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About 358,823 results

Epidemiology and bacterial characteristics of invasive group B streptococcus disease: a...
https://doi.org/10.1017/S0950268822001534
Epidemiology and Infection; Takeuchi N, Chang B et. al.

Nov 22nd, 2022 - This is the first report on a population-based prospective study of invasive group B streptococcus (GBS) disease among children aged <15 years conducted over a period of 11 years in Japan. This study investigated the incidence and clinical manifestations of invasive GBS disease in children in Chiba Prefecture, Japan, and analysed the serotypes and drug susceptibility of GBS strains isolated dur...

Immunoinformatics analysis of candidate proteins for controlling bovine paratuberculosis.
https://doi.org/10.1371/journal.pone.0277751
PloS One; Moezzi MS, Derakhshandeh A et. al.

Nov 22nd, 2022 - Paratuberculosis is debilitating chronic enteritis usually characterized by diarrhea, decreased milk production, and progressive cachexia. Mycobacterium avium subspecies paratuberculosis (MAP) causes significant economic losses by affecting dairy herds globally. Development of protective vaccines is considered as one of the most effective controlling measures for MAP infections. In the current ...

Taxonomic and functional profiling of Indian smokeless tobacco bacteriome uncovers seve...
https://doi.org/10.1007/s11274-022-03461-8
World Journal of Microbiology & Biotechnology; Vishwakarma A, Srivastava A et. al.

Nov 22nd, 2022 - Smokeless tobacco (ST) consumption keeps human oral health at high risk which is one of the major reasons for oral tumorigenesis. The chemical constituents of the ST products have been well discussed; however, the inhabitant microbial diversity of the ST products is less explored especially from south Asian regions. Therefore, the present investigation discusses the bacteriome-based analysis of...

Investigating nanomotion-based technology (Resistell AST) for rapid antibiotic suscepti...
https://doi.org/10.1136/bmjopen-2022-064016
BMJ Open; Caruana G, Kritikos A et. al.

Nov 22nd, 2022 - Effective treatment of bloodstream infections (BSIs) is relying on rapid identification of the causing pathogen and its antibiotic susceptibility. Still, most commercially available antibiotic susceptibility testing (AST) methods are based on monitoring bacterial growth, thus impacting the time to results. The Resistell AST is based on a new technology measuring the nanomotion caused by physiol...

Long-range dependence and extreme values of precipitation, phosphorus load, and Cyanoba...
https://doi.org/10.1073/pnas.2214343119
Proceedings of the National Academy of Sciences of the Un... Carpenter SR, Gahler MR et. al.

Nov 22nd, 2022 - Extreme daily values of precipitation (1939-2021), discharge (1991-2021), phosphorus (P) load (1994-2021), and phycocyanin, a pigment of Cyanobacteria (June 1-September 15 of 2008-2021) are clustered as multi-day events for Lake Mendota, Wisconsin. Long-range dependence, or memory, is the shortest for precipitation and the longest for phycocyanin. Extremes are clustered for all variates and tho...

Central Nervous System Mycobacterium Infection: Tuberculosis and Beyond.
https://doi.org/10.1016/j.nic.2022.07.006
Neuroimaging Clinics of North America; Park M, Gupta RK

Nov 21st, 2022 - Tuberculosis is a contagious infectious disease caused by Mycobacterium tuberculosis, and is the leading cause of death from a single infectious agent worldwide. Imaging plays an important role in the early diagnosis of central nervous system tuberculosis and may prevent unnecessary morbidity and mortality. This article presents an extensive review of pathogenesis, clinical symptoms, typical an...

Initial empirical antibiotics of non-carbapenems for ESBL-producing E. coli and K. pneu...
https://doi.org/10.1186/s12879-022-07881-7
BMC Infectious Diseases; Park S, So H et. al.

Nov 21st, 2022 - The efficacy of non-carbapenems as an empirical antibiotic for extended-spectrum β-lactamases (ESBL)-producing Escherichia coli and Klebsiella pneumoniae bacteremia in children remains controversial. We compared clinical and microbial outcomes according to the types of empirical antibiotics for treating pediatric patients with ESBL-producing E. coli and K. pneumoniae bacteremia. Data from pedia...

Analysis of sputum microbial metagenome in COPD based on exacerbation frequency and lun...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675190
Respiratory Research; Li W, Wang B et. al.

Nov 20th, 2022 - The role of the sputum microbiome in chronic obstructive pulmonary disease (COPD) progression remains elusive. As the advent of the new culture-independent microbial sequencing technique makes it possible to disclose the complex microbiome community of the respiratory tract. The aim of this study was to use metagenomic next-generation sequencing (mNGS) to confirm whether there are differences i...

Triclosan exposure induced disturbance of gut microbiota and exaggerated experimental c...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675201
BMC Gastroenterology; Liu J, Tao Y et. al.

Nov 20th, 2022 - Triclosan, an antimicrobial agent in personal care products, could be absorbed into the human body through the digestive tract. This animal experiment aimed to clarify the effects of triclosan exposure on the microbiome and intestinal immune functions in healthy and ulcerative colitis models. Balb/c mice were maintained on an AIN-93G diet containing 80ppm triclosan dissolved in polyethylene as ...

The systemic oral health connection: Biofilms.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678577
Medicine Kurtzman GM, Horowitz RA et. al.

Nov 20th, 2022 - Frequently, periodontal health and it's associated oral biofilm has not been addressed in those patients who have systemic health issues, especially those who are not responding to medical treatment via their physician. Oral biofilm may be present in the periodontal sulcus in the absence of clinical disease of periodontal disease (bleeding on probing, gingival inflammation) and periodontal reac...

