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About 53,353 results

The difference in the effectiveness of human papillomavirus vaccine based on smoking st...
https://doi.org/10.1111/jog.15270
The Journal of Obstetrics and Gynaecology Research; Hikari T, Honda A et. al.

May 24th, 2022 - This study aimed to clarify (1) the effectiveness of human papillomavirus (HPV) vaccine against precancerous lesions of uterine cervical cancer and (2) the difference in these effectiveness based on smoking status. This retrospective cross-sectional study considered women aged 20-24 who underwent cervical cancer screening in Saga City from April 2014 to March 2020. Cervical cytology and histolo...

A colorectal cancer missed by colon capsule endoscopy: a case report.
https://doi.org/10.1186/s12876-022-02332-8 10.5946/ce.2019.213 10.1016/S2468-1253(18)30032-3 10.1186/s12916-020-01717-4
BMC Gastroenterology; MacLeod C, Oliphant R et. al.

May 22nd, 2022 - Colon capsule endoscopy (CCE) is a non-invasive alternative to colonoscopy. The reported sensitivity and specificity of CCE for the detection of clinically significant colonic neoplasia is high. To date, there have been no reported cases of colorectal cancer (CRC) missed by CCE which were located in segments adequately visualised by the capsule. We present the case of a 71-year-old female, who ...

Optical biopsy for esophageal squamous cell neoplasia by using endocytoscopy.
https://doi.org/10.1186/s12876-022-02335-5 10.1111/jgh.12477 10.1038/ajg.2014.94 10.1055/s-0035-1569644 10.1055/s-2006-944667 10.1111/j.1442-2050.2011.01241.x 10.1136/gut.47.2.251 10.1007/s10388-016-0551-7 10.1136/gut.51.1.130 10.1016/j.gie.2005.09.027 10.1055/s-0032-1325932 10.1111/den.12601 10.1055/a-1068-9228 10.1053/j.gastro.2016.07.040 10.1038/s41598-020-76309-6 10.1159/000506930 10.21037/tgh.2019.11.12 10.1002/1097-0142(19950915)76:6<928::AID-CNCR2820760604>3.0.CO;2-5 10.1186/1471-230X-14-141 10.1111/j.1440-1746.2009.06032.x 10.1097/CM9.0000000000000623 10.1016/j.gie.2018.07.037 10.1016/j.gie.2018.11.011 10.1053/j.gastro.2018.06.037 10.1053/j.gastro.2016.04.004 10.1055/s-0042-113609 10.1007/s10388-018-0651-7
BMC Gastroenterology; Shimoda Y, Shimizu Y et. al.

May 22nd, 2022 - Endocytoscopy (ECS) enables microscopic observation in vivo for the gastrointestinal mucosa; however, there has been no prospective study in which the diagnostic accuracy of ECS for lesions that have not yet undergone histological diagnosis was evaluated. We conducted a surveillance study for patients in a high-risk group of esophageal squamous cell carcinoma (ESCC) and evaluated the in vivo hi...

Intestinal Cancer and Dysplasia in Crohn's Disease.
https://doi.org/10.1016/j.gtc.2021.12.011
Gastroenterology Clinics of North America; Friedberg S, Rubin DT

May 21st, 2022 - Crohn's disease is associated with an increased risk of adenocarcinoma of the involved portions of the small bowel and colorectum and has similar risk factors to those described in ulcerative colitis, most significantly, extent of bowel involvement, PSC, and duration of unresected disease. Prevention strategies include risk stratification and secondary prevention with colonoscopic screening and...

Dye-based chromoendoscopy for the detection of colorectal neoplasia: meta-analysis of r...
https://doi.org/10.1016/j.gie.2022.05.002
Gastrointestinal Endoscopy; Antonelli G, Correale L et. al.

May 20th, 2022 - Dye-Based chromoendoscopy (DBC) could be effective in increasing adenoma detection rate (ADR) in patients undergoing colonoscopy, but the technique is time-consuming and its uptake is limited. We aimed to assess the effect of DBC on ADR based on available randomized controlled trials (RCTs). Four databases were searched up to April 2022, for RCTs comparing DBC with conventional colonoscopy (CC)...

Koala retrovirus load and non-A subtypes are associated with secondary disease among wi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119473
PLoS Pathogens; Blyton MDJ, Pyne M et. al.

May 20th, 2022 - Koala Retrovirus (KoRV) has been associated with neoplasia in the vulnerable koala (Phascolarctos cinereus). However, there are conflicting findings regarding its association with secondary disease. We undertook a large-scale assessment of how the different KoRV subtypes and viral load are associated with Chlamydia pecorum infection and a range of disease pathologies in 151 wild koalas admitted...

One-sample quantitative and two-sample qualitative faecal immunochemical tests for colo...
https://doi.org/10.1136/bmjopen-2021-059754
BMJ Open; Wang L, Chen H et. al.

May 20th, 2022 - Quantitative faecal immunochemical tests (FITs) are widely used for colorectal cancer (CRC) screening in the Western countries, whereas qualitative FITs are preferred in China. The present study aimed to compare the screening yield between one-sample quantitative FIT and two-sample qualitative FIT for CRC screening. A cross-sectional study. A population-based CRC screening programme was conduct...

