×
About 536,550 results

Machine-learning-based COVID-19 mortality prediction model and identification of patien...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424411
Critical Care (London, England); Banoei MM, Dinparastisaleh R et. al.

Sep 10th, 2021 - The coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-Cov2 virus has become the greatest health and controversial issue for worldwide nations. It is associated with different clinical manifestations and a high mortality rate. Predicting mortality and identifying outcome predictors are crucial for COVID patients who are critically ill. Multivariate and machine learning methods may ...

Bridging antifungal prophylaxis with micafungin in hematopoietic stem cell transplantat...
https://doi.org/10.1080/16078454.2021.1959982
Hematology (Amsterdam, Netherlands); Zhang H

Sep 9th, 2021 - The objective of the study was to assess the tolerability and effectiveness of micafungin prophylaxis during the neutropenic phase in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Methods We conducted a retrospective study of 73 consecutive adults receiving antifungal prophylaxis with micafungin bridged to voriconazole/itraconazole in our center from July 2013 t...

Latent Epstein-Barr virus infection status and prognosis in patients with newly diagnos...
https://doi.org/10.1080/16078454.2021.1971864
Hematology (Amsterdam, Netherlands); Wang C, Zou SP et. al.

Sep 9th, 2021 - This study aimed to investigate the latent Epstein-Barr virus (EBV) infection status of patients with newly diagnosed Hodgkin lymphoma (HL) and to discuss the relationship between tumor cell EBV status and the prognosis of HL patients. A total of 134 previously untreated HL patients were analyzed in the study. Epstein-Barr virus encoded RNAs (EBERs) in situ hybridization was performed to detect...

Impact of long-term exposure to PM2.5 and temperature on coronavirus disease mortality:...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420152
Environmental Health : a Global Access Science Source; Tchicaya A, Lorentz N et. al.

Sep 8th, 2021 - The outbreak of coronavirus disease (COVID-19) began in Wuhan, China in December 2019 and was declared a global pandemic on 11 March 2020. This study aimed to assess the effects of temperature and long-term exposure to air pollution on the COVID-19 mortality rate at the sub-national level in France. This cross-sectional study considered different periods of the COVID-19 pandemic from May to Dec...

The association between physical activity, sedentary time and health-related quality of...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419900
Health and Quality of Life Outcomes; Yan R, Che B et. al.

Sep 8th, 2021 - Although physical activity (PA) and sedentary time in cancer survivors (CSs) were associated with health-related quality of life (HRQOL), it was not clear whether their associations were similar among CSs with different number of comorbid chronic diseases (CCDs). This study aimed to investigate the associations between PA, sedentary time and HRQOL in CSs with different number of CCDs. A cross-s...

Efficacy and safety of direct-acting oral anticoagulants compared to vitamin K antagoni...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417638
Cardiovascular Diabetology; Rivera-Caravaca JM, Harrison SL et. al.

Sep 6th, 2021 - It remains uncertain if prior use of oral anticoagulants (OACs) in COVID-19 outpatients with multimorbidity impacts prognosis, especially if cardiometabolic diseases are present. Clinical outcomes 30-days after COVID-19 diagnosis were compared between outpatients with cardiometabolic disease receiving vitamin K antagonist (VKA) or direct-acting OAC (DOAC) therapy at time of COVID-19 diagnosis. ...

Could Clinician Sensitivity to Cultural and Historical Considerations Help Reduce COVID...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395970
Southern Medical Journal; Kountz D, Rodriguez F et. al.

Sep 5th, 2021 - Could Clinician Sensitivity to Cultural and Historical Considerations Help Reduce COVID-19 Deaths among Blacks?|2021|Kountz D,Rodriguez F,Vital V,Vora S,Gough R,|statistics & numerical data,ethnology,mortality,methods,statistics & numerical data,ethnology,epidemiology,

Analysis of the Effects of COVID-19 Mask Mandates on Hospital Resource Consumption and ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395971
Southern Medical Journal; Schauer SG, Naylor JF et. al.

Sep 5th, 2021 - Coronavirus disease 2019 (COVID-19) threatens vulnerable patient populations, resulting in immense pressures at the local, regional, national, and international levels to contain the virus. Laboratory-based studies demonstrate that masks may offer benefit in reducing the spread of droplet-based illnesses, but few data are available to assess mask effects via executive order on a population basi...

BAI1 as a Prognostic Marker of Clear Cell Renal Cell Carcinoma (ccRCC).
https://doi.org/10.21873/anticanres.15255
Anticancer Research; Pesta M, Travnicek I et. al.

Sep 4th, 2021 - The treatment of advanced clear cell renal cell carcinoma (ccRCC) is based on stratification of patients according to prognosis (favorable, intermediate, and poor). The aim of the study was to improve prognostication by biomarkers involved in angiogenesis. The study group consisted of 20 patients who underwent surgery for ccRCC. Gene expression analysis was peformed on a set of matched (primary...

Prognostic Value of CD45Ro+ T-Cell Expression in Patients With Oral Squamous Cell Carci...
https://doi.org/10.21873/anticanres.15262
Anticancer Research; Koike K, Nishiyama K et. al.

Sep 4th, 2021 - The role of tumour-infiltrating CD45Ro+ T-cells in oral squamous cell carcinoma (OSCC) is unclear. This study aimed to evaluate prognostic biomarkers for OSCC. We determined the density of tumour-infiltrating CD45Ro+ T cells in the parenchyma and stroma at the tumour centre (TCe) and invasive front (IF) and examined the association between the density of these cells and histopathological status...

