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About 2,038,423 results

Pulmonary function after segmentectomy versus lobectomy in patients with early-stage no...
https://doi.org/10.1177/03000605211044204
The Journal of International Medical Research; Wang X, Guo H et. al.

Sep 16th, 2021 - Segmentectomy is widely performed for early-stage lung cancer. However, the effects of segmentectomy versus lobectomy on pulmonary function remain unclear. We performed a meta-analysis with the aim of comparing segmentectomy and lobectomy in terms of preservation of pulmonary function in patients with early-stage non-small-cell lung cancer (NSCLC). We conducted a literature search of PubMed usi...

FIGO staging for carcinoma of the vulva: 2021 revision.
https://doi.org/10.1002/ijgo.13880
International Journal of Gynaecology and Obstetrics: the ... Olawaiye AB, Cotler J et. al.

Sep 15th, 2021 - To revise the FIGO staging for carcinoma of the vulva using a new approach that involves analyses of prospectively collected data. The FIGO Committee for Gynecologic Oncology reviewed the recent literature to gain an insight into the impact of the 2009 vulvar cancer staging revision. The Committee resolved to revise the staging with a goal of simplification and actively collaborated with the Un...

Survival outcomes of adjuvant taxanes, platinum plus fluoropyrimidines versus platinum ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434742
World Journal of Surgical Oncology; Wu L, Feng Y et. al.

Sep 12th, 2021 - To evaluate whether the addition of taxanes to platinum and fluoropyrimidines in adjuvant chemotherapy would result in longer survival than platinum plus fluoropyrimidines in gastric cancer patients who received D2 gastrectomy. Data of patients with gastric adenocarcinoma who received D2 gastrectomy and adjuvant chemotherapy with platinum plus fluoropyrimidines or taxanes, platinum plus fluorop...

American Joint Committee on Cancer Staging and Other Platforms to Assess Prognosis and ...
https://doi.org/10.1016/j.cps.2021.05.004
Clinics in Plastic Surgery; Barriera-Silvestrini P, Iacullo J et. al.

Sep 11th, 2021 - The eighth edition of the American Joint Committee on Cancer melanoma staging system relies on assessments of the primary tumor (T), regional lymph nodes (N), and distant metastatic sites (M). Its notable updates include tumor thickness measurements to the nearest 0.1 mm, revision of T1a and T1b definitions, re-evaluation of N category descriptors, increased number of stage III subgroupings, an...

Clinical Diagnosis and Classification: Including Biopsy Techniques and Noninvasive Imag...
https://doi.org/10.1016/j.cps.2021.06.006
Clinics in Plastic Surgery; Vakharia KT

Sep 11th, 2021 - Early detection of melanoma is important in improving patient survival. The treatment of melanoma is multidisciplinary and begins by obtaining an accurate diagnosis. The mainstays of melanoma diagnosis include examination of the lesion and surrounding areas and an excisional biopsy so that a pathologic diagnosis can be obtained. The pathology results will help guide treatment recommendations, a...

