×
About 283,114 results

Effect of Trans-Nasal Evaporative Intra-arrest Cooling on Functional Neurologic Outcome...
https://doi.org/10.1001/jama.2019.4149
JAMA Nordberg P, Taccone FS et. al.

May 7th, 2019 - Therapeutic hypothermia may increase survival with good neurologic outcome after cardiac arrest. Trans-nasal evaporative cooling is a method used to induce cooling, primarily of the brain, during cardiopulmonary resuscitation (ie, intra-arrest). To determine whether prehospital trans-nasal evaporative intra-arrest cooling improves survival with good neurologic outcome compared with cooling init...

A comparison of cosmetic outcomes of lacerations on the extremities and trunk using abs...
https://doi.org/10.1111/acem.12387
Academic Emergency Medicine : Official Journal of the Soc... Tejani C, Sivitz AB et. al.

Jul 21st, 2014 - The primary objective was to compare the cosmetic outcomes of traumatic trunk and extremity lacerations repaired using absorbable versus nonabsorbable sutures. The secondary objective was to compare complication rates between the two groups. This was a randomized controlled trial comparing wounds repaired with Vicryl Rapide and Prolene sutures. Pediatric and adult patients with lacerations were...

Continuous renal replacement therapy in neonates and small infants: development and fir...
https://doi.org/10.1016/S0140-6736(14)60799-6
Lancet (London, England); Ronco C, Garzotto F et. al.

May 26th, 2014 - Peritoneal dialysis is the renal replacement therapy of choice for acute kidney injury in neonates, but in some cases is not feasible or effective. Continuous renal replacement therapy (CRRT) machines are used off label in infants smaller than 15 kg and are not designed specifically for small infants. We aimed to design and create a CRRT machine specifically for neonates and small infants. We p...

Attention! A good bedside test for delirium?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173985
Journal of Neurology, Neurosurgery, and Psychiatry; O'Regan NA, Ryan DJ et. al.

Feb 26th, 2014 - Routine delirium screening could improve delirium detection, but it remains unclear as to which screening tool is most suitable. We tested the diagnostic accuracy of the following screening methods (either individually or in combination) in the detection of delirium: MOTYB (months of the year backwards); SSF (Spatial Span Forwards); evidence of subjective or objective 'confusion'. We performed ...

The effectiveness of cricoid pressure for occluding the esophageal entrance in anesthet...
https://doi.org/10.1213/ANE.0000000000000068
Anesthesia and Analgesia; Zeidan AM, Salem MR et. al.

Feb 21st, 2014 - In the last 2 decades, the effectiveness of cricoid pressure (CP) in occluding the esophageal entrance has been questioned. Recent magnetic resonance imaging studies yielded conflicting conclusions. We used real-time visual and mechanical means to assess the patency of the esophageal entrance with and without CP in anesthetized and paralyzed adult patients. One hundred seven, nonobese ASA physi...

Differential clinical outcomes after 1 year versus 5 years in a randomised comparison o...
https://doi.org/10.1016/S0140-6736(14)60405-0
Lancet (London, England); Maeng M, Tilsted HH et. al.

Mar 18th, 2014 - In head-to-head comparisons of coronary drug-eluting stents, the primary endpoint is traditionally assessed after 9-12 months. However, the optimum timepoint for this assessment remains unclear. In this study, we assessed clinical outcomes at up to 5 years' follow-up in patients who received two different types of drug-eluting stents. We undertook this multicentre, open-label, randomised superi...

Use of Electric Power Morcellation and Prevalence of Underlying Cancer in Women Who Und...
https://doi.org/10.1001/jamaoncol.2014.206
JAMA Oncology; Wright JD, Tergas AI et. al.

