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About 2,674,820 results

First analyses of lysine succinylation proteome and overlap between succinylation and a...
https://doi.org/10.1186/s12864-021-08285-8 10.1016/j.celrep.2013.07.024 10.1016/j.isci.2018.03.012 10.1016/j.cmet.2017.03.006 10.1038/nchembio.495 10.1016/j.molcel.2013.06.001 10.1038/s41438-019-0216-5 10.1021/acs.jproteome.9b00462 10.1038/s41598-018-36852-9 10.1038/srep31576 10.1021/acs.jproteome.8b00210 10.1371/journal.ppat.1007942 10.1016/0091-6749(94)90376-X 10.1126/science.265.5179.1744 10.1371/journal.pone.0243787 10.1093/nar/28.1.27 10.1002/pro.3715 10.1093/nar/gkaa970 10.1021/pr500992r 10.1080/10409230490440541 10.1007/s12031-016-0867-8 10.1007/s00424-003-1192-y 10.1016/0091-6749(93)90298-T 10.1016/j.jaci.2004.04.016 10.1523/JNEUROSCI.1899-04.2004 10.1523/JNEUROSCI.1899-04.2004 10.1126/science.1175371 10.1023/A:1006129220778 10.1046/j.1432-1033.2003.03946.x 10.1016/S0022-1910(99)00202-4 10.1093/protein/6.1.101 10.1007/s005350200065
BMC Genomics; Ye J, Li J

Jan 19th, 2022 - Lysine succinylation (Ksu) exists in both eukaryotes and prokaryotes, and influences a variety of metabolism processes. However, little attention has been paid to Ksu in insects, especially the notorious invasive pest Solenopsis invicta. In this study, the first analyses of Ksu proteome and overlap between Ksu and lysine acetylation (Kac) in S. invicta were presented. 3753 succinylated sites in...

Alpha-synuclein and cortico-striatal plasticity in animal models of Parkinson disease.
https://doi.org/10.1016/B978-0-12-819410-2.00008-4
Handbook of Clinical Neurology; Marino G, Calabresi P et. al.

Jan 18th, 2022 - Alpha-synuclein (α-synuclein) is a small, acidic protein containing 140 amino acids, highly expressed in the brain and primarily localized in the presynaptic terminals. It is found in high concentrations in Lewy Bodies, proteinaceous aggregates that constitute a typical histopathologic hallmark of Parkinson's disease. Altered environmental conditions, genetic mutations and post-translational ch...

Synaptic dysfunction in early phases of Alzheimer's Disease.
https://doi.org/10.1016/B978-0-12-819410-2.00022-9
Handbook of Clinical Neurology; Pelucchi S, Gardoni F et. al.

Jan 18th, 2022 - The synapse is the locus of plasticity where short-term alterations in synaptic strength are converted to long-lasting memories. In addition to the presynaptic terminal and the postsynaptic compartment, a more holistic view of the synapse includes the astrocytes and the extracellular matrix to form a tetrapartite synapse. All these four elements contribute to synapse health and are crucial for ...

Insulin sensitizes neural and vascular TRPV1 receptors in the trigeminovascular system.
https://doi.org/10.1186/s10194-021-01380-x 10.1172/JCI13020 10.2337/diacare.13.6.565 10.1016/j.jcjd.2016.07.002 10.2337/diacare.27.3.781 10.1007/s10194-012-0416-y 10.1111/j.1468-2982.2005.00928.x 10.1007/s10072-012-1046-5 10.1016/j.mehy.2016.10.029 10.1016/S1474-4422(19)30185-1 10.1177/0333102418771350 10.1113/jphysiol.2003.050633 10.1007/s00424-012-1142-7 10.4324/9781315152837-8 10.1177/0333102416654883 10.1016/j.pain.2013.07.021 10.1523/JNEUROSCI.0373-15.2015 10.1038/272827a0 10.1046/j.1529-8027.2002.02005.x 10.1002/cne.21389 10.1097/MPA.0000000000000959 10.1046/j.1460-9568.2003.03004.x 10.1016/j.pain.2009.08.002 10.1186/1744-8069-1-17 10.3390/ijms161024353 10.1016/j.cell.2018.11.049 10.1016/j.pharmthera.2020.107528 10.1146/annurev-pharmtox-010814-124701 10.1111/head.13033 10.4103/0976-500X.119726 10.1007/s10194-009-0139-x 10.1111/j.1476-5381.1995.tb13361.x 10.1371/journal.pone.0078184 10.1186/1129-2377-14-71 10.1177/0333102418786261 10.1111/joa.12529 10.1016/j.semcdb.2006.09.004 10.1016/s0896-6273(00)80564-4 10.1007/s11064-008-9750-5 10.1051/rnd:19890603 10.1016/S0021-9258(18)54996-6 10.1210/endo.136.9.7649094 10.1111/dom.12501 10.1155/2016/9270768 10.1016/0304-3940(85)90201-0 10.1124/mol.65.6.1352 10.1096/fj.201902026R 10.1046/j.0953-816x.2001.01741.x 10.1152/jn.01293.2005 10.1038/sj.bjp.0701779 10.1186/s10194-016-0644-7 10.1111/j.1476-5381.2011.01645.x 10.2310/JIM.0b013e3182746f95 10.1006/geno.2001.6647 10.1002/ajmg.b.30560 10.1186/s10194-018-0848-0
The Journal of Headache and Pain; Rosta J, Tóth M et. al.

