Journal of Obesity; Williams AG, Long M et. al.
Jan 31st, 2023 - The objective of this study was to functionally analyze the correlation of key histological features in brown adipose tissue (BAT) with clinical metabolic traits in nonhuman primates. Axillary adipose tissue biopsies were collected from a metabolically diverse nonhuman primate cohort with clinical metabolism-related data. Expression of tyrosine hydroxylase (TH), uncoupling protein 1 (UCP1), clu...
PloS One; Simon AM, Turner KL et. al.
Jan 27th, 2023 - Despite the growing availability of multifunctional prosthetic hands, users' control and overall functional abilities with these hands remain limited. The combination of pattern recognition control and targeted muscle reinnervation (TMR) surgery, an innovative technique where amputated nerves are transferred to reinnervate new muscle targets in the residual limb, has been used to improve prosth...
Physiological Reports; Smolilo DJ, Hibberd TJ et. al.
Jan 14th, 2023 - The speed of pellet propulsion through the isolated guinea pig distal colon in vitro significantly exceeds in vivo measurements, suggesting a role for inhibitory mechanisms from sources outside the gut. The aim of this study was to investigate the effects of sympathetic nerve stimulation on three different neurogenic motor behaviors of the distal colon: transient neural events (TNEs), colonic m...
ENeuro Merlet AN, Jéhannin P et. al.
Jan 13th, 2023 - Coordinating the four limbs is an important feature of terrestrial mammalian locomotion. When the foot dorsum contacts an obstacle, cutaneous mechanoreceptors send afferent signals to the spinal cord to elicit coordinated reflex responses in the four limbs to ensure dynamic balance and forward progression. To determine how the locomotor pattern of all four limbs changes in response to a sensory...
Anesthesiology Lanier WL
Jan 12th, 2023 - Cerebral Function and Muscle Afferent Activity Following Intravenous Succinylcholine in Dogs Anesthetized with Halothane: The Effects of Pretreatment with a Defasciculating Dose of Pancuronium. By WL Lanier, PA Iaizzo, and JH Milde. Anesthesiology 1989; 71:87-95. Reprinted with permission. By the mid-1980s, it was widely assumed that if the depolarizing muscle relaxant, succinylcholine, given I...
Advances in Experimental Medicine and Biology; Dent J, Dinning PG
Jan 1st, 2023 - This chapter reviews data on the pathways by which luminal, mainly duodenal, chemoreceptors modulate gastro-pyloro-duodenal motor function to control emptying of nutrients into the small intestine. The vagus mediates proximal gastric relaxation caused by nutrient stimulation of duodenal/jejunal mucosal chemoreceptors. Modulation of the spatial patterning and inhibition of antral contractions du...
Advances in Experimental Medicine and Biology; Vanden Berghe P, Fung C
Jan 1st, 2023 - The gastrointestinal tract operates in a highly dynamic environment. The gut is typically exposed to continually changing and highly convoluted luminal compositions comprising not only ingested content but also a multitude of resident microbes and microbial factors. It is therefore critical that the gut is capable of distinguishing between nutritious components from noxious substances. This is ...
Journal of Hypertension; Holwerda SW, Gangwish ME et. al.
Dec 31st, 2022 - Central (abdominal) obesity is associated with elevated adrenergic activity and arterial blood pressure (BP). Therefore, we tested the hypothesis that transduction of spontaneous muscle sympathetic nerve activity (MSNA) to BP, that is, sympathetic transduction, is augmented in abdominal obesity (increased waist circumference) and positively related to prevailing BP. Young/middle-aged obese (32 ...
Plastic and Reconstructive Surgery; Peters BR, Richards HW et. al.
Dec 29th, 2022 - One goal of an ideal phallic reconstruction is achieving tactile and erogenous sensation. Traditionally, the most common flap used in phalloplasty has been the radial forearm flap, where the medial and lateral antebrachial cutaneous nerves are coapted to meet this goal. The purpose of this article is to draw attention to the lesser-known posterior antebrachial cutaneous nerve (PABC) as an alter...