Superficial spreading cervical squamous cell carcinoma in situ involving the endometriu...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9121615
Journal of Medical Case Reports; Martín-Vallejo J, Laforga JB et. al.

May 20th, 2022 - The spread of cervical squamous cell carcinoma to the inner surface of the uterus with replacement of the endometrium is rare. Continuity of the lesion must be demonstrated to confirm superficial spread and rule out concomitant endometrial cancer. We present the case of a 66-year-old white woman with superficial spreading squamous cell carcinoma of the cervix that involved the endometrium. Her ...

Multidisciplinary integrated care pathway for von Hippel-Lindau disease.
https://doi.org/10.1002/cncr.34265
Cancer Wolters WPG, Dreijerink KMA et. al.

May 18th, 2022 - Clinical pathways are care plans established to describe essential steps in the care of patients with a specific clinical problem. They translate (inter)national guidelines into local applicable protocols and clinical practice. The purpose of this article is to establish a multidisciplinary integrated care pathway for specialists and allied health care professionals in caring for individuals wi...

Recurrent ipsilateral pheochromocytoma in carriers of RET p.Cys634 missense mutations.
https://doi.org/10.1007/s12020-022-03073-0 10.1089/thy.2014.0335 10.1016/j.beem.2019.04.008 10.1530/EJE-21-0753 10.1056/NEJMoa012915 10.1002/humu.23430 10.1210/jc.2012-3192 10.1111/cen.13386 10.1002/bjs.10746 10.1677/ERC-10-0211 10.1067/msy.2001.118373 10.1007/978-3-642-84749-3_9 10.1016/j.surg.2003.08.005 10.1016/j.jamcollsurg.2003.12.001 10.1016/j.jamcollsurg.2012.10.012 10.1080/01621459.1958.10501452 10.1038/bjc.1977.1 10.1016/S1470-2045(14)70154-8 10.1001/jamanetworkopen.2019.8898 10.1001/jama.1996.03540190047028 10.1111/cen.12978 10.1002/1096-9896(2000)9999:9999<::AID-PATH679>3.0.CO;2-B
Endocrine Machens A, Lorenz K et. al.

May 18th, 2022 - The objective of this study was to provide RET genotype-specific data on recurrent ipsilateral pheochromocytoma in multiple endocrine neoplasia type 2A (MEN2A), which are sparse. Kaplan-Meier analyses were performed to determine the risk of recurrent ipsilateral adrenalectomy after subtotal and total adrenalectomy in 221 carriers of RET p.Cys634 missense mutations. Altogether, pheochromocytoma ...

Pathophysiology and Clinical Management of Autoimmune Encephalitis-Associated Seizures.
https://doi.org/10.1159/000524783
Neuroimmunomodulation Zhu S, Yu J et. al.

May 18th, 2022 - Seizures are a very common manifestation of autoimmune encephalitis (AE), ranging from 33% to 100% depending on the antigen, most often accompanied by other clinical features such as behavioral changes, movement disorders, memory deficits, autoimmune disturbances, and altered levels of consciousness. Unusual seizure frequency, resistance to antiepileptic treatment, and often, definitive respons...

Impact of the COVID-19 pandemic on fecal immunochemical testing, colonoscopy services, ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9107101
Gastroenterology Lee JK, Lam AY et. al.

May 18th, 2022 - The COVID-19 pandemic has impacted clinical services globally, including colorectal cancer (CRC) screening and diagnostic testing. We investigated the pandemic's impact on fecal immunochemical test (FIT) screening, colonoscopy utilization, and colorectal neoplasia detection across 21 medical centers in a large integrated healthcare organization. We performed a retrospective cohort study in Kais...

Clinical validation of full HR-HPV genotyping HPV Selfy assay according to the internat...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115952
Journal of Translational Medicine; Avian A, Clemente N et. al.

May 18th, 2022 - According to international guidelines, Human Papillomavirus (HPV) DNA tests represent a valid alternative to Pap Test for primary cervical cancer screening, provided that they guarantee balanced clinical sensitivity and specificity for cervical intraepithelial neoplasia grade 2 or more (CIN2+) lesions. The study aimed to assess whether HPV Selfy (Ulisse BioMed - Trieste, Italy), a full-genotypi...

Clinical features and postoperative survival in patients with sporadic versus multiple ...
https://doi.org/10.1016/j.surg.2022.04.011
Surgery Bergquist JR, Shariq OA et. al.

May 17th, 2022 - The optimal surgical management of pancreatic neuroendocrine tumors in patients with multiple endocrine neoplasia type 1 is controversial. This study sought to compare clinicopathologic characteristics and outcomes of multiple endocrine neoplasia type 1-associated and sporadic pancreatic neuroendocrine tumors from a large multi-national database. A multi-institutional, international database of...