Jan 17th, 2022 - Clinical observations suggest that hyperinsulinemia and insulin resistance can be associated with migraine headache. In the present study we examined the effect of insulin on transient receptor potential vanilloid 1 (TRPV1) receptor-dependent meningeal nociceptor functions in rats. The effects of insulin on the TRPV1 receptor stimulation-induced release of calcitonin gene related peptide (CGRP)...

Degradome comparison between wild and cultivated rice identifies differential targeting...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759253
BMC Genomics; Swetha C, Narjala A et. al.

Jan 16th, 2022 - Small non-coding (s)RNAs are involved in the negative regulation of gene expression, playing critical roles in genome integrity, development and metabolic pathways. Targeting of RNAs by ribonucleoprotein complexes of sRNAs bound to Argonaute (AGO) proteins results in cleaved RNAs having precise and predictable 5` ends. While tools to study sliced bits of RNAs to confirm the efficiency of sRNA-m...

Design of a Long-Acting Rivastigmine Transdermal Delivery System: Based on Computationa...
https://doi.org/10.1208/s12249-021-02207-3 10.1002/med.21434 10.1007/s40266-016-0405-y 10.1016/j.xphs.2020.12.024 10.1016/S1773-2247(14)50041-X 10.1016/S1461-5347(00)00295-9 10.1517/17425255.2015.1063615 10.1016/j.ijpharm.2020.119737 10.3390/pharmaceutics11040173 10.1007/s40204-019-0114-9 10.1021/acs.molpharmaceut.0c01054 10.1016/j.xphs.2017.03.003 10.1016/j.ejpb.2018.02.032 10.1016/j.ijpharm.2021.120560 10.1016/j.chemphyslip.2019.104794 10.1016/j.ijpharm.2021.120503 10.1016/j.apsb.2019.11.014 10.1080/03639045.2018.1483391 10.1208/s12249-021-02055-1 10.1016/j.jconrel.2015.05.263 10.1016/S0169-409X(01)00113-2 10.1038/sj.clpt.6100242 10.1016/S0939-6411(02)00051-6 10.3109/10717544.2014.889778 10.1016/j.ijpharm.2021.120560 10.1016/j.jconrel.2016.02.027 10.1016/j.ejps.2021.105783 10.1016/j.ejps.2019.105009 10.1208/s12249-012-9900-6
AAPS PharmSciTech; Han X, Liu J et. al.

Jan 15th, 2022 - The purpose of our study was using a computational simulation to develop a long-acting patch of rivastigmine (RVS). A range of patch formulations were screened including pressure sensitive adhesive (PSA), pharmaceutical excipients, and controlled release membranes using transfer simulation based on a mathematical model. Diffusion dynamics parameters for simulated operations were acquired throug...

Regulation of Antioxidant Enzyme Levels in Rat Brain.
https://doi.org/10.1007/978-3-030-78787-5_3 10.1034/j.1600-0404.2002.01238.x 10.1016/S0009-8981(00)00337-5 10.3349/ymj.1993.34.1.1 10.1111/j.1528-1157.1998.tb01367.x 10.1023/B:NERE.0000035811.06277.b3 10.1071/9780643100978 10.1016/0006-291X(76)90747-6 10.1111/j.1432-1033.1974.tb03714.x 10.1016/B978-0-12-395630-9.50158-4 10.1016/S1367-5931(99)80035-0 10.1016/S0197-0186(02)00070-0 10.1016/S0006-8993(99)02084-3 10.1111/j.1471-4159.1992.tb10990.x 10.1111/j.1432-1033.1993.tb18025.x 10.1007/s00702-007-0805-6 10.1248/bpb.22.1177
Advances in Experimental Medicine and Biology; Guggilla S, Karthik M et. al.