Jul 16th, 2015 - Myomectomy, the excision of uterine leiomyoma, is now commonly performed via minimally invasive surgery. Electric power morcellation, or fragmentation of the leiomyoma with a mechanical device, may be used to facilitate extraction of the leiomyoma. To analyze the prevalence of underlying cancer and precancerous changes in women who underwent myomectomy with and without electric power uterine mo...

Endovascular therapy for ischemic stroke with perfusion-imaging selection.
https://doi.org/10.1056/NEJMoa1414792
The New England Journal of Medicine; Campbell BC, Mitchell PJ et. al.

Feb 11th, 2015 - Trials of endovascular therapy for ischemic stroke have produced variable results. We conducted this study to test whether more advanced imaging selection, recently developed devices, and earlier intervention improve outcomes. We randomly assigned patients with ischemic stroke who were receiving 0.9 mg of alteplase per kilogram of body weight less than 4.5 hours after the onset of ischemic stro...

Randomized assessment of rapid endovascular treatment of ischemic stroke.
https://doi.org/10.1056/NEJMoa1414905
The New England Journal of Medicine; Goyal M, Demchuk AM et. al.

Feb 11th, 2015 - Among patients with a proximal vessel occlusion in the anterior circulation, 60 to 80% of patients die within 90 days after stroke onset or do not regain functional independence despite alteplase treatment. We evaluated rapid endovascular treatment in addition to standard care in patients with acute ischemic stroke with a small infarct core, a proximal intracranial arterial occlusion, and moder...

Handheld echocardiography versus auscultation for detection of rheumatic heart disease.
https://doi.org/10.1542/peds.2014-2774
Pediatrics Godown J, Lu JC et. al.

Mar 17th, 2015 - Rheumatic heart disease (RHD) remains a major public health concern in developing countries, and routine screening has the potential to improve outcomes. Standard portable echocardiography (STAND) is far more sensitive than auscultation for the detection of RHD but remains cost-prohibitive in resource-limited settings. Handheld echocardiography (HAND) is a lower-cost alternative. The purpose of...

Color-Coded Prefilled Medication Syringes Decrease Time to Delivery and Dosing Error in...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872869
Annals of Emergency Medicine; Moreira ME, Hernandez C et. al.

Feb 23rd, 2015 - The Institute of Medicine has called on the US health care system to identify and reduce medical errors. Unfortunately, medication dosing errors remain commonplace and may result in potentially life-threatening outcomes, particularly for pediatric patients when dosing requires weight-based calculations. Novel medication delivery systems that may reduce dosing errors resonate with national healt...

Endotracheal intubation versus supraglottic airway placement in out-of-hospital cardiac...
https://doi.org/10.1016/j.resuscitation.2015.05.007
Resuscitation Benoit JL, Gerecht RB et. al.

May 26th, 2015 - Overall survival from out-of-hospital cardiac arrest (OHCA) is less than 10%. After initial bag-valve mask ventilation, 80% of patients receive an advanced airway, either by endotracheal intubation (ETI) or placement of a supraglottic airway (SGA). The objective of this meta-analysis was to compare patient outcomes for these two advanced airway methods in OHCA patients treated by Emergency Medi...

Thrombectomy within 8 hours after symptom onset in ischemic stroke.
https://doi.org/10.1056/NEJMoa1503780
The New England Journal of Medicine; Jovin TG, Chamorro A et. al.

Apr 17th, 2015 - We aimed to assess the safety and efficacy of thrombectomy for the treatment of stroke in a trial embedded within a population-based stroke reperfusion registry. During a 2-year period at four centers in Catalonia, Spain, we randomly assigned 206 patients who could be treated within 8 hours after the onset of symptoms of acute ischemic stroke to receive either medical therapy (including intrave...

Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke.
https://doi.org/10.1056/NEJMoa1415061
The New England Journal of Medicine; Saver JL, Goyal M et. al.