HPV Vaccination: Does It Have a Role in Preventing Penile Cancer and Other Preneoplasti...
https://doi.org/10.1016/j.soncn.2022.151284
Seminars in Oncology Nursing; Elst L, Albersen M

May 17th, 2022 - Human papillomavirus (HPV) is the most common sexually transmitted infection globally, which causes nearly all cervix carcinomas and contributes to oropharyngeal, penile, vulva, vagina, and anal cancers. Despite the role of HPV in several preneoplastic and cancerous lesions in men, male vaccine coverage is low. This article aims to provide insights into the pathophysiology of HPV-related penile...

Gastrointestinal neoplasia: carcinogenic interaction between bile acids and Helicobacte...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106340
The Journal of Clinical Investigation; Alizadeh M, Raufman JP

May 17th, 2022 - Bile acids modulate cell functions in health and disease, however, the mechanisms underlying their actions on neoplastic cells in the gastrointestinal (GI) tract remain largely unknown. In this issue of the JCI, Noto et al. comprehensively analyzed how interactions between Helicobacter pylori infection, iron deficiency, and bile acids modulate gastric inflammation and carcinogenesis. The invest...

Evaluation of effectiveness, acceptability, and safety of thermal ablation in the treat...
https://doi.org/10.1002/ijc.34117
International Journal of Cancer; Sauvaget C, Bazikamwe S et. al.

May 15th, 2022 - This longitudinal study aimed at evaluating the effectiveness, acceptability, and safety of the thermal ablation procedure (TA) in the treatment of cervical neoplasia. Women referred to the Gynaecology ward for symptoms or for opportunistic screening were assessed by visual inspection with acetic acid (VIA) and colposcopy. Those with lesions eligible to ablation were counselled and treated by T...

Genotype-Phenotype Correlations in Asian Indian Children and Adolescents with Primary H...
https://doi.org/10.1007/s00223-022-00985-x 10.1159/000381622 10.1530/EJE-20-1119 10.1111/cen.13453 10.1038/nrdp.2016.33 10.1210/jc.2014-3659 10.1007/s12020-017-1322-5 10.1210/endrev/bnaa031 10.1210/jc.2017-01249 10.1210/jc.2008-2430 10.1111/j.1365-2265.2011.04059.x 10.1210/jc.2018-02789 10.1210/jc.2014-2000 10.11138/ccmbm/2017.14.1.060 10.1055/s-0030-1255106 10.1111/cen.14254 10.1053/j.ajkd.2008.11.017 10.1136/gutjnl-2012-302779 10.1086/301953 10.1210/jcem.83.3.4653 10.1093/hmg/6.7.1169 10.1111/j.1365-2265.2011.04184.x 10.1210/jc.2012-2789 10.1038/ng.2007.44 10.1056/NEJMoa031237 10.1016/j.ando.2009.09.004 10.4103/ijem.IJEM_53_20 10.1007/s12098-014-1442-3 10.4103/2230-8210.202034 10.4103/ijem.ijem_349_21 10.1007/s10689-016-9891-7 10.1055/a-1402-0183 10.1002/humu.21188 10.1002/path.1489 10.1038/ng1295-389 10.1111/cen.14211 10.1111/j.1365-2265.2010.03870.x 10.1210/jc.2004-1046 10.1046/j.1365-2265.1999.00729.x 10.1210/jcem.80.9.7673400 10.1210/jc.2008-2484 10.1210/jc.2013-3593 10.1002/ccr3.1074 10.1007/s40618-017-0710-2 10.1055/s-0034-1372058 10.1111/j.1440-1746.2011.06791.x
Calcified Tissue International; Sharma A, Memon S et. al.

May 15th, 2022 - Childhood and adolescent primary hyperparathyroidism (PHPT) is a very rare disease. Data on its molecular genetics are scarce. We performed a retrospective analysis (January 2000-January 2021) to determine the deleterious germline variants and genotype-phenotype correlations in children and adolescents < 20 years diagnosed with PHPT from a single referral center. Clinical features, biochemistry...

BENEFIT OF EXTENDED SURVEILLANCE OF LOW-RISK PANCREATIC CYSTS AFTER FIVE-YEAR STABILITY...
https://doi.org/10.1016/j.cgh.2022.04.025
Clinical Gastroenterology and Hepatology : the Official C... Chhoda A, Singh S et. al.

May 15th, 2022 - Low-risk branch duct intraductal papillary mucinous neoplasms (BD-IPMN lacking worrisome features (WF) and high-risk stigmata (HRS)), warrant surveillance. However, their optimal duration, especially among cysts with initial five years of size stability, warrants further investigation. We aim to systematically review the surveillance of low-risk BD-IPMNs and investigate incidence of WF/HRS and ...

Self-Shielding Gyroscopic Radiosurgery - A First Clinical Experience, Case Series, and ...
https://doi.org/10.1016/j.wneu.2022.04.120
World Neurosurgery; Muacevic A, Eder MM et. al.

May 15th, 2022 - Self-shielding gyroscopic radiosurgery (GRS) represents a technical innovation in the field of stereotactic radiosurgery (SRS). GRS does not require a radiation vault and is optimized for radiosurgical treatments. Reports on its usage are limited. We describe the first clinical experience of GRS at our institution to assess the application of GRS in the treatment of cranial tumors. Moreover, we...