Jan 14th, 2022 - The whole plant of Nasturtium microphyllum is used as traditional Indian medicine to treat epilepsy. Previous studies have demonstrated that extracts of these plants were subjected to acute toxicity and then screened for antiepileptic activity on maximal electroshock (MES)- and pentylenetetrazole (PTZ)-induced seizure models in albino Wistar rats. The purpose of the present study is to investig...

Synthesis, Anti-inflammatory Activity, and In Silico Studies of Some New 3-({P-Dimethyl...
https://doi.org/10.1007/978-3-030-78787-5_43 10.1002/prac.18410240101 10.1002/prac.18420250155 10.1002/anie.198811133 10.1192/bjp.109.462.687 10.1016/S0014-827X(99)00075-0 10.1016/S0968-0896(02)00439-X 10.1016/j.antiviral.2006.02.010 10.1002/ardp.201100055 10.1016/j.ejmech.2009.12.035 10.1080/14756366.2017.1279155 10.5530/ijper.52.1.13 10.1016/j.bmcl.2004.05.025 10.5897/AJPP2014.4261 10.1016/j.ejmech.2008.02.034 10.17344/acsi.2017.3575 10.1021/jm051256o 10.1155/2015/826489 10.1016/j.molstruc.2017.09.092
Advances in Experimental Medicine and Biology; Swathi K, Chaitanya M et. al.

Jan 14th, 2022 - Ten novel isatin Schiff base analogs have been designed using a combination of isatin, hydrazine hydrate, and para-dimethylaminobenzaldehyde. Molecular docking studies have been performed to study the binding interactions of the designed compounds with COX-2 protein as a target (PDB code: 3LN1). The ten novel 3-({p-dimethylamino}benzylidenehydrazinylidene)-1,3-dihydro-2H-indole-2-one derivative...

Liposomes: Production Methods and Application in Alzheimer's Disease.
https://doi.org/10.1007/978-3-030-78787-5_48 10.1007/978-981-10-0791-0
Advances in Experimental Medicine and Biology; Naziris N, Demetzos C

Jan 14th, 2022 - Liposomes and lipidic vehicles are nanotechnological platforms that are present in the clinic and industry, with extensive application and much potential in the field of therapeutics. Currently, the obstacles associated with the pathology and physiology of Alzheimer's disease (AD) and neurodegenerative disorders (NDDs) in general have rendered it impossible to find an effective therapy for thes...

Identification of cardiomyopathy-related core genes through human metabolic networks an...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753885
BMC Genomics; Rong Z, Chen H et. al.

Jan 13th, 2022 - Cardiomyopathy is a complex type of myocardial disease, and its incidence has increased significantly in recent years. Dilated cardiomyopathy (DCM) and ischemic cardiomyopathy (ICM) are two common and indistinguishable types of cardiomyopathy. Here, a systematic multi-omics integration approach was proposed to identify cardiomyopathy-related core genes that could distinguish normal, DCM and ICM...

