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About 563,610 results

Consumption of coffee and tea with all-cause and cause-specific mortality: a prospectiv...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673438
BMC Medicine; Chen Y, Zhang Y et. al.

Nov 19th, 2022 - Previous studies suggested that moderate coffee and tea consumption are associated with lower risk of mortality. However, the association between the combination of coffee and tea consumption with the risk of mortality remains unclear. This study aimed to evaluate the separate and combined associations of coffee and tea consumption with all-cause and cause-specific mortality. This prospective c...

Is the prognosis of non-hypertensive, COVID-19 patients treated with renin-angiotensin-...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672383
Physiological Reports; García Martínez JJ, Wozniak H et. al.

Nov 19th, 2022 - Previous studies suggested that ongoing treatment with renin-angiotensin-aldosterone system (RAAS) inhibitor drugs may alter the course of SARS-CoV-2 infection and promote the development of more severe forms of the disease. The authors conducted a comparative, observational study to retrospectively analyze data collected from 394 patients admitted to ICU due to SARS-CoV-2 pneumonia. The primar...

Paradoxes of breast cancer incidence and mortality in two corners of Europe.
https://doi.org/10.1186/s12885-022-10243-w
BMC Cancer; Roginski M, Sifaki-Pistolla D et. al.

Nov 3rd, 2022 - Breast cancer incidence is rising globally, while mortality rates show a geographical heterogenous pattern. Early detection and treatment have been proven to have a profound impact on breast cancer prognosis. The aim of his study was to compare breast cancer incidence, mortality, and survival rates in two contrasting corners of Europe, Sweden and Crete, to better understand cancer determinants ...

Prognostic factors for mortality, intensive care unit and hospital admission due to SAR...
https://doi.org/10.1183/16000617.0098-2022
European Respiratory Review : an Official Journal of the ... Vardavas CI, Mathioudakis AG et. al.

Nov 3rd, 2022 - As mortality from coronavirus disease 2019 (COVID-19) is strongly age-dependent, we aimed to identify population subgroups at an elevated risk for adverse outcomes from COVID-19 using age-/gender-adjusted data from European cohort studies with the aim to identify populations that could potentially benefit from booster vaccinations. We performed a systematic literature review and meta-analysis t...

Effect of asthma, COPD, and ACO on COVID-19: A systematic review and meta-analysis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624422
PloS One; Uruma Y, Manabe T et. al.

Nov 2nd, 2022 - The prevalence of asthma, chronic obstructive pulmonary disease (COPD), and asthma-COPD overlap (ACO) in patients with COVID-19 varies, as well as their risks of mortality. The present study aimed to assess the prevalence of asthma, COPD, and ACO as comorbidities, and to determine their risks of mortality in patients with COVID-19 using a systematic review and meta-analysis. We systematically r...

Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Pers...
https://doi.org/10.1001/jama.2022.18324
JAMA Gartlehner G, Patel SV et. al.

Nov 2nd, 2022 - It is uncertain whether hormone therapy should be used for the primary prevention of chronic conditions such as heart disease, osteoporosis, or some types of cancers. To update evidence for the US Preventive Services Task Force on the benefits and harms of hormone therapy in reducing risks for chronic conditions. PubMed/MEDLINE, Cochrane Library, EMBASE, and trial registries from January 1, 201...

Extreme escalation of heat failure rates in ectotherms with global warming.
https://doi.org/10.1038/s41586-022-05334-4
Nature Jørgensen LB, Ørsted M et. al.

Oct 27th, 2022 - Temperature affects the rate of all biochemical processes in ectotherms1,2 and is therefore critical for determining their current and future distribution under global climate change3-5. Here we show that the rate of biological processes maintaining growth, homeostasis and ageing in the permissive temperature range increases by 7% per degree Celsius (median activation energy Ea = 0.48 eV from 1...

Effect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge A...
https://doi.org/10.1001/jama.2022.17701
JAMA Bernard SA, Bray JE et. al.

Oct 27th, 2022 - The administration of a high fraction of oxygen following return of spontaneous circulation in out-of-hospital cardiac arrest may increase reperfusion brain injury. To determine whether targeting a lower oxygen saturation in the early phase of postresuscitation care for out-of-hospital cardiac arrest improves survival at hospital discharge. This multicenter, parallel-group, randomized clinical ...

Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With Mild ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587497
JAMA Naggie S, Boulware DR et. al.

Oct 22nd, 2022 - The effectiveness of ivermectin to shorten symptom duration or prevent hospitalization among outpatients in the US with mild to moderate symptomatic COVID-19 is unknown. To evaluate the efficacy of ivermectin, 400 μg/kg, daily for 3 days compared with placebo for the treatment of early mild to moderate COVID-19. ACTIV-6, an ongoing, decentralized, double-blind, randomized, placebo-controlled pl...

A hybrid of long short-term memory neural network and autoregressive integrated moving ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580197
BMC Public Health; Chen Y, He J et. al.