Cells of the human intestinal tract mapped across space and time.
https://doi.org/10.1038/s41586-021-03852-1 10.1016/j.devcel.2020.11.010 10.1016/j.stem.2020.11.008 10.1016/j.cell.2020.12.016 10.1038/s41590-020-0602-z 10.1016/j.cell.2018.08.067 10.1016/j.cell.2019.06.029 10.1126/sciimmunol.abb4432 10.1038/s41591-020-1003-4 10.1016/j.cell.2019.10.027 10.1016/j.cell.2019.08.008 10.1371/journal.pone.0079693 10.1038/s41586-019-0992-y 10.1126/science.abc1669 10.1016/j.cell.2020.04.036 10.1152/ajpregu.00638.2003 10.2337/db18-0883 10.1016/j.cell.2018.12.029 10.1210/endrev/bnaa018 10.1111/sji.12305 10.1038/s41593-020-00736-x 10.1053/j.gastro.2020.09.032 10.1053/j.gastro.2017.10.005 10.1053/j.gastro.2018.09.012 10.1038/s41598-017-14835-6 10.1016/j.ydbio.2016.06.042 10.1016/j.smim.2008.02.003 10.1038/s41590-020-0635-3 10.1038/s41586-019-1652-y 10.1016/j.immuni.2019.06.027 10.1016/j.immuni.2018.04.006 10.4049/jimmunol.1501162 10.1111/j.1365-2036.2011.04605.x 10.1038/ng.3760 10.1136/gutjnl-2012-303956 10.1007/s10875-020-00794-7 10.1293/tox.2016-0075 10.1038/s41590-018-0294-9 10.1016/j.immuni.2018.12.010 10.1038/ni.1668 10.1016/j.celrep.2017.01.063 10.1016/j.immuni.2013.11.006 10.4049/jimmunol.1501191 10.1016/j.immuni.2016.09.001 10.1038/s41590-019-0505-z 10.1126/science.1260419 10.1136/gutjnl-2017-314817 10.1093/gigascience/giaa151 10.1126/science.aad0501 10.1093/nar/gkaa1204 10.1126/science.1161431 10.1038/s41586-019-1154-y 10.1016/j.cell.2020.08.003 10.1016/j.cmet.2013.06.008 10.1016/j.scr.2016.04.011 10.1016/j.celrep.2017.05.019 10.1371/journal.pone.0176031 10.1158/2326-6066.CIR-19-0796 10.1371/journal.pone.0025391 10.1084/jem.20050879 10.4049/jimmunol.1900592 10.1038/s41422-020-00445-x 10.1016/j.cell.2017.02.021 10.1523/JNEUROSCI.0361-11.2011 10.1038/s41419-019-1540-2 10.1016/j.immuni.2018.12.009 10.1126/science.aau0964 10.1126/science.aam7511 10.1038/nmeth.3800 10.1038/nmeth.3545 10.1093/nar/gkv007 10.1038/s41587-020-0591-3 10.1186/s13059-019-1663-x 10.1126/sciimmunol.abe6291 10.1093/nar/gkt382 10.1093/bioinformatics/btu138 10.1093/bioinformatics/btv359 10.1038/s41596-020-0292-x 10.1038/s41586-018-0698-6 10.1371/journal.pgen.1000214 10.1016/j.ajhg.2014.03.004 10.1086/519024 10.1038/s41588-018-0278-6
Nature Elmentaite R, Kumasaka N et. al.

Sep 10th, 2021 - The cellular landscape of the human intestinal tract is dynamic throughout life, developing in utero and changing in response to functional requirements and environmental exposures. Here, to comprehensively map cell lineages, we use single-cell RNA sequencing and antigen receptor analysis of almost half a million cells from up to 5 anatomical regions in the developing and up to 11 distinct anat...

Vaccinia virus-based vaccines confer protective immunity against SARS-CoV-2 virus in Sy...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428573
PloS One; Kulkarni R, Chen WC et. al.

Sep 10th, 2021 - COVID-19 in humans is caused by Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that belongs to the beta family of coronaviruses. SARS-CoV-2 causes severe respiratory illness in 10-15% of infected individuals and mortality in 2-3%. Vaccines are urgently needed to prevent infection and to contain viral spread. Although several mRNA- and adenovirus-based vaccines are highly effective...

New insight into the mechanism of granulocyte colony-stimulating factor (G-CSF) that in...
https://doi.org/10.1080/16078454.2021.1965725
Hematology (Amsterdam, Netherlands); Theyab A, Algahtani M et. al.

Sep 9th, 2021 - Over the past 20 years, granulocyte colony-stimulating factor (G-CSF) has driven the attention of researchers as a therapeutic agent for curing patients suffering from neutropenia. Despite the successful use of G-CSF, it currently requires daily injections, which are inconvenient, expensive, and distressing for children. Therefore, an alternative strategy for using G-CSF for treatment is needed...

Variations and characteristics of the various clinical phenotypes in a cohort of Nigeri...
https://doi.org/10.1080/16078454.2021.1972242
Hematology (Amsterdam, Netherlands); Duru A, Madu AJ et. al.

Sep 9th, 2021 - Sickle cell anaemia affects about 4 million people across the globe, making it an inherited disorder of public health importance. Red cell lysis consequent upon haemoglobin crystallization and repeated sickling leads to anaemia and a baseline strain on haemopoiesis. Vaso-occlusion and haemolysis underlies majority of the chronic complications of sickle cell. We evaluated the clinical and labora...