Value of sputum Gram stain, sputum culture, and bronchoalveolar lavage fluid Gram stain...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675245
BMC Pulmonary Medicine; Zhang R, Wu Y et. al.

Nov 20th, 2022 - Currently, the microbial etiology of community-acquired pneumonia in children remains challenging. While Gram stain and sputum culture are commonly used to detect bacterial pathogens, it is unclear whether these approaches can predict single pathogen from bronchoalveolar lavage fluid (BALF) culture. A retrospective study involving 287 children hospitalized for pneumonia was conducted. Sputum sp...

Mycoplasma hominis and Ureaplasma urealyticum infections after knee arthroplasty: A cas...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666090
Medicine Luo J, Wu X et. al.

Nov 19th, 2022 - Artificial joint infection caused by Mycoplasma hominis and Ureaplasma urealyticum is rare and has not been reported. A 59-year-old man underwent left total knee arthroplasty for 1 year of pain in the left knee joint. The indwelling urinary catheter was removed after 48 hour of the surgery. On day 8 after the surgery, the patient had fever, increased skin temperature, swelling and redness aroun...

Cost-effectiveness of single, high-dose, liposomal amphotericin regimen for HIV-associa...
https://doi.org/10.1016/S2214-109X(22)00450-8
The Lancet. Global Health; Lawrence DS, Muthoga C et. al.

Nov 19th, 2022 - HIV-associated cryptococcal meningitis is a leading cause of AIDS-related mortality. The AMBITION-cm trial showed that a regimen based on a single high dose of liposomal amphotericin B deoxycholate (AmBisome group) was non-inferior to the WHO-recommended treatment of seven daily doses of amphotericin B deoxycholate (control group) and was associated with fewer adverse events. We present a five-...

Aerococcus urinae, a rare cause of aortic root abscess: a case report.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670598
Journal of Medical Case Reports; Tiong CW, Bartolo C et. al.

Nov 19th, 2022 - Aerococcus urinae is a bacterium of emerging clinical interest that most commonly causes urinary tract infections (UTI) but can also result in invasive infections. It is a catalase-negative, alpha-haemolytic gram-positive coccus that grows in clusters or tetrads and usually causes urinary tract infections. While rare, infective endocarditis must be considered when A. urinae is isolated in blood...

Modulation of the porcine intestinal microbiota in the course of Ascaris suum infection.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673396
Parasites & Vectors; Springer A, Wagner L et. al.

Nov 19th, 2022 - The porcine roundworm Ascaris suum impairs feed conversion and weight gain, but its effects on intestinal microbiota remain largely unexplored. Modulation of the intestinal microbiota was assessed in pigs that were infected once with 10,000 A. suum eggs and pigs that received a trickle infection (1000 eggs/day over 10 days), compared with a non-infected control group. Six pigs each were sacrifi...

Impact of Steroids as Adjuvant Therapy in Acute Bacterial Infections of Childhood.
https://doi.org/10.1542/peds.2021-053062
Pediatrics Wald ER, Eickhoff JC

Nov 19th, 2022 - Impact of Steroids as Adjuvant Therapy in Acute Bacterial Infections of Childhood.|2022|Wald ER,Eickhoff JC,|drug therapy,microbiology,

Evaluation of ERIC-PCR and MALDI-TOF as typing tools for multidrug resistant Klebsiella...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671336
PloS One; Kundu J, Kansal S et. al.

Nov 18th, 2022 - Multidrug resistant Klebsiella pneumoniae is associated with nosocomial infections in both outbreak and non-outbreak situations. The study intends to evaluate the potential of enterobacterial repetitive intergenic consensus- polymerase chain reaction (ERIC-PCR), a genomic based typing and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) proteomic-based...

1H NMR metabolic profiling of Staphylococcus pseudintermedius isolated from canine urol...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671361
PloS One; Uttamamul N, Suksawat M et. al.

Nov 18th, 2022 - Staphylococcus pseudintermedius is a urease-producing bacteria which is a major cause of magnesium ammonium phosphate (MAP) urolithiasis in canine. A positive urolith culture is an important risk factor for MAP urolithiasis in canine. The mechanism underlying the metabolic changes of S. pseudintermedius after crystallization in artificial urine (AU) needs more defined baseline metabolic informa...

Efficacy of surgical skin preparation solutions in hip arthroplasty: a prospective rand...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671291
Canadian Journal of Surgery. Journal Canadien De Chirurgie; Droll KP, Abouassaly M et. al.

Nov 18th, 2022 - The use of an effective antimicrobial preoperative skin preparation solution is essential in preventing infections after surgery, but the findings in the literature regarding efficacy are not necessarily applicable to surgery involving the hip. The purpose of the present study was twofold: 1) to examine the native bacteria on the skin at the hip and 2) to determine the efficacy of 2 surgical sk...

Novel care pathway to optimise antimicrobial prescribing for uncomplicated community-ac...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9677018
BMJ Open; Pernica JM, Kam AJ et. al.

Nov 18th, 2022 - Evidence-based recommendations for paediatric community-acquired pneumonia (CAP) diagnosis and management are needed. Uncomplicated CAP is often caused by respiratory viruses, especially in younger children; these episodes self-resolve without antibiotic treatment. Unfortunately, there are no clinical criteria that reliably discriminate between viral and bacterial disease, and so the majority o...