in Medicine.|2021|Eckhert NL,|history,history,history,history,history,

IPCC climate report: Earth is warmer than it's been in 125,000 years.
Nature Tollefson J

Aug 11th, 2021 - IPCC climate report: Earth is warmer than it's been in 125,000 years.|2021|Tollefson J,|trends,statistics & numerical data,legislation & jurisprudence,trends,history,legislation & jurisprudence,prevention & control,statistics & numerical data,history,legislation & jurisprudence,prevention & control,statistics & numerical data,history,legislation & jurisprudence,statistics & numerical data,trends,

A history of psychiatry in 1500 words.
BMJ (Clinical Research Ed.); Hilton C

Aug 11th, 2021 - A history of psychiatry in 1500 words.|2021|Hilton C,|trends,epidemiology,therapy,legislation & jurisprudence,history,

The African American experience in reproductive medicine: provider, patient, and pipeli...
Fertility and Sterility; Legro RS

Aug 7th, 2021 - The goal of this Views and Reviews is to let colleagues and leaders well versed in the African American experience in reproductive medicine address the problems of racism affecting our trainees and patients and, more significantly, propose solutions. The areas in reproductive medicine that will be explored from the African American perspective include the pipeline of providers, health dispariti...