A case of a patient characterized by t(8;22)(p11;q11) and BCR/FGFR1 fusion gene, who wa...
https://doi.org/10.1080/16078454.2021.1971889
Hematology (Amsterdam, Netherlands); Chen X, Huang L et. al.

Sep 9th, 2021 - Objective: The 8p11 myeloproliferative syndrome [EMS] is a rare myeloproliferative disorder which usually develops rapidly with chromosomal translocation of the fibroblast growth factor receptor 1 gene. The gene has 15 fusion partners, including the breakpoint cluster region (BCR) gene on chromosome 22. Of all the tests available, chromosome karyotype determination is the most important for the...

Long-term follow-up of 46 cases of primary fallopian tube carcinoma: a single institute...
https://doi.org/10.21037/apm-21-2083
Annals of Palliative Medicine; Li S, Yu M et. al.

Sep 8th, 2021 - Primary fallopian tube carcinoma (PFTC) is a rare malignancy. In recent years the incidence of PFTC has been rising. This study retrospectively analyzed 46 cases of PFTC to identify prognostic factors that may impact the survival of patients with PFTC and explored the clinical characteristics. The clinical data of patients who had undergone surgery and adjuvant chemotherapy in Ren Ji Hospital, ...

Mutational characteristics of bone metastasis of lung cancer.
https://doi.org/10.21037/apm-21-1595
Annals of Palliative Medicine; Huang X, Shi X et. al.

Sep 8th, 2021 - Roughly 30-40% of lung cancer (LC) patients develop bone metastasis during the course of disease. The genetic differences between primary LC and matched bone metastasis are not yet fully understood. A total of 40 LC patients with bone metastasis were collected and 450 targeted cancer-related genes were sequenced for genomic-alteration (GA) identification. Among the 40 LC patients, 33 had adenoc...

Ischemic stroke induces cardiac dysfunction and alters transcriptome profile in mice.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418010
BMC Genomics; Chen J, Gong J et. al.

Sep 6th, 2021 - Stroke can induce cardiac dysfunction in the absence of primary cardiac disease; however, the mechanisms underlying the interaction between the neurological deficits and the heart are poorly understood. The objective of this study was to investigate the effects of stroke on cardiac function and to identify the transcriptome characteristics of the heart. Stroke significantly decreased heart weig...

Higher BMI predicts liver fibrosis among obese children and adolescents with NAFLD - an...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414665
BMC Pediatrics; Moran-Lev H, Cohen S et. al.

Sep 5th, 2021 - Non-alcoholic fatty liver disease (NAFLD) can range from simple steatosis to steatohepatitis with or without fibrosis. The predictors for liver fibrosis and the effect of nutritional intervention on hepatic fibrosis in pediatric population are not well established. We aimed to investigate the predictors for liver fibrosis and the effects of short-term nutritional intervention on steatosis and f...

Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-depend...
https://doi.org/10.1038/s41467-021-25453-2 10.1016/S0140-6736(18)32279-7 10.1097/BRS.0b013e3181a01b3f 10.1371/journal.pone.0110768 10.1007/s12195-009-0072-8 10.1038/s41598-017-11960-0 10.1016/j.matbio.2018.03.019 10.1002/jor.21153 10.1111/acel.12927 10.1016/j.matbio.2019.02.004 10.1016/j.cell.2017.05.015 10.1038/nrm3823 10.7554/eLife.52570 10.3390/jcm8040433 10.7554/eLife.54693 10.1111/acel.12344 10.1016/j.ebiom.2017.04.013 10.1038/nm.4324 10.1016/j.bcp.2006.02.009 10.1016/j.lfs.2015.07.015 10.1038/ncomms14532 10.1038/nm.4385 10.1038/s41591-018-0092-9 10.1016/j.ebiom.2019.08.069 10.1016/j.ebiom.2018.12.052 10.1111/acel.13148 10.1097/00007632-199005000-00012 10.1038/sj.onc.1207074 10.1038/35092592 10.1038/nrc3960 10.1186/1747-1028-2-10 10.1146/annurev-pathol-121808-102144 10.1038/s41598-018-23196-7 10.1016/j.mbplus.2020.100036 10.1152/japplphysiol.01322.2013 10.22203/eCM.v021a01 10.1016/j.matbio.2020.09.003 10.1002/jor.22789 10.1080/03008207.2019.1665034 10.1038/s41596-019-0128-8 10.1111/acel.12950 10.1016/j.joca.2010.05.025 10.1093/neuros/nyw078 10.1038/s41593-019-0372-9 10.1080/10520290601005298 10.1111/acel.12771 10.1038/ncomms2226 10.1101/gad.271882.115 10.1002/jbmr.3714 10.1111/acel.13006 10.1016/j.mad.2017.08.007 10.1002/jbmr.3908 10.1002/jbmr.4019 10.1002/jbmr.3293 10.1111/acel.12458 10.1111/acel.12971 10.1038/s41419-018-1246-x 10.1002/jbmr.3931 10.18632/aging.101206 10.1016/j.mad.2019.03.005 10.1096/fj.201900815RR 10.1038/s41467-020-15719-6 10.1172/JCI86249 10.1016/B978-012369454-6/50074-1 10.1002/jor.23583 10.1016/j.expneurol.2012.03.007 10.1016/j.matbio.2019.10.007
Nature Communications; Novais EJ, Tran VA et. al.