Bioengineering for the industrial production of 2,3-butanediol by the yeast, Saccharomy...
https://doi.org/10.1007/s11274-021-03224-x 10.1016/0168-1656(93)90094-4 10.1007/s10295-008-0501-z 10.1007/s11274-016-2161-x 10.1016/j.biotechadv.2009.05.002 10.1016/j.biotechadv.2013.02.009 10.1371/journal.pone.0138109 10.1016/j.procbio.2015.11.023 10.1111/j.1574-6968.1999.tb13551.x 10.1002/bit.25265 10.1186/s13068-016-0502-5 10.1021/ie50283a019 10.1016/j.jbiosc.2015.11.002 10.1016/0960-8524(94)00136-O 10.4236/jbnb.2011.23041 10.1039/C6GC01023G 10.1186/1754-6834-7-44 10.1021/acssuschemeng.8b03414 10.1016/j.bej.2018.09.002 10.1016/j.btre.2019.e00397 10.1186/s13068-018-1013-3 10.1016/j.tibtech.2007.01.001 10.1016/j.biortech.2020.122873 10.1016/j.ymben.2005.12.003 10.1016/j.ymben.2015.04.004 10.1016/j.jbiosc.2013.09.007 10.1016/j.biotechadv.2011.01.007 10.1016/j.procbio.2008.09.019 10.1007/s00253-013-4981-z 10.1007/s00253-003-1537-7 10.1016/j.ymben.2015.07.006 10.4014/jmb.1201.01044 10.1016/j.biortech.2013.07.081 10.1016/j.biortech.2015.02.077 10.1186/s13068-016-0677-9 10.1007/s00253-017-8172-1 10.1016/0141-0229(86)90147-X 10.1186/s13068-019-1545-1 10.1016/j.jbiotec.2015.06.385 10.1016/j.cep.2020.108286 10.1016/j.procbio.2010.01.011 10.1007/s00253-010-2676-2 10.1016/j.ymben.2014.02.003 10.1007/s00253-010-2594-3 10.1007/s00253-008-1732-7 10.1089/omi.2010.0072 10.1007/s12010-019-03040-y 10.1016/j.jbiosc.2020.11.004 10.1016/S1389-1723(00)90013-6 10.1186/1475-2859-11-68 10.1002/biot.201800421 10.1002/biot.200900279 10.1186/1475-2859-11-131 10.1007/s00253-009-2004-x 10.1002/(SICI)1097-0061(199612)12:16<1607::AID-YEA70>3.0.CO;2-4 10.1080/01496399408002168 10.1016/0141-0229(87)90152-9 10.1073/pnas.0730845100 10.1016/j.memsci.2008.12.033 10.4014/jmb.1302.02066 10.1128/AEM.01616-10 10.1016/S0922-338X(97)82052-1 10.1016/j.biortech.2013.10.101 10.1371/journal.pone.0008860 10.1007/s00253-008-1387-4 10.1016/j.biortech.2017.05.034 10.1007/s10295-018-2033-5 10.1002/jobm.201100033 10.1371/journal.pone.0076149 10.1002/bbb.2081 10.1007/BF00172538 10.1007/BF00164519
World Journal of Microbiology & Biotechnology; Mitsui R, Yamada R et. al.

Jan 13th, 2022 - Owing to issues, such as the depletion of petroleum resources and price instability, the development of biorefinery related technologies that produce fuels, electric power, chemical substances, among others, from renewable resources is being actively promoted. 2,3-Butanediol (2,3-BDO) is a key compound that can be used to produce various chemical substances. In recent years, 2,3-BDO production ...

Biosynthesis of vanillin by different microorganisms: a review.
https://doi.org/10.1007/s11274-022-03228-1 10.1007/s13205-017-0998-9 10.1016/j.nbt.2011.06.009 10.1007/s12010-011-9397-6 10.3923/ijp.2011.144.148 10.1186/1475-2859-9-84 10.1371/journal.pone.0164955 10.1038/srep20400 10.1016/j.ymben.2020.07.006 10.1016/j.jbiotec.2011.08.014 10.1186/1754-6834-1-3 10.1128/AEM.00802-16 10.1016/S1389-1723(03)90146-0 10.1007/s00253-013-5303-1 10.1007/s00253-015-7197-6 10.1128/AEM.02681-08 10.1007/s00253-006-0735-5 10.3389/fmicb.2016.01059 10.1016/j.jbiotec.2017.04.024 10.1007/s00284-006-0627-z 10.1007/s12010-012-0066-1 10.1007/s00253-014-5950-x 10.1016/j.btre.2014.09.002 10.1021/acssynbio.9b00071 10.1021/ja506664a 10.1186/s12934-016-0459-x 10.1002/bit.22040 10.1021/ja9817747 10.1016/j.procbio.2008.06.006 10.1111/1751-7915.13643 10.1021/jf803366f 10.3389/fbioe.2019.00279 10.1007/s00449-013-1060-x 10.1007/s10295-013-1255-9 10.1016/j.jbiosc.2014.02.025 10.1038/srep13670 10.1128/AEM.69.11.6569-6576.2003 10.1128/mSystems.00163-19 10.1016/j.nbt.2017.07.012 10.1007/s00253-005-0302-5 10.1007/s002530100687 10.1002/1097-0010(200002)80:3<289::aid-jsfa543>3.0.co;2-2 10.1080/14786419.2020.1849194 10.1271/bbb.120375 10.1007/s10295-014-1515-3 10.1016/s0168-1656(99)00199-6 10.1021/jf904141u 10.1007/s00449-020-02482-7 10.1007/s11274-015-1876-4 10.1360/crad20050909 10.1186/s12896-016-0264-y 10.3389/fmicb.2017.00367 10.1007/s00253-006-0569-1 10.1007/s10529-007-9602-4 10.1007/s10529-005-3561-4 10.1021/bp070153r 10.1002/jsfa.5962
World Journal of Microbiology & Biotechnology; Ma Q, Liu L et. al.