Plastic and Reconstructive Surgery; Teunis T
Dec 29th, 2022 - A Correlation between Upper Extremity Compressive Neuropathy and Nerve Compression Headache.|2022|Teunis T,|surgery,innervation,complications,diagnosis,
Plastic and Reconstructive Surgery; Gfrerer L, Austen WG
Dec 29th, 2022 - Reply: A Correlation between Upper Extremity Compressive Neuropathy and Nerve Compression Headache.|2022|Gfrerer L,Austen WG,|surgery,innervation,complications,diagnosis,
PloS One; Yunoki K, Watanabe T et. al.
Dec 23rd, 2022 - During submaximal isometric contraction, there are two different load types: maintenance of a constant limb angle while supporting an inertial load (position task) and maintenance of a constant force by pushing against a rigid restraint (force task). Previous studies demonstrated that performing the position task requires more proprioceptive information. The purpose of this study was to investi...
Annals of Plastic Surgery; Liu Q, Deng X et. al.
Dec 20th, 2022 - Anterior branch of the obturator nerve transfer has been proven as an effective method for femoral nerve injuries, but the patient still has difficulty in rising and squatting, up and downstairs. Here, we presented a novel neurotization procedure of selectively repairing 3 motor branches of the femoral nerve by transferring motor branches of the obturator nerve in the thigh level and assessing ...
Journal of Neurophysiology; Thakre PP, Rana S et. al.
Nov 24th, 2022 - Phrenic motoneurons (PhrMNs) innervate diaphragm myofibers. Located in the ventral gray matter (lamina IX), PhrMNs form a column extending from approximately the third to sixth cervical spinal segment. Phrenic motor output and diaphragm activation are impaired in many neuromuscular diseases, and targeted delivery of drugs and/or genetic material to PhrMNs may have therapeutic application. Studi...
Journal of Cardiothoracic and Vascular Anesthesia; Hargrave J, Grant MC et. al.
Nov 23rd, 2022 - The recent integration of regional anesthesia techniques into the cardiac surgical patient population has become a component of enhanced recovery after cardiac surgery pathways. Fascial planes of the chest wall enable single-injection or catheter-based infusions to spread local anesthetic over multiple levels of innervation. Although median sternotomy remains a common approach to cardiac surger...
Muscle & Nerve; Kang BH, Lee DW et. al.
Nov 11th, 2022 - Injuries to the dorsal scapular nerve (DSN) in the interscapular region are relatively uncommon. Physicians may therefore underestimate the risk of damage to the DSN during procedures. The aim of this study was to identify the topographic position of the DSN in the interscapular region and to identify injection positions for the upper extremities that minimize the risk of damage to the DSN duri...
Nature Kathe C, Skinnider MA et. al.
Nov 10th, 2022 - A spinal cord injury interrupts pathways from the brain and brainstem that project to the lumbar spinal cord, leading to paralysis. Here we show that spatiotemporal epidural electrical stimulation (EES) of the lumbar spinal cord1-3 applied during neurorehabilitation4,5 (EESREHAB) restored walking in nine individuals with chronic spinal cord injury. This recovery involved a reduction in neuronal...
PloS One; Kundu G, Shetty R et. al.
Nov 2nd, 2022 - To analyse various corneal nerve parameters using confocal microscopy along with systemic and orthoptic parameters in patients presenting with ocular surface pain using a random forest artificial intelligence (AI) model. Observational, cross-sectional. Two hundred forty eyes of 120 patients with primary symptom of ocular surface pain or discomfort and control group of 60 eyes of 31 patients wit...
Pain Physician; Knight M, Inklebarger J et. al.
Oct 27th, 2022 - Paravertebral cluneal nerves are constrained within a tunnel consisting of the thoracolumbar fascia and the iliac crest's superior rim as they pass over the iliac crest. Their involvement in low back pain has not been presented previously. To develop a diagnostic and therapeutic protocol for radiofrequency ablation of paravertebral and iliac cluneal trigger points. In a prospective observationa...
Surgical and Radiologic Anatomy : SRA; Saenz C, Rahimi OB et. al.
Oct 25th, 2022 - The purpose of this study is to characterize the division of the median nerve by the persistent median artery (PMA) and highlight the associated clinical implications. Penetration of the median nerve by the PMA is believed to cause compression of the median nerve and affect nerve conduction velocity. This paper explored whether the origin and the pattern of PMA dictate its ability to divide the...