Sep 5th, 2021 - Intervertebral disc degeneration is highly prevalent within the elderly population and is a leading cause of chronic back pain and disability. Due to the link between disc degeneration and senescence, we explored the ability of the Dasatinib and Quercetin drug combination (D + Q) to prevent an age-dependent progression of disc degeneration in mice. We treated C57BL/6 mice beginning at 6, 14, an...

Prevalence of abnormal cardiovascular magnetic resonance findings in recovered patients...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414035
Journal of Cardiovascular Magnetic Resonance : Official J... Kim JY, Han K et. al.

Sep 5th, 2021 - The prevalence of abnormal cardiovascular magnetic resonance (CMR) findings in recovered coronavirus disease 2019 (COVID-19) patients is unclear. This study aimed to investigate the prevalence of abnormal CMR findings in recovered COVID-19 patients. A systematic literature search was performed to identify studies that report the prevalence of abnormal CMR findings in recovered COVID-19 patients...

Single allele loss-of-function mutations select and sculpt conditional cooperative netw...
https://doi.org/10.1038/s41467-021-25467-w 10.1038/nature17676 10.1038/emboj.2013.19 10.1038/nature08822 10.1126/science.1219580 10.1016/j.cell.2011.02.013 10.18632/oncotarget.682 10.1371/journal.pone.0027425 10.1073/pnas.1613859113 10.1016/j.gde.2015.04.007 10.1158/0008-5472.CAN-16-1586 10.1073/pnas.1701512114 10.1038/ng.3905 10.1038/s41467-020-16936-9 10.1038/ng.3817 10.1158/0008-5472.CAN-10-0738 10.1158/0008-5472.CAN-09-1135 10.1126/science.1163040 10.1371/journal.pone.0024668 10.1016/j.ccell.2014.09.013 10.1007/s12079-017-0415-5 10.1158/0008-5472.CAN-15-3150 10.1038/ncomms11479 10.1016/j.ccr.2014.03.016 10.1073/pnas.1210353110 10.1016/j.cell.2015.09.033 10.1038/s41596-018-0103-9 10.1158/1078-0432.CCR-15-0159 10.1038/ng.3175 10.1038/nm.3650 10.1016/S0002-9440(10)64269-1 10.1007/s00018-014-1644-x 10.1016/j.stem.2013.04.012 10.1016/j.stem.2008.08.001 10.1073/pnas.2136825100 10.1038/nrc1186 10.1038/nbt1385 10.1074/jbc.RA120.014018 10.1534/genetics.112.142802 10.1016/j.ccell.2018.08.008 10.1016/j.cell.2018.02.060 10.1038/nature12912 10.1093/nar/gkx956 10.1016/j.febslet.2011.05.036 10.1126/science.1162981 10.1038/s41388-018-0402-1 10.1016/j.celrep.2016.11.028 10.1016/j.celrep.2016.05.046 10.1126/science.aax0364 10.1073/pnas.1320428111 10.1016/j.cellsig.2005.06.016 10.1126/science.aaw9032 10.1073/pnas.0712169105 10.1038/ncomms5961 10.1002/pmic.201400342 10.1038/nature10983 10.1073/pnas.1206062109 10.1016/j.ccell.2016.04.003 10.1016/j.ccell.2016.04.011 10.1038/nature17157 10.1016/j.cell.2015.11.062 10.1016/j.cell.2011.04.029 10.1371/journal.pgen.1007135 10.1016/S0002-9440(10)63333-0 10.1158/1078-0432.CCR-14-1348 10.1016/j.celrep.2018.08.053 10.1038/nm0809-842 10.1002/jcp.22526 10.1016/j.ccr.2012.03.041 10.1007/s10549-015-3476-2 10.1038/ng.990 10.1172/JCI59309 10.1093/hmg/11.13.1549 10.1038/334119a0 10.1126/science.1102160 10.1038/nature25459 10.1158/1078-0432.CCR-17-2343 10.1038/ng.3251 10.1016/j.celrep.2018.09.056 10.1093/nar/gkm226 10.1371/journal.pone.0013984
Nature Communications; Schachter NF, Adams JR et. al.