Jan 13th, 2022 - Vanillin is a popular flavoring agent widely used around the world. Vanillin is generated by natural extraction, chemical synthesis, or tissue culture technology, but these production methods no longer meet the increasing worldwide demand for vanillin. Accordingly, a biotechnological approach may provide an effective replacement route to obtaining vanillin. Processes for environmentally friendl...

Functional properties of Rhizopus oryzae strains isolated from agricultural soils as a ...
https://doi.org/10.1007/s11274-021-03225-w 10.5539/jfr.v4n2p1 10.1080/1828051X.2016.1194173 10.1134/S0003683807050031 10.1111/lam.12300 10.1007/s00203-021-02251-4 10.3390/toxins10030104 10.1016/j.ijfoodmicro.2011.12.030 10.1186/1475-2891-7-29 10.1021/jf204163a 10.3389/fmicb.2019.02348 10.1016/j.ijgfs.2015.01.001 10.3389/fvets.2019.00516 10.1080/19476337.2017.1359676 10.1080/17450398909429530 10.1016/j.funbio.2015.12.001 10.3389/fmicb.2015.00350 10.5897/AJB09.620 10.1016/j.forsciint.2016.10.015 10.15744/2348-9790.1.603 10.1051/matecconf/201821501027 10.1079/WPS200584 10.1016/j.bmcl.2006.08.071 10.3390/nu9101101 10.1089/jmf.2004.7.430 10.1016/S0014-5793(00)01834-2 10.19080/nfsij.2018.04.555647 10.19087/jveteriner.2017.18.1.46 10.3390/ijms10083531 10.1186/s12941-015-0069-1 10.3390/fermentation5040099 10.2141/jpsa.0130022 10.5772/intechopen.72865 10.1371/journal.ppat.1002096 10.1016/j.tim.2009.09.003 10.1186/1471-2164-12-210 10.30574/wjarr 10.1007/s11274-008-9749-8 10.1016/S0168-1605(02)00563-9 10.1128/IAI.71.8.4250-4259.2003 10.1128/JCM.38.1.471-471.2000 10.1016/j.ijfoodmicro.2017.06.012 10.1177/1420326X04045274 10.1128/MMBR.64.3.461-488.2000 10.1186/2049-1891-6-4 10.1016/j.pbi.2009.06.004 10.7554/eLife.03007 10.3390/molecules14031032 10.1016/j.aninu.2019.05.005 10.1038/nature03997 10.1016/j.cub.2007.03.039 10.1111/j.1439-0507.2007.01477.x 10.1007/978-0-387-92207-2 10.3390/fermentation4030064 10.1016/j.ijfoodmicro.2009.10.010 10.1016/j.simyco.2014.07.004 10.1016/j.foodchem.2013.09.101 10.1038/ismej.2008.19 10.12777/ijse.4.2.97-102 10.1016/j.idairyj.2007.01.014 10.1038/srep06360 10.1146/annurev-animal-022513-114132 10.1590/fst.37218 10.1016/j.foodchem.2015.03.134 10.1016/j.jssas.2014.06.001 10.1016/j.aoas.2019.05.005 10.1016/j.aninu.2018.11.001 10.5941/MYCO.2015.43.4.415 10.3390/antiox5010006 10.3382/japr/pfy027 10.3389/fevo.2019.00118 10.1007/s00449-013-0924-4
World Journal of Microbiology & Biotechnology; Hamza AA, Gunyar OA

Jan 13th, 2022 - The most crucial and expensive fragment in the broiler chicken production industry is the feed. Because of the rising demand, finding a cheap and effective feed is an urgent necessity. Fermentation of broiler feed by probiotic fungal starters can enhance the nutrient's availability and digestibility while preventing pathogenic growth. In this study different Rhizopus spp. have been isolated fro...