Oct 20th, 2022 - To forecast the human immunodeficiency virus (HIV) incidence and mortality of post-neonatal population in East Asia including North Korea, South Korea, Mongolia, Japan and China Mainland and Taiwan province. The data on the incidence and mortality of HIV in post-neonatal population from East Asia were obtained from the Global Burden of Diseases (GBD). The morbidity and mortality of post-neonata...

Observational study of factors associated with morbidity and mortality from COVID-19 in...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581355
PloS One; Nader M, Zmerli O et. al.

Oct 20th, 2022 - The COVID-19 pandemic claimed millions of lives worldwide without clear signs of abating despite several mitigation efforts and vaccination campaigns. There have been tremendous interests in understanding the etiology of the disease particularly in what makes it severe and fatal in certain patients. Studies have shown that COVID-19 patients with kidney injury on admission were more likely to de...

Accuracy of SCORTEN in predicting mortality in toxic epidermal necrolysis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583545
BMC Medical Informatics and Decision Making; Strużyna J, Surowiecka A et. al.

Oct 20th, 2022 - Toxic epidermal necrolysis (TEN) patients require multi-directional and multi-disciplinary treatment. In most cases, they are hospitalised at intensive care units and require multi-directional, burn-complication preventive care. Choosing the most appropriate treatment option might be troublesome even when predicting scores are used. SCORTEN is the most renowned prognostic score for TEN patients...

Evolution of immune genes is associated with the Black Death.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580435
Nature Klunk J, Vilgalys TP et. al.

Oct 20th, 2022 - Infectious diseases are among the strongest selective pressures driving human evolution1,2. This includes the single greatest mortality event in recorded history, the first outbreak of the second pandemic of plague, commonly called the Black Death, which was caused by the bacterium Yersinia pestis3. This pandemic devastated Afro-Eurasia, killing up to 30-50% of the populat...

Preoperative fibrinogen level and postcardiac surgery morbidity and mortality rates.
https://doi.org/10.4103/aca.aca_103_21
Annals of Cardiac Anaesthesia; Fricault P, Piot J et. al.

Oct 19th, 2022 - High preoperative fibrinogen levels are associated with reduced bleeding rates after cardiac surgery. Fibrinogen is directly involved in inflammatory processes and is a cardiovascular risk factors. Whether high fibrinogen levels before cardiac surgery are a risk factor for mortality or morbidity remains unclear. This study aimed to examine the association between preoperative fibrinogen levels ...

Estimate: 10.5 Million Children Lost a Parent, Caregiver to COVID-19.
https://doi.org/10.1001/jama.2022.15475
JAMA Bellandi D

Oct 19th, 2022 - Estimate: 10.5 Million Children Lost a Parent, Caregiver to COVID-19.|2022|Bellandi D,|statistics & numerical data,epidemiology,mortality,statistics & numerical data,

Cross-sectional study for COVID-19-related mortality predictors in a Brazilian state-wi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9577275
BMJ Open; Gustani-Buss EG, Buss CE et. al.

Oct 18th, 2022 - The Brazilian state of Paraná has suffered from COVID-19 effects, understanding predictors of increased mortality in health system interventions prevent hospitalisation of patients. We selected the best models to evaluate the association of death with demographic characteristics, symptoms and comorbidities based on three levels of clinical severity for COVID-19: non-hospitalised, hospitalised n...

Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion.
https://doi.org/10.1056/NEJMoa2207576
The New England Journal of Medicine; Jovin TG, Li C et. al.

Oct 15th, 2022 - The effects and risks of endovascular thrombectomy 6 to 24 hours after stroke onset due to basilar-artery occlusion have not been extensively studied. In a trial conducted over a 5-year period in China, we randomly assigned, in a 1:1 ratio, patients with basilar-artery stroke who presented between 6 to 24 hours after symptom onset to receive either medical therapy plus thrombectomy or medical t...

Trial of Endovascular Treatment of Acute Basilar-Artery Occlusion.
https://doi.org/10.1056/NEJMoa2206317
The New England Journal of Medicine; Tao C, Nogueira RG et. al.

Oct 15th, 2022 - Data from trials investigating the effects and risks of endovascular thrombectomy for the treatment of stroke due to basilar-artery occlusion are limited. We conducted a multicenter, prospective, randomized, controlled trial of endovascular thrombectomy for basilar-artery occlusion at 36 centers in China. Patients were assigned, in a 2:1 ratio, within 12 hours after the estimated time of basila...

Lowest US Life Expectancy Since 1996 Linked to COVID-19.
https://doi.org/10.1001/jama.2022.15455
JAMA Kuehn BM

Oct 12th, 2022 - Lowest US Life Expectancy Since 1996 Linked to COVID-19.|2022|Kuehn BM,|mortality,trends,epidemiology,

Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death.
https://doi.org/10.1056/NEJMoa2208375
The New England Journal of Medicine; Bretthauer M, Løberg M et. al.

Oct 11th, 2022 - Although colonoscopy is widely used as a screening test to detect colorectal cancer, its effect on the risks of colorectal cancer and related death is unclear. We performed a pragmatic, randomized trial involving presumptively healthy men and women 55 to 64 years of age drawn from population registries in Poland, Norway, Sweden, and the Netherlands between 2009 and 2014. The participants were r...