Sep 4th, 2021 - The most common events in breast cancer (BC) involve chromosome arm losses and gains. Here we describe identification of 1089 gene-centric common insertion sites (gCIS) from transposon-based screens in 8 mouse models of BC. Some gCIS are driver-specific, others driver non-specific, and still others associated with tumor histology. Processes affected by driver-specific and histology-specific mut...

Genome-wide sequencing-based identification of methylation quantitative trait loci and ...
https://doi.org/10.1038/s41467-021-25517-3 10.1073/pnas.0806560105 10.1016/j.ajhg.2011.03.003 10.1186/gb-2012-13-6-r43 10.1038/ng.286 10.1186/gb-2012-13-10-172 10.4161/epi.5.7.12960 10.1073/pnas.87.12.4692 10.1186/1471-2164-15-145 10.1038/s41467-017-01818-4 10.1038/nn.4181 10.1186/s13059-015-0842-7 10.1371/journal.pgen.1004958 10.1016/j.psc.2009.12.003 10.1038/s41588-018-0059-2 10.1038/s41588-019-0497-5 10.1038/s41593-018-0197-y 10.1038/nn.4399 10.1038/ng.3538 10.1038/s41588-018-0092-1 10.1038/ng.3367 10.1038/s41467-019-12228-z 10.1038/mp.2011.174 10.1097/MOP.0b013e32832925cc 10.1038/ejhg.2008.106 10.1038/nn.3607 10.1038/nrn.2017.125 10.1038/s41598-019-45839-z 10.1186/gb-2012-13-10-r83 10.1038/nature14248 10.1002/humu.20822 10.1016/j.ajhg.2010.11.011 10.1038/nbt.2487 10.1056/NEJMra1402513 10.1038/ncomms13507 10.1016/j.neuron.2019.05.013 10.1038/nature10442 10.1038/nature05913 10.1016/0092-8674(80)90237-8 10.1038/ng.3404 10.4161/epi.23924 10.1186/s13059-019-1805-1 10.1016/S1521-6616(03)00203-1 10.1196/annals.1395.005 10.1186/s13073-016-0354-4 10.1016/j.tig.2015.03.002 10.1126/sciadv.aau6190 10.1016/j.biopsych.2006.06.019 10.1016/j.biopsych.2004.10.016 10.1016/j.neuron.2015.10.047 10.1093/bioinformatics/bty167 10.1093/bioinformatics/btu314 10.1093/bioinformatics/btp352 10.1186/s12859-021-04142-3 10.1371/journal.pgen.1000529 10.1186/1471-2105-9-540 10.1086/519795 10.1093/bioinformatics/bts163 10.1093/ije/dyr238 10.1073/pnas.1530509100 10.1038/s41593-018-0297-8 10.1093/nar/gkv007 10.1214/16-AOAS920
Nature Communications; Perzel Mandell KA, Eagles NJ et. al.

Sep 4th, 2021 - DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed DNAm in 344 samples of human postmortem brain tissue from neurotypical subjects and individuals with schizophrenia. We identify genetic influence on local methylation levels throughout the genome, both at CpG sites and CpH...