Removal of antibiotic thiamphenicol by bacterium Aeromonas hydrophila HS01.
https://doi.org/10.1007/s11274-021-03223-y 10.21769/BioProtoc.2003595
World Journal of Microbiology & Biotechnology; Yang K, Ren S et. al.

Jan 13th, 2022 - Thiamphenicol (TAP) is an amphenicol antibiotic, which has a broad-spectrum inhibitory effect on both gram-positive and gram-negative bacteria. Since it is widely used in animals and aquaculture, its residues in environment may bring potential risk for human health and ecosystems. While TAP can be removed through conventional physical or chemical methods, its bioremediation using microorganisms...

The combination of sucrose dilaurate and sucrose laurate suppresses HMGB1: an enhancer ...
https://doi.org/10.1111/jdv.17846
Journal of the European Academy of Dermatology and Venere... Wang J, Jarrold B et. al.

Jan 12th, 2022 - Hyperpigmented spots are common issues in all ethnicities, involving multiple intrinsic and extrinsic factors such as UVB exposure, hormone balance, inflammatory status and ageing. To determine (i) melanocyte dendricity in multiple facial spot types, (ii) impact of High Mobility Group Box 1 (HMGB1), and the combination of sucrose dilaurate and sucrose laurate (SDL) on melanogenesis and melanocy...

10Z‑Hymenialdisine inhibits angiogenesis by suppressing NF‑κB activation in pancreatic ...
https://doi.org/10.3892/or.2022.8259
Oncology Reports; Ueda G, Matsuo Y et. al.

Jan 12th, 2022 - 10Z‑Hymenialdisine is a natural product derived from the marine sponge Axinella carteri. 10Z‑Hymenialdisine has anti‑inflammatory effects exerted through NF‑κB; however, it is unclear whether 10Z‑Hymenialdisine has anti‑angiogenic effects in cancer cells. In the present study, both the anti‑angiogenic and antimetastatic effects of this compound in pancreatic cancer were investigated. It was ini...

Neuroprotective Efficiency of Prodigiosins Conjugated with Selenium Nanoparticles in Ra...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722537
International Journal of Nanomedicine; Albrakati A, Alsharif KF et. al.

Jan 11th, 2022 - Depression is a mood disorder accompanied by intensive molecular and neurochemical alterations. Currently, available antidepressant therapies are not fully effective and are often accompanied by several adverse impacts. Accordingly, the ultimate goal of this investigation was to clarify the possible antidepressant effects of prodigiosins (PDGs) loaded with selenium nanoparticles (PDGs-SeNPs) in...

Genome-wide identification and expression analysis of the coronatine-insensitive 1 (COI...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742417
BMC Genomics; Sun T, Meng Y et. al.

Jan 10th, 2022 - The coronatine insensitive 1 (COI1) gene is the core member of jasmonate signaling pathway, which is closely related to plant biotic and abiotic resistance. However, there have been no reports on COI1 in sugarcane (Sacharum spp.). Hence, systematically investigating the characteristics of the COI1 multigene family in sugarcane can provide a means to study and manipulate the jasmonic acid signal...

Glucose levels during gestational diabetes pregnancy and the risk of developing postpar...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742366
BMC Pregnancy and Childbirth; Phaloprakarn C, Tangjitgamol S

Jan 9th, 2022 - Blood glucose levels during pregnancy may reflect the severity of insulin secretory defects and/or insulin resistance during gestational diabetes mellitus (GDM) pregnancy. We hypothesized that suboptimal glycemic control in women with GDM could increase the risk of postpartum type 2 diabetes mellitus (T2DM) or prediabetes. Our objective was to evaluate the impact of plasma glucose levels throug...

Predicting the targets of IRF8 and NFATc1 during osteoclast differentiation using the m...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740472
BMC Genomics; Wang H, Joshi P et. al.

Jan 8th, 2022 - Interferon regulatory factor-8 (IRF8) and nuclear factor-activated T cells c1 (NFATc1) are two transcription factors that have an important role in osteoclast differentiation. Thanks to ChIP-seq technology, scientists can now estimate potential genome-wide target genes of IRF8 and NFATc1. However, finding target genes that are consistently up-regulated or down-regulated across different studies...