The Real-world Outcomes of Patients With Advanced Invasive Lobular Carcinoma of the Bre...
https://doi.org/10.21873/anticanres.15275
Anticancer Research; Watanabe J, Nakamoto S et. al.

Sep 4th, 2021 - The real-world outcomes of patients with advanced invasive lobular carcinoma (ILC) of the breast are unclear because of its rarity. We identified 435 patients with estrogen receptor-positive (ER+), HER2-negative (HER2-) advanced breast cancer treated at our Institute between 2002 and 2019, and analyzed their outcomes retrospectively. We identified 29 patients with advanced ILC. At presentation,...

Efficacy and safety of PD-1/PD-L1 inhibitors combined with CTLA-4 inhibitor versus chem...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416009
Medicine Zhang PP, Wang J et. al.

Sep 4th, 2021 - This meta-analysis was performed to compare efficacy and tolerability between antiprogrammed cell death (PD-1)/programmed cell death-ligand-1 (PD-L1) + anticytotoxic T-lymphocyte-associated protein-4 (CTLA-4) treatment and chemotherapy in advanced lung cancer. Cochrane Library, Embase, and PubMed databases were searched for potential articles. The fixed-effect model or random-effect model was a...

Multiple genetic variants predict the progression-free survival of bevacizumab plus che...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415939
Medicine Gao J, Li F et. al.

Sep 4th, 2021 - Bevacizumab (BV) plus chemotherapy is broadly used in advanced ovarian cancer (OC). However, the efficacy of BV-based regimens for advanced OC patients is not satisfactory. Therefore, it is urgent to explore the predictive genetic biomarkers for BV.Tumor tissues from advanced OC patients receiving BV-based regimens were analyzed with a 150-gene targeted panel for next generation sequencing. The...

Mesonephric adenocarcinomas in female genital tract: A case series.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416001
Medicine Xie C, Chen Q et. al.

Sep 4th, 2021 - Mesonephric adenocarcinoma (MNAC) is a very rare tumor that originates from mesonephric duct remnants of the female genital tract. Only a few cases were reported in the literature, and most of them occurred in the cervix, extremely rare in the uterine body and ovary. MNAC was rarely reported to arise in the uterine corpus, but never was reported in the ovary. Mesonephric-like adenocarcinomas ar...

Optimal extent of lymphadenectomy for radical surgery of pancreatic head adenocarcinoma...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415937
Medicine Wang Z, Ke N et. al.

Sep 4th, 2021 - Radical pancreaticoduodenectomy is the only possible cure for pancreatic head adenocarcinoma, and although several RCT studies have suggested the extent of lymph node dissection, this issue remains controversial. This article wanted to evaluate the survival benefit of different lymph node dissection extent for radical surgical treatment of pancreatic head adenocarcinoma. A total of 240 patients...

Prognostic significance of long non coding maternally expressed gene 3 in pediatric acu...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415930
Medicine Xue H, Gao H et. al.

Sep 4th, 2021 - The purpose of this study was to evaluate the correlation of long non-coding RNA maternally expressed gene 3 (Lnc-MEG3) with disease features, treatment response, and survival in pediatric acute myeloid leukemia (AML) patients.Among 92 de novo pediatric AML patients (before treatment and after 1 course of induction) and 40 controls, bone marrow mononuclear cells were obtained. Then, Lnc-MEG3 ex...

Short- and long-term prognosis of acute critically ill patients with systemic rheumatic...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415942
Medicine Chabert P, Danjou W et. al.

Sep 4th, 2021 - Patients with systemic rheumatic disease (SRD) share the risks of multi-organ flare-up, cardiovascular diseases, and immunosuppression. Such situations can lead to an acute critical illness. The present study describes the clinical features of SRD patients admitted to the intensive care unit (ICU) and their short- and long- term mortality.We performed a multicentre retrospective study in 10 Fre...

Characteristics and mortality in primary Sjögren syndrome-related interstitial lung dis...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415932
Medicine Gao H, Sun Y et. al.

Sep 4th, 2021 - Aim of the study was to determine the characteristics and prognosis, and to identify the risk factors for mortality in patients with primary Sjögren syndrome (pSS) with interstitial lung disease (pSS-ILD).A total of 1422 patients with SS were screened and 178 patients with pSS-ILD were recruited. The medical records and outcomes were retrospectively reviewed. Overall survival and case control s...

3-weekly daratumumab-lenalidomide/pomalidomide-dexamethasone is highly effective in rel...
https://doi.org/10.1080/16078454.2021.1965737
Hematology (Amsterdam, Netherlands); Chim CS, Kumar S et. al.

Sep 4th, 2021 - Myeloma relapse remains challenging. Daratumumab (dara) with immunomodulatory agents (IMiD) and dexamethasone (dex) was proven highly effective in relapsed or refractory multiple myeloma (RRMM) in randomized controlled trials. The recommended schedule of dara is weekly for eight doses, followed by 2-weekly for eight doses, and then every 4-weekly thereafter. However, the cost of daratumumab is ...

Long term exposure to low level air pollution and mortality in eight European cohorts w...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8409282
BMJ (Clinical Research Ed.); Strak M, Weinmayr G et. al.

Sep 3rd, 2021 - To investigate the associations between air pollution and mortality, focusing on associations below current European Union, United States, and World Health Organization standards and guidelines. Pooled analysis of eight cohorts. Multicentre project Effects of Low-Level Air Pollution: A Study in Europe (ELAPSE) in six European countries. 325 367 adults from the general population recruited mostl...