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About 96,148 results

COVID-19 and malaria, a tale of two diseases.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382951
EBioMedicine EBioMedicine

Aug 29th, 2021 - COVID-19 and malaria, a tale of two diseases.|2021|EBioMedicine ,|analysis,diagnosis,virology,analysis,genetics,diagnosis,parasitology,isolation & purification,metabolism,analysis,isolation & purification,metabolism,

Recreational behaviour, risk perceptions, and protective practices against ticks: a cro...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381130
Parasites & Vectors; Borșan SD, Trif SR et. al.

Aug 25th, 2021 - Gaining insight into the risk perceptions and the knowledge evolution of the public about emerging or changing health risks is vital for the improvement of health promotion activities. Currently, scientific evidence regarding the attitudes of the Romanian public towards ticks is scanty. This study aimed to identify how the lockdown enforced by the COVID-19 pandemic in Romania impacted the recre...

Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357946
Nature Communications; Ofir-Birin Y, Ben Ami Pilo H et. al.

Aug 13th, 2021 - Pathogens are thought to use host molecular cues to control when to initiate life-cycle transitions, but these signals are mostly unknown, particularly for the parasitic disease malaria caused by Plasmodium falciparum. The chemokine CXCL10 is present at high levels in fatal cases of cerebral malaria patients, but is reduced in patients who survive and do not have complications. Here we show a P...

CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasm...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355313
Nature Communications; Boltryk SD, Passecker A et. al.

Aug 12th, 2021 - The malaria parasite Plasmodium falciparum replicates inside erythrocytes in the blood of infected humans. During each replication cycle, a small proportion of parasites commits to sexual development and differentiates into gametocytes, which are essential for parasite transmission via the mosquito vector. Detailed molecular investigation of gametocyte biology and transmission has been hampered...

A new dicistro-like virus from soldier fly, Inopus flavus (Diptera: Stratiomyidae), a p...
https://doi.org/10.1007/s00705-021-05171-2 10.1071/ZO9880627 10.1603/0022-0493-94.5.1097 10.1111/1744-7917.12676 10.1099/0022-1317-69-7-1617 10.1099/jgv.0.000756 10.1186/1743-422X-6-193 10.1093/nar/gky1121 10.1099/vir.0.79992-0 10.1159/000149886 10.1159/000149489 10.1099/0022-1317-69-4-787 10.1016/0042-6822(81)90275-0 10.1006/jipa.1997.4721 10.1099/0022-1317-73-4-1021 10.1016/j.virol.2004.07.016 10.1111/j.1744-7348.1985.tb03136.x 10.1099/vir.0.83284-0 10.1099/vir.0.000068 10.1111/j.1570-7458.2008.00675.x 10.1146/annurev-ento-112408-085457 10.1371/journal.ppat.1001005 10.1261/rna.5208104 10.1016/j.virusres.2005.10.011 10.1128/JVI.74.11.5123-5132.2000 10.1099/0022-1317-34-2-269
Archives of Virology; Asselin AK, Etebari K et. al.

Aug 7th, 2021 - Native Australian soldier flies, Inopus spp. (Diptera: Stratiomyidae), are agricultural pests of economic importance to the sugarcane industry. A screen of the salivary gland transcriptome of Inopus flavus (James) revealed the presence of viral RNA belonging to a potentially novel member of the family Dicistroviridae. The complete genome sequence consists of 9793 nucleotides with two open readi...

Comparison of the clinical features and outcome of children with hemophagocytic lymphoh...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330039
BMC Infectious Diseases; Mottaghipisheh H, Kalantar K et. al.

Aug 4th, 2021 - Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive inflammation. We aimed to describe the clinical and laboratory findings of HLH patients secondary to Visceral leishmaniasis (VL) and their treatment outcome during a 4-year follow-up period compared to primary HLH. Forty children with primary HLH confirmed by genetic study and 20 children with HLH secondary to VL confirmed by a...

Isolated pelvic bone involvement as a presentation of alveolar echinococcosis.
https://doi.org/10.1016/S1473-3099(21)00254-1
The Lancet. Infectious Diseases; Cambier A, Hayette MP et. al.

Aug 1st, 2021 - Isolated pelvic bone involvement as a presentation of alveolar echinococcosis.|2021|Cambier A,Hayette MP,Léonard P,Kurth W,Lovinfosse P,|therapeutic use,diagnosis,pathology,surgery,diagnosis,parasitology,therapy,isolation & purification,parasitology,pathology,surgery,

Plasmodium falciparum transcription in different clinical presentations of malaria asso...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324851
Nature Communications; Thomson-Luque R, Votborg-Novél L et. al.

Aug 1st, 2021 - Following Plasmodium falciparum infection, individuals can remain asymptomatic, present with mild fever in uncomplicated malaria cases, or show one or more severe malaria symptoms. Several studies have investigated associations between parasite transcription and clinical severity, but no broad conclusions have yet been drawn. Here, we apply a series of bioinformatic approaches based on P. falci...

The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8316339
Nature Communications; Zhang M, Wang C et. al.

Jul 29th, 2021 - The emergence and spread of Plasmodium falciparum parasites resistant to front-line antimalarial artemisinin-combination therapies (ACT) threatens to erase the considerable gains against the disease of the last decade. Here, we develop a large-scale phenotypic screening pipeline and use it to carry out a large-scale forward-genetic phenotype screen in P. falciparum to identify genes allowing pa...

Identification and characterization of a novel virus associated with an eriophyid mite ...
https://doi.org/10.1007/s00705-021-05174-z 10.1099/jgv.0.000757 10.1007/s00705-020-04859-1 10.1111/ppa.12293 10.1093/bioinformatics/btu170 10.1089/cmb.2012.0021 10.1093/bioinformatics/btm404 10.1093/molbev/msn067 10.1093/molbev/msw054 10.3389/fpls.2018.01786 10.1094/PHYTO-07-18-0257-RVW
Archives of Virology; Carvalho Costa L, Stevens K et. al.

Jul 23rd, 2021 - Eriophyid mites are commonly found on the leaf surface of different plant species. In the present study, a novel virus associated with an eriophyid mite species was detected using high-throughput sequencing (HTS) of total RNA from fruit tree leaves, primarily growing under greenhouse conditions. The complete genome sequence was characterized using rapid amplification of cDNA ends followed by Sa...

Current Comment.
https://doi.org/10.1001/jama.2020.18038
JAMA

Jul 21st, 2021 - Current Comment.|2021||history,history,history,microbiology,virology,parasitology,history,

Association between cervical dysplasia and female genital schistosomiasis diagnosed by ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286581
BMC Infectious Diseases; Rafferty H, Sturt AS et. al.

Jul 19th, 2021 - Female genital schistosomiasis (FGS) is a neglected tropical gynaecological disease that affects millions of women in sub-Saharan Africa (SSA). FGS is caused by Schistosoma haematobium, a parasitic carcinogen involved in the pathogenesis of squamous cell carcinoma of the bladder. Cervical cancer incidence and mortality are highest in SSA, where pre-cancerous cervical dysplasia is often detected...

Deformed wing virus variant shift from 2010 to 2016 in managed and feral UK honey bee c...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421296
Archives of Virology; Kevill JL, Stainton KC et. al.

Jul 19th, 2021 - Deformed wing virus (DWV) has been linked to the global decline of honey bees. DWV exists as three master variants (DWV-A, DWV-B, and DWV-C), each with differing outcomes for the honey bee host. Research in the USA showed a shift from DWV-A to DWV-B between 2010 to 2016 in honey bee colonies. Likewise, in the UK, a small study in 2007 found only DWV-A, whereas in 2016, DWV-B was the most preval...

Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270905
Nature Communications; Xu K, Wang Y et. al.

Jul 11th, 2021 - RIFIN, a large family of Plasmodium variant surface antigens, plays a crucial role in malaria pathogenesis by mediating immune suppression through activation of inhibitory receptors such as LAIR1, and antibodies with LAIR1 inserts have been identified that bind infected erythrocytes through RIFIN. However, details of RIFIN-mediated LAIR1 recognition and receptor activation have been unclear. He...

The epidemiology of Plasmodium vivax among adults in the Democratic Republic of the Congo.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263614
Nature Communications; Brazeau NF, Mitchell CL et. al.

Jul 9th, 2021 - Reports of P. vivax infections among Duffy-negative hosts have accumulated throughout sub-Saharan Africa. Despite this growing body of evidence, no nationally representative epidemiological surveys of P. vivax in sub-Saharan Africa have been performed. To overcome this gap in knowledge, we screened over 17,000 adults in the Democratic Republic of the Congo (DRC) for P. vivax using samples from ...

Phthiriasis Palpebrarum.
https://doi.org/10.1056/NEJMicm1913478
The New England Journal of Medicine; Feng X, Qi H

Jul 8th, 2021 - Phthiriasis Palpebrarum.|2021|Feng X,Qi H,|parasitology,complications,diagnosis,parasitology,complications,diagnosis,etiology,

Spatial and Temporal Variability of Visceral Leishmaniasis in Colombia, 2007 to 2018.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274786
The American Journal of Tropical Medicine and Hygiene; Castillo-Castañeda A, Herrera G et. al.

Jul 8th, 2021 - Visceral leishmaniasis (VL) is a neglected tropical disease associated with poverty and is endemic in 56 countries worldwide. Brazil, Venezuela, and Colombia are the most affected countries in South America. In Colombia, the National Public Health Surveillance System (SIVIGILA) consolidates epidemiological information and monitors all VL cases nationwide. However, to date, no studies have inves...

Prevalence of Pathogens in Young Children Presenting to Hospital with Diarrhea from Lam...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274774
The American Journal of Tropical Medicine and Hygiene; Manouana GP, Byrne N et. al.

Jul 8th, 2021 - Diarrheal disease is the second most frequent cause of mortality in children younger than 5 years worldwide, causing more than half a million deaths each year. Our knowledge of the epidemiology of potentially pathogenic agents found in children suffering from diarrhea in sub-Saharan African countries is still patchy, and thereby hinders implementation of effective preventative interventions. Th...

Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity.
https://doi.org/10.1038/s41586-021-03684-z
Nature Mwakingwe-Omari A, Healy SA et. al.

Jul 2nd, 2021 - The global decline in malaria has stalled1, emphasizing the need for vaccines that induce durable sterilizing immunity. Here we optimized regimens for chemoprophylaxis vaccination (CVac), for which aseptic, purified, cryopreserved, infectious Plasmodium falciparum sporozoites (PfSPZ) were inoculated under prophylactic cover with pyrimethamine (PYR) (Sanaria PfSPZ-CVac(PYR)) or chloroquine (CQ) ...

Pangenomics reveals alternative environmental lifestyles among chlamydiae.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242063
Nature Communications; Köstlbacher S, Collingro A et. al.

Jul 1st, 2021 - Chlamydiae are highly successful strictly intracellular bacteria associated with diverse eukaryotic hosts. Here we analyzed metagenome-assembled genomes of the "Genomes from Earth's Microbiomes" initiative from diverse environmental samples, which almost double the known phylogenetic diversity of the phylum and facilitate a highly resolved view at the chlamydial pangenome. Chlamydiae are define...