Apr 17th, 2015 - Among patients with acute ischemic stroke due to occlusions in the proximal anterior intracranial circulation, less than 40% regain functional independence when treated with intravenous tissue plasminogen activator (t-PA) alone. Thrombectomy with the use of a stent retriever, in addition to intravenous t-PA, increases reperfusion rates and may improve long-term functional outcome. We randomly a...

The use of a video laryngoscope by emergency medicine residents is associated with a re...
https://doi.org/10.1111/acem.12674
Academic Emergency Medicine : Official Journal of the Soc... Sakles JC, Javedani PP et. al.

May 22nd, 2015 - The purpose of this investigation was to compare the incidence of esophageal intubations (EIs) when emergency medicine (EM) residents used a direct laryngoscope (DL) versus a video laryngoscope (VL) for intubation attempts in the emergency department (ED). Prospectively collected continuous quality improvement data on tracheal intubations performed by EM residents in an academic ED over a 6-yea...

Ex-vivo perfusion of donor hearts for human heart transplantation (PROCEED II): a prosp...
https://doi.org/10.1016/S0140-6736(15)60261-6
Lancet (London, England); Ardehali A, Esmailian F et. al.

Apr 18th, 2015 - The Organ Care System is the only clinical platform for ex-vivo perfusion of human donor hearts. The system preserves the donor heart in a warm beating state during transport from the donor hospital to the recipient hospital. We aimed to assess the clinical outcomes of the Organ Care System compared with standard cold storage of human donor hearts for transplantation. We did this prospective, o...

High-Flow Nasal Oxygen vs Noninvasive Positive Airway Pressure in Hypoxemic Patients Af...
https://doi.org/10.1001/jama.2015.5213
JAMA Stéphan F, Barrucand B et. al.

May 19th, 2015 - Noninvasive ventilation delivered as bilevel positive airway pressure (BiPAP) is often used to avoid reintubation and improve outcomes of patients with hypoxemia after cardiothoracic surgery. High-flow nasal oxygen therapy is increasingly used to improve oxygenation because of its ease of implementation, tolerance, and clinical effectiveness. To determine whether high-flow nasal oxygen therapy ...

Conventional Versus Video Laryngoscopy for Tracheal Tube Exchange: Glottic Visualizatio...
https://doi.org/10.1213/ANE.0000000000000825
Anesthesia and Analgesia; Mort TC, Braffett BH

Jun 25th, 2015 - Tracheal tube exchange is a simple concept but not a simple procedure because hypoxemia, esophageal intubation, and loss of airway may occur with life-threatening ramifications. Combining laryngoscopy with an airway exchange catheter (AEC) may lessen the exchange risk. Laryngoscopy is useful for a pre-exchange examination and to open a pathway for endotracheal tube (ETT) passage. Direct laryngo...

Trial of a Paclitaxel-Coated Balloon for Femoropopliteal Artery Disease.
https://doi.org/10.1056/NEJMoa1406235
The New England Journal of Medicine; Rosenfield K, Jaff MR et. al.

Jun 24th, 2015 - The treatment of peripheral artery disease with percutaneous transluminal angioplasty is limited by the occurrence of vessel recoil and restenosis. Drug-coated angioplasty balloons deliver antiproliferative agents directly to the artery, potentially improving vessel patency by reducing restenosis. In this single-blind, randomized trial conducted at 54 sites, we assigned, in a 2:1 ratio, 476 pat...

Robotic Mitral Valve Repair for Simple and Complex Degenerative Disease: Midterm Clinic...
https://doi.org/10.1161/CIRCULATIONAHA.115.017792
Circulation Suri RM, Taggarse A et. al.

Oct 20th, 2015 - Severe primary (degenerative) mitral regurgitation (MR) is repaired with durable results when simple single-scallop disease is addressed. The midterm quality outcomes of minimally invasive repair for complex disease are unknown, however. From January 2008 to January 2015, 487 patients (56±11 years, 360 men, ejection fraction 65±6%, 98.8% complete follow-up) underwent robotic mitral valve repair...