Functional characterization of T2D-associated SNP effects on baseline and ER stress-res...
https://doi.org/10.1038/s41467-021-25514-6 10.1172/JCI29103 10.1016/j.tig.2017.01.010 10.1038/nature18642 10.1038/s41588-018-0241-6 10.1073/pnas.1317023110 10.1016/j.cmet.2010.09.012 10.2337/db18-0393 10.1038/ng.2870 10.1016/j.ajhg.2018.02.020 10.1016/j.molmet.2017.06.001 10.1146/annurev-biochem-072909-095555 10.1016/j.semcdb.2020.04.006 10.1172/JCI79264 10.1007/s11745-003-1038-4 10.1007/s00125-019-4914-1 10.2174/157339912799424564 10.1007/s00125-013-2855-7 10.1038/ng.3531 10.1038/nbt.2137 10.1016/j.cell.2016.04.027 10.1101/gr.190090.115 10.1038/s41467-019-10439-y 10.1093/nar/gkw1133 10.1371/journal.pgen.1004633 10.2337/db12-0972 10.1016/j.cmet.2005.08.004 10.1210/jc.2015-2860 10.1038/ncomms12631 10.1111/j.1463-1326.2007.00782.x 10.1038/ng890 10.1038/s41467-018-06249-3 10.1074/jbc.M109.064659 10.1096/fj.14-256743 10.1038/ng.3437 10.1016/j.molmet.2016.01.002 10.1101/cshperspect.a007666 10.2337/db13-0571 10.1038/78085 10.1016/0092-8674(89)90019-6 10.1074/jbc.M117.796920 10.1038/s41598-019-41604-4 10.1074/jbc.M110.170142 10.1074/jbc.M116.769877 10.1172/JCI122445 10.1007/s00125-019-05060-z 10.1111/jdi.13218 10.1038/s41574-020-0355-7 10.1016/j.biocel.2005.09.018 10.1038/sj.cdd.4401373 10.1016/j.molmet.2019.06.012 10.1007/s00125-018-4735-7 10.2337/db18-0030 10.1210/me.2009-0513 10.2174/157339913804143225 10.1073/pnas.1917190117 10.1093/nar/23.10.1758 10.1186/gb-2011-12-12-236 10.1038/ng.530 10.1038/s41588-019-0457-0 10.1038/s41467-019-09975-4 10.1016/j.molmet.2018.07.007 10.1371/journal.pone.0009575 10.1074/jbc.M113.507194 10.1038/s41467-020-18581-8 10.1371/journal.pgen.1005061 10.1038/s41588-019-0505-9 10.1038/s41588-019-0524-6 10.1016/j.cell.2016.07.049 10.1016/j.cell.2012.12.018 10.1038/s41467-017-00366-1 10.1038/s41467-019-13555-x 10.1016/j.celrep.2014.03.011 10.1038/s41588-019-0373-3 10.1073/pnas.1104997108 10.1186/s13059-019-1916-8 10.1101/gr.168872.113 10.1038/ng.2649 10.1038/ncomms14550 10.1101/gr.139618.112 10.1016/S0378-1119(99)00384-4 10.1101/gr.249789.119 10.1038/nature04696 10.1016/j.gde.2016.01.001 10.1016/j.celrep.2018.12.083 10.1086/519795 10.1186/s13059-014-0550-8 10.1016/j.molcel.2010.05.004 10.1093/bioinformatics/btu170 10.1186/gb-2008-9-9-r137 10.1038/nprot.2009.97 10.1093/nar/gkw1064
Nature Communications; Khetan S, Kales S et. al.

Sep 4th, 2021 - Genome-wide association studies (GWAS) have linked single nucleotide polymorphisms (SNPs) at >250 loci in the human genome to type 2 diabetes (T2D) risk. For each locus, identifying the functional variant(s) among multiple SNPs in high linkage disequilibrium is critical to understand molecular mechanisms underlying T2D genetic risk. Using massively parallel reporter assays (MPRA), we test the c...

Long non-coding RNA NR2F1-AS1 induces breast cancer lung metastatic dormancy by regulat...
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Sep 4th, 2021 - Disseminated tumor cells often fall into a long term of dormant stage, characterized by decreased proliferation but sustained survival, in distant organs before awakening for metastatic growth. However, the regulatory mechanism of metastatic dormancy and awakening is largely unknown. Here, we show that the epithelial-like and mesenchymal-like subpopulations of breast cancer stem-like